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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NUDC Gene

protein-coding   GIFtS: 60
GCID: GC01P027226

nuclear distribution C homolog (A. nidulans)

(Previous names: nuclear distribution gene C (A.nidulans) homolog, nuclear...)
 Explore 9 diseases affiliated with
NUDC via our new
 Human Malady Compendium 
Biological research products
for NUDC
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Nuclear Distribution C Homolog (A. Nidulans)1 2     HNUDC2
Nuclear Distribution Protein C Homolog2 3     MNUDC2
NudC1     NPD0112
Nuclear Distribution Gene C (A.Nidulans) Homolog1     Nuclear Distribution Gene C Homolog2
Nuclear Distribution Gene C Homolog (A. Nidulans)1     Nuclear Migration Protein NudC2

External Ids:    HGNC: 80451   Entrez Gene: 107262   Ensembl: ENSG000000902737   OMIM: 6103255   UniProtKB: Q9Y2663   

Export aliases for NUDC gene to outside databases

Previous GC identifers: GC01M028319 GC01P026280 GC01P026481 GC01P026852 GC01P026932 GC01P027120 GC01P025501


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NUDC:
This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded
protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis.
Pseudogenes of this gene are found on chromosome 2. (provided by RefSeq, Feb 2012)

UniProtKB/Swiss-Prot: NUDC_HUMAN, Q9Y266
Function: Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of
mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation

Gene Wiki entry for NUDC


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004610.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NUDC gene promoter:
         AhR   Lmo2   Arnt   C/EBPalpha   CHOP-10   PPAR-gamma1   STAT3   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUDC promoter sequence
   Search SABiosciences Chromatin IP Primers for NUDC

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUDC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35-p34   Ensembl cytogenetic band:  1p36.11   HGNC cytogenetic band: 1p35-p34

NUDC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUDC gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P027226:  view genomic region     (about GC identifiers)

Start:
27,226,729 bp from pter      End:
27,273,353 bp from pter
Size:
46,625 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NUDC_HUMAN, Q9Y266 (See protein sequence)
Recommended Name: Nuclear migration protein nudC  
Size: 331 amino acids; 38243 Da
Subunit: Binds PLK1. Binds PAFAH1B1 (By similarity). Part of a complex containing PLK1, NUDC, dynein and dynactin
Subcellular location: Cytoplasm, cytoskeleton. Nucleus. Note=In a filamentous pattern adjacent to the nucleus of
migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center.
Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern
Sequence caution: Sequence=BAA76628.1; Type=Frameshift; Positions=140, 231, 273; Sequence=CAI13560.1; Type=Erroneous
gene model prediction; Sequence=CAI13563.1; Type=Erroneous gene model prediction;
1 PDB 3D structure from and Proteopedia for NUDC:
3QOR (3D)    
Secondary accessions: Q5QP31 Q5QP35 Q9H0N2 Q9Y2B6

Explore the universe of human proteins at neXtProt for NUDC: NX_Q9Y266

Post-translational modifications:

  • Reversibly phosphorylated on serine residues during the M phase of the cell cycle. Phosphorylation on Ser-274 and
  • Ser-326 is necessary for correct formation of mitotic spindles and chromosome separation during mitosis.
    Phosphorylated by PLK and other kinases1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y266

  • NUDC Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006591.1  
    ENSEMBL proteins: 
     ENSP00000404020   ENSP00000319664   ENSP00000400981  
    Reactome Protein details: Q9Y266
    Human Recombinant Protein Products: 
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    Uscn Proteins for NUDC

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm TAS--
    GO:0005737cytoplasm IDA--
    GO:0005794Golgi apparatus ----
    GO:0005829cytosol TAS--
    GO:0005874microtubule IEA--


    NUDC for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    NUDC for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR008978 HSP20-like_chaperone
     IPR017447 CS_domain
     IPR007052 CS-like_domain
     IPR025934 NudC_N_dom

    Graphical View of Domain Structure for InterPro Entry Q9Y266

    ProtoNet protein and cluster: Q9Y266

    1 Blocks protein family: IPB007052 CS domain

    UniProtKB/Swiss-Prot: NUDC_HUMAN, Q9Y266
    Similarity: Belongs to the nudC family
    Similarity: Contains 1 CS domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: NUDC_HUMAN, Q9Y266
    Function: Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of
    mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation
    Induction: Up-regulated in actively dividing hematopoietic precursor cells. Up-regulated in cultured erythroleukemia
    TF-1 cells by granulocyte-macrophage colony-stimulating factor. Strongly down-regulated during maturation of erythroid
    precursor cells

         Genatlas biochemistry entry for NUDC:
    nuclear distribution gene C,Aspergillus nidulans and mouse ortholog,widely expressed in fetal and adult
    tissues,coexpressed with LIS1 (PAFAH1B1) in the ventricular zone of developping brain,putatively involved in neuronal
    migration

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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----


    NUDC for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1M Phase
    M Phase1.00
    Mitotic Anaphase0.85
    Mitotic M-M/G1 phases0.88
    Separation of Sister Chromatids0.80
    Mitotic Metaphase and Anaphase0.85
    2Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion1.00
    Mitotic Prometaphase0.93
    Kinetochore assembly0.96
    3Cell Cycle
    Cell Cycle1.00
    Cell Cycle, Mitotic0.84
    4PLK1 signaling events
    PLK1 signaling events1.00
    5Lissencephaly gene (LIS1) in neuronal migration and development
    Lissencephaly gene (LIS1) in neuronal migration and development1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2 BioSystems Pathways for NUDC 
        Lissencephaly gene (LIS1) in neuronal migration and development
    PLK1 signaling events

    5/11        Reactome Pathways for NUDC (see all 11)
        Mitotic Metaphase and Anaphase
    Mitotic Prometaphase
    Resolution of Sister Chromatid Cohesion
    Mitotic Anaphase
    Mitotic Telophase/Cytokinesis



    NUDC for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NUDC

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/829 Interacting proteins for NUDC (Q9Y2661, 2, 3 ENSP000003196644) via UniProtKB, MINT, STRING, and/or I2D (see all 829)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PLK1P533502, 3, ENSP000003000934MINT-7945693 MINT-7947479 I2D: score=3 STRING: ENSP00000300093
    DYNC1H1Q142042, 3MINT-7945693 MINT-7947479 I2D: score=1 
    MAP3K3Q997592, 3MINT-48453 I2D: score=2 
    HSP90AA1P079002, 3, ENSP000003351534MINT-7945693 MINT-7947479 I2D: score=1 STRING: ENSP00000335153
    ENSG00000206435P305043I2D: score=1 
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000087M phase of mitotic cell cycle TAS--
    GO:0000236mitotic prometaphase TAS--
    GO:0000278mitotic cell cycle TAS--
    GO:0000910cytokinesis TAS--
    GO:0007097nuclear migration ----


    NUDC for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Search CenterWatch for drugs/clinical trials and news about NUDC 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NUDC gene: 
    NM_006600.3  

    Unigene Cluster for NUDC:

    Nuclear distribution C homolog (A. nidulans)
    Hs.263812  [show with all ESTs]
    Unigene Representative Sequence: BG121847
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000435827 ENST00000321265(uc001bng.1) ENST00000452707 ENST00000484772


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    Additional cDNA sequence: 

    AB019408.1 AF086922.1 AF100760.1 AF125465.1 AF130736.1 AF241788.1 AL136725.1 BC002399.2 
    BC003132.1 BC006147.1 BC007280.1 BC015153.1 BC021139.1 

    24/28 DOTS entries (see all 28):

    DT.99962005  DT.99939309  DT.451875  DT.95173020  DT.100822554  DT.40315649  DT.92455003  DT.120988715 
    DT.95173038  DT.100822557  DT.86856462  DT.100822560  DT.121392790  DT.95173036  DT.100031365  DT.100822547 
    DT.100822556  DT.100822561  DT.121392759  DT.121392776  DT.121392778  DT.121392795  DT.92455012  DT.95173023 

    24/685 AceView cDNA sequences (see all 685):

    BM910560 BQ233650 BI833166 BE894965 AA456185 CR590748 BM542213 BQ653730 
    CD370203 R89449 AA443120 AW276284 BQ644056 BM561878 BM673180 F22224 
    BQ883044 BQ892863 CD515367 BF220100 BQ925555 BM475079 BU191558 AI110826 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for NUDC (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b
    SP1:                          -           -     -                 -                       -                           
    SP2:                          -           -                       -                                                   
    SP3:                                      -     -                                                                     
    SP4:                          -     -     -     -                                                                     
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for NUDC

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NUDC expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGACTGGCCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See NUDC Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NUDC

    SOURCE GeneReport for Unigene cluster: Hs.263812

    UniProtKB/Swiss-Prot: NUDC_HUMAN, Q9Y266
    Tissue specificity: Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult
    pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NUDC gene from 9/34 species (see all 34)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nudc1 , 5 nuclear distribution gene C homolog (Aspergillus)1, 5 89.63(n)1
    94.26(a)1
      4 (66.25 cM)5
    182211  NM_010948.31  NP_035078.11 
     1335325425 
    chicken
    (Gallus gallus)
    Aves NUDC1 nuclear distribution gene C homolog (A. nidulans) 75.77(n)
    82.21(a)
      419578  NM_001006311.1  NP_001006311.1 
    lizard
    (Anolis carolinensis)
    Reptilia NUDC6
    --
    79(a)
    1 ↔ 1
    GL343488.1(190863-200680)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.41832 Xenopus laevis transcribed sequence with weak similarity more 75.7(n)    CF549165.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc560992 similar to nuclear distribution gene C homolog (Aspergillus) 76.25(n)   393893  BC045909.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG97103
    nudC1
    CG9710-PA1 48(a)3
    58.74(n)1
    54.01(a)1
      73D13
    398791  NM_140666.31  NP_648923.11 
    worm
    (Caenorhabditis elegans)
    Secernentea nud-11 , 3 Protein NUD-11 49(a)3
    54.99(n)1
    50.96(a)1
      III(13412514-13413669)3
    1767541  NM_067348.51  NP_499749.11 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G278901 HSP20-like chaperone 55.1(n)
    47.95(a)
      828902  NM_118927.4  NP_194518.1 
    rice
    (Oryza sativa)
    Liliopsida Os.140072 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 73(n)    AK073934.1 


    ENSEMBL Gene Tree for NUDC (if available)
    TreeFam Gene Tree for NUDC (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NUDC gene
    NUDCD32  
    1 SIMAP similar gene for NUDC using alignment to 2 protein entries:     NUDC_HUMAN (see all proteins):
    NUDCD3

    NUDC for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for NUDC
    PGOHUM00000258148 PGOHUM00000241033


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/459 NCBI SNPs in NUDC are shown (see all 459    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs120881511,2
    C--27246459(+) TCAGTC/TTGAGG 1 -- us2k12Minor allele frequency- T:0.00NA 4
    rs1863565071,2
    --27246694(+) GACTAC/GAACAG 1 -- us2k10--------
    rs1385215331,2
    --27246706(+) CCGGGC/TGCAGT 1 -- us2k10--------
    rs1913179801,2
    --27246711(+) CGCAGC/TGGCTC 1 -- us2k10--------
    rs1427049291,2
    --27246736(+) AGCGCA/GTTGCG 1 -- us2k10--------
    rs1473613111,2
    --27246844(+) TAGGCA/GTAGTG 1 -- us2k10--------
    rs115841591,2
    H--27246898(+) acctgA/Ggaggc 1 -- us2k10--------
    rs1416640891,2
    C,--27246954(+) GCAAC-/AGAGTGA 1 -- us2k10--------
    rs2008294521,2
    --27247101(+) GAAAG-/TGGGGC 1 -- us2k10--------
    rs1817886401,2
    --27247153(+) CACACC/TTGTAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for NUDC (27226729 - 27273353 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for NUDC
         1 CNV: 4218
    Human Gene Mutation Database (HGMD): NUDC

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NUDC for disorders           About GeneDecksing

    OMIM gene information: 610325    OMIM disorders: --

    9 diseases for NUDC:    About MalaCards
    lymphoblastic leukemia    lissencephaly    hematopoiesis    nasopharyngitis
    leukemia    malaria    prostatitis    neuronitis
    carcinoma

    1 disease from the University of Copenhagen DISEASES database for NUDC:
    Lissencephaly

    1 Novoseek disease relationship for NUDC gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    lymphoblastic leukemia acute 29.5 2 10210332 (1)


    Export disorders for NUDC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NUDC gene, integrated from 9 sources (see all 63):
    (articles sorted by number of sources associating them with NUDC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis. (PubMed id 10210332)1, 2, 9 Miller B.A.... Osmani S.A. (1999)
    2. A role for Plk1 phosphorylation of NudC in cytokinesis. (PubMed id 12852857)1, 2, 9 Zhou T.... Erikson R.L. (2003)
    3. Molecular cloning and characterization of the human NUDC gene. (PubMed id 10453739)1, 2, 9 Matsumoto N. and Ledbetter D.H. (1999)
    4. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis. (PubMed id 12679384)1, 2 Aumais J.P.... Yu-Lee L.-Y. (2003)
    8. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    9. A microtubule associated protein (hNUDC) binds to the extracellular domain of thrombopoietin receptor (Mpl). (PubMed id 16088917)1, 9 Pan R.M....Xu P. (2005)
    10. NudC is required for Plk1 targeting to the kinetochore and chromosome congression. (PubMed id 16860740)1, 9 Nishino M....Yu-Lee L.Y. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10726 HGNC: 8045 AceView: NUDC Ensembl:ENSG00000090273 euGenes: HUgn10726
    ECgene: NUDC H-InvDB: NUDC

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NUDC Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NUDC gene:
    Search GeneIP for patents involving NUDC

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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