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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NUDT10 Gene

protein-coding GIFtS: 54
GCID: GC0XP051091

nudix (nucleoside diphosphate linked moiety X)-type motif...

Explore 5 diseases affiliated with
NUDT10 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 10¹ ²		DIPP-3-Alpha¹
HDIPP3alpha¹		DIPP3-Alpha¹
APS2² ³ ⁵		HAps2¹
DIPP3a¹ ²		DIPP3A³ ⁵
Diadenosine 5',5'''-P1,P6-Hexaphosphate Hydrolase 3-Alpha² ³		Diphosphoinositol Polyphosphate Phosphohydrolase 3-Alpha²
Diadenosine Hexaphosphate Hydrolase (AMP-Forming)² ³		Diphosphoinositol Polyphosphate Phosphohydrolase Type 3 Alpha²
Nucleoside Diphosphate-Linked Moiety X Motif 10² ³		EC 3.6.1.52³
Nudix Motif 10² ³		EC 3.6.1.60³

External Ids:	HGNC: 17621¹	Entrez Gene: 170685²	Ensembl: ENSG00000122824⁷	OMIM: 300527⁵	UniProtKB: Q8NFP7³

Export aliases for NUDT10 gene to outside databases

Previous GC identifers: GC0XU990383 GC0XP049120 GC0XP049759 GC0XP049991 GC0XP050908 GC0XP048516

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NUDT10:

NUDT10 belongs to a subgroup of phosphohydrolases that preferentially attack diphosphoinositol polyphosphates (Hidaka

et al., 2002 (PubMed 12105228)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: NUD10_HUMAN, Q8NFP7

Function: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate),

suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside

oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from

Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000023.10 NC_018934.1 NT_011638.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NUDT10 gene promoter:
Nkx3-1 Nkx3-1 v4 Spz1 HSF1 (long) Nkx3-1 v1 GATA-1 Nkx3-1 v2 Nkx3-1 v3 HSF1short Ik-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): NUDT10 promoter sequence

Search SABiosciences Chromatin IP Primers for NUDT10

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUDT10

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23 Ensembl cytogenetic band: Xp11.22 HGNC cytogenetic band: Xp11.22-p11.1

NUDT10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUDT10 gene location

GeneLoc information about chromosome X GeneLoc Exon Structure

GeneLoc location for GC0XP051091: view genomic region (about GC identifiers)

Start:	51,075,083 bp from pter	End:	51,080,377 bp from pter
Size:	5,295 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NUD10_HUMAN, Q8NFP7 (See protein sequence)

Recommended Name: Diphosphoinositol polyphosphate phosphohydrolase 3-alpha

Size: 164 amino acids; 18500 Da

Cofactor: Binds 3 magnesium or manganese ions per subunit (By similarity). Manganese may be the true cofactor in vivo

Subcellular location: Cytoplasm (Probable)

1 PDB 3D structure from and Proteopedia for NUDT10:

3MCF (3D)

Secondary accessions: A8K7D7 D3DX69 Q86VK1 Q86VR0

Explore the universe of human proteins at neXtProt for NUDT10: NX_Q8NFP7

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8NFP7

NUDT10 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_694853.1

ENSEMBL proteins:

ENSP00000365174 ENSP00000348831

Reactome Protein details: Q8NFP7
Human Recombinant Protein Products:

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	Uscn Proteins for NUDT10

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--

NUDT10 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NUDT10 for domains About GeneDecksing

3 InterPro domains/families:

IPR015797 NUDIX_hydrolase_dom-like

IPR020084 NUDIX_hydrolase_CS

IPR000086 NUDIX_hydrolase_dom

Graphical View of Domain Structure for InterPro Entry Q8NFP7

ProtoNet protein and cluster: Q8NFP7

1 Blocks protein family: IPB000086 NUDIX hydrolase

UniProtKB/Swiss-Prot: NUD10_HUMAN, Q8NFP7

Similarity: Belongs to the Nudix hydrolase family. DIPP subfamily

Similarity: Contains 1 nudix hydrolase domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: NUD10_HUMAN, Q8NFP7

Function: Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate),

suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside

oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from

Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate

Catalytic activity: Diphospho-myo-inositol polyphosphate + H(2)O = myo-inositol polyphosphate + phosphate

Catalytic activity: P(1),P(6)-bis(5'-adenosyl)hexaphosphate + H(2)O = adenosine 5'-pentaphosphate + AMP

Catalytic activity: P(1),P(5)-bis(5'-adenosyl)pentaphosphate + H(2)O = adenosine 5'-tetraphosphate + AMP

Biophysicochemical properties: Kinetic parameters: KM=0.088 uM for PP-InsP5; KM=19 uM for Ap6A; KM=50 uM for Ap5A; pH

dependence: Optimum pH is 8.5;

Enzyme Numbers (IUBMB): EC 3.6.1.60¹ EC 3.6.1.52¹

miRNA Products:		OriGene 3'-UTR Clone: NUDT10 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NUDT10
		8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate NUDT10 (see all 33):
		hsa-miR-3146 hsa-let-7a-2* hsa-miR-219-5p hsa-miR-301a hsa-miR-342-3p hsa-miR-764 hsa-miR-218 hsa-miR-1276

		SwitchGear 3'UTR luciferase reporter plasmid: NUDT10 3' UTR sequence

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Gene Editing
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DNA2.0 Custom Protein Engineering Service for NUDT10

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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUDT10

Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity	ISS	--
GO:0046872	metal ion binding	IEA	--
GO:0052840	inositol diphosphate tetrakisphosphate diphosphatase activity	IEA	--
GO:0052843	inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity	IEA	--
GO:0052844	inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity	IEA	--

NUDT10 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Metabolism

Metabolism

1.00

Synthesis of IP3 and IP4 in the cytosol

Inositol phosphate metabolism

0.57

inositol pyrophosphates biosynthesis

Synthesis of pyrophosphates in the cytosol

0.42

Pathway sources
See GeneCards unified pathways
Show all pathways

3 Reactome Pathways for NUDT10

	Metabolism
	Synthesis of pyrophosphates in the cytosol
	Inositol phosphate metabolism

NUDT10 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NUDT10

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for NUDT10 (Q8NFP7^{2, 3} ENSP00000348831⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RASSF1	Q9NS23²^,³, ENSP00000349547⁴	MINT-65627 I2D: score=3 STRING: ENSP00000349547

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NUDT10

3 HMDB Compounds for NUDT10 About this table

Compound	Synonyms	CAS #	PubMed Ids
Diadenosine hexaphosphate	Adenosine 5'-(heptahydrogen hexaphosphate) P->5'-ester with adenosine (see all 9)	56983-23-4	--
Magnesium	Magnesium (see all 2)	7439-95-4	--
Manganese	manganese	7439-96-5	--

Search CenterWatch for drugs/clinical trials and news about NUDT10 / NUD10

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NUDT10 gene:

NM_153183.2

Unigene Cluster for NUDT10:

Nudix (nucleoside diphosphate linked moiety X)-type motif 10

Hs.375178 [show with all ESTs]

Unigene Representative Sequence: AF469196

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000376006(uc004dph.3) ENST00000356450(uc004dpi.4)

miRNA Products:		OriGene 3'-UTR Clone: NUDT10 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NUDT10
		8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate NUDT10 (see all 33):
		hsa-miR-3146 hsa-let-7a-2* hsa-miR-219-5p hsa-miR-301a hsa-miR-342-3p hsa-miR-764 hsa-miR-218 hsa-miR-1276

		SwitchGear 3'UTR luciferase reporter plasmid: NUDT10 3' UTR sequence

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		GenScript: all cDNA clones in your preferred vector: NUDT10 (NM_153183)
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUDT10

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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUDT10
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUDT10

Additional cDNA sequence:

AF469196.1 AK291952.1 BC049383.1 BC050700.1

5 DOTS entries:

DT.212184 DT.95164464 DT.97773825 DT.310582 DT.100831069

24/44 AceView cDNA sequences (see all 44):

AI333197 BC050700 F02214 BI752101 AL045306 F08892 AA400002 AA401433

AA044168 BI597752 BG772465 AF469196 BX449264 AI191898 AW104957 BX461575

BM546876 BX092714 F02965 BX449265 AA861744 Z43657 BQ438669 BC049383

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NUDT10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACCTAGTTTC

About this image

NUDT10 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Line H9 (WA09) (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See NUDT10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NUDT10

SOURCE GeneReport for Unigene cluster: Hs.375178

UniProtKB/Swiss-Prot: NUD10_HUMAN, Q8NFP7

Tissue specificity: Mainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is widely

expressed

SABiosciences Custom PCR Arrays for NUDT10

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for NUDT10 gene from 7/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	NUDT4⁶	Uncharacterized protein	80(a)	1 → many	1(46703880-46724579)
lizard (Anolis carolinensis)	Reptilia	NUDT4⁶	--	81(a)	1 → many	5(31478853-31493709)
zebrafish (Danio rerio)	Actinopterygii	nudt4b⁶ nudt4a⁶	nudix (nucleoside diphosphate linked moiety X)-typ... nudix (nucleoside diphosphate linked moiety X)-typ...	71(a) 58(a)	many ↔ many many ↔ many	4(1648879-1662251) 18(15474824-15516418)
fruit fly (Drosophila melanogaster)	Insecta	Aps⁶	Aps	51(a)	1 → many	3L(10887876-10892223)
worm (Caenorhabditis elegans)	Secernentea	Y92H12BL.5⁶	--	36(a)	1 → many	I(1365311-1375885)
thale cress (Arabidopsis thaliana)	eudicotyledons	NUDT18⁶ atnudt17⁶ (see all 7)	nudix hydrolase 17 (see all 7)	26(a) 25(a) (see all 7)	many ↔ many many ↔ many (see all 7)	1(5124742-5126151) 2(296510-298101)
rice (Oryza sativa)	Liliopsida	-- -- (see all 7)	hydrolase, NUDIX family, domain containing protein... hydrolase, NUDIX family, domain containing protein... (see all 7)	26(a) 25(a) (see all 7)	many ↔ many many ↔ many (see all 7)	2(30619799-30621022) 6(8067592-8069045)

ENSEMBL Gene Tree for NUDT10 (if available)
TreeFam Gene Tree for NUDT10 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for NUDT10 gene

NUDT4² NUDT11² NUDT3²

3 SIMAP similar genes for NUDT10 using alignment to 1 protein entry: NUD10_HUMAN:

NUDT11 NUDT4 NUDT3

NUDT10 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr X pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs150955484^1,2	C,	--	51073163(+)	`AAGAGC/TGAAAA`	1	--	us2k¹		0	--	--	--	--
rs1151713^1,2	C,F,A,H,	--	51073275(+)	`CCAGAA/GACAAT`	1	--	us2k¹		19		NA EA NS WA CSA	2148
rs192940456^1,2		--	51073335(+)	`TGTAAC/TAATCT`	1	--	us2k¹		0	--	--	--	--
rs185049375^1,2		--	51073396(+)	`AAATAC/TGCAAA`	1	--	us2k¹		0	--	--	--	--
rs188760616^1,2		--	51073457(+)	`AAAAGC/TCTTAG`	1	--	us2k¹		0	--	--	--	--
rs1985464^1,2	C,F,H,	--	51073483(-)	`ATAATA/GTAGTA`	1	--	us2k¹		8		NS EA NA	838
rs55854208^1,2	C,	--	51073665(+)	`GGTGGC/TAGAAG`	1	--	us2k¹		0	--	--	--	--
rs192468997^1,2		--	51073770(+)	`ACTATC/TACACA`	1	--	us2k¹		0	--	--	--	--
rs185073294^1,2		--	51073787(+)	`ACCAAA/GCCATG`	1	--	us2k¹		0	--	--	--	--
rs188268915^1,2		--	51074007(+)	`GTTTCA/GGTCTG`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for NUDT10 (51075083 - 51080377 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NUDT10: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUDT10

DNA2.0 Custom Variant and Variant Library Synthesis for NUDT10

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NUDT10 for disorders           About GeneDecksing

OMIM gene information: 300527    OMIM disorders: --

5 diseases for NUDT10:    About MalaCards

hypersensitivity reaction type ii disease addison's disease candidiasis prostate cancer

prostatitis

3 diseases from the University of Copenhagen DISEASES database for NUDT10:

Addison's disease Candidiasis Hypersensitivity reaction type II disease

Human Genome Epidemiology (HuGE) Navigator: NUDT10 (4 documents)

Export disorders for NUDT10 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for NUDT10 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with NUDT10)

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An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase. (PubMed id 12105228)^{1, 2, 3, 9} Hidaka K.... Shears S.B. (2002)
Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases. (PubMed id 12121577)^{1, 2, 9} Leslie N.R.... Safrany S.T. (2002)
The DNA sequence of the human X chromosome. (PubMed id 15772651)^{1, 2} Ross M.T.... Bentley D.R. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate. (PubMed id 12370170)^{1, 2} Fisher D.I.... Cartwright J.L. (2002)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Validation of Genome-Wide Prostate Cancer Association s in Men of African Descent. (PubMed id 21071540)¹ Chang B.L....Rebbeck T.R. (2010)
Prostate cancer risk-associated variants reported fro m genome-wide association studies: meta-analysis and their contribution to gene tic Variation. (PubMed id 20564319)¹ Kim S.T....Sun J. (2010)
Multiple newly identified loci associated with prostate cancer susceptibility. (PubMed id 18264097)¹ Eeles R.A....Easton D.F. (2008)
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. (PubMed id 18264098)¹ Gudmundsson J.... Stefansson K. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 170685	HGNC: 17621	AceView: NUDT10	Ensembl:ENSG00000122824	euGenes: HUgn170685
ECgene: NUDT10	H-InvDB: NUDT10

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for NUDT10	Pharmacogenomics, SNPs, Pathways

Intellectual Property for NUDT10 gene
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