NUBPL Gene
protein-coding GIFtS: 47
GCID: GC14P031959
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|
nucleotide binding protein-like(Previous name: chromosome 14 open reading frame 127 ) (Previous symbol: C14orf127)
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Aliases for NUBPL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Nucleotide Binding Protein-Like1 2 | | FLJ126601 | | C14orf1271 2 3 | | Chromosome 14 Open Reading Frame 1271 | | HuInd11 | | Iron-Sulfur Protein NUBPL2 | | IND11 2 5 | | Iron-Sulfur Protein Required For NADH Dehydrogenase2 | | IND1 Homolog2 3 | | Nucleotide-Binding Protein-Like3 |
Export aliases for NUBPL gene to outside databasesPrevious GC identifers: GC14P031101 GC14P032032 GC14P012147 |
Summaries for NUBPL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for NUBPL: This gene encodes a member of the Mrp/NBP35 ATP-binding proteins family. The encoded protein is required for theassembly of the respiratory chain NADH dehydrogenase (complex I), an oligomeric enzymatic complex located in the innermitochondrial membrane. The respiratory complex I consists of 45 subunits and 8 iron-sulfur (Fe/S) clusters. Thisprotein is an Fe/S protein that plays a critical role in the assembly of respiratory complex I, likely by transferringFe/S into the Fe/S-containing complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency.Alternatively spliced transcript variants encoding distinct isoforms have been identified.(provided by RefSeq, Jan2011) UniProtKB/Swiss-Prot: NUBPL_HUMAN, Q8TB37Function: Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Maydeliver of one or more Fe-S clusters to complex I subunits
|
Genomic Views for NUBPL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the NUBPL gene promoter: SRF MEF-2 SRF (504 AA) HNF-3beta MEF-2A E2F E2F-1 COMP1 Sox9 Other transcription factors
Search SABiosciences Chromatin IP Primers for NUBPL
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUBPL |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q12 Ensembl cytogenetic band: 14q12 HGNC cytogenetic band: 14q12NUBPL Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P031959: view genomic region
(about GC identifiers)
Start:
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31,959,162 bp from pter |
End:
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32,330,430 bp from pter |
Size:
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371,269 bases |
Orientation:
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plus strand |
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Proteins for NUBPL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: NUBPL_HUMAN, Q8TB37 (See
protein sequence)Recommended Name: Iron-sulfur protein NUBPL precursor Size: 319 amino acids; 34083 Da
Cofactor: Binds 1 4Fe-4S cluster
Subcellular location: Mitochondrion
Sequence caution: Sequence=AAH24919.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAB14203.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAD62349.1;Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B4DHZ1 Q86TZ4 Q9H9M2Alternative splicing: 2 isoforms: Q8TB37-1 Q8TB37-2 (May be due to exon skipping)Explore the universe of human proteins at neXtProt for NUBPL: NX_Q8TB37
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TB37 NUBPL Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (3 alternative transcripts):
NP_001188502.1 NP_001188503.1 NP_079428.2 ENSEMBL proteins: ENSP00000446511 ENSP00000447618 ENSP00000281081 ENSP00000449918 ENSP00000447316 ENSP00000447658 ENSP00000447234 ENSP00000439286 Human Recombinant Protein Products for NUBPL:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table
NUBPL for ontologies About GeneDecksing
NUBPL Antibody Products: Assay Products for NUBPL: |
Protein
Domains / Families for NUBPL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NUBPL for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8TB37ProtoNet protein and cluster: Q8TB37 1 Blocks protein family: IPB000808 Mrp family
UniProtKB/Swiss-Prot: NUBPL_HUMAN, Q8TB37Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family |
Function for NUBPL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: NUBPL_HUMAN, Q8TB37Function: Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Maydeliver of one or more Fe-S clusters to complex I subunits Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
NUBPL for ontologies About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUBPL (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUBPL (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUBPL |
|
Pathways & Interactions for NUBPL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUBPL
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
 4 Interacting proteins for NUBPL (Q8TB373 ENSP000002810814) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
NUBPL for ontologies About GeneDecksing
|
Drugs & Compounds for NUBPL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
NUBPL for compounds About GeneDecksing
Browse Tocris compounds for NUBPL 1 PharmGKB related drug/compound annotation for NUBPL gene About this tableSearch CenterWatch for drugs/clinical trials and news about NUBPL 
|
Transcripts for NUBPL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for NUBPL gene (3 alternative transcripts): NM_001201573.1 NM_001201574.1 NM_025152.2 Unigene Cluster for NUBPL: Nucleotide binding protein-like Hs.288981 [show with all ESTs]Unigene Representative Sequence: NM_02515214 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000550005 ENST00000552814 ENST00000550649 ENST00000281081(uc001wrk.4 uc010amj.3 uc010tpl.2 uc021rsb.1) ENST00000547839 ENST00000548937 ENST00000552489 ENST00000549838 ENST00000550355 ENST00000551314 ENST00000418681 ENST00000551015 ENST00000552888 ENST00000536705
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUBPL (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUBPL (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): NUBPL (NM_001201573) | |  | DNA2.0 Custom Codon Optimized Gene
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Additional cDNA sequence: AK022722.1 AK093789.1 AK295326.1 AK301447.1 AK316445.1 BC024919.1 11 DOTS entries: DT.86849801 DT.91707885 DT.100778130 DT.120791565 DT.100020105 DT.100778129 DT.95210295 DT.120791560 DT.91850890 DT.97839304 DT.99941749 24/75 AceView cDNA sequences (see all 75): BX248028 AI278310 BM978769 CB157739 BM828160 AW271814 AI310371 AA830432 AA232131 AA909668 BP378262 AA252906 CA867100 AA253312 AI318390 AW105206 AA232618 AI521965 CA422829 BI764999 BV203222 AA598545 AA884084 AI829643 GeneLoc Exon Structure
|
Expression for NUBPL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NUBPL expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TAAATCTACA
 About this image See NUBPL Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for NUBPL
SOURCE GeneReport for Unigene cluster: Hs.288981
UniProtKB/Swiss-Prot: NUBPL_HUMAN, Q8TB37Tissue specificity: Highest expression in liver and kidney. expressed at significant levels in small intestine andbrain (at protein level) SABiosciences Custom PCR Arrays for NUBPL
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUBPL Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NUBPL | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUBPL | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUBPL | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUBPL |
Orthologs for NUBPL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for NUBPL gene from 10/38 species (see all 38) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Nubpl1 , 5 |
nucleotide binding protein-like1, 5 |
86.73(n)1 88.09(a)1 |
  |
12 (22.11 cM)5 768261 NM_029760.21 NP_084036.21 520977375 |
chicken (Gallus gallus) |
Aves |
NUBPL1 |
nucleotide binding protein-like |
73.78(n) 78.67(a) |
  |
423312 XM_421229.1 XP_421229.1 |
lizard (Anolis carolinensis) |
Reptilia |
NUBPL6NUBP16 |
-- |
75(a)33(a) |
1 ↔ 1possible ortholog |
2(56658981-56682948) GL343592.1(311059-319286) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.142742 |
Xenopus laevis transcribed sequence with moderate similarity more |
73.08(n) |
  |
CA972549.1 |
zebrafish (Danio rerio) |
Actinopterygii |
nubpl1 |
nucleotide binding protein-like |
70.16(n) 78.7(a) |
  |
436715 NM_001002442.1 NP_001002442.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG32621 |
CG3262 |
53.02(n) 45.56(a) |
  |
35452 NM_136299.4 NP_610143.3 |
worm (Caenorhabditis elegans) |
Secernentea |
F10G8.66 |
Cytosolic Fe-S cluster assembly factor NUBP1 homol... |
32(a) |
possible ortholog |
I(10046429-10048017) |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
INDL1 |
ATP-binding protein involved in chromosome partitioning |
59.1(n) 60.16(a) |
  |
827696 NM_118074.1 NP_193689.1 |
rice (Oryza sativa) |
Liliopsida |
Os.273412 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
70.87(n) |
  |
AK106686.1 |
E. coli (Escherichia coli) |
Gamma proteobacteria |
mrp6 |
antiporter inner membrane protein |
36(a) |
1 ↔ 1 |
Chromosome(2191081-2192190) |
ENSEMBL Gene Tree for NUBPL (if available) TreeFam Gene Tree for NUBPL (if available)  |
Paralogs for NUBPL gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for NUBPL gene
- NUBP12
2 SIMAP similar genes for NUBPL using alignment to 7 protein entries: NUBPL_HUMAN (see all proteins):NUBP2 NUBP1
NUBPL for paralogs About GeneDecksing
|
Genomic Variants for NUBPL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 14 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for NUBPL (31959162 - 32209162 bp, first 250kb of NUBPL)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 3 variations for NUBPL 1 CNV: 5735 2 Indels: 49338 60143 Human Gene Mutation Database (HGMD): NUBPL
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUBPL |
|
Disorders
/ Diseases for NUBPL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NUBPL for disorders About GeneDecksing
OMIM gene information: 613621 OMIM disorders: 252010 UniProtKB/Swiss-Prot: NUBPL_HUMAN, Q8TB37
Defects in NUBPL are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of themitochondrial respiratory chain that causes a wide range of clinical manifestations from lethal neonatal disease toadult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specificencephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and someforms of Parkinson disease 14 diseases for NUBPL: About MalaCardsmitochondrial complex i deficiency leber hereditary optic neuropathy leukodystrophy multiple sclerosis stomatitis acute t cell leukemia neuropathy parkinson's disease t-cell leukemia schizophrenia tuberculosis malaria leukemia mycobacterium tuberculosis Human Genome Epidemiology (HuGE) Navigator: NUBPL (2 documents) Export disorders for NUBPL gene to outside databases
|
Publications for NUBPL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NUBPL gene, integrated from 9 sources (see all 15): (articles sorted by number of sources associating them with NUBPL) | |  | Utopia: connect your pdf to the dynamic world of online information |
- High-throughput, pooled sequencing identifies mutatio ns in NUBPL and FOXRED1 in human complex I deficiency. (PubMed id 20818383)1, 2 Calvo S.E....Mootha V.K. (2010)
- Human ind1, an iron-sulfur cluster assembly factor fo r respiratory complex I. (PubMed id 19752196)1, 2 Sheftel A.D....Lill R. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Next generation sequencing in molecular diagnosis: NUBPL mutations highlight the challenges of variant detection and interpretation. (PubMed id 22072591)2 Tucker E.J....Thorburn D.R. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Genome-wide association study of antipsychotic-induce d QTc interval prolongation. (PubMed id 20921969)1 Aberg K....van den Oord E.J. (2010)
- Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
- Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PubMed id 19010793)1 Baranzini S.E....Oksenberg J.R. (2008)
- Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia. (PubMed id 18521091)1 Volpi S....Lavedan C. (2008)
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External Searches for NUBPL gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing NUBPL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NUBPL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NUBPL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for NUBPL | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NUBPL gene: Search GeneIP for patents involving NUBPL
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for NUBPL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for NUBPL | | OriGene shRNA RFP for NUBPL | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NUBPL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NUBPL | | OriGene Protein Over-expression Lysate for NUBPL | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for NUBPL | | OriGene 3'-UTR Clone for NUBPL | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NUBPL | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NUBPL | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for NUBPL | | OriGene Custom Protein Services for NUBPL | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NUBPL | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NUBPL | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUBPL | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NUBPL | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUBPL | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NUBPL |
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| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NUBPL |
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