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NTMT1 Gene

protein-coding   GIFtS: 42
GCID: GC09P132372

N-Terminal Xaa-Pro-Lys N-Methyltransferase 1

(Previous names: chromosome 9 open reading frame 32, methyltransferase like...)
(Previous symbols: C9orf32, METTL11A)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
N-Terminal Xaa-Pro-Lys N-Methyltransferase 11 2     X-Pro-Lys N-Terminal Protein Methyltransferase 1A2 3
C9orf321 2 3     Chromosome 9 Open Reading Frame 321
METTL11A1 2 3     Methyltransferase Like 11A1
Alpha N-Terminal Protein Methyltransferase 1A2 3     AD-0032
Methyltransferase-Like Protein 11A2 3     HOMT1A2
NRMT2 3     EC 2.1.1.2443
NTM1A2 3     NRMT13
N-Terminal RCC1 Methyltransferase2 3     

External Ids:    HGNC: 233731   Entrez Gene: 289892   Ensembl: ENSG000001483357   OMIM: 6135605   UniProtKB: Q9BV863   

Export aliases for NTMT1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NTMT1 Gene:
The METTL11A gene encodes an N-terminal methyltransferase for the RAN (MIM 601179) guanine nucleotide exchange
factor regulator of chromosome condensation 1 (RCC1; MIM 179710). METTL11A enzyme alpha-N-methylates other
protein targets such as SET (MIM 600960) and RB (MIM 180200).(supplied by OMIM, Nov 2010)

GeneCards Summary for NTMT1 Gene:
NTMT1 (N-terminal Xaa-Pro-Lys N-methyltransferase 1) is a protein-coding gene. Diseases associated with NTMT1 include retinoblastoma, and malaria. GO annotations related to this gene include protein methyltransferase activity. An important paralog of this gene is METTL11B.

UniProtKB/Swiss-Prot: NTM1A_HUMAN, Q9BV86
Function: Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the
N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or
tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or
di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated
monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET.
Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for NTMT1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNTMT1 promoter sequence
   Search Chromatin IP Primers for NTMT1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NTMT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.11   Ensembl cytogenetic band:  9q34.11   HGNC cytogenetic band: 9q34.2

NTMT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NTMT1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P132372:  view genomic region     (about GC identifiers)

Start:
132,371,163 bp from pter      End:
132,398,209 bp from pter
Size:
27,047 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NTM1A_HUMAN, Q9BV86 (See protein sequence)
Recommended Name: N-terminal Xaa-Pro-Lys N-methyltransferase 1  
Size: 223 amino acids; 25387 Da
1 PDB 3D structure from and Proteopedia for NTMT1:
2EX4 (3D)    
Secondary accessions: A8K4J2 A8K8G7 Q5SZB9 Q9UI28
Alternative splicing: 2 isoforms:  Q9BV86-1   Q9BV86-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NTMT1: NX_Q9BV86

Explore proteomics data for NTMT1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys10, Lys59, Lys101
  • Modification sites at PhosphoSitePlus

  • See NTMT1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (9 alternative transcripts): 
    NP_001273725.1  NP_001273726.1  NP_001273727.1  NP_001273728.1  NP_001273729.1  NP_001273730.1  NP_001273731.1  NP_001273732.1  
    NP_054783.2  

    ENSEMBL proteins: 
     ENSP00000361564   ENSP00000361561   ENSP00000473916   ENSP00000474445   ENSP00000473900  
     ENSP00000361559   ENSP00000361558  

    NTMT1 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR008576 DUF858_MeTrfase_lik

    Graphical View of Domain Structure for InterPro Entry Q9BV86

    ProtoNet protein and cluster: Q9BV86

    1 Blocks protein domain: IPB013216 Methyltransferase type 11

    UniProtKB/Swiss-Prot: NTM1A_HUMAN, Q9BV86
    Similarity: Belongs to the methyltransferase superfamily. NTM1 family


    NTMT1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NTM1A_HUMAN, Q9BV86
    Function: Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the
    N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or
    tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or
    di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated
    monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET.
    Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1
    Catalytic activity: 3 S-adenosyl-L-methionine + N-terminal-(A,S)PK-[protein] = 3 S-adenosyl-L-homocysteine +
    N-terminal-N,N,N-trimethyl-N-(A,S)PK-[protein]
    Catalytic activity: 2 S-adenosyl-L-methionine + N-terminal-PPK-[protein] = 2 S-adenosyl-L-homocysteine +
    N-terminal-N,N-dimethyl-N-PPK-[protein]

         Enzyme Number (IUBMB): EC 2.1.1.2441

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008168methyltransferase activity ----
    GO:0008171O-methyltransferase activity ----
    GO:0008276protein methyltransferase activity IDA--
         
    NTMT1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NTMT1
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    miRNA
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    miRTarBase miRNAs that target NTMT1:
    hsa-mir-124-3p (MIRT022881), hsa-mir-10a-5p (MIRT047648)

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    Search for qRT-PCR Assays for microRNAs that regulate NTMT1
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    Predesigned siRNA for gene silencing in human, mouse, rat NTMT1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NTMT1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NTM1A_HUMAN, Q9BV86: Nucleus. Note=Predominantly nuclear

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--

    NTMT1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NTMT1
    Interactions:

        Search GeneGlobe Interaction Network for NTMT1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NTMT1 (Q9BV861, 3 ENSP000003615584) via UniProtKB, MINT, STRING, and/or I2D (see all 64)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL9P329693, ENSP000003460224I2D: score=1 STRING: ENSP00000346022
    RPL9P7P329693I2D: score=1 
    RPL9P8P329693I2D: score=1 
    RPL9P9P329693I2D: score=1 
    DIS3Q9Y2L11, 3, ENSP000003669974EBI-373016,EBI-373539 I2D: score=1 STRING: ENSP00000366997
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007051spindle organization IMP--
    GO:0007059chromosome segregation IMP--
    GO:0008152metabolic process ----
    GO:0018012N-terminal peptidyl-alanine trimethylation IEA--
    GO:0018016N-terminal peptidyl-proline dimethylation IDA--

    NTMT1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NTMT1 (NTM1A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NTMT1 gene (9 alternative transcripts): 
    NM_001286796.1  NM_001286797.1  NM_001286798.1  NM_001286799.1  NM_001286800.1  NM_001286801.1  NM_001286802.1  NM_001286803.1  
    NM_014064.3  

    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372486 ENST00000372483(uc004byd.1 uc011mbs.1 uc010myw.1)
    ENST00000481189 ENST00000459968 ENST00000482347 ENST00000372481 ENST00000372480
    ENST00000486391
    miRNA
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat NTMT1
      QuantiFast Probe-based Assays in human, mouse, rat NTMT1

    Selected AceView cDNA sequences (see all 158):

    BM927413 AJ572109 F29109 BI083998 AW157326 BQ012313 BF989706 BM554138 
    BC001396 BQ689083 BC033234 BU186604 BQ940794 AA084995 BU682643 BG180464 
    BM887977 BM781855 D12039 BU542149 BM914694 BM916567 BM909502 AA494415 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NTMT1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c
    SP1:              -     -                 -                     
    SP2:              -     -           -     -                     
    SP3:                    -                 -                     
    SP4:              -     -                                       
    SP5:                                                            


    ECgene alternative splicing isoforms for NTMT1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NTMT1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NTMT1 Expression
    About this image

    NTMT1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NTMT1 Protein Expression
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NTMT1 gene from Selected species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ntmt11 , 5 methyltransferase like 11A5
    N-terminal Xaa-Pro-Lys N-methyltransferase 11
    89.99(n)1
    94.17(a)1
      2 (21.74 cM)5
    666171  NM_170592.21  NP_733480.11 
     308078265 
    chicken
    (Gallus gallus)
    Aves METTL11A1 methyltransferase like 11A 79.82(n)
    82.96(a)
      425539  NM_001277690.1  NP_001264619.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.253482 Xenopus laevis transcribed sequence with moderate similarity more 72.69(n)    BX848741.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570453622   -- 72.34(n)    57045362 
    fruit fly
    (Drosophila melanogaster)
    Insecta Ntmt1 N-terminal methyltransferase 50.62(n)
    43.06(a)
      36022  NM_136684.3  NP_610528.1 
    worm
    (Caenorhabditis elegans)
    Secernentea homt-11 homt-1 45.51(n)
    40.18(a)
      171590  NM_058260.4  NP_490660.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TAE1(YBR261C)4
    TAE11
    AdoMet-dependent proline methyltransferase; catalyzes more4
    TAE11
    47.58(n)1
    39.55(a)1
      2(735530-734832)4
    8525641, 4  NP_009820.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G444501 AT5G44450 48.13(n)
    43.93(a)
      834472  NM_123812.4  NP_199258.3 
    rice
    (Oryza sativa)
    Liliopsida Os03g07809001 Os03g0780900 49.84(n)
    42.38(a)
      4334312  NM_001057989.1  NP_001051454.1 


    ENSEMBL Gene Tree for NTMT1 (if available)
    TreeFam Gene Tree for NTMT1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NTMT1 gene
    METTL11B2  
    1 SIMAP similar gene for NTMT1 using alignment to 4 protein entries:     NTM1A_HUMAN (see all proteins):
    METTL11B

    NTMT1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NTMT1 (see all 201)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs753651901,2
    C--132386442(+) CTATGC/TGCTAG 1 -- us2k10--------
    rs1463311531,2
    --132386487(+) TCAGGG/TAGCCG 1 -- us2k10--------
    rs1842028741,2
    --132386516(+) TTGGAA/GCGTGG 1 -- us2k10--------
    rs1888282511,2
    --132386525(+) GGCTGC/TGGGGA 1 -- us2k10--------
    rs1815356261,2
    --132386539(+) GGCTTA/GCTCTT 1 -- us2k10--------
    rs1853117261,2
    --132386583(+) TAGGCA/CTACAG 1 -- us2k10--------
    rs1905091141,2
    --132386726(+) CAGTTA/GTGACC 1 -- us2k10--------
    rs45094421,2
    C,F,H--132386835(+) TTTCAG/ACACAT 1 -- us2k132Minor allele frequency- A:0.06NA NS EA WA CSA 2906
    rs1382429641,2
    --132386844(+) ATTTAA/GAGCAA 1 -- us2k10--------
    rs70376861,2
    C,F,H--132386966(+) agcaaT/Cggcgc 1 -- us2k14Minor allele frequency- C:0.00NS EA 416

    HapMap Linkage Disequilibrium report for NTMT1 (132371163 - 132398209 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NTMT1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NTMT1
    DNA2.0 Custom Variant and Variant Library Synthesis for NTMT1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613560    OMIM disorders: --

    2 diseases for NTMT1:    
    About MalaCards
    retinoblastoma    malaria


    NTMT1 for disorders           About GeneDecksing


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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NTMT1 gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with NTMT1)
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    1. Identification of protein N-terminal methyltransferases in yeast and humans. (PubMed id 20481588)1, 2, 3 Webb K.J.... Clarke S.G. (Biochemistry 2010)
    2. NRMT is an alpha-N-methyltransferase that methylates RCC1 and retinoblastoma protein. (PubMed id 20668449)1, 2 Tooley C.E.... Macara I.G. (Nature 2010)
    3. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    6. NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1. (PubMed id 24090352)2 Petkowski J.J.... Schaner Tooley C.E. (Biochem. J. 2013)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Substrate specificity of mammalian N-terminal I+-amino methyltransferase NRMT. (PubMed id 22769851)1 Petkowski J.J....Macara I.G. (Biochemistry 2012)
    9. Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-I+-acetylation features. (PubMed id 22223895)2 Bienvenut W.V....Giglione C. (amp 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 28989 HGNC: 23373 AceView: AD-003 Ensembl:ENSG00000148335 euGenes: HUgn28989
    ECgene: NTMT1 H-InvDB: NTMT1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NTMT1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NTMT1 gene:
    Search GeneIP for patents involving NTMT1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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