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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NUDT12 Gene

protein-coding   GIFtS: 56
GCID: GC05M102912

nudix (nucleoside diphosphate linked moiety X)-type motif...
 Explore 4 diseases affiliated with
NUDT12 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NUDT12    

Aliases
for NUDT12 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 121 2     DKFZP761I1721
Nucleoside Diphosphate-Linked Moiety X Motif 122 3     Nucleoside Diphosphate Linked Moiety X-Type Motif 122
Nudix Motif 122 3     Peroxisomal NADH Pyrophosphatase NUDT122
EC 3.6.1.223 8     

External Ids:    HGNC: 188261   Entrez Gene: 835942   Ensembl: ENSG000001128747   OMIM: 6092325   UniProtKB: Q9BQG23   

Export aliases for NUDT12 gene to outside databases

Previous GC identifers: GC05M102544 GC05M103315 GC05M102915 GC05M102960 GC05M098066


Summaries
for NUDT12 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for NUDT12:
Nucleotides are involved in numerous biochemical reactions and pathways within the cell as substrates, cofactors, and
effectors. Nudix hydrolases, such as NUDT12, regulate the concentrations of individual nucleotides and of nucleotide
ratios in response to changing circumstances (Abdelraheim et al., 2003 (PubMed 12790796)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: NUD12_HUMAN, Q9BQG2
Function: Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards
NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide
nucleotide cofactors required for oxidative metabolism in this organelle

Gene Wiki entry for NUDT12


Genomic Views
for NUDT12 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_034772.6  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NUDT12 gene promoter:
         TBP   Bach2   POU6F1 (c2)   LCR-F1   Cdc5   PPAR-gamma1   FOXC1   NRF-2   POU2F1c   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NUDT12 promoter sequence
   Search SABiosciences Chromatin IP Primers for NUDT12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUDT12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q21.2   Ensembl cytogenetic band:  5q21.2   HGNC cytogenetic band: 5q15

NUDT12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUDT12 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M102912:  view genomic region     (about GC identifiers)

Start:
 102,884,556 bp from pter      End:
 102,898,494 bp from pter
Size:
 13,939 bases      Orientation:
 minus strand

Proteins
for NUDT12 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NUD12_HUMAN, Q9BQG2 (See protein sequence)
Recommended Name: Peroxisomal NADH pyrophosphatase NUDT12  
Size: 462 amino acids; 52076 Da
Cofactor: Magnesium or manganese (By similarity)
Subcellular location: Peroxisome
Secondary accessions: B3KUW2 Q8TAL7

Explore the universe of human proteins at neXtProt for NUDT12: NX_Q9BQG2

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BQG2

    • 4/18 DME Specific Peptides for NUDT12 (Q9BQG2) (see all 18)
     ECENYFS  EEEDGLV  DKNEIED  KRNNSDWL 

    NUDT12 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_113626.1  
    ENSEMBL proteins: 
     ENSP00000230792   ENSP00000424521  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Novus Biologicals NUDT12 Protein
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NUDT12

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005777peroxisome IDA12790796


    NUDT12 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for NUDT12

    Protein Domains /
    Families
    for NUDT12 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NUDT12 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR015797 NUDIX_hydrolase_dom-like
     IPR002110 Ankyrin_rpt
     IPR015376 Znr_NADH_PPase
     IPR020084 NUDIX_hydrolase_CS
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q9BQG2

    ProtoNet protein and cluster: Q9BQG2

    2 Blocks protein families:
    IPB000086 NUDIX hydrolase
    IPB002110 Ankyrin repeat signature


    UniProtKB/Swiss-Prot: NUD12_HUMAN, Q9BQG2
    Similarity: Belongs to the Nudix hydrolase family. NudC subfamily
    Similarity: Contains 3 ANK repeats
    Similarity: Contains 1 nudix hydrolase domain


    Function
    for NUDT12 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NUD12_HUMAN, Q9BQG2
    Function: Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards
    NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide
    nucleotide cofactors required for oxidative metabolism in this organelle
    Catalytic activity: NAD(+) + H(2)O = AMP + NMN
    Biophysicochemical properties: Kinetic parameters: KM=11 uM for NADH; KM=16 uM for NADPH; KM=190 uM for NAD; pH
    dependence: Optimum pH is 8-9;

    Enzyme Number (IUBMB): EC 3.6.1.221 2

    miRNA
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    8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate NUDT12 (see all 21):
    hsa-miR-411* hsa-miR-607 hsa-miR-379* hsa-miR-181c hsa-miR-548a-3p hsa-miR-205* hsa-miR-181b hsa-miR-4257
    SwitchGear 3'UTR luciferase reporter plasmid: NUDT12 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUDT12 (see all 4)
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    In Situ Assay
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000210NAD+ diphosphatase activity IDA12790796
    GO:0016787hydrolase activity ----
    GO:0035529NADH pyrophosphatase activity IDA12790796
    GO:0046872metal ion binding IEA--


    NUDT12 for ontologies           About GeneDecksing


    Animal Models:
         1 MGI phenotypic allele for Nudt12 (no phenotypes)

    NUDT12 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for NUDT12 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1NAD metabolism
    		NAD metabolism1.00
    		Nicotinate and nicotinamide metabolism0.43
    		NAD metabolism1.00
    2Peroxisome
    		Peroxisome1.00
    3Nicotinate metabolism
    		NAD salvage pathway II0.18

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for NUDT12
        NAD metabolism


    1 GeneGo (Thomson Reuters) Pathway for NUDT12
        NAD metabolism

    1 BioSystems Pathway for NUDT12 
        NAD salvage pathway II


    2         Kegg Pathways  (Kegg details for NUDT12):
        Nicotinate and nicotinamide metabolism
    Peroxisome


    NUDT12 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUDT12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    5/33 Interacting proteins for NUDT12 (Q9BQG23 ENSP000002307924) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CETN3O151823I2D: score=3 
    ACOT8O147343I2D: score=1 
    DNAJA1P316893I2D: score=1 
    H2AFZP0C0S53I2D: score=1 
    IP6K3Q96PC23I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006742NADP catabolic process IDA12790796
    GO:0019677NAD catabolic process IDA12790796


    NUDT12 for ontologies           About GeneDecksing



    Drugs & Compounds
    for NUDT12 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NUDT12

    9 HMDB Compounds for NUDT12    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    MagnesiumMagnesium (see all 2)7439-95-4--
    Manganesemanganese 7439-96-5--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    Nicotinamide ribotide3-(aminocarbonyl)-1-(5-O-phosphono-b-D-ribofuranosyl)-Pyridinium hydroxide inner salt (see all 15)1094-61-7--
    Nicotinic acid adenine dinucleotideNAAD (see all 9)6450-77-7--
    Nicotinic acid mononucleotide3-Carboxy-1-beta-D-ribofuranosylpyridinium hydroxide 5'-phosphate inner salt (see all 23)321-02-8--
    WaterDihydrogen oxide (see all 2)7732-18-5--
    Search CenterWatch for drugs/clinical trials and news about NUDT12 / NUD12 

    Transcripts
    for NUDT12 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NUDT12 gene: 
    NM_031438.2  

    Unigene Cluster for NUDT12:

    Nudix (nucleoside diphosphate linked moiety X)-type motif 12
    Hs.434289  [show with all ESTs]
    Unigene Representative Sequence: NM_031438
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000230792(uc003koi.3 uc011cvb.2) ENST00000507423 ENST00000515407
    ENST00000508889(uc010jbq.1)

    miRNA
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    8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate NUDT12 (see all 21):
    hsa-miR-411* hsa-miR-607 hsa-miR-379* hsa-miR-181c hsa-miR-548a-3p hsa-miR-205* hsa-miR-181b hsa-miR-4257
    SwitchGear 3'UTR luciferase reporter plasmid: NUDT12 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NUDT12 (see all 7)
    OriGene shRNA RFP: NUDT12
    OriGene siRNA: NUDT12
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUDT12
    Clone
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    Additional cDNA sequence: 

    AK098066.1 AK304010.1 AK309942.1 AL136592.1 BC026748.1 BC041099.1 

    4 DOTS entries:

    DT.70104078  DT.423151  DT.91837033  DT.95303722 

    24/61 AceView cDNA sequences (see all 61):

    BC026748 CA411882 BX281841 CB131118 NM_031438 AI207545 AW188895 AI520819 
    CA394947 BI560422 BI850602 AI635320 BE327894 BM856229 AW361036 BU930336 
    AK098066 BG501534 BG545936 BC042967 AA329654 BC041099 BP370190 BG105388 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for NUDT12 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c · 3d · 3e ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8
    SP1:              -                       -     -                                         -               
    SP2:              -                       -     -                                                         
    SP3:              -                 -     -     -                                                         
    SP4:              -                                                                                       
    SP5:              -                                                                                       


    ECgene alternative splicing isoforms for NUDT12

    Expression
    for NUDT12 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NUDT12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAAGGAGAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See NUDT12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NUDT12

    SOURCE GeneReport for Unigene cluster: Hs.434289
        SABiosciences Custom PCR Arrays for NUDT12
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    In Situ
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    Orthologs
    for NUDT12 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for NUDT12 gene from 9/28 species (see all 28)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Nudt121 , 5 nudix (nucleoside diphosphate linked moiety X)-type more1, 5 84.13(n)1
    87.88(a)1    		   17 (30.64 cM)5
    679931  NM_026497.21  NP_080773.11 
     589996185 
    chicken
    (Gallus gallus)    		 Aves NUDT121 nudix (nucleoside diphosphate linked moiety X)-type more 75.9(n)
    75.54(a)    		   768471  XM_001231286.2  XP_001231287.1 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    		 --
    		 75(a)
    59(a)
    		 many → 1
    many → 1
    		 GL343193.1(1974189-1978341)
    GL343193.1(1986707-1991863)
    African clawed frog
    (Xenopus laevis)    		 Amphibia BJ084371.12   -- 79.47(n)    BJ084371.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii BI878334.12   -- 72.92(n)    BI878334.1 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes NPY1(YGL067W)4
    NPY11    		 NADH diphosphatase (pyrophosphatase), hydrolyzes the more4
    Npy1p1    		 46.32(n)1
    33.84(a)1    		   7(376101-377255)4
    8528131, 4  NP_011448.31  NP_011448.14 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons ATNUDT196
    		 nudix hydrolase 19
    		 26(a)
    		 1 ↔ 1
    		 5(6779854-6782482)
    rice
    (Oryza sativa)    		 Liliopsida --
    		 hydrolase, NUDIX family protein, expressed
    		 31(a)
    		 1 ↔ 1
    		 6(2156496-2159577)
    E. coli
    (Escherichia coli)    		 Gamma proteobacteria nudC6
    		 NADH pyrophosphatase
    		 25(a)
    		 1 → many
    		 Chromosome(4194926-4195699)


    ENSEMBL Gene Tree for NUDT12 (if available)
    TreeFam Gene Tree for NUDT12 (if available) 

    Paralogs
    for NUDT12 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NUDT12 gene
    NUDT132  
    1 SIMAP similar gene for NUDT12 using alignment to 2 protein entries:     NUD12_HUMAN (see all proteins):
    NUDT13

    NUDT12 for paralogs           About GeneDecksing



    Genomic Variants
    for NUDT12 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/290 NCBI SNPs in NUDT12 are shown (see all 290)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 5 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1864731871,2
    		--102884061(+) TGTTAA/TGTGGG 1 -- int10--------
    rs1156232451,2
    		C,--102884128(+) TTGTTA/TTCCTA 1 -- int10--------
    rs1827191451,2
    		--102884165(+) TAACTA/GGGTCT 1 -- int10--------
    rs1850652461,2
    		--102884209(+) AATATA/GTGGGC 1 -- int10--------
    rs1909016371,2
    		--102884306(+) TCGCTG/TTAAAC 1 -- int10--------
    rs1510743131,2
    		--102884344(+) ATATGC/TATGTA 1 -- int10--------
    rs1409894661,2
    		--102884392(+) CTTTAA/TGATTC 1 -- int10--------
    rs1698001,2
    		C,--102884487(+) AACGAT/CTGAAA 1 -- int110Minor allele frequency- C:0.27NA WA CSA EA 370
    rs1499398291,2
    		--102884578(+) ATGTAG/TTATTA 1 -- ut310--------
    rs1830911381,2
    		--102884598(+) CCAGTA/GGAATA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NUDT12 (102884556 - 102898494 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for NUDT12: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUDT12
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    Disorders / Diseases
    for NUDT12 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NUDT12 for disorders           About GeneDecksing

    OMIM gene information: 609232    OMIM disorders: --

    4 diseases for NUDT12:    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    tuberculosis    mycobacterium tuberculosis

    Human Genome Epidemiology (HuGE) Navigator: NUDT12 (2 documents)

    Export disorders for NUDT12 gene to outside databases

    Publications
    for NUDT12 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NUDT12 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with NUDT12)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Mammalian NADH diphosphatases of the Nudix family: cloning and characterization of the human peroxisomal NUDT12 protein. (PubMed id 12790796)1, 2 Abdelraheim S.R.... McLennan A.G. (2003)
    5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    6. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (2006)
    7. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
    8. From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. (PubMed id 11256614)1 Simpson J.C.... Wiemann S. (2000)

    External Searches for NUDT12 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing NUDT12 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 83594 HGNC: 18826 AceView: NUDT12 Ensembl:ENSG00000112874 euGenes: HUgn83594
    ECgene: NUDT12 Kegg: 83594 H-InvDB: NUDT12

    Other Databases showing NUDT12 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing NUDT12 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NUDT12 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NUDT12 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NUDT12 gene:
    Search GeneIP for patents involving NUDT12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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