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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NTNG1 Gene

protein-coding   GIFtS: 59
GCID: GC01P107682

Netrin G1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Netrin G11 2     YLSR5712
Netrin G1f1 2     Axon Guidance Molecule2
KIAA09763 5     Laminet 12
LMNT13 5     laminet-12
Netrin-G11     netrin-G12
Lmnt12     Laminet-13

External Ids:    HGNC: 233191   Entrez Gene: 228542   Ensembl: ENSG000001626317   OMIM: 6088185   UniProtKB: Q9Y2I23   

Export aliases for NTNG1 gene to outside databases

Previous GC identifers: GC00U990862 GC09P128391 GC01P107038 GC01P107395 GC01P107484 GC01P105628


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NTNG1 Gene:
Netrin G1 (NTNG1) belongs to a conserved family of proteins that act as axon guidance cues during vertebrate
nervous system development (Nakashiba et al., 2000 (PubMed 10964959)).(supplied by OMIM, Mar 2008)

GeneCards Summary for NTNG1 Gene: 
NTNG1 (netrin G1) is a protein-coding gene. Diseases associated with NTNG1 include atypical rett syndrome, and rett syndrome. GO annotations related to this gene include protein binding. An important paralog of this gene is LAMC1.

UniProtKB/Swiss-Prot: NTNG1_HUMAN, Q9Y2I2
Function: Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular
and synaptic levels. Promotes neurite outgrowth of both axons and dendrites

Gene Wiki entry for NTNG1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NTNG1 gene promoter:
         p53   NRSF form 1   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNTNG1 promoter sequence
   Search SABiosciences Chromatin IP Primers for NTNG1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NTNG1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p13.3   Ensembl cytogenetic band:  1p13.3   HGNC cytogenetic band: 1p13.2-p13.1

NTNG1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NTNG1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P107682:  view genomic region     (about GC identifiers)

Start:
107,682,629 bp from pter      End:
108,026,080 bp from pter
Size:
343,452 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NTNG1_HUMAN, Q9Y2I2 (See protein sequence)
Recommended Name: Netrin-G1 precursor  
Size: 539 amino acids; 60541 Da
Subunit: Interacts with NGL1
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side
Sequence caution: Sequence=BAA76820.2; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for NTNG1:
3ZYJ (3D)    
Secondary accessions: Q5VU86 Q5VU87 Q5VU89 Q5VU90 Q5VU91 Q7Z2Y3 Q8N633
Alternative splicing: 6 isoforms:  Q9Y2I2-3   Q9Y2I2-2   Q9Y2I2-1   Q9Y2I2-4   Q9Y2I2-5   Q9Y2I2-6   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NTNG1: NX_Q9Y2I2

Explore proteomics data for NTNG1 at MOPED 

Post-translational modifications:

  • UniProtKB: N-glycosylated (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y2I2

  • NTNG1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NTNG1 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_055732.2  NP_001106697.1  NP_001106699.1  

    ENSEMBL proteins: 
     ENSP00000359091   ENSP00000359085   ENSP00000359084   ENSP00000359083   ENSP00000359082  
     ENSP00000359090   ENSP00000359088   ENSP00000440561   ENSP00000359078   ENSP00000359089  
     ENSP00000359087  

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    Browse Sino Biological Cell Lysates 
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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane ----
    GO:0046658anchored to plasma membrane ISS--

    NTNG1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    NTN: Netrins

    4 InterPro protein domains:
     IPR000742 EG-like_dom
     IPR008211 Laminin_N
     IPR013032 EGF-like_CS
     IPR002049 EGF_laminin

    Graphical View of Domain Structure for InterPro Entry Q9Y2I2

    ProtoNet protein and cluster: Q9Y2I2

    1 Blocks protein domain: IPB006210 Type I EGF

    UniProtKB/Swiss-Prot: NTNG1_HUMAN, Q9Y2I2
    Domain: The laminin N-terminal domain mediates 1:1 binding to NGL ligand with sub-micromolar affinity. Three
    NGL-binding loops mediate discrimination for LRRC4C/NGL1 among other NGLs by binding specifically to its LRR
    repeats. This specificity drives the sorting of a mixed population of molecules into discrete cell surface
    subdomains
    Similarity: Contains 3 laminin EGF-like domains
    Similarity: Contains 1 laminin N-terminal domain


    NTNG1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NTNG1_HUMAN, Q9Y2I2
    Function: Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular
    and synaptic levels. Promotes neurite outgrowth of both axons and dendrites

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI14595443
         
    NTNG1 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ntng1):
     mortality/aging  nervous system 

    NTNG1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NTNG1 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NTNG1 
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    SwitchGear 3'UTR luciferase reporter plasmidNTNG1 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NTNG1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Cell adhesion molecules (CAMs)
    Cell adhesion molecules (CAMs)
    2Axon guidance
    Axon guidance

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    2         Kegg Pathways  (Kegg details for NTNG1):
        Axon guidance
    Cell adhesion molecules (CAMs)


    NTNG1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NTNG1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for NTNG1 (Q9Y2I22, 3 ENSP000003590854) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LRRC4CQ9HCJ22, 3, ENSP000002781984MINT-8301036 MINT-8301082 MINT-8300711 MINT-8300986 I2D: score=2 STRING: ENSP00000278198
    LRRC4Q9HBW12MINT-8301004 MINT-8301057
    SLC25A24ENSP000002641284STRING: ENSP00000264128
    EWSR1ENSP000003810314STRING: ENSP00000381031
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007409axonogenesis ISS--

    NTNG1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NTNG1

    Search CenterWatch for drugs/clinical trials and news about NTNG1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NTNG1 gene (3 alternative transcripts): 
    NM_014917.2  NM_001113226.1  NM_001113228.1  

    Unigene Cluster for NTNG1:

    Netrin G1
    Hs.732535  [show with all ESTs]
    Unigene Representative Sequence: AB023193
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370074(uc009wem.3) ENST00000370068(uc001dvi.3 uc001dve.3 uc009wek.3)
    ENST00000294649(uc001dvd.1) ENST00000370067(uc001dvg.3) ENST00000462149
    ENST00000370076 ENST00000370066 ENST00000370065 ENST00000477948 ENST00000370073(uc001dvh.4 uc010out.2)
    ENST00000370071(uc001dvf.4 uc001dvc.4) ENST00000542803 ENST00000370061
    ENST00000370072 ENST00000370070

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    Additional mRNA sequence: 

    AB023193.1 AK296533.1 AK297659.1 AY358365.1 AY764260.1 AY764261.1 AY764262.1 AY764263.1 
    AY764264.1 AY764265.1 AY764266.1 AY764267.1 AY781194.1 BC030220.1 BX538348.1 

    6 DOTS entries:

    DT.433424  DT.40112231  DT.40191199  DT.121364449  DT.436509  DT.454290 

    24/51 AceView cDNA sequences (see all 51):

    BX105933 AA422028 AW085292 AI140857 AI435585 BX538348 BU728093 AW241931 
    CR594836 BE699190 BC030220 CK299898 CA395310 BM983914 AI580385 BI918346 
    BP376410 BP360442 AY358365 BQ876409 AI858128 CB854263 AB023193 AI742127 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NTNG1 expression in normal human tissues (normalized intensities)      NTNG1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NTNG1 Expression
    About this image


    NTNG1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/14 selected tissues (see all 14) fully expand
     
     Cartilage (Muscoskeletal System)    fully expand to see all 4 entries
             Intervertebral Disc Annulus Fibrosus Cells Thoracic Intervertebral Disc
     
     Fibroblast
             Human Villous Mesenchymal Fibroblasts (HVMF)   
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Human Renal Mesangial Cells (HRMC)   
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Mandibular Process
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Pre-Granulosa Cells Primordial Follicle

    See NTNG1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NTNG1

    SOURCE GeneReport for Unigene cluster: Hs.732535

    UniProtKB/Swiss-Prot: NTNG1_HUMAN, Q9Y2I2
    Tissue specificity: Highly expressed in the thalamus, with very low expression, if any, in other tissues

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for NTNG1 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ntng11 , 5 netrin G11, 5 92.15(n)1
    96.47(a)1
      3 (48.47 cM)5
    808831  NM_030699.21  NP_109624.11 
     1097800405 
    chicken
    (Gallus gallus)
    Aves NTNG11 netrin G1 77.28(n)
    80.25(a)
      424336  XM_001231446.2  XP_001231447.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    NTNG16
    (see all 3)
    Uncharacterized protein
    (see all 3)

    86(a)
    (see all 3)
    possible ortholog
    possible ortholog
    (see all 3)
    1(192610699-192634229)
    4(83659320-83659949)
    zebrafish
    (Danio rerio)
    Actinopterygii ntng11 netrin G1 64.43(n)
    65.65(a)
      569075  XM_692438.5  XP_697530.5 
    fruit fly
    (Drosophila melanogaster)
    Insecta wb6
    wing blister
    4(a)
    1 → many
    2L(14263027-14328262)


    ENSEMBL Gene Tree for NTNG1 (if available)
    TreeFam Gene Tree for NTNG1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NTNG1 gene
    LAMC12  LAMC22  NTN32  NTN42  LAMB32  NTN52  LAMC32  NTN12  
    USH2A2  NTNG22  LAMB42  LAMB22  LAMB12  
    5 SIMAP similar genes for NTNG1 using alignment to 14 protein entries:     NTNG1_HUMAN (see all proteins):
    NTNG2    VWDE    NELL1    NTN1    NOTCH3

    NTNG1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6669 SNPs in NTNG1 are shown (see all 6669)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1148723071,2
    C,F--107680699(+) AAGCTG/CGTTTA 2 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1403650921,2
    C--107680775(+) CCTTAC/TCACCT 3 -- us2k10--------
    rs1812230681,2
    --107680792(+) TGCTGA/GAGGAG 3 -- us2k10--------
    rs1157502871,2
    C,F--107681070(+) TGATAC/TAGGAA 3 -- us2k11Minor allele frequency- T:0.01WA 118
    rs45422381,2
    H--107681102(+) CAAGAT/CTTTGA 3 -- us2k14Minor allele frequency- C:0.00NS EA 420
    rs1435521261,2
    C--107681166(+) GTATAC/TTCCAG 3 -- us2k10--------
    rs1140898751,2
    C,F--107681202(+) GATTTA/GTTTTA 3 -- us2k11Minor allele frequency- G:0.01NA 120
    rs127508681,2
    C,H--107681314(+) TGAGAA/CCTGTC 3 -- us2k14Minor allele frequency- C:0.00NS EA 420
    rs1853663421,2
    --107681329(+) TTTCAA/GGATCT 3 -- us2k10--------
    rs127299091,2
    H--107681364(+) AGAAGG/CCCACT 3 -- us2k14Minor allele frequency- C:0.00NS EA 418

    HapMap Linkage Disequilibrium report for NTNG1 (107682629 - 107932629 bp, first 250kb of NTNG1)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for NTNG1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2678975CNV Deletion23128226
    esv2676966CNV Deletion23128226
    esv2674592CNV Deletion23128226
    nsv521184CNV Loss19592680
    nsv508033CNV Loss20534489
    nsv830982CNV Gain17160897
    nsv830993CNV Gain17160897
    essv19382CNV CNV17122850
    essv24194CNV CNV17122850
    dgv82e1CNV Complex17122850


    Human Gene Mutation Database (HGMD): NTNG1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NTNG1
    DNA2.0 Custom Variant and Variant Library Synthesis for NTNG1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608818    OMIM disorders: --

    8 diseases for NTNG1:    About MalaCards
    atypical rett syndrome    rett syndrome    anorexia nervosa    bipolar disorder
    parkinson's disease    systemic lupus erythematosus    lupus erythematosus    schizophrenia

    1 disease from the University of Copenhagen DISEASES database for NTNG1:
    Rett syndrome

    NTNG1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): NTNG1
    Human Genome Epidemiology (HuGE) Navigator: NTNG1 (13 documents)

    Export disorders for NTNG1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NTNG1 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with NTNG1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human netrin-G1 isoforms show evidence of differential expression. (PubMed id 15901489)1, 2, 9 Meerabux J.M....Yoshikawa T. (2005)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. A genome-wide association study on common SNPs and ra re CNVs in anorexia nervosa. (PubMed id 21079607)1, 4 Wang K....Hakonarson H. (2010)
    4. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    5. Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1, 4 Trynka G....Wijmenga C. (2009)
    6. Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease. (PubMed id 18628988)1, 4 Li Y....Hadjigeorgiou G. (2008)
    7. Association of polymorphisms in the haplotype block spanning the alternatively spliced exons of the NTNG1 gene at 1p13.3 with schizophrenia in Japanese populations. (PubMed id 18384956)1, 4 Ohtsuki T....Arinami T. (2008)
    8. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    9. Case-control association study of human netrin G1 gene in Japanese schizophrenia. (PubMed id 15508520)1, 4 Fukasawa M....Yoshikawa T. (2004)
    10. Fc receptor gamma subunit polymorphisms and systemic lupus erythematosus. (PubMed id 15494819)1, 4 Alansari A....Hajeer A.H. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 22854 HGNC: 23319 AceView: NTNG1 Ensembl:ENSG00000162631 euGenes: HUgn22854
    ECgene: NTNG1 Kegg: 22854 H-InvDB: NTNG1

    (According to HUGE)
    About This Section
    HUGE: KIAA0976

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NTNG1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NTNG1 gene:
    Search GeneIP for patents involving NTNG1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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