Aliases for NUDT14 Gene
External Ids for NUDT14 Gene
Previous GeneCards Identifiers for NUDT14 Gene
UDP-glucose (UDPG) acts as the sugar donor in numerous glycosylation reactions, including those involved in the production of glycogen. NUDT14 is a UDPG pyrophosphatase (EC 220.127.116.11) that hydrolyzes UDPG to produce glucose 1-phosphate and UMP (Yagi et al., 2003 [PubMed 12429023]).[supplied by OMIM, Mar 2008]
GeneCards Summary for NUDT14 Gene
NUDT14 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 14) is a Protein Coding gene. GO annotations related to this gene include ADP-ribose diphosphatase activity and UDP-sugar diphosphatase activity.
UniProtKB/Swiss-Prot for NUDT14 Gene
Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose