Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NUDCD1 Gene

protein-coding GIFtS: 45
GCID: GC08M110323

NudC domain containing 1

Explore 1 disease affiliated with
NUDCD1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
NudC Domain Containing 1¹ ²		FLJ14991¹
CML66¹ ² ³ ⁵		OVA66²
Chronic Myelogenous Leukemia Tumor Antigen 66² ³		NudC Domain-Containing Protein 1²
Tumor Antigen CML66² ³

External Ids:	HGNC: 24306¹	Entrez Gene: 84955²	Ensembl: ENSG00000120526⁷	OMIM: 606109⁵	UniProtKB: Q96RS6³

Export aliases for NUDCD1 gene to outside databases

Previous GC identifer: GC08M105575

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000008.10 NC_018919.1 NT_008046.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NUDCD1 gene promoter:
HOXA9B HOXA9 ISGF-3 Sp1 Nkx6-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NUDCD1 promoter sequence

Search SABiosciences Chromatin IP Primers for NUDCD1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUDCD1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q23 Ensembl cytogenetic band: 8q23.1 HGNC cytogenetic band: 8q23

NUDCD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUDCD1 gene location

GeneLoc information about chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M110323: view genomic region (about GC identifiers)

Start:	110,253,148 bp from pter	End:	110,346,614 bp from pter
Size:	93,467 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NUDC1_HUMAN, Q96RS6 (See protein sequence)

Recommended Name: NudC domain-containing protein 1

Size: 583 amino acids; 66756 Da

Subcellular location: Isoform 1: Cytoplasm. Nucleus

Subcellular location: Isoform 2: Cytoplasm

Subcellular location: Isoform 3: Cytoplasm. Nucleus

Miscellaneous: Isoform 1 is the dominant immunogenic isoform and is capable of eliciting a humoral response in

individuals with a variety of solid tumors. Expression of isoform 1 in a wide variety of malignancies as well as the

presence of an immunogenic epitope suggest that it may be a suitable target for antigen-specific immunotherapy

Secondary accessions: B4DVX6 Q4G130 Q8NDQ5 Q8NG18 Q96SI4 Q9BVR5

Alternative splicing: 3 isoforms: Q96RS6-1 Q96RS6-2 Q96RS6-3 (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for NUDCD1: NX_Q96RS6

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96RS6

NUDCD1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001121683.1 NP_116258.2

ENSEMBL proteins:

ENSP00000239690 ENSP00000410707 ENSP00000430095 ENSP00000430859

Human Recombinant Protein Products for NUDCD1:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: NUDCD1 OriGene Custom Protein Services for NUDCD1
	GenScript Custom Purified and Recombinant Proteins Services for NUDCD1
	Novus Biologicals NUDCD1 Protein Novus Biologicals NUDCD1 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for NUDCD1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005737	cytoplasm	IEA	--

NUDCD1 for ontologies About GeneDecksing

NUDCD1 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for NUDCD1
	GenScript Custom Superior Antibodies Services for NUDCD1
	Novus Biologicals NUDCD1 Antibodies
	Abcam antibodies for NUDCD1
	Uscn Antibodies for NUDCD1
	Search ThermoFisher Antibodies for NUDCD1

Assay Products for NUDCD1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for NUDCD1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for NUDCD1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NUDCD1 for domains About GeneDecksing

3 InterPro domains/families:

IPR008978 HSP20-like_chaperone

IPR017447 CS_domain

IPR007052 CS-like_domain

Graphical View of Domain Structure for InterPro Entry Q96RS6

ProtoNet protein and cluster: Q96RS6

UniProtKB/Swiss-Prot: NUDC1_HUMAN, Q96RS6

Similarity: Contains 1 CS domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for NUDCD1

miRNA Products:		OriGene 3'-UTR Clone (see all 2): NUDCD1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NUDCD1
		8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate NUDCD1 (see all 13):
		hsa-miR-3163 hsa-miR-2110 hsa-miR-200a hsa-miR-216b hsa-miR-181a-2* hsa-miR-4282 hsa-miR-141 hsa-miR-144

		SwitchGear 3'UTR luciferase reporter plasmid: NUDCD1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NUDCD1 (see all 7) OriGene shRNA RFP: NUDCD1 OriGene siRNA: NUDCD1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUDCD1
		Sirion Biotech Custom design and validation of potent shRNA sequences against NUDCD1

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for NUDCD1
			Sirion Biotech Customized adenovirus for overexpression of NUDCD1 Sirion Biotech Customized adenovirus for potent knockdown of NUDCD1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUDCD1 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUDCD1 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): NUDCD1 (NM_001128211)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NUDCD1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUDCD1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for NUDCD1
		Search LifeMap BioReagents cell lines for NUDCD1
		Sirion Biotech Customized stable knockdown cell line services for NUDCD1 Sirion Biotech Customized inducible knockdown cell line services for NUDCD1 Sirion Biotech Customized stable overexpressing cell line services for NUDCD1 Sirion Biotech Customized inducible overexpressing cell line services for NUDCD1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUDCD1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NUDCD1

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for NUDCD1 (Q96RS6³ ENSP00000239690⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
USP36	Q9P275³, ENSP00000310590⁴	I2D: score=2 STRING: ENSP00000310590
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NUDCD1
Search CenterWatch for drugs/clinical trials and news about NUDCD1 / NUDC1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NUDCD1 gene (2 alternative transcripts):

NM_001128211.1 NM_032869.3

Unigene Cluster for NUDCD1:

NudC domain containing 1

Hs.380291 [show with all ESTs]

Unigene Representative Sequence: NM_032869

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000239690(uc003yna.3 uc003ynb.4 uc010mcl.3) ENST00000427660(uc010mcm.1)

ENST00000519607 ENST00000521439

miRNA Products:		OriGene 3'-UTR Clone (see all 2): NUDCD1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NUDCD1
		8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate NUDCD1 (see all 13):
		hsa-miR-3163 hsa-miR-2110 hsa-miR-200a hsa-miR-216b hsa-miR-181a-2* hsa-miR-4282 hsa-miR-141 hsa-miR-144

		SwitchGear 3'UTR luciferase reporter plasmid: NUDCD1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NUDCD1 (see all 7) OriGene shRNA RFP: NUDCD1 OriGene siRNA: NUDCD1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUDCD1
		Sirion Biotech Custom design and validation of potent shRNA sequences against NUDCD1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUDCD1 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUDCD1 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): NUDCD1 (NM_001128211)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NUDCD1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUDCD1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUDCD1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat NUDCD1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUDCD1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUDCD1

Additional cDNA sequence:

AF283301.1 AF283302.1 AF521133.1 AK027897.1 AK301278.1 AK307663.1 AK311583.1 AK315006.1

AL832317.1 BC000967.2 BC031258.1 BC043406.1

8 DOTS entries:

DT.101972324 DT.451680 DT.95079998 DT.95171777 DT.100782694 DT.317452 DT.121470153 DT.100782695

24/153 AceView cDNA sequences (see all 153):

BM548201 CR603601 BM551230 AI867747 CB243935 BQ232743 CR613260 BM790249

BM828661 CA448077 BM787819 AI921332 AA352036 BM911883 AA766486 AI051750

AI057256 BM839990 N42671 AI075763 AA569843 AI587089 CA428565 CR618397

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for NUDCD1 About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12
SP1:					-
SP2:					-				-
SP3:									-

ECgene alternative splicing isoforms for NUDCD1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NUDCD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTTATATGA

About this image
See NUDCD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NUDCD1

SOURCE GeneReport for Unigene cluster: Hs.380291

UniProtKB/Swiss-Prot: NUDC1_HUMAN, Q96RS6

Tissue specificity: Isoform 1 is specifically expressed in leukemias and a variety of solid tumor cell lines and is

also detected in testis and heart. Isoform 2 is predominantly expressed in testis and weakly expressed in tumor cells

SABiosciences Custom PCR Arrays for NUDCD1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUDCD1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat NUDCD1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUDCD1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUDCD1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUDCD1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for NUDCD1 gene from 7/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Nudcd1^{1 , 5}	NudC domain containing 1^{1, 5}	89.18(n)¹ 90.33(a)¹		15 (16.91 cM)⁵ 67429¹ NM_001113554.1¹ NP_001107026.1¹ 44375227⁵
chicken (Gallus gallus)	Aves	LOC428379¹	nudC domain-containing protein 1-like	75.3(n) 75.99(a)		428379 XM_003640849.1 XP_003640897.1
lizard (Anolis carolinensis)	Reptilia	NUDCD1⁶	--	74(a)	1 ↔ 1	4(10771934-10822966)
African clawed frog (Xenopus laevis)	Amphibia	cml66-prov²	chronic myelogenous leukemia tumor antigen 66	78.56(n)		BC056062.1
zebrafish (Danio rerio)	Actinopterygii	wufc11c02²	Transcribed sequence with weak similarity to protein more	73.29(n)		BI979267.1
fruit fly (Drosophila melanogaster)	Insecta	CG10347¹	CG10347	40.78(n) 27.47(a)		32141 NM_167310.1 NP_727572.1
worm (Caenorhabditis elegans)	Secernentea	C44E4.5¹	Protein C44E4.5	42.28(n) 27.41(a)		172067 NM_059005.4 NP_491406.2

ENSEMBL Gene Tree for NUDCD1 (if available)
TreeFam Gene Tree for NUDCD1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 8 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs76179693^1,2	C	--	110252736(+)	`TTCCTG/CTGTAA`	2	--	int¹		2		NA	122
rs79208352^1,2	C	--	110252868(+)	`TCTTTT/CTTCTA`	2	--	int¹		2		NA	122
rs138093495^1,2		--	110252925(+)	`CCAAGC/GTTCTA`	2	--	int¹		0	--	--	--	--
rs79451500^1,2	F	--	110253065(+)	`TATCCT/CTAATA`	2	--	int¹		1		NA	8
rs182760495^1,2		--	110253146(+)	`CTTAAC/TATGCA`	2	--	spd¹		0	--	--	--	--
rs76754364^1,2	C	--	110253241(+)	`AGGTAC/TTATAT`	2	--	ut3¹		2		CSA WA	119
rs141798255^1,2		--	110253302(+)	`AACATC/TGTTTA`	2	--	ut3¹		0	--	--	--	--
rs150134278^1,2		--	110253396(+)	`ACATGC/TGACAA`	2	--	ut3¹		0	--	--	--	--
rs77961444^1,2	C,F	--	110253498(+)	`CAATAT/CATACA`	2	--	ut3¹		1		WA	118
rs60584579^1,2	C	--	110253558(+)	`TTCCCT/CAAGAG`	2	--	ut3¹		2		WA	120

HapMap Linkage Disequilibrium report for NUDCD1 (110253148 - 110346614 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for NUDCD1
2 CNVs: 52345 36736

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUDCD1

DNA2.0 Custom Variant and Variant Library Synthesis for NUDCD1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NUDCD1 for disorders           About GeneDecksing

OMIM gene information: 606109    OMIM disorders: --

1 disease for NUDCD1:    About MalaCards

leukemia

Export disorders for NUDCD1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for NUDCD1 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with NUDCD1)

Utopia: connect your pdf to the dynamic
world of online information

CML66, a broadly immunogenic tumor antigen, elicits a humoral immune response associated with remission of chronic myelogenous leukemia. (PubMed id 11416219)^{1, 2, 3} Yang X.-F.... Ritz J. (2001)
A novel mechanism of alternative promoter and splicing regulates the epitope generation of tumor antigen CML66-L. (PubMed id 14688378)^{1, 2} Yan Y.... Yang X.-F. (2004)
Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization. (PubMed id 22002106)² Ahmad Y.... Lamond A.I. (2012)
A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)¹ Kristensen A.R....Foster L.J. (2012)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)¹ Sowa M.E....Harper J.W. (2009)
Humoral immune responses against tumor-associated antigen OVA66 originally defined by serological analysis of recombinant cDNA expression libraries and its potentiality in cellular immunity. (PubMed id 18754882)¹ Jin S....Ge H.L. (2008)
RNA interference targeting CML66, a novel tumor antigen, inhibits proliferation, invasion and metastasis of HeLa cells. (PubMed id 18534745)¹ Wang Q....Ge H. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 84955	HGNC: 24306	AceView: CML66	Ensembl:ENSG00000120526	euGenes: HUgn84955
ECgene: NUDCD1	H-InvDB: NUDCD1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for NUDCD1	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for NUDCD1	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for NUDCD1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for NUDCD1 gene:
Search GeneIP for patents involving NUDCD1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for NUDCD1
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NUDCD1		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUDCD1
	OriGene Protein Over-expression Lysate for NUDCD1		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for NUDCD1		OriGene 3'-UTR Clone for NUDCD1
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUDCD1		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUDCD1
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for NUDCD1		OriGene Custom Protein Services for NUDCD1
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NUDCD1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUDCD1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUDCD1
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUDCD1
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUDCD1
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUDCD1

	GenScript Custom Purified and Recombinant Proteins Services for NUDCD1		GenScript cDNA clones with any tag delivered in your preferred vector for NUDCD1
	GenScript Custom Assay Services for NUDCD1		GenScript Custom Superior Antibodies Services for NUDCD1
	GenScript Custom overexpressing Cell Line Services for NUDCD1		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in NUDCD1 promoter
	Search Chromatin IP Primers for NUDCD1
	RT² qPCR Primer Assay in human, mouse, rat NUDCD1
	Search GNC Networks for NUDCD1
	SABiosciences Custom PCR Arrays for NUDCD1

Search Tocris compounds for NUDCD1

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	NUDCD1 antibodies
	NUDCD1 proteins
	NUDCD1 lysates

	Antibodies for NUDCD1
	See all of Abcam's Antibodies, Kits and Proteins for NUDCD1
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

NUDCD1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for NUDCD1

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUDCD1

	SwitchGear 3'UTR luciferase reporter plasmids for NUDCD1
	SwitchGear Promoter luciferase reporter plasmids for NUDCD1

Search ThermoFisher Antibodies for NUDCD1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUDCD1

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for NUDCD1

Sirion Biotech Customized:

	stable knockdown cell line services for NUDCD1
	inducible knockdown cell line services for NUDCD1
	design and validation of potent shRNA sequences against NUDCD1
	adenovirus for potent knockdown of NUDCD1
	adenovirus for overexpression of NUDCD1
	stable overexpressing cell line services for NUDCD1
	inducible overexpressing cell line services for NUDCD1

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes NUDCD1 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

NUDCD1 Gene

NudC domain containing 1

Aliases
for NUDCD1 gene

Summaries
for NUDCD1 gene

Genomic Views
for NUDCD1 gene

Proteins
for NUDCD1 gene

Protein Domains /
Families
for NUDCD1 gene

Function
for NUDCD1 gene

Pathways & Interactions
for NUDCD1 gene

Drugs & Compounds
for NUDCD1 gene

Transcripts
for NUDCD1 gene

Expression
for NUDCD1 gene

Orthologs
for NUDCD1 gene

Paralogs
for NUDCD1 gene

Genomic Variants
for NUDCD1 gene

Disorders / Diseases
for NUDCD1 gene

Publications
for NUDCD1 gene

External Searches for NUDCD1 gene

Genome Databases showing NUDCD1 gene

Other Databases showing NUDCD1 gene

Specialized Databases showing NUDCD1 gene

Intellectual Property
for NUDCD1 gene

Products
for NUDCD1 gene

View Random Gene

Advanced Search

Export list of displayed genes

NUDCD1 Gene

NudC domain containing 1

Aliasesfor NUDCD1 gene

Summariesfor NUDCD1 gene

Genomic Viewsfor NUDCD1 gene

Proteinsfor NUDCD1 gene

Protein Domains /Familiesfor NUDCD1 gene

Functionfor NUDCD1 gene

Pathways & Interactionsfor NUDCD1 gene

Drugs & Compoundsfor NUDCD1 gene

Transcriptsfor NUDCD1 gene

Expression for NUDCD1 gene

Orthologsfor NUDCD1 gene

Paralogsfor NUDCD1 gene

Genomic Variantsfor NUDCD1 gene

Disorders / Diseasesfor NUDCD1 gene

Publicationsfor NUDCD1 gene

External Searches for NUDCD1 gene

Genome Databases showing NUDCD1 gene

Other Databases showing NUDCD1 gene

Specialized Databases showing NUDCD1 gene

Intellectual Propertyfor NUDCD1 gene

Productsfor NUDCD1 gene

View Random Gene

Aliases
for NUDCD1 gene

Summaries
for NUDCD1 gene

Genomic Views
for NUDCD1 gene

Proteins
for NUDCD1 gene

Protein Domains /
Families
for NUDCD1 gene

Function
for NUDCD1 gene

Pathways & Interactions
for NUDCD1 gene

Drugs & Compounds
for NUDCD1 gene

Transcripts
for NUDCD1 gene

Expression
for NUDCD1 gene

Orthologs
for NUDCD1 gene

Paralogs
for NUDCD1 gene

Genomic Variants
for NUDCD1 gene

Disorders / Diseases
for NUDCD1 gene

Publications
for NUDCD1 gene

Intellectual Property
for NUDCD1 gene

Products
for NUDCD1 gene