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Aliases for NUDT22 Gene

Aliases for NUDT22 Gene

  • Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 22 2 3
  • Nudix Motif 22 4

External Ids for NUDT22 Gene

Previous GeneCards Identifiers for NUDT22 Gene

  • GC11P063751
  • GC11P063993
  • GC11P060322

Summaries for NUDT22 Gene

GeneCards Summary for NUDT22 Gene

NUDT22 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 22) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUDT22 Gene

Genomics for NUDT22 Gene

Regulatory Elements for NUDT22 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for NUDT22 Gene

64,225,941 bp from pter
64,230,686 bp from pter
4,746 bases
Plus strand

Genomic View for NUDT22 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NUDT22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUDT22 Gene

Proteins for NUDT22 Gene

  • Protein details for NUDT22 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nucleoside diphosphate-linked moiety X motif 22
    Protein Accession:
    Secondary Accessions:
    • C9JY06
    • Q71RD5

    Protein attributes for NUDT22 Gene

    303 amino acids
    Molecular mass:
    32580 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for NUDT22 Gene


neXtProt entry for NUDT22 Gene

Proteomics data for NUDT22 Gene at MOPED

Post-translational modifications for NUDT22 Gene

  • Ubiquitination at Lys60
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for NUDT22 Gene

Domains for NUDT22 Gene

Gene Families for NUDT22 Gene

  • NUDT :Nudix motif containing

Protein Domains for NUDT22 Gene


Suggested Antigen Peptide Sequences for NUDT22 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9BRQ3
  • Although related to the NUDIX hydrolase family, it lacks the Nudix box and does not seem to act as a hydrolase
  • Contains 1 nudix hydrolase domain.
  • Belongs to the Nudix hydrolase family.
genes like me logo Genes that share domains with NUDT22: view

Function for NUDT22 Gene

Gene Ontology (GO) - Molecular Function for NUDT22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with NUDT22: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NUDT22

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NUDT22 Gene

Localization for NUDT22 Gene

Subcellular locations from

Jensen Localization Image for NUDT22 Gene COMPARTMENTS Subcellular localization image for NUDT22 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

Gene Ontology (GO) - Cellular Components for NUDT22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with NUDT22: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for NUDT22 Gene

Pathways for NUDT22 Gene

SuperPathways for NUDT22 Gene

No Data Available

Interacting Proteins for NUDT22 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000279206 Q9BRQ3-NUD22_HUMAN for NUDT22 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for NUDT22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with NUDT22: view

No data available for Pathways by source for NUDT22 Gene

Transcripts for NUDT22 Gene

Unigene Clusters for NUDT22 Gene

Nudix (nucleoside diphosphate linked moiety X)-type motif 22:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NUDT22

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NUDT22 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8
SP1: -
SP2: - -
SP4: - -
SP5: - - - - -
SP6: - -

Relevant External Links for NUDT22 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NUDT22 Gene

mRNA expression in normal human tissues for NUDT22 Gene

Protein differential expression in normal tissues for NUDT22 Gene

This gene is overexpressed in Fetal gut (64.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for NUDT22 Gene

SOURCE GeneReport for Unigene cluster for NUDT22 Gene Hs.656074

genes like me logo Genes that share expressions with NUDT22: view

Expression partners for NUDT22 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for NUDT22 Gene

Orthologs for NUDT22 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for NUDT22 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia NUDT22 35
  • 87.93 (n)
  • 86.9 (a)
NUDT22 36
  • 87 (a)
(Canis familiaris)
Mammalia NUDT22 35
  • 86.51 (n)
  • 86.51 (a)
NUDT22 36
  • 62 (a)
(Mus musculus)
Mammalia Nudt22 35
  • 85.63 (n)
  • 85.87 (a)
Nudt22 16
Nudt22 36
  • 81 (a)
(Pan troglodytes)
Mammalia NUDT22 35
  • 99.45 (n)
  • 99.34 (a)
NUDT22 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Nudt22 35
  • 86.22 (n)
  • 85.16 (a)
(Monodelphis domestica)
Mammalia NUDT22 36
  • 71 (a)
(Anolis carolinensis)
Reptilia NUDT22 36
  • 59 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia nudt22 35
  • 55.16 (n)
  • 57.65 (a)
Str.502 35
African clawed frog
(Xenopus laevis)
Amphibia P17F11 35
(Danio rerio)
Actinopterygii nudt22 35
  • 58.3 (n)
  • 55.48 (a)
wufb64h05 35
nudt22 36
  • 46 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons NUDT9 35
  • 43.66 (n)
  • 39.55 (a)
(Oryza sativa)
Liliopsida Os05g0117500 35
  • 43.36 (n)
  • 35.37 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 38 (a)
Species with no ortholog for NUDT22:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NUDT22 Gene

Gene Tree for NUDT22 (if available)
Gene Tree for NUDT22 (if available)

Paralogs for NUDT22 Gene

No data available for Paralogs for NUDT22 Gene

Variants for NUDT22 Gene

Sequence variations from dbSNP and Humsavar for NUDT22 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs537115310 -- 64,228,268(+) ACCTT(C/T)GCCTC intron-variant
VAR_029616 -
VAR_029617 -
VAR_029618 -
VAR_050414 -

Structural Variations from Database of Genomic Variants (DGV) for NUDT22 Gene

Variant ID Type Subtype PubMed ID
dgv1156n71 CNV Loss 21882294
nsv469961 CNV Loss 18288195
dgv1163n71 CNV Loss 21882294
dgv1164n71 CNV Loss 21882294
dgv1165n71 CNV Loss 21882294
dgv1166n71 CNV Loss 21882294
nsv832186 CNV Loss 17160897
dgv1167n71 CNV Loss 21882294
esv992196 CNV Deletion 20482838
nsv897674 CNV Loss 21882294

Relevant External Links for NUDT22 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUDT22 Gene

Disorders for NUDT22 Gene

Relevant External Links for NUDT22

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for NUDT22 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for NUDT22 Gene

Publications for NUDT22 Gene

  1. Genome-wide association study of the child behavior checklist dysregulation profile. (PMID: 21784300) Mick E. … Faraone S.V. (J Am Acad Child Adolesc Psychiatry 2011) 3 48
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for NUDT22 Gene

Sources for NUDT22 Gene

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