Aliases for NTF4 Gene
External Ids for NTF4 Gene
Previous HGNC Symbols for NTF4 Gene
Previous GeneCards Identifiers for NTF4 Gene
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008]
GeneCards Summary for NTF4 Gene
NTF4 (Neurotrophin 4) is a Protein Coding gene. Diseases associated with NTF4 include Glaucoma 1, Open Angle, 1O and Hypochondriasis. Among its related pathways are Activation of cAMP-Dependent PKA and GPCR Pathway. GO annotations related to this gene include receptor binding and neurotrophin p75 receptor binding. An important paralog of this gene is BDNF.
UniProtKB/Swiss-Prot for NTF4 Gene
Target-derived survival factor for peripheral sensory sympathetic neurons.