NTHL1 Gene
protein-coding GIFtS: 65
GCID: GC16M002089
|
|
nth endonuclease III-like 1 (E. coli)(Previous name: nth (E.coli endonuclease III)-like 1 )
| |
Aliases
for NTHL1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Nth Endonuclease III-Like 1 (E. Coli)1 2 | | OCTS31 2 3 5 | | NTH11 2 3 | | Nth (E.Coli Endonuclease III)-Like 11 | | Endonuclease III-Like Protein 12 | | EC 4.2.99.183 |
Export aliases for NTHL1 gene to outside databasesPrevious GC identifers: GC16M002107 GC16M002030 GC16M002031 GC16M002032 GC16M002014 |
Summaries
for NTHL1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NTHL1:
The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E.coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues andhas apurinic/apyrimidinic lyase activity. (provided by RefSeq, Oct 2008)
UniProtKB/Swiss-Prot: NTHL1_HUMAN, P78549Function: Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incisesdamaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for therepair of both oxidative DNA damage and spontaneous mutagenic lesions
Gene Wiki entry for NTHL1
|
Genomic Views
for NTHL1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NTHL1 gene promoter:
NF-1 p53 STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for NTHL1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NTHL1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3NTHL1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M002089: view genomic region
(about GC identifiers)
Start:
|
2,089,816 bp from pter |
End:
|
2,097,867 bp from pter |
Size:
|
8,052 bases |
Orientation:
|
minus strand |
|
Proteins
for NTHL1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NTHL1_HUMAN, P78549 (See
protein sequence)Recommended Name: Endonuclease III-like protein 1 Size: 312 amino acids; 34390 Da
Cofactor: Binds 1 4Fe-4S cluster. The cluster is not important for the catalytic activity, but is probably involved inthe proper positioning of the enzyme along the DNA strand
Subcellular location: Nucleus
Developmental stage: Expression levels are regulated during the cell cycle with increased levels during early and midS-phase
Caution: It is uncertain whether Met-1, Met-9 or Met-16 is the initiator
Sequence caution: Sequence=AAC51136.1; Type=Erroneous initiation; Sequence=AAH03014.1; Type=Erroneous initiation;Sequence=BAA19413.1; Type=Erroneous initiation; Sequence=BAA32695.1; Type=Erroneous initiation;
Secondary accessions: Q1MVR1 Q99566 Q99794 Q9BPX2Explore the universe of human proteins at neXtProt for NTHL1: NX_P78549
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P78549
NTHL1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_002519.1
ENSEMBL proteins: ENSP00000219066 ENSP00000455267 ENSP00000457818 ENSP00000456301 Reactome Protein details: P78549
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
NTHL1 for ontologies About GeneDecksing
NTHL1 Antibody Products:
Assay Products for NTHL1: |
Protein
Domains /
Families
for NTHL1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NTHL1 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry P78549ProtoNet protein and cluster: P78549 2 Blocks protein families: IPB004036 Endonuclease III IPB011257 DNA glycosylase
UniProtKB/Swiss-Prot: NTHL1_HUMAN, P78549Similarity: Belongs to the Nth/MutY family |
Function
for NTHL1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NTHL1_HUMAN, P78549Function: Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incisesdamaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for therepair of both oxidative DNA damage and spontaneous mutagenic lesionsCatalytic activity: The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-eliminationreaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate Genatlas biochemistry entry for NTHL1:nth (E coli endonuclease III)-like 1,34.3 kDa,with lyase activity,involved in the excision of damaged pyrimidines
Enzyme Number (IUBMB): EC 4.2.99.181
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NTHL1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NTHL1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: NTHL1 (NM_002528) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NTHL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NTHL1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NTHL1 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
NTHL1 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for NTHL1:
Animal Models:
Mouse knock-outs for NTHL1: Nthl1tm1Tbor Nthl1tm1Yas
5 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Nthl1):
NTHL1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for NTHL1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Base-Excision Repair, AP Site Formation | | | 2 | Resolution of Abasic Sites (AP sites) | | | 3 | Formation of RNA Pol II elongation complex | | | 4 | Nucleotide Excision Repair | | | 5 | Chks in Checkpoint Regulation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for NTHL1
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for NTHL1
1  GeneGo (Thomson Reuters) Pathway for NTHL1
5/12 
Reactome Pathways for NTHL1 (see all 12)
1 
Kegg Pathway (Kegg details for NTHL1):
NTHL1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NTHL1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/54 Interacting proteins for NTHL1 (P785493 ENSP000002190664) via UniProtKB, MINT, STRING, and/or I2D (see all 54)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
NTHL1 for ontologies About GeneDecksing
|
Drugs & Compounds
for NTHL1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
NTHL1 for compounds About GeneDecksing
 Browse Tocris compounds for NTHL1
2 Novoseek chemical compound relationships for NTHL1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| thymine glycol |
88.6 |
3 |
19414504 (2) |
| oxygen |
4.87 |
1 |
17389588 (1) |
Search CenterWatch for drugs/clinical trials and news about NTHL1
|
Transcripts
for NTHL1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NTHL1 gene: NM_002528.5 Unigene Cluster for NTHL1: Nth endonuclease III-like 1 (E. coli) Hs.66196 [show with all ESTs]Unigene Representative Sequence: BQ06765310 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000219066(uc002col.1) ENST00000561862 ENST00000565406 ENST00000566380
ENST00000562951 ENST00000568513 ENST00000567727 ENST00000561841 ENST00000562120
ENST00000569594
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NTHL1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NTHL1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NTHL1 (NM_002528) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NTHL1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NTHL1 |
Additional cDNA sequence: AB001575.1 AK298247.1 BC000391.2 BC003014.1 U79718.1 U81285.1 Y09687.1 4 DOTS entries: DT.111381 DT.120674915 DT.95275667 DT.91766138 12 AceView cDNA sequences: AB001575 U81285 CR625882 NM_002528 BC000391 CR597616 BC003014 Y09687 U79718 BX444894 BX379864 BE693591
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for NTHL1 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | - | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for NTHL1
|
Expression
for NTHL1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NTHL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTCTGGCCG
About this image
See NTHL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NTHL1
SOURCE GeneReport for Unigene cluster: Hs.66196
UniProtKB/Swiss-Prot: NTHL1_HUMAN, P78549Tissue specificity: Widely expressed with highest levels in heart and lowest levels in lung and liver
SABiosciences Expression via Pathway-Focused PCR Arrays including NTHL1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NTHL1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NTHL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NTHL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NTHL1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NTHL1 |
Orthologs
for NTHL1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for NTHL1 gene from 11/38 species (see all 38) About this table
ENSEMBL Gene Tree for NTHL1 (if available)
TreeFam Gene Tree for NTHL1 (if available) |
Paralogs
for NTHL1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for NTHL1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NTHL1 (2089816 - 2097867 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for NTHL1
2 CNVs: 30000 5329
Human Gene Mutation Database (HGMD): NTHL1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NTHL1 |
|
Disorders
/ Diseases
for NTHL1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NTHL1 for disorders About GeneDecksing
OMIM gene information: 602656
OMIM disorders: --
16  diseases for NTHL1: About MalaCardsgraft versus host disease sclerosing cholangitis primary sclerosing cholangitis tuberous sclerosis
cholangitis chronic lymphocytic leukemia lymphocytic leukemia multiple sclerosis
gastric cancer colorectal cancer leukemia adenoma
pneumonia tuberculosis malaria mycobacterium tuberculosis
2 Novoseek disease relationships for NTHL1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tuberous sclerosis |
45.3 |
2 |
9831664 (1), 8990169 (1) |
| cancer |
6.1 |
1 |
19443904 (1) |
Human Genome Epidemiology (HuGE) Navigator: NTHL1 (8 documents)
Export disorders for NTHL1 gene to outside databases
|
Publications
for NTHL1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NTHL1 gene, integrated from 9 sources (see all 65):
(articles sorted by number of sources associating them with NTHL1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III. (PubMed id 8990169)1, 2, 3, 9 Aspinwall R....Hickson I.D. (1997)
- Cloning and expression of the cDNA encoding the human homologue of the DNA repair enzyme, Escherichia coli endonuclease III. (PubMed id 9045706)1, 2, 3 Hilbert T.P.... Teebor G.W. (1997)
- Genomic structure and sequence of a human homologue (NTHL1/NTH1) of Escherichia coli endonuclease III with those of the adjacent parts of TSC2 and SLC9A3R2 genes. (PubMed id 9831664)1, 2, 9 Imai K.... Seki S. (1998)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Differential intracellular localization of the human and mouse endonuclease III homologs and analysis of the sorting signals. (PubMed id 12531031)1, 2 Ikeda S.... Seki Y. (2002)
- Cell-cycle regulation, intracellular sorting and induced overexpression of the human NTH1 DNA glycosylase involved in removal of formamidopyrimidine residues from DNA. (PubMed id 10882850)1, 2 Luna L.... Seeberg E. (2000)
- Purification and characterization of human NTH1, a homolog of Escherichia coli endonuclease III. Direct identification of Lys-212 as the active nucleophilic residue. (PubMed id 9705289)1, 2 Ikeda S.... Mitra S. (1998)
- Altered expression of the human base excision repair gene NTH1 in gastric cancer. (PubMed id 19414504)1, 9 Goto M....Sugimura H. (2009)
- Inherited predisposition to colorectal adenomas caused by multiple rare alleles of MUTYH but not OGG1, NUDT1, NTH1 or NEIL 1, 2 or 3. (PubMed id 18515411)1, 9 Dallosso A.R....Sampson J.R. (2008)
|
External Searches for NTHL1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NTHL1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NTHL1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NTHL1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for NTHL1 gene:
Search GeneIP for patents involving NTHL1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NTHL1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for NTHL1 | | OriGene shRNA RFP for NTHL1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NTHL1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NTHL1 | | | OriGene Protein Over-expression Lysate for NTHL1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NTHL1 | | OriGene 3'-UTR Clone for NTHL1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NTHL1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NTHL1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NTHL1 | | OriGene Custom Protein Services for NTHL1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NTHL1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NTHL1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NTHL1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NTHL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NTHL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NTHL1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for NTHL1 |
| |  |  |  |  | | | | | | Recombinant Protein for NTHL1 |
|
 |
 |
 |
 | | | NTHL1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NTHL1 |
|  |  |  | | | | ThermoFisher Antibodies for NTHL1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NTHL1 |
|
|
|
|
