NUDT17 Gene
protein-coding GIFtS: 39
GCID: GC01M145586
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nudix (nucleoside diphosphate linked moiety X)-type motif...
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Aliases
for NUDT17 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 171 2 | | Nudix Motif 172 3 | | FLJ344331 | | Nucleoside Diphosphate-Linked Moiety X Motif 172 | | EC 3.6.1.-3 |
Export aliases for NUDT17 gene to outside databasesPrevious GC identifers: GC01M143075 GC01M144297 GC01M119550 |
Summaries
for NUDT17 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: NUD17_HUMAN, P0C025Function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives (By similarity)
|
Genomic Views
for NUDT17 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167185.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NUDT17 gene promoter:
Sox5 MAZR Pax-2 Pax-2a E47 GATA-1 YY1 AREB6 S8 FOXO4
Other transcription factors
Search SABiosciences Chromatin IP Primers for NUDT17
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUDT17 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.1 Ensembl cytogenetic band: 1q21.1 HGNC cytogenetic band: 1q21.1NUDT17 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M145586: view genomic region
(about GC identifiers)
Start:
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145,586,115 bp from pter |
End:
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145,590,461 bp from pter |
Size:
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4,347 bases |
Orientation:
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minus strand |
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Proteins
for NUDT17 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NUD17_HUMAN, P0C025 (See
protein sequence)Recommended Name: Nucleoside diphosphate-linked moiety X motif 17 Size: 328 amino acids; 35923 Da
Cofactor: Magnesium or manganese (By similarity)Explore the universe of human proteins at neXtProt for NUDT17: NX_P0C025
NUDT17 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001012776.1
ENSEMBL proteins: ENSP00000334437 ENSP00000392616
Human Recombinant Protein Products:
NUDT17 Antibody Products:
Assay Products for NUDT17: |
Protein
Domains /
Families
for NUDT17 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NUDT17 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P0C025ProtoNet protein and cluster: P0C025 1 Blocks protein family: IPB000086 NUDIX hydrolase
UniProtKB/Swiss-Prot: NUD17_HUMAN, P0C025Similarity: Belongs to the Nudix hydrolase familySimilarity: Contains 1 nudix hydrolase domain |
Function
for NUDT17 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NUD17_HUMAN, P0C025Function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives (By similarity)Enzyme Number (IUBMB): EC 3.6.1.-1
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUDT17
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for NUDT17 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NUDT17 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUDT17 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016787 | hydrolase activity |
IEA | -- | | GO:0046872 | metal ion binding |
IEA | -- |
NUDT17 for ontologies About GeneDecksing
|
Pathways & Interactions
for NUDT17 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUDT17
|
Drugs & Compounds
for NUDT17 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NUDT17
6 HMDB Compounds for NUDT17 About this table
Search CenterWatch for drugs/clinical trials and news about NUDT17 / NUD17
|
Transcripts
for NUDT17 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NUDT17 gene: NM_001012758.2 Unigene Cluster for NUDT17: Nudix (nucleoside diphosphate linked moiety X)-type motif 17 Hs.585066 [show with all ESTs]Unigene Representative Sequence: BF6892826 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000334513(uc001eoe.3) ENST00000444015 ENST00000467151 ENST00000498192
ENST00000477878 ENST00000460879
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUDT17 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUDT17
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NUDT17 (NM_001012758) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NUDT17 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NUDT17 |
Additional cDNA sequence: BC046352.1 8 DOTS entries: DT.444950 DT.95297810 DT.100794447 DT.65287596 DT.100794440 DT.102841683 DT.95073200 DT.100028671 24/253 AceView cDNA sequences (see all 253): CB143033 AA582676 AA830644 BE257375 BX093964 CR592330 BQ723747 BG249142 CR605615 CD244339 BI907327 CR624046 BM916377 BM556814 BM727922 AA146669 AA280982 BU742449 BE315117 BX395308 AA906250 BM980652 AY091463 BX336126
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for NUDT17 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 |
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| SP1: | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for NUDT17
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Expression
for NUDT17 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NUDT17 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See NUDT17 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NUDT17
SOURCE GeneReport for Unigene cluster: Hs.585066
SABiosciences Custom PCR Arrays for NUDT17
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUDT17
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat NUDT17 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUDT17 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUDT17 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUDT17 |
Orthologs
for NUDT17 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for NUDT17 gene from 2/12 species (see all 12) About this table
ENSEMBL Gene Tree for NUDT17 (if available)
TreeFam Gene Tree for NUDT17 (if available) |
Paralogs
for NUDT17 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for NUDT17 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NUDT17 (145586115 - 145590461 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for NUDT17
3 CNVs: 48114 5199 53561 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUDT17 |
|
Disorders
/ Diseases
for NUDT17 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for NUDT17 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NUDT17 gene integrated from 9 sources:
(articles sorted by number of sources associating them with NUDT17) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and analysis of 280,000 human expressed sequence tags. (PubMed id 8889549)1 Hillier L.D....Marra M. (1996)
|
External Searches for NUDT17 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing NUDT17 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NUDT17 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NUDT17 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NUDT17 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for NUDT17 gene:
Search GeneIP for patents involving NUDT17
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NUDT17 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NUDT17 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NUDT17 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUDT17 | | | OriGene Protein Over-expression Lysate for NUDT17 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NUDT17 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUDT17 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUDT17 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | NUDT17 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUDT17 |
|  |  |  | | | | ThermoFisher Antibodies for NUDT17 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NUDT17 |
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