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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NUBPL Gene

protein-coding   GIFtS: 50
GCID: GC14P031959

Nucleotide Binding Protein-Like

(Previous name: chromosome 14 open reading frame 127)
(Previous symbol: C14orf127)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Nucleotide Binding Protein-Like1 2     IND12 5
C14orf1271 2 3     Chromosome 14 Open Reading Frame 1271
Iron-Sulfur Protein Required For NADH Dehydrogenase1 2     Iron-Sulfur Protein NUBPL2
huInd12 3     Nucleotide-Binding Protein-Like3
IND1 Homolog2 3     

External Ids:    HGNC: 202781   Entrez Gene: 802242   Ensembl: ENSG000001514137   OMIM: 6136215   UniProtKB: Q8TB373   

Export aliases for NUBPL gene to outside databases

Previous GC identifers: GC14P031101 GC14P032032 GC14P012147


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NUBPL Gene:
This gene encodes a member of the Mrp/NBP35 ATP-binding proteins family. The encoded protein is required for the
assembly of the respiratory chain NADH dehydrogenase (complex I), an oligomeric enzymatic complex located in the
inner mitochondrial membrane. The respiratory complex I consists of 45 subunits and 8 iron-sulfur (Fe/S)
clusters. This protein is an Fe/S protein that plays a critical role in the assembly of respiratory complex I,
likely by transferring Fe/S into the Fe/S-containing complex I subunits. Mutations in this gene cause
mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding distinct isoforms have
been identified.(provided by RefSeq, Jan 2011)

GeneCards Summary for NUBPL Gene: 
NUBPL (nucleotide binding protein-like) is a protein-coding gene. Diseases associated with NUBPL include acute t cell leukemia, and mitochondrial complex i deficiency. GO annotations related to this gene include 4 iron, 4 sulfur cluster binding and metal ion binding. An important paralog of this gene is NUBP1.

UniProtKB/Swiss-Prot: NUBPL_HUMAN, Q8TB37
Function: Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex
I). May deliver of one or more Fe-S clusters to complex I subunits




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  NC_018925.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NUBPL gene promoter:
         SRF   MEF-2   SRF (504 AA)   HNF-3beta   MEF-2A   E2F   E2F-1   COMP1   Sox9   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNUBPL promoter sequence
   Search SABiosciences Chromatin IP Primers for NUBPL

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NUBPL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q12   Ensembl cytogenetic band:  14q12   HGNC cytogenetic band: 14q12

NUBPL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NUBPL gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P031959:  view genomic region     (about GC identifiers)

Start:
31,959,162 bp from pter      End:
32,330,430 bp from pter
Size:
371,269 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NUBPL_HUMAN, Q8TB37 (See protein sequence)
Recommended Name: Iron-sulfur protein NUBPL precursor  
Size: 319 amino acids; 34083 Da
Cofactor: Binds 1 4Fe-4S cluster
Subcellular location: Mitochondrion
Sequence caution: Sequence=AAH24919.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB14203.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAD62349.1;
Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B4DHZ1 Q86TZ4 Q9H9M2
Alternative splicing: 2 isoforms:  Q8TB37-1   Q8TB37-2   (May be due to exon skipping)

Explore the universe of human proteins at neXtProt for NUBPL: NX_Q8TB37

Explore proteomics data for NUBPL at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TB37

  • NUBPL Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NUBPL Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001188502.1  NP_001188503.1  NP_079428.2  

    ENSEMBL proteins: 
     ENSP00000446511   ENSP00000447618   ENSP00000281081   ENSP00000449918   ENSP00000447316  
     ENSP00000447658   ENSP00000447234   ENSP00000439286  

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    Cloud-Clone Corp. Proteins for NUBPL 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA19752196

    NUBPL for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    MITOAF: Mitochondrial respiratory chain complex assembly factors

    4 InterPro protein domains:
     IPR019591 ATPase-like_ParA/MinD
     IPR000808 Mrp_CS
     IPR027417 P-loop_NTPase
     IPR025669 AAA_dom

    Graphical View of Domain Structure for InterPro Entry Q8TB37

    ProtoNet protein and cluster: Q8TB37

    1 Blocks protein domain: IPB000808 Mrp family

    UniProtKB/Swiss-Prot: NUBPL_HUMAN, Q8TB37
    Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family


    NUBPL for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NUBPL_HUMAN, Q8TB37
    Function: Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex
    I). May deliver of one or more Fe-S clusters to complex I subunits

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005524ATP binding IEA--
    GO:0046872metal ion binding IEA--
    GO:00515394 iron, 4 sulfur cluster binding IDA19752196
         
    NUBPL for ontologies           About GeneDecksing


    Animal Models:
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    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidNUBPL 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NUBPL

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for NUBPL (Q8TB373 ENSP000002810814) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATG10Q9H0Y03I2D: score=1 
    C10orf2ENSP000003095954STRING: ENSP00000309595
    NARFLENSP000002515884STRING: ENSP00000251588
    --ENSP000002622664STRING: ENSP00000262266
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032981mitochondrial respiratory chain complex I assembly IMP19752196
    GO:0070584mitochondrion morphogenesis IMP19752196

    NUBPL for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    NUBPL for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NUBPL

    1 PharmGKB related drug/compound annotation for NUBPL gene    About this table
    Drug/compound PharmGKB Annotation
    iloperidoneCA  

    Search CenterWatch for drugs/clinical trials and news about NUBPL

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NUBPL gene (3 alternative transcripts): 
    NM_001201573.1  NM_001201574.1  NM_025152.2  

    Unigene Cluster for NUBPL:

    Nucleotide binding protein-like
    Hs.288981  [show with all ESTs]
    Unigene Representative Sequence: NM_025152
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000550005 ENST00000552814 ENST00000550649 ENST00000281081(uc001wrk.4 uc010amj.3 uc010tpl.2 uc021rsb.1)
    ENST00000547839 ENST00000548937 ENST00000552489 ENST00000549838 ENST00000550355
    ENST00000551314 ENST00000418681 ENST00000551015 ENST00000552888 ENST00000536705


    miRNA
    Products:
         
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    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate NUBPL (see all 22):
    hsa-miR-136 hsa-miR-361-5p hsa-miR-4307 hsa-miR-607 hsa-miR-137 hsa-miR-2110 hsa-miR-374a* hsa-miR-3658
    SwitchGear 3'UTR luciferase reporter plasmidNUBPL 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NUBPL

    Additional mRNA sequence: 

    AK022722.1 AK093789.1 AK295326.1 AK301447.1 AK316445.1 BC024919.1 

    11 DOTS entries:

    DT.86849801  DT.91707885  DT.100778130  DT.120791565  DT.100020105  DT.100778129  DT.95210295  DT.120791560 
    DT.91850890  DT.97839304  DT.99941749 

    24/75 AceView cDNA sequences (see all 75):

    AA232131 BM828160 AA232618 BX248028 AA830432 AW105206 BM978769 BP378262 
    CA867100 AI278310 AI521965 AA252906 AW271814 AI310371 AA253312 CB157739 
    AI318390 AA909668 AI401690 AI829643 BX451349 AW292775 AA761798 AA598545 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NUBPL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAATCTACA
    NUBPL Expression
    About this image


    See NUBPL Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NUBPL

    SOURCE GeneReport for Unigene cluster: Hs.288981

    UniProtKB/Swiss-Prot: NUBPL_HUMAN, Q8TB37
    Tissue specificity: Highest expression in liver and kidney. expressed at significant levels in small intestine and
    brain (at protein level)

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NUBPL gene from 9/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nubpl1 , 5 nucleotide binding protein-like1, 5 86.73(n)1
    88.09(a)1
      12 (22.11 cM)5
    768261  NM_029760.21  NP_084036.21 
     520977375 
    chicken
    (Gallus gallus)
    Aves NUBPL1 nucleotide binding protein-like 73.78(n)
    78.67(a)
      423312  XM_421229.1  XP_421229.1 
    lizard
    (Anolis carolinensis)
    Reptilia NUBPL6
    Uncharacterized protein
    75(a)
    1 ↔ 1
    2(56658656-56682948)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.142742 Xenopus laevis transcribed sequence with moderate similarity more 73.08(n)    CA972549.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nubpl1 nucleotide binding protein-like 70.16(n)
    78.7(a)
      436715  NM_001002442.1  NP_001002442.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG32621 CG3262 53.02(n)
    45.56(a)
      35452  NM_136299.4  NP_610143.3 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NBP356
    Essential iron-sulfur cluster binding protein loca...
    29(a)
    1 → many
    VII(342056-343042)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons INDL1 ATP-binding protein involved in chromosome partitioning 59.1(n)
    60.16(a)
      827696  NM_118074.1  NP_193689.1 
    rice
    (Oryza sativa)
    Liliopsida Os.273412 Oryza sativa (japonica cultivar-group) cDNA clone0 more 70.87(n)    AK106686.1 


    ENSEMBL Gene Tree for NUBPL (if available)
    TreeFam Gene Tree for NUBPL (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NUBPL gene
    NUBP12  
    2 SIMAP similar genes for NUBPL using alignment to 7 protein entries:     NUBPL_HUMAN (see all proteins):
    NUBP2    NUBP1

    NUBPL for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6835 SNPs in NUBPL are shown (see all 6835)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0278954
    ----see VAR_0278952 N T mis40--------
    VAR_0645704
    ----see VAR_0645702 G R mis40--------
    rs672597551,2
    C--12149115(+) TTTTT-/GTTTTT 1 -- int10--------
    rs348441251,2
    C--12190710(+) AAAAA-/A/AAA 
            
    CACTT
    4 -- int1 cds11NA 2
    rs714309821,2
    C--12258782(+) AGATA-/TG    
       
    /TGTG
    TGTGT
    2 -- int11NA 2
    rs351088541,2
    C--12270476(+) TGAGT-/A/TAAGGT 2 -- int11NA 2
    rs339400901,2
    C--12313190(+) GAATA-/GATGAG 3 -- int10--------
    rs346456521,2
    C--12336739(+) TTTTT-/T/TT  
            
    GAGAC
    3 -- int11NA 2
    rs339719631,2
    C--12347342(+) AAAAA-/TTTACA 3 -- int10--------
    rs1483419471,2
    C--12390043(+) ACCTC-/AAAATGT 3 -- int10--------

    HapMap Linkage Disequilibrium report for NUBPL (31959162 - 32209162 bp, first 250kb of NUBPL)

    Structural Variations
         Database of Genomic Variants (DGV) 10/16 variations for NUBPL (see all 16):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2668030CNV Deletion23128226
    esv2672738CNV Deletion23128226
    esv2662062CNV Deletion23128226
    esv2678410CNV Deletion23128226
    esv2663509CNV Deletion23128226
    esv271124CNV Insertion20981092
    nsv456199CNV Loss19166990
    dgv130n21CNV Loss19592680
    nsv520783CNV Loss19592680
    nsv521541CNV Loss19592680


    Human Gene Mutation Database (HGMD): NUBPL
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613621   
    OMIM disorders: 252010  
    UniProtKB/Swiss-Prot: NUBPL_HUMAN, Q8TB37
  • Mitochondrial complex I deficiency (MT-C1D) [MIM:252010]: A disorder of the mitochondrial respiratory
    chain that causes a wide range of clinical manifestations from lethal neonatal disease to adult-onset
    neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific
    encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and
    some forms of Parkinson disease. Note=The disease is caused by mutations affecting the gene represented in this
    entry

  • 12 diseases for NUBPL:    About MalaCards
    acute t cell leukemia    mitochondrial complex i deficiency    leber hereditary optic neuropathy    leukodystrophy
    t-cell leukemia    neuropathy    myopathy    liver disease
    parkinson's disease    tuberculosis    schizophrenia    leukemia


    NUBPL for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): NUBPL
    Human Genome Epidemiology (HuGE) Navigator: NUBPL (2 documents)

    Export disorders for NUBPL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NUBPL gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with NUBPL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    2. High-throughput, pooled sequencing identifies mutatio ns in NUBPL and FOXRED1 in human complex I deficiency. (PubMed id 20818383)1, 2 Calvo S.E....Mootha V.K. (2010)
    3. Human ind1, an iron-sulfur cluster assembly factor fo r respiratory complex I. (PubMed id 19752196)1, 2 Sheftel A.D....Lill R. (2009)
    4. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PubMed id 19010793)1, 4 Baranzini S.E....Oksenberg J.R. (2008)
    5. Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia. (PubMed id 18521091)1, 4 Volpi S....Lavedan C. (2008)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. NUBPL mutations in patients with complex I deficiency and a distinct MRI pattern. (PubMed id 23553477)1 Kevelam S.H....van der Knaap M.S. (2013)
    9. Next generation sequencing in molecular diagnosis: NUBPL mutations highlight the challenges of variant detection and interpretation. (PubMed id 22072591)2 Tucker E.J....Thorburn D.R. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80224 HGNC: 20278 AceView: C14orf127 Ensembl:ENSG00000151413 euGenes: HUgn80224
    ECgene: NUBPL H-InvDB: NUBPL

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NUBPL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NUBPL gene:
    Search GeneIP for patents involving NUBPL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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