Free for academic non-profit institutions. Other users need a Commercial license

Aliases for NTN5 Gene

Aliases for NTN5 Gene

  • Netrin 5 2 3
  • Netrin-1-Like Protein 3 4
  • Netrin-5 2 3
  • CNB2 6

External Ids for NTN5 Gene

Summaries for NTN5 Gene

GeneCards Summary for NTN5 Gene

NTN5 (Netrin 5) is a Protein Coding gene. An important paralog of this gene is NTN3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NTN5 Gene

Genomics for NTN5 Gene

Genomic Location for NTN5 Gene

Start:
48,661,407 bp from pter
End:
48,673,081 bp from pter
Size:
11,675 bases
Orientation:
Minus strand

Genomic View for NTN5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NTN5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NTN5 Gene

Regulatory Elements for NTN5 Gene

Proteins for NTN5 Gene

  • Protein details for NTN5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WTR8-NET5_HUMAN
    Recommended name:
    Netrin-5
    Protein Accession:
    Q8WTR8
    Secondary Accessions:
    • Q8N4X9
    • Q8WU63

    Protein attributes for NTN5 Gene

    Size:
    489 amino acids
    Molecular mass:
    53174 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for NTN5 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for NTN5 Gene

Proteomics data for NTN5 Gene at MOPED

Post-translational modifications for NTN5 Gene

Other Protein References for NTN5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NTN5 Gene

Domains for NTN5 Gene

Gene Families for NTN5 Gene

HGNC:

Protein Domains for NTN5 Gene

UniProtKB/Swiss-Prot:

NET5_HUMAN
Domain:
  • Contains 3 laminin EGF-like domains.:
    • Q8WTR8
  • Contains 1 NTR domain.:
    • Q8WTR8
genes like me logo Genes that share domains with NTN5: view

Function for NTN5 Gene

Gene Ontology (GO) - Molecular Function for NTN5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with NTN5: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NTN5 Gene

Localization for NTN5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NTN5 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NTN5 Gene COMPARTMENTS Subcellular localization image for NTN5 gene
Compartment Confidence
extracellular 3

Gene Ontology (GO) - Cellular Components for NTN5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with NTN5: view

Pathways for NTN5 Gene

SuperPathways for NTN5 Gene

No Data Available

Interacting Proteins for NTN5 Gene

Gene Ontology (GO) - Biological Process for NTN5 Gene

None

No data available for Pathways by source for NTN5 Gene

Transcripts for NTN5 Gene

mRNA/cDNA for NTN5 Gene

Unigene Clusters for NTN5 Gene

Netrin 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for NTN5 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b
SP1: - -
SP2: - - -
SP3:
SP4:

Relevant External Links for NTN5 Gene

GeneLoc Exon Structure for
NTN5
ECgene alternative splicing isoforms for
NTN5

Expression for NTN5 Gene

mRNA expression in normal human tissues for NTN5 Gene

mRNA differential expression in normal tissues according to GTEx for NTN5 Gene

This gene is overexpressed in Pituitary (5.9).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for NTN5 Gene

SOURCE GeneReport for Unigene cluster for NTN5 Gene Hs.326217

genes like me logo Genes that share expressions with NTN5: view

Orthologs for NTN5 Gene

This gene was present in the common ancestor of animals.

Orthologs for NTN5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NTN5 36
  • 99.32 (n)
  • 99.18 (a)
NTN5 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia NTN5 36
  • 84.9 (n)
  • 85.04 (a)
NTN5 37
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia NTN5 37
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ntn5 36
  • 79.47 (n)
  • 77.8 (a)
Ntn5 16
Ntn5 37
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia NTN5 37
  • 70 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia NTN5 37
  • 59 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ntn5 36
  • 78.46 (n)
  • 74.35 (a)
chicken
(Gallus gallus)
Aves -- 37
  • 8 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia NTN5 37
  • 37 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii NTN5 37
  • 22 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta NetA 37
  • 25 (a)
ManyToMany
NetB 37
  • 22 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea unc-6 37
  • 29 (a)
OneToMany
Species with no ortholog for NTN5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for NTN5 Gene

ENSEMBL:
Gene Tree for NTN5 (if available)
TreeFam:
Gene Tree for NTN5 (if available)

Paralogs for NTN5 Gene

Paralogs for NTN5 Gene

Selected SIMAP similar genes for NTN5 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with NTN5: view

Variants for NTN5 Gene

Structural Variations from Database of Genomic Variants (DGV) for NTN5 Gene

Variant ID Type Subtype PubMed ID
nsv9739 CNV Gain+Loss 18304495
dgv3966n71 CNV Loss 21882294
dgv3967n71 CNV Loss 21882294
nsv912235 CNV Loss 21882294
nsv912236 CNV Gain 21882294
esv2718679 CNV Deletion 23290073
esv2718680 CNV Deletion 23290073
esv2718681 CNV Deletion 23290073

Relevant External Links for NTN5 Gene

HapMap Linkage Disequilibrium report
NTN5

No data available for Sequence variations from dbSNP and Humsavar for NTN5 Gene

Disorders for NTN5 Gene

No disorders were found for NTN5 Gene.

No data available for UniProtKB/Swiss-Prot for NTN5 Gene

Publications for NTN5 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PMID: 21926972) (Nat. Genet. 2011) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for NTN5 Gene

Sources for NTN5 Gene

Back to Top

Content