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NUCKS1 Gene

protein-coding   GIFtS: 53
GCID: GC01M205681

Nuclear Casein Kinase And Cyclin-Dependent Kinase Substrate...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nuclear Casein Kinase And Cyclin-Dependent Kinase Substrate 11 2
NUCKS2 3 5
P12 3
Nuclear Ubiquitous Casein And Cyclin-Dependent Kinase Substrate 12
Nuclear Ubiquitous Casein Kinase And Cyclin-Dependent Kinase Substrate2
Potential LAG1 Interactor2

External Ids:    HGNC: 299231   Entrez Gene: 647102   Ensembl: ENSG000000692757   OMIM: 6119125   UniProtKB: Q9H1E33   

Export aliases for NUCKS1 gene to outside databases

Previous GC identifers: GC01M202419 GC01M203948 GC01M176846


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NUCKS1 Gene:
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein
contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative
nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis
of the cell cycle. (provided by RefSeq, Aug 2010)

GeneCards Summary for NUCKS1 Gene:
NUCKS1 (nuclear casein kinase and cyclin-dependent kinase substrate 1) is a protein-coding gene. Diseases associated with NUCKS1 include breast fibroadenoma, and breast adenocarcinoma.

Gene Wiki entry for NUCKS1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NUCKS1 gene promoter:
         Spz1   p53   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUCKS1 promoter sequence
   Search Chromatin IP Primers for NUCKS1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NUCKS1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.1   Ensembl cytogenetic band:  1q32.1   HGNC cytogenetic band: 1q32.1

NUCKS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUCKS1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M205681:  view genomic region     (about GC identifiers)

Start:
205,681,947 bp from pter      End:
205,719,404 bp from pter
Size:
37,458 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NUCKS_HUMAN, Q9H1E3 (See protein sequence)
Recommended Name: Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1  
Size: 243 amino acids; 27296 Da
Sequence caution: Sequence=BAB15076.1; Type=Erroneous termination; Positions=164; Note=Translated as Arg;
Sequence=CAC20412.1; Type=Erroneous gene model prediction;
Secondary accessions: Q54AC0 Q5PXE7 Q9H1D6 Q9H723
Alternative splicing: 2 isoforms:  Q9H1E3-1   Q9H1E3-2   

Explore the universe of human proteins at neXtProt for NUCKS1: NX_Q9H1E3

Explore proteomics data for NUCKS1 at MOPED

Post-translational modifications: 

  • Phosphorylated by CDK1 and casein kinase1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NUCKS1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_073568.2  
    ENSEMBL proteins: 
     ENSP00000356110  

    NUCKS1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for NUCKS1

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    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    LSBio Antibodies in human, mouse, rat for NUCKS1

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    Cloud-Clone Corp. ELISAs for NUCKS1
    Cloud-Clone Corp. CLIAs for NUCKS1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026633 NUCKS1

    Graphical View of Domain Structure for InterPro Entry Q9H1E3

    ProtoNet protein and cluster: Q9H1E3


    NUCKS1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0044822poly(A) RNA binding IDA--
         
    NUCKS1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NUCKS1:
     Increased Salmonella enterica  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NUCKS1
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NUCKS1

    miRNA
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    miRTarBase miRNAs that target NUCKS1:
    hsa-mir-484 (MIRT042079), hsa-mir-155-5p (MIRT021020), hsa-mir-505-5p (MIRT037956), hsa-mir-503-5p (MIRT041110), hsa-mir-301a-3p (MIRT044229), hsa-mir-34a-5p (MIRT025293), hsa-mir-149-5p (MIRT045409), hsa-mir-93-3p (MIRT038841), hsa-mir-877-3p (MIRT037093), hsa-let-7b-5p (MIRT052210), hsa-mir-877-5p (MIRT037345), hsa-mir-17-5p (MIRT050890), hsa-mir-16-2-3p (MIRT038707), hsa-mir-192-5p (MIRT026814), hsa-mir-193b-3p (MIRT041206), hsa-mir-505-3p (MIRT041030), hsa-mir-215-5p (MIRT024393)

    Block miRNA regulation of human, mouse, rat NUCKS1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NUCKS1 (see all 96):
    hsa-miR-411* hsa-miR-140-5p hsa-miR-4254 hsa-miR-300 hsa-miR-146a hsa-miR-200a hsa-miR-30d hsa-miR-502-3p
    SwitchGear 3'UTR luciferase reporter plasmidNUCKS1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat NUCKS1

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    GenScript: all cDNA clones in your preferred vector: NUCKS1 (NM_022731)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NUCKS1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUCKS1

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUCKS1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NUCKS_HUMAN, Q9H1E3: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    NUCKS1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NUCKS1
    Interactions:

        Search GeneGlobe Interaction Network for NUCKS1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    Selected Interacting proteins for NUCKS1 (Q9H1E32, 3 ENSP000003561104) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AK5Q9Y6K83I2D: score=4 
    MMEP084733I2D: score=2 
    MDM2Q009873I2D: score=1 
    WNK1Q9H4A33I2D: score=1 
    YWHAZP631043I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NUCKS1 (NUCKS)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NUCKS1 gene: 
    NM_022731.4  

    Unigene Cluster for NUCKS1:

    Nuclear casein kinase and cyclin-dependent kinase substrate 1
    Hs.213061  [show with all ESTs]
    Unigene Representative Sequence: EU137727
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367142(uc001hdb.3) ENST00000464938
    miRNA
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    Block miRNA regulation of human, mouse, rat NUCKS1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NUCKS1 (see all 96):
    hsa-miR-411* hsa-miR-140-5p hsa-miR-4254 hsa-miR-300 hsa-miR-146a hsa-miR-200a hsa-miR-30d hsa-miR-502-3p
    SwitchGear 3'UTR luciferase reporter plasmidNUCKS1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NUCKS1
    Predesigned siRNA for gene silencing in human, mouse, rat NUCKS1
    Clone
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    OriGene ORF clones in mouse, rat for NUCKS1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NUCKS1 (NM_022731)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NUCKS1
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for NUCKS1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NUCKS1
      QuantiTect SYBR Green Assays in human, mouse, rat NUCKS1
      QuantiFast Probe-based Assays in human, mouse, rat NUCKS1

    Additional mRNA sequence: 

    AF130080.2 AK056578.1 AK095855.1 AK311186.1 AL831976.1 BC025313.1 EU137727.1 

    Selected DOTS entries (see all 39):

    DT.100045200  DT.91782357  DT.95216577  DT.95328755  DT.121456164  DT.95216514  DT.100646744  DT.121456338 
    DT.91782327  DT.101969329  DT.121456251  DT.100677827  DT.121456183  DT.95133072  DT.121456206  DT.121456232 
    DT.100850587  DT.121456165  DT.91782343  DT.121456168  DT.455711  DT.121456195  DT.95216597  DT.95216598 

    Selected AceView cDNA sequences (see all 1194):

    AA603745 BQ222104 AA557372 BU902721 AA205151 BI062466 BU507038 BM834485 
    AI559138 AI741416 AW731725 BI062159 AA199728 Z44407 AA442807 CB152932 
    BU783080 AI799912 CA395178 BM697471 AI631333 BC039469 BF718293 AL599451 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for NUCKS1    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6
    SP1:                                          
    SP2:                                          


    ECgene alternative splicing isoforms for NUCKS1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NUCKS1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAGATGTGG
    NUCKS1 Expression
    About this image

    NUCKS1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NUCKS1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.213061

    UniProtKB/Swiss-Prot: NUCKS_HUMAN, Q9H1E3
    Tissue specificity: Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal
    liver, thymus and lung

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for NUCKS1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nucks11 , 5 nuclear casein kinase and cyclin-dependent kinase substrate more1, 5 90.6(n)1
    94.44(a)1
      1 (57.22 cM)5
    984151  NM_175294.31  NP_780503.21 
     1319104585 
    chicken
    (Gallus gallus)
    Aves NUCKS11 nuclear casein kinase and cyclin-dependent kinase substrate more 84.57(n)
    93.39(a)
      404775  NM_213581.1  NP_998746.1 
    lizard
    (Anolis carolinensis)
    Reptilia NUCKS16
    nuclear casein kinase and cyclin-dependent kinase ...
    74(a)
    1 ↔ 1
    GL343228.1(600003-632085)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia MGC757382 hypothetical protein MGC75738 76.75(n)    BC063335.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nucks1a1 nuclear casein kinase and cyclin-dependent kinase substrate more 59.78(n)
    57.85(a)
      447862  NM_001004601.2  NP_001004601.1 


    ENSEMBL Gene Tree for NUCKS1 (if available)
    TreeFam Gene Tree for NUCKS1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NUCKS1 gene
    1 SIMAP similar gene for NUCKS1 using alignment to 1 protein entry:     NUCKS_HUMAN:
    NUCKS

    NUCKS1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NUCKS1
    PGOHUM00000261298


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NUCKS1 (see all 733)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs722546471,2
    C--205709125(+) TTTTT-/TT/TTT
            
    TTTTT
    2 -- int1 cds10--------
    rs608663781,2
    C--205709146(+) TTTTT-/TTT   
       
    /TTTT
    GAGAG
    2 -- int1 cds11NA 2
    rs569799231,2
    C--205710426(+) AAAAAAA/-GAAAA 1 -- int11Minor allele frequency- -:0.50NA 2
    rs719705051,2
    C--205712197(+) TGGCC-/ATGC  
     AGACTGT
    AAGTC
    1 -- int10--------
    rs711524491,2
    C--205712198(-) TGACT-/TACA  
     GTCTGCA
    TGGCC
    1 -- int11Minor allele frequency- TACAGTCTGCA:0.00NA 2
    rs557379371,2
    C--205714617(+) TCTCC-/AAAAAA 1 -- int10--------
    rs105390471,2
    C--205715565(+) TCACT-/TCTC  
      TCTCTC
    TCTCT
    1 -- int1 trp30--------
    rs610111581,2
    C--205715565(+) TCACT-/TCT   
       CTCTC
    TCTCT
    1 -- int10--------
    rs1112659461,2
    C--205719191(+) AACTTA/C/GAGCCG 2 -- ut512CSA NA 121
    rs112405551,2
    F--212219772(+) ggtggC/Tgtatg 1 -- ds50011Minor allele frequency- T:0.50CSA 2

    HapMap Linkage Disequilibrium report for NUCKS1 (205681947 - 205719404 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NUCKS1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NUCKS1
    DNA2.0 Custom Variant and Variant Library Synthesis for NUCKS1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611912    OMIM disorders: --

    14 diseases for NUCKS1:    
    About MalaCards
    breast fibroadenoma    breast adenocarcinoma    lung adenocarcinoma    adenocarcinoma
    parkinson's disease    systemic lupus erythematosus    lupus erythematosus    schizophrenia
    retinitis    thyroiditis    prostatitis    prostate cancer
    colorectal cancer    breast cancer


    NUCKS1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NUCKS1
    Human Genome Epidemiology (HuGE) Navigator: NUCKS1 (4 documents)

    Export disorders for NUCKS1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NUCKS1 gene, integrated from 10 sources (see all 58):
    (articles sorted by number of sources associating them with NUCKS1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo. (PubMed id 11298763)1, 2, 3 Oestvold A.C....Grundt K. (Eur. J. Biochem. 2001)
    2. Characterisation of the NUCKS gene on human chromosome 1q32.1 and the presence of a homologous gene in different species. (PubMed id 15381070)1, 2, 9 Grundt K....Ostvold A.C. (Biochem. Biophys. Res. Commun. 2004)
    3. Genetic variability at the PARK16 locus. (PubMed id 20683486)1, 4 Tucci A....PaisA!n-Ruiz C. (Eur. J. Hum. Genet. 2010)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Genome-wide association study reveals genetic risk underlying Parkinson's disease. (PubMed id 19915575)1, 4 SimA^n-SA!nchez J....Gasser T. (Nat. Genet. 2009)
    6. Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. (PubMed id 19915576)1, 4 Satake W....Toda T. (Nat. Genet. 2009)
    7. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    8. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64710 HGNC: 29923 AceView: NUCKS Ensembl:ENSG00000069275 euGenes: HUgn64710
    ECgene: NUCKS1 H-InvDB: NUCKS1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NUCKS1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NUCKS1 gene:
    Search GeneIP for patents involving NUCKS1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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