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Aliases for NUDT17 Gene

Aliases for NUDT17 Gene

  • Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 17 2 3
  • Nudix Motif 17 4
  • EC 3.6.1.- 4

External Ids for NUDT17 Gene

Previous GeneCards Identifiers for NUDT17 Gene

  • GC01M143075
  • GC01M144297
  • GC01M145586
  • GC01M119550

Summaries for NUDT17 Gene

GeneCards Summary for NUDT17 Gene

NUDT17 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 17) is a Protein Coding gene. GO annotations related to this gene include hydrolase activity.

UniProtKB/Swiss-Prot for NUDT17 Gene

  • Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NUDT17 Gene

Genomics for NUDT17 Gene

Regulatory Elements for NUDT17 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for NUDT17 Gene

Start:
145,845,488 bp from pter
End:
145,848,953 bp from pter
Size:
3,466 bases
Orientation:
Plus strand

Genomic View for NUDT17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NUDT17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NUDT17 Gene

Proteins for NUDT17 Gene

  • Protein details for NUDT17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C025-NUD17_HUMAN
    Recommended name:
    Nucleoside diphosphate-linked moiety X motif 17
    Protein Accession:
    P0C025
    Secondary Accessions:

    Protein attributes for NUDT17 Gene

    Size:
    328 amino acids
    Molecular mass:
    35923 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
    Quaternary structure:
    No Data Available

neXtProt entry for NUDT17 Gene

Proteomics data for NUDT17 Gene at MOPED

Post-translational modifications for NUDT17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NUDT17 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NUDT17 Gene

Domains for NUDT17 Gene

Gene Families for NUDT17 Gene

HGNC:
  • NUDT :Nudix motif containing

Protein Domains for NUDT17 Gene

Suggested Antigen Peptide Sequences for NUDT17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C025

UniProtKB/Swiss-Prot:

NUD17_HUMAN :
  • P0C025
Domain:
  • Contains 1 nudix hydrolase domain.
Family:
  • Belongs to the Nudix hydrolase family.
genes like me logo Genes that share domains with NUDT17: view

Function for NUDT17 Gene

Molecular function for NUDT17 Gene

UniProtKB/Swiss-Prot Function:
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.

Enzyme Numbers (IUBMB) for NUDT17 Gene

Gene Ontology (GO) - Molecular Function for NUDT17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016787 hydrolase activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with NUDT17: view

Animal Model Products

No data available for Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NUDT17 Gene

Localization for NUDT17 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NUDT17 Gene COMPARTMENTS Subcellular localization image for NUDT17 gene
Compartment Confidence
extracellular 2
cytoskeleton 1
cytosol 1
endoplasmic reticulum 1
golgi apparatus 1
lysosome 1
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for NUDT17 Gene

Pathways for NUDT17 Gene

SuperPathways for NUDT17 Gene

No Data Available

Interacting Proteins for NUDT17 Gene

Gene Ontology (GO) - Biological Process for NUDT17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with NUDT17: view

No data available for Pathways by source for NUDT17 Gene

Compounds for NUDT17 Gene

(6) HMDB Compounds for NUDT17 Gene

Compound Synonyms Cas Number PubMed IDs
ADP
  • adenosindiphosphorsaeure
58-64-0
CDP
  • CDP
63-38-7
dTDP
  • Deoxy-tdp
491-97-4
Guanosine diphosphate
  • 5'-GDP
146-91-8
Magnesium
  • Magnesium
7439-95-4
genes like me logo Genes that share compounds with NUDT17: view

Transcripts for NUDT17 Gene

Unigene Clusters for NUDT17 Gene

Nudix (nucleoside diphosphate linked moiety X)-type motif 17:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NUDT17

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NUDT17 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6
SP1: -
SP2: - -
SP3:
SP4:

Relevant External Links for NUDT17 Gene

GeneLoc Exon Structure for
NUDT17
ECgene alternative splicing isoforms for
NUDT17

Expression for NUDT17 Gene

mRNA expression in normal human tissues for NUDT17 Gene

Protein differential expression in normal tissues for NUDT17 Gene

This gene is overexpressed in Adipocyte (32.0), Spleen (21.7), and Kidney (9.8).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for NUDT17 Gene

SOURCE GeneReport for Unigene cluster for NUDT17 Gene Hs.585066

genes like me logo Genes that share expressions with NUDT17: view

Expression partners for NUDT17 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for NUDT17 Gene

Orthologs for NUDT17 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NUDT17 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia NUDT17 35
  • 85.08 (n)
  • 81.69 (a)
NUDT17 36
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NUDT17 35
  • 85.54 (n)
  • 83.39 (a)
NUDT17 36
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nudt17 35
  • 81.36 (n)
  • 72.2 (a)
Nudt17 16
Nudt17 36
  • 66 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia NUDT17 35
  • 98.68 (n)
  • 96.65 (a)
NUDT17 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nudt17 35
  • 80.92 (n)
  • 72.76 (a)
oppossum
(Monodelphis domestica)
Mammalia NUDT17 36
  • 62 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia nudt17 35
  • 55.95 (n)
  • 50.45 (a)
zebrafish
(Danio rerio)
Actinopterygii nudt17 35
  • 52.57 (n)
  • 49.01 (a)
nudt17 36
  • 44 (a)
OneToOne
Species with no ortholog for NUDT17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NUDT17 Gene

ENSEMBL:
Gene Tree for NUDT17 (if available)
TreeFam:
Gene Tree for NUDT17 (if available)

Paralogs for NUDT17 Gene

No data available for Paralogs for NUDT17 Gene

Variants for NUDT17 Gene

Sequence variations from dbSNP and Humsavar for NUDT17 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1328581 -- 145,845,095(+) TAGGG(A/C/G/T)CAAGA upstream-variant-2KB
rs1887802 -- 145,845,402(+) AGTCA(G/T)TCGGT upstream-variant-2KB
rs1887803 -- 145,845,552(+) AACCC(C/G)GCTAC upstream-variant-2KB, utr-variant-5-prime
rs1887804 -- 145,845,577(+) TTCCG(A/T)GGGGA upstream-variant-2KB, utr-variant-5-prime
rs2004659 -- 145,846,884(+) TATTA(A/C/G/T)CAAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NUDT17 Gene

Variant ID Type Subtype PubMed ID
nsv7181 OTHER Inversion 18451855
dgv15n16 CNV Deletion 17901297
dgv46e201 CNV Deletion 23290073
esv2422428 CNV Duplication 17116639
dgv347n71 CNV Gain 21882294
nsv831370 CNV Gain 17160897
nsv831381 CNV Gain 17160897
nsv872232 CNV Gain 21882294

Relevant External Links for NUDT17 Gene

HapMap Linkage Disequilibrium report
NUDT17

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NUDT17 Gene

Disorders for NUDT17 Gene

No disorders were found for NUDT17 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for NUDT17 Gene

Publications for NUDT17 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Generation and analysis of 280,000 human expressed sequence tags. (PMID: 8889549) Hillier L.D. … Marra M. (Genome Res. 1996) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for NUDT17 Gene

Sources for NUDT17 Gene

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