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Aliases for NUDT5 Gene

Aliases for NUDT5 Gene

  • Nudix Hydrolase 5 2 3 5
  • Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5 2 3
  • Nuclear ATP-Synthesis Protein NUDIX5 3 4
  • 8-Oxo-DGDP Phosphatase 3 4
  • HNUDT5 3 4
  • YSA1H 3 4
  • Nucleoside Diphosphate-Linked Moiety X Motif 5 4
  • ADP-Sugar Pyrophosphatase 3
  • Nudix Motif 5 4
  • EC 3.6.1.13 4
  • EC 3.6.1.58 4
  • EC 2.7.7.96 4
  • NUDIX5 4
  • YSAH1 3
  • YSA1 3

External Ids for NUDT5 Gene

Previous GeneCards Identifiers for NUDT5 Gene

  • GC10M012153
  • GC10M012357
  • GC10M012213
  • GC10M012249
  • GC10M012126

Summaries for NUDT5 Gene

Entrez Gene Summary for NUDT5 Gene

  • This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. [provided by RefSeq, Aug 2013]

GeneCards Summary for NUDT5 Gene

NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene. Among its related pathways are Metabolism and Purine metabolism. GO annotations related to this gene include hydrolase activity and snoRNA binding.

UniProtKB/Swiss-Prot for NUDT5 Gene

  • Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate (PubMed:27257257). In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP (PubMed:10567213, PubMed:10722730, PubMed:19699693, PubMed:21389046, PubMed:17052728). Can also hydrolyze other nucleotide sugars with low activity (PubMed:19699693, PubMed:21389046). In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45 (PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257). Does not play a role in U8 snoRNA decapping activity (By similarity). Binds U8 snoRNA (By similarity).

Gene Wiki entry for NUDT5 Gene

Additional gene information for NUDT5 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUDT5 Gene

Genomics for NUDT5 Gene

Regulatory Elements for NUDT5 Gene

Enhancers for NUDT5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10H012240 1.6 FANTOM5 Ensembl ENCODE dbSUPER 9.2 -47.1 -47128 5 CTCF PKNOX1 MAX BMI1 EBF1 BATF RELA POLR2A EED ATF7 CAMK1D MIR548Q NUDT5 UPF2 SEC61A2 ENSG00000228302
GH10H012128 1 ENCODE 9.2 +66.5 66519 2 ATF1 MLX ZFP64 ARID4B SIN3A DMAP1 YY1 ZNF121 GLIS2 ZNF143 DHTKD1 UPF2 SEC61A2 NUDT5 GC10P012129
GH10H012121 0.9 ENCODE 9.3 +73.1 73134 2 HDGF PKNOX1 TBL1XR1 RB1 BMI1 BATF ZNF207 ATF7 ETV6 RUNX3 NUDT5 SEC61A2 DHTKD1 PIR36950 GC10P012129
GH10H012193 1.1 ENCODE 7.4 +0.6 592 3 PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ZNF766 UPF2 NUDT5 CAMK1D CDC123 PIR56929
GH10H012194 0.8 ENCODE 9.7 +2.7 2668 0 YY1 ZNF366 SCRT2 FOS ZNF362 USF2 CEBPB ZEB2 PRDM6 KLF16 SEC61A2 DHTKD1 NUDT5 CDC123 PIR56929
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NUDT5 on UCSC Golden Path with GeneCards custom track

Promoters for NUDT5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000024520 44 3001 PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ZNF766

Genomic Location for NUDT5 Gene

Chromosome:
10
Start:
12,165,325 bp from pter
End:
12,196,144 bp from pter
Size:
30,820 bases
Orientation:
Minus strand

Genomic View for NUDT5 Gene

Genes around NUDT5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NUDT5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NUDT5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUDT5 Gene

Proteins for NUDT5 Gene

  • Protein details for NUDT5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UKK9-NUDT5_HUMAN
    Recommended name:
    ADP-sugar pyrophosphatase
    Protein Accession:
    Q9UKK9
    Secondary Accessions:
    • A8K516
    • Q6IAG0
    • Q9UH49

    Protein attributes for NUDT5 Gene

    Size:
    219 amino acids
    Molecular mass:
    24328 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    • Homodimer (PubMed:27257257, PubMed:17052728, PubMed:18462755, PubMed:21768126). Interacts with PARG (PubMed:27257257).

    Three dimensional structures from OCA and Proteopedia for NUDT5 Gene

neXtProt entry for NUDT5 Gene

Post-translational modifications for NUDT5 Gene

  • Phosphorylation at Thr-45 is required for homodimer stability; dephosphorylation results in destabilization of the homodimer. Dephosphorylation at Thr-45 promotes the ATP-synthesis activity.
  • Ubiquitination at Lys27, posLast=175175, Lys210, and posLast=218218
  • Modification sites at PhosphoSitePlus

Antibody Products

  • R&D Systems Antibodies for NUDT5 (ADP-Sugar Pyrophosphatase/NUDT5)

No data available for DME Specific Peptides for NUDT5 Gene

Domains & Families for NUDT5 Gene

Gene Families for NUDT5 Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for NUDT5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UKK9

UniProtKB/Swiss-Prot:

NUDT5_HUMAN :
  • Belongs to the Nudix hydrolase family.
Family:
  • Belongs to the Nudix hydrolase family.
genes like me logo Genes that share domains with NUDT5: view

Function for NUDT5 Gene

Molecular function for NUDT5 Gene

GENATLAS Biochemistry:
nudix (nucleoside diphosphate linked moiety X)-type motif 5,hydrolase,NDP- sugar hydrolase,putative mouse cleaning gene whose functions is to cleanse the cell of potentially deleterious endogenous metabolites and to modulate the accumulation of intermediates in biochemical pathways
UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=2.1 uM for 8-oxo-dGDP {ECO:0000269 PubMed:19699693}; KM=2.9 uM for 8-oxo-dADP {ECO:0000269 PubMed:19699693}; KM=8.8 uM for 2-oxo-dADP {ECO:0000269 PubMed:19699693}; KM=4.0 uM for 5-CHO-dUDP {ECO:0000269 PubMed:19699693}; KM=7.6 uM for dGDP {ECO:0000269 PubMed:19699693}; KM=12.6 uM for dADP {ECO:0000269 PubMed:19699693}; KM=3.8 uM for 8-oxo-dGDP (at pH 8.0) {ECO:0000269 PubMed:21389046}; KM=3.5 uM for 8-oxo-dGDP (at pH 10.0) {ECO:0000269 PubMed:21389046}; KM=1.9 uM for ADP-D-ribose (at pH 8.0) {ECO:0000269 PubMed:21389046}; KM=36 uM for 8-oxo-dGTP (at pH 10.0) {ECO:0000269 PubMed:21389046}; KM=42.6 uM for ADP-D-ribose (in the presence of diphosphate) {ECO:0000269 PubMed:27257257}; Vmax=11 pmol/min/ug enzyme with 8-oxo-dGDP as substrate (at pH 8.0) {ECO:0000269 PubMed:21389046}; Vmax=2400 pmol/min/ug enzyme with ADP-D-ribose as substrate (at pH 8.0) {ECO:0000269 PubMed:21389046}; Vmax=46 pmol/min/ug enzyme with 8-oxo-dGDP as substrate (at pH 10.0) {ECO:0000269 PubMed:21389046}; Vmax=1.7 pmol/min/ug enzyme with 8-oxo-dGTP as substrate (at pH 10.0) {ECO:0000269 PubMed:21389046}; Note=kcat is 0.369 min(-1) for 8-OH-dGDP. kcat is 0.538 min(-1) for 8-OH-dADP. kcat is 0.226 min(-1) for 2-OH-dADP. kcat is 0.209 min(-1) for 5-CHO-dUDP. kcat is 0.929 min(-1) for dGDP. kcat is 0.365 min(-1) for dADP. {ECO:0000269 PubMed:19699693};
UniProtKB/Swiss-Prot CatalyticActivity:
ATP + D-ribose 5-phosphate = diphosphate + ADP-D-ribose.
UniProtKB/Swiss-Prot CatalyticActivity:
ADP-D-ribose + H(2)O = AMP + D-ribose 5-phosphate.
UniProtKB/Swiss-Prot CatalyticActivity:
8-oxo-dGDP + H(2)O = 8-oxo-dGMP + phosphate.
UniProtKB/Swiss-Prot Function:
Enzyme that can either act as an ADP-sugar pyrophosphatase in absence of diphosphate or catalyze the synthesis of ATP in presence of diphosphate (PubMed:27257257). In absence of diphosphate, hydrolyzes with similar activities various modified nucleoside diphosphates such as ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP (PubMed:10567213, PubMed:10722730, PubMed:19699693, PubMed:21389046, PubMed:17052728). Can also hydrolyze other nucleotide sugars with low activity (PubMed:19699693, PubMed:21389046). In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5-phosphate. Nuclear ATP synthesis takes place when dephosphorylated at Thr-45 (PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257). Does not play a role in U8 snoRNA decapping activity (By similarity). Binds U8 snoRNA (By similarity).
UniProtKB/Swiss-Prot Induction:
Overexpressed in cancer patients with a poor outcome.

Enzyme Numbers (IUBMB) for NUDT5 Gene

Gene Ontology (GO) - Molecular Function for NUDT5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000287 magnesium ion binding IDA 18462755
GO:0003723 RNA binding IEA --
GO:0005515 protein binding IPI 27257257
GO:0016740 transferase activity IEA --
GO:0016779 nucleotidyltransferase activity IDA 27257257
genes like me logo Genes that share ontologies with NUDT5: view
genes like me logo Genes that share phenotypes with NUDT5: view

Animal Model Products

  • Taconic Biosciences Mouse Models for NUDT5

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for NUDT5
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NUDT5 Gene

Localization for NUDT5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NUDT5 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for NUDT5 gene
Compartment Confidence
extracellular 5
nucleus 5
cytosol 5
cytoskeleton 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centrosome (2)
  • Nucleus (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for NUDT5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular NAS 10567213
GO:0005634 nucleus IDA,IEA 21630459
GO:0005829 cytosol TAS --
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with NUDT5: view

Pathways & Interactions for NUDT5 Gene

genes like me logo Genes that share pathways with NUDT5: view

Pathways by source for NUDT5 Gene

1 KEGG pathway for NUDT5 Gene

Gene Ontology (GO) - Biological Process for NUDT5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006139 nucleobase-containing compound metabolic process IEA --
GO:0006338 chromatin remodeling IDA 27257257
GO:0009117 nucleotide metabolic process NAS 10567213
GO:0009191 ribonucleoside diphosphate catabolic process IDA 18462755
GO:0019303 D-ribose catabolic process NAS 10567213
genes like me logo Genes that share ontologies with NUDT5: view

No data available for SIGNOR curated interactions for NUDT5 Gene

Drugs & Compounds for NUDT5 Gene

(4) Drugs for NUDT5 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Water Approved Pharma 0
Adenosine monophosphate Approved Nutra 0
Magnesium Nutra 0

(9) Additional Compounds for NUDT5 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
8-oxo-dGDP
8-Oxo-dGMP
  • 8-Oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate
  • 8OG
Adenosine diphosphate ribose
  • (Rib5)ppA
  • 5-(Adenosine 5'-pyrophosphoryl)-D-ribose
  • A5'pp5Rib
  • Adenosine 5'-diphosphoribose
  • Adenosine diphosphate ribose
20762-30-5
D-Ribose 5-phosphate
  • D-Ribose 5-phosphate
  • D-Ribose-5-P
  • D-Ribose-5-phosphate
  • D-Ribose-5-phosphorate
  • D-Ribose-5-phosphoric acid
3615-55-2
D-Ribulose 5-phosphate
  • alpha-D-Ribose 5-phosphate
  • D-Ribulose 5-phosphate
  • Erythro-Pentulose 5-phosphate
  • Ribulose 5-phosphate
  • Ribulose phosphate
4151-19-3
genes like me logo Genes that share compounds with NUDT5: view

Transcripts for NUDT5 Gene

Unigene Clusters for NUDT5 Gene

Nudix (nucleoside diphosphate linked moiety X)-type motif 5:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for NUDT5
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for NUDT5 Gene

No ASD Table

Relevant External Links for NUDT5 Gene

GeneLoc Exon Structure for
NUDT5
ECgene alternative splicing isoforms for
NUDT5

Expression for NUDT5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NUDT5 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NUDT5 Gene

This gene is overexpressed in Whole Blood (x4.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for NUDT5 Gene



Protein tissue co-expression partners for NUDT5 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of NUDT5 Gene:

NUDT5

SOURCE GeneReport for Unigene cluster for NUDT5 Gene:

Hs.555956

mRNA Expression by UniProt/SwissProt for NUDT5 Gene:

Q9UKK9-NUDT5_HUMAN
Tissue specificity: Widely expressed. Most abundant in liver.

Evidence on tissue expression from TISSUES for NUDT5 Gene

  • Blood(4.2)
  • Nervous system(4)
  • Lung(3.1)
  • Skin(3.1)
  • Eye(2.2)
genes like me logo Genes that share expression patterns with NUDT5: view

Primer Products

No data available for Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for NUDT5 Gene

Orthologs for NUDT5 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for NUDT5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NUDT5 33 34
  • 99.24 (n)
dog
(Canis familiaris)
Mammalia NUDT5 33 34
  • 86.91 (n)
cow
(Bos Taurus)
Mammalia NUDT5 34
  • 84 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia NUDT5 34
  • 82 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nudt5 33
  • 81.89 (n)
mouse
(Mus musculus)
Mammalia Nudt5 33 16 34
  • 80.89 (n)
oppossum
(Monodelphis domestica)
Mammalia NUDT5 34
  • 69 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC426368 33
  • 72.15 (n)
NUDT5 34
  • 63 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia NUDT5 34
  • 70 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia nudt5 33
  • 66.5 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.17284 33
zebrafish
(Danio rerio)
Actinopterygii nudt5 33 34
  • 64.04 (n)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9208 33
worm
(Caenorhabditis elegans)
Secernentea ndx-2 33 34
  • 46.56 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes YSA1 33 34
  • 49.07 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0B09306g 33
  • 48.82 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPBP35G2.12 33
  • 48.62 (n)
Species where no ortholog for NUDT5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for NUDT5 Gene

ENSEMBL:
Gene Tree for NUDT5 (if available)
TreeFam:
Gene Tree for NUDT5 (if available)

Paralogs for NUDT5 Gene

Pseudogenes.org Pseudogenes for NUDT5 Gene

genes like me logo Genes that share paralogs with NUDT5: view

No data available for Paralogs for NUDT5 Gene

Variants for NUDT5 Gene

Sequence variations from dbSNP and Humsavar for NUDT5 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000109990 -- 12,186,150(+) CACCA(C/T)TGTAA intron-variant
rs1000148298 -- 12,191,632(+) TATAG(C/T)CCCGG intron-variant
rs1000222692 -- 12,179,203(+) TGTAC(A/G)ACCAG intron-variant
rs1000234817 -- 12,194,378(+) ACTGC(C/T)CCTGT intron-variant, upstream-variant-2KB
rs1000276893 -- 12,196,593(+) ACTTT(C/T)AGAAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for NUDT5 Gene

Variant ID Type Subtype PubMed ID
nsv1035709 CNV gain 25217958
nsv5820 CNV insertion 18451855
nsv982893 CNV duplication 23825009

Variation tolerance for NUDT5 Gene

Residual Variation Intolerance Score: 39.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.78; 16.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NUDT5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NUDT5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUDT5 Gene

Disorders for NUDT5 Gene

Relevant External Links for NUDT5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NUDT5

No disorders were found for NUDT5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NUDT5 Gene

Publications for NUDT5 Gene

  1. Cloning, expression and characterization of YSA1H, a human adenosine 5'-diphosphosugar pyrophosphatase possessing a MutT motif. (PMID: 10567213) Gasmi L … McLennan AG (The Biochemical journal 1999) 3 4 22 60
  2. ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling. (PMID: 27257257) Wright RH … Beato M (Science (New York, N.Y.) 2016) 3 4 60
  3. Cleavage of oxidized guanine nucleotide and ADP sugar by human NUDT5 protein. (PMID: 21389046) Ito R … Hayakawa H (Journal of biochemistry 2011) 3 4 60
  4. Diverse substrate recognition and hydrolysis mechanisms of human NUDT5. (PMID: 21768126) Arimori T … Yamagata Y (Nucleic acids research 2011) 3 4 60
  5. Suppression of mutagenesis by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate (7,8-dihydro-8-oxo-2'-deoxyguanosine 5'-triphosphate) by human MTH1, MTH2, and NUDT5. (PMID: 20144704) Hori M … Kamiya H (Free radical biology & medicine 2010) 3 22 60

Products for NUDT5 Gene

Sources for NUDT5 Gene

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