Aliases for NUBP1 Gene
External Ids for NUBP1 Gene
Previous HGNC Symbols for NUBP1 Gene
Previous GeneCards Identifiers for NUBP1 Gene
NUBP1 is a member of the NUBP/MRP subfamily of ATP-binding proteins (Nakashima et al., 1999 [PubMed 10486206]).[supplied by OMIM, Mar 2008]
GeneCards Summary for NUBP1 Gene
NUBP1 (Nucleotide Binding Protein 1) is a Protein Coding gene. Among its related pathways are Metabolism and Cytosolic Iron-sulfur Cluster Assembly. GO annotations related to this gene include nucleotide binding and 4 iron, 4 sulfur cluster binding. An important paralog of this gene is NUBPL.
UniProtKB/Swiss-Prot for NUBP1 Gene
Implicated in the regulation of centrosome duplication (By similarity). Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.