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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NUDT18 Gene

protein-coding   GIFtS: 48
GCID: GC08M022021

Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif...

  Search for NUDT18
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 181 2     7,8-Dihydro-8-Oxoguanine Phosphatase2 3
MutT Human Homolog 31 2     MTH32 3
MutT Homolog 32 3     8-Oxo-DGDP Phosphatase NUDT182
Nucleoside Diphosphate-Linked Moiety X Motif 182 3     EC 3.6.1.583
Nudix Motif 182 3     EC 3.6.18
2-Hydroxy-DADP Phosphatase2 3     

External Ids:    HGNC: 261941   Entrez Gene: 798732   Ensembl: ENSG000001735667   UniProtKB: Q6ZVK83   

Export aliases for NUDT18 gene to outside databases

Previous GC identifer: GC08M020506


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NUDT18 Gene:
The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially
toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different
nucleotide substrates, cofactors, and signaling molecules. This protein contains a Nudix hydrolase domain and
hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates. (provided by RefSeq, Sep 2012)

GeneCards Summary for NUDT18 Gene: 
NUDT18 (nudix (nucleoside diphosphate linked moiety X)-type motif 18) is a protein-coding gene. Among its related super-pathways are Purine metabolism and Metabolic pathways. GO annotations related to this gene include 8-oxo-GDP phosphatase activity and magnesium ion binding.

UniProtKB/Swiss-Prot: NUD18_HUMAN, Q6ZVK8
Function: Mediates the hydrolyzis of oxidized nucleoside diphosphate derivatives. Hydrolyzes
8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates.
Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Hydrolyzes also 8-OH-dADP and 2-OH-dADP.
Exhibited no or minimal hydrolyzis activity against 8-oxo-dGTP, 8-oxo-GTP, dGTP, GTP, dGDP and GDP. Probably
removes oxidized guanine nucleotides from both the DNA and RNA precursor pools




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_167187.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NUDT18 gene promoter:
         AhR   C/EBPbeta   Tal-1   Egr-1   Olf-1   Nkx2-5   NF-kappaB1   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUDT18 promoter sequence
   Search SABiosciences Chromatin IP Primers for NUDT18

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUDT18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p21.3   Ensembl cytogenetic band:  8p21.3   HGNC cytogenetic band: 8p21.3

NUDT18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUDT18 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M022021:  view genomic region     (about GC identifiers)

Start:
21,964,383 bp from pter      End:
21,966,932 bp from pter
Size:
2,550 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NUD18_HUMAN, Q6ZVK8 (See protein sequence)
Recommended Name: 8-oxo-dGDP phosphatase NUDT18  
Size: 323 amino acids; 35501 Da
Cofactor: Manganese (By similarity). Magnesium
Sequence caution: Sequence=BAC85853.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for NUDT18:
3GG6 (3D)    
Secondary accessions: Q8IZ75 Q9H687
Alternative splicing: 2 isoforms:  Q6ZVK8-1   Q6ZVK8-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NUDT18: NX_Q6ZVK8

Explore proteomics data for NUDT18 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6ZVK8

  • 2 DME Specific Peptides for NUDT18 (Q6ZVK8)
     QEAKREC  WYLPAGRME 

    NUDT18 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NUDT18 Protein Expression
    REFSEQ proteins: NP_079091.3  
    ENSEMBL proteins: 
     ENSP00000430539   ENSP00000429877   ENSP00000430117   ENSP00000307852  
    Reactome Protein details: Q6ZVK8
    Human Recombinant Protein Products for NUDT18: 
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    Cloud-Clone Corp. Proteins for NUDT18 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--

    NUDT18 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    NUDT: Nudix motif containing

    4 InterPro protein domains:
     IPR015797 NUDIX_hydrolase_dom-like
     IPR020476 Nudix_hydrolase
     IPR020084 NUDIX_hydrolase_CS
     IPR000086 NUDIX_hydrolase_dom

    Graphical View of Domain Structure for InterPro Entry Q6ZVK8

    ProtoNet protein and cluster: Q6ZVK8

    1 Blocks protein domain: IPB000086 NUDIX hydrolase

    UniProtKB/Swiss-Prot: NUD18_HUMAN, Q6ZVK8
    Similarity: Belongs to the Nudix hydrolase family
    Similarity: Contains 1 nudix hydrolase domain


    NUDT18 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NUD18_HUMAN, Q6ZVK8
    Function: Mediates the hydrolyzis of oxidized nucleoside diphosphate derivatives. Hydrolyzes
    8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates.
    Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Hydrolyzes also 8-OH-dADP and 2-OH-dADP.
    Exhibited no or minimal hydrolyzis activity against 8-oxo-dGTP, 8-oxo-GTP, dGTP, GTP, dGDP and GDP. Probably
    removes oxidized guanine nucleotides from both the DNA and RNA precursor pools
    Catalytic activity: 8-oxo-dGDP + H(2)O = 8-oxo-dGMP + phosphate
    Biophysicochemical properties: Kinetic parameters: KM=10.7 uM for 8-Oxo-dGDP; KM=11.7 uM for 8-Oxo-GDP; Vmax=212
    pmol/min/ug enzyme toward 8-Oxo-dGDP (at 30 degrees Celsius); Vmax=246 pmol/min/ug enzyme toward 8-Oxo-GDP (at 30
    degrees Celsius); pH dependence: Optimum pH is 8.5;

         Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.1.581

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287magnesium ion binding IDA--
    GO:0005515protein binding IPI16189514
    GO:0016787hydrolase activity ----
    GO:00447158-oxo-dGDP phosphatase activity IDA--
    GO:00447168-oxo-GDP phosphatase activity IDA--
         
    NUDT18 for ontologies           About GeneDecksing


    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidNUDT18 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NUDT18 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Purine metabolism
    Metabolism of nucleotides0.42
    2Metabolism
    Metabolism0.40
    3Phosphate bond hydrolysis by NUDT proteins
    Phosphate bond hydrolysis by NUDT proteins

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for NUDT18
        Metabolism of nucleotides
    Metabolism
    Phosphate bond hydrolysis by NUDT proteins



    NUDT18 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUDT18

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/43 Interacting proteins for NUDT18 (Q6ZVK81, 2, 3 ENSP000003078524) via UniProtKB, MINT, STRING, and/or I2D (see all 43)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APIPQ96GX91, 2, 3, ENSP000002783594EBI-740486,EBI-359248 MINT-66886 I2D: score=5 STRING: ENSP00000278359
    DHPSP493661, 2, 3, ENSP000002100604EBI-740486,EBI-741925 MINT-66764 I2D: score=5 STRING: ENSP00000210060
    HSD17B14Q9BPX11, 2, 3, ENSP000002632784EBI-740486,EBI-742664 MINT-67936 I2D: score=5 STRING: ENSP00000263278
    PAICSP222341, 2, 3, ENSP000003825954EBI-740486,EBI-712261 MINT-68027 I2D: score=5 STRING: ENSP00000382595
    DUTP333161, 2, 3, ENSP000003703764EBI-740486,EBI-353224 MINT-68046 I2D: score=4 STRING: ENSP00000370376
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0034656nucleobase-containing small molecule catabolic process TAS--
    GO:0044281small molecule metabolic process TAS--
    GO:0046057dADP catabolic process IDA--
    GO:0046067dGDP catabolic process IDA--
    GO:0046712GDP catabolic process IDA--

    NUDT18 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NUDT18 (NUD18)

    6 HMDB Compounds for NUDT18    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    CDPCDP (see all 3)63-38-7--
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    MagnesiumMagnesium (see all 2)7439-95-4--
    Manganesemanganese 7439-96-5--
    dTDPDeoxy-tdp (see all 5)491-97-4--

    Search CenterWatch for drugs/clinical trials and news about NUDT18 / NUD18

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NUDT18 gene: 
    NM_024815.3  

    Unigene Cluster for NUDT18:

    Nudix (nucleoside diphosphate linked moiety X)-type motif 18
    Hs.745387  [show with all ESTs]
    Unigene Representative Sequence: AK124446
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000522405 ENST00000521807(uc003xar.1) ENST00000522379 ENST00000309188(uc003xaq.1)

    miRNA
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    hsa-miR-512-5p hsa-miR-124 hsa-miR-506 hsa-miR-510
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    Additional mRNA sequence: 

    AK124446.1 BC016902.1 

    3 DOTS entries:

    DT.101981596  DT.97808406  DT.75101502 

    24/61 AceView cDNA sequences (see all 61):

    CR607168 CR622192 AI669189 AL559394 NM_024815 AK026147 BM810518 AI885403 
    CA313506 BM988169 AA374925 BU684999 AK124446 BM671195 BF437150 BU180613 
    BX344375 CK299063 CF128006 BG764039 BG697422 BG764769 BF939302 BC016902 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NUDT18 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGGGGCACT
    NUDT18 Expression
    About this image


    See NUDT18 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NUDT18

    SOURCE GeneReport for Unigene cluster: Hs.745387
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NUDT18 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nudt181 , 5 nudix (nucleoside diphosphate linked moiety X)-type more1, 5 82.46(n)1
    81.42(a)1
      14 (36.32 cM)5
    2134841  NM_153136.41  NP_694776.21 
     705778475 
    lizard
    (Anolis carolinensis)
    Reptilia NUDT186
    Uncharacterized protein
    50(a)
    1 ↔ 1
    GL343858.1(67990-72195)
    zebrafish
    (Danio rerio)
    Actinopterygii nudt181 nudix (nucleoside diphosphate linked moiety X)-type more 54.29(n)
    48.49(a)
      550541  NM_001017843.1  NP_001017843.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG108981 CG10898 51.49(n)
    44.68(a)
      41384  NM_141826.3  NP_650083.1 
    worm
    (Caenorhabditis elegans)
    Secernentea ndx-16
    Putative nudix hydrolase 1
    28(a)
    1 ↔ 1
    I(12679211-12681815)


    ENSEMBL Gene Tree for NUDT18 (if available)
    TreeFam Gene Tree for NUDT18 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/165 SNPs in NUDT18 are shown (see all 165)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs573160991,2
    C--21966701(+) CAGCC-/CGCACG 2 C L fra11Minor allele frequency- C:0.00NA 2
    rs583435761,2
    C--21966708(+) ACGGG-/GCGCCG 2 C V fra11Minor allele frequency- G:0.00NA 2
    rs559658061,2
    C,F--21968887(+) TGTGTG/ATGTGT 1 -- us2k13Minor allele frequency- A:0.50NA 8
    rs343942711,2
    C--22217934(+) AAAAA-/AA/AAA
            
    AAAAA
    2 -- ds5001 cds11NA 2
    rs1832877611,2
    --22218040(+) GCCAGA/GGGGAG 1 -- ds50010--------
    rs22793541,2
    C,F,A--22218046(+) GGGAGG/TGGTCT 1 -- ds50016Minor allele frequency- T:0.43EA CSA WA NA 1666
    rs783433071,2
    C,F--22218054(+) TCTGCG/ACCAGG 1 -- ds50011Minor allele frequency- A:0.05WA 118
    rs787279771,2
    F--22218076(+) AGAGAG/ACAGAG 1 -- ds50011Minor allele frequency- A:0.02EA 120
    rs604569151,2
    C,F--22218152(+) GGGCTA/CAGAGC 1 -- ds50012Minor allele frequency- C:0.33WA CSA 3
    rs1113372941,2
    F--22218181(+) GGTCCC/TCTCAG 1 -- ds50011Minor allele frequency- T:0.50CSA 2

    HapMap Linkage Disequilibrium report for NUDT18 (21964383 - 21966932 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/15 variations for NUDT18 (see all 15):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv527293CNV Loss19592680
    dgv7758n71CNV Loss21882294
    dgv450n21CNV Loss19592680
    nsv528590CNV Loss19592680
    dgv881n27CNV Loss19166990
    nsv465613CNV Loss19166990
    dgv7756n71CNV Loss21882294
    nsv470204CNV Loss18288195
    dgv7757n71CNV Loss21882294
    nsv890654CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NUDT18 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with NUDT18)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human MTH3 (NUDT18) protein hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates: comparison with MTH1 and MTH2. (PubMed id 22556419)1, 2, 3 Takagi Y....Sekiguchi M. (2012)
    2. Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
    3. An empirical framework for binary interactome mapping . (PubMed id 19060904)1 Venkatesan K....Vidal M. (2009)
    4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    6. DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (2006)
    7. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
    8. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79873 HGNC: 26194 AceView: FLJ22494 Ensembl:ENSG00000173566 euGenes: HUgn79873
    ECgene: NUDT18 H-InvDB: NUDT18

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NUDT18 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NUDT18 gene:
    Search GeneIP for patents involving NUDT18

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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