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NT5DC3 Gene

protein-coding   GIFtS: 50
GCID: GC12M104164

5'-Nucleotidase Domain Containing 3

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
5'-Nucleotidase Domain Containing 31 2     5'-Nucleotidase Domain-Containing Protein 32
TU12B1-TY2 3     EC 3.1.3.-3
TU12B1TY2 5     GRP94-Neighboring Nucleotidase3
GNN3 5     

External Ids:    HGNC: 308261   Entrez Gene: 515592   Ensembl: ENSG000001116967   OMIM: 6110765   UniProtKB: Q86UY83   

Export aliases for NT5DC3 gene to outside databases

Previous GC identifers: GC12M102669 GC12M101226


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NT5DC3 Gene:
NT5DC3 (5'-nucleotidase domain containing 3) is a protein-coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is NT5C2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the NT5DC3 gene promoter:
         HEN1   ISGF-3   POU2F1   POU2F1a   Arnt   RORalpha2   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNT5DC3 promoter sequence
   Search Chromatin IP Primers for NT5DC3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NT5DC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q22-q23.1   Ensembl cytogenetic band:  12q23.3   HGNC cytogenetic band: 12q22-q23.1

NT5DC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NT5DC3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M104164:  view genomic region     (about GC identifiers)

Start:
104,164,231 bp from pter      End:
104,234,975 bp from pter
Size:
70,745 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NT5D3_HUMAN, Q86UY8 (See protein sequence)
Recommended Name: 5'-nucleotidase domain-containing protein 3  
Size: 548 amino acids; 63420 Da
Cofactor: Binds 1 magnesium ion per subunit (By similarity)
Sequence caution: Sequence=BAA92095.1; Type=Erroneous initiation; Sequence=BAA93053.1; Type=Frameshift;
Positions=62;
Secondary accessions: Q9NUM7 Q9P2T2 Q9P2T3
Alternative splicing: 2 isoforms:  Q86UY8-1   Q86UY8-2   

Explore the universe of human proteins at neXtProt for NT5DC3: NX_Q86UY8

Explore proteomics data for NT5DC3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NT5DC3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001026871.1  
    ENSEMBL proteins: 
     ENSP00000413657   ENSP00000376615   ENSP00000399171  

    NT5DC3 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for NT5DC3
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    Novus Biologicals NT5DC3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NT5DC3

     
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    antibodies-online proteins for NT5DC3 

     
    antibodies-online peptides for NT5DC3

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    Abcam antibodies for NT5DC3
    Cloud-Clone Corp. Antibodies for NT5DC3
    ThermoFisher Antibody for NT5DC3
    antibodies-online antibodies for NT5DC3 (4 products) 

    NT5DC3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NT5DC3
    Cloud-Clone Corp. CLIAs for NT5DC3
    Search eBioscience for ELISAs for NT5DC3 
    antibodies-online kits for NT5DC3 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR023214 HAD-like_dom
     IPR008380 HAD-SF_hydro_IG_5-nucl
     IPR016695 Pur_nucleotidase

    Graphical View of Domain Structure for InterPro Entry Q86UY8

    ProtoNet protein and cluster: Q86UY8

    UniProtKB/Swiss-Prot: NT5D3_HUMAN, Q86UY8
    Similarity: Belongs to the 5'(3')-deoxyribonucleotidase family


    Find genes that share domains with NT5DC3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Number (IUBMB): EC 3.1.3.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016787hydrolase activity IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with NT5DC3           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NT5DC3

    miRNA
    Products:
        
    miRTarBase miRNAs that target NT5DC3:
    hsa-mir-335-5p (MIRT018478), hsa-mir-193b-3p (MIRT016515), hsa-mir-92a-3p (MIRT049332), hsa-mir-10a-5p (MIRT047697), hsa-mir-378a-5p (MIRT043963)

    Block miRNA regulation of human, mouse, rat NT5DC3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NT5DC3 (see all 25):
    hsa-miR-485-5p hsa-miR-1271 hsa-miR-515-5p hsa-miR-3142 hsa-miR-23a hsa-miR-3121-3p hsa-miR-330-3p hsa-miR-96
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for NT5DC3
    Predesigned siRNA for gene silencing in human, mouse, rat NT5DC3

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for NT5DC3 (see all 11)
    OriGene ORF clones in mouse, rat for NT5DC3
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    GenScript: all cDNA clones in your preferred vector: NT5DC3 (NM_001031701)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NT5DC3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NT5DC3

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for NT5DC3 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5DC3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    mitochondrion2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0005829cytosol IEA--
    GO:0043235receptor complex IDA--

    Find genes that share ontologies with NT5DC3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NT5DC3
    Interactions:

        Search GeneGlobe Interaction Network for NT5DC3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    Selected Interacting proteins for NT5DC3 (Q86UY83 ENSP000003766154) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000204490P013753I2D: score=1 
    ENSG00000206439P013753I2D: score=1 
    ENSG00000223952P013753I2D: score=1 
    ENSG00000228321P013753I2D: score=1 
    ENSG00000228849P013753I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NT5DC3 (NT5D3)

    1 HMDB Compound for NT5DC3    About this table
    CompoundSynonyms CAS #PubMed Ids
    MagnesiumMagnesium (see all 2)7439-95-4--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NT5DC3 gene (2 alternative transcripts): 
    NM_016575.1  NM_001031701.2  

    Unigene Cluster for NT5DC3:

    5'-nucleotidase domain containing 3
    Hs.48428  [show with all ESTs]
    Unigene Representative Sequence: NM_001031701
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000447799 ENST00000392876(uc010swe.1) ENST00000415849 ENST00000474268
    ENST00000465502
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NT5DC3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NT5DC3 (see all 25):
    hsa-miR-485-5p hsa-miR-1271 hsa-miR-515-5p hsa-miR-3142 hsa-miR-23a hsa-miR-3121-3p hsa-miR-330-3p hsa-miR-96
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for NT5DC3
    Predesigned siRNA for gene silencing in human, mouse, rat NT5DC3
    Clone
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    OriGene clones in human, mouse for NT5DC3 (see all 11)
    OriGene ORF clones in mouse, rat for NT5DC3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NT5DC3 (NM_001031701)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NT5DC3
    Primer
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    OriGene qPCR primer pairs and template standards for NT5DC3
    OriGene qSTAR qPCR primer pairs in human, mouse for NT5DC3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NT5DC3
      QuantiTect SYBR Green Assays in human, mouse, rat NT5DC3
      QuantiFast Probe-based Assays in human, mouse, rat NT5DC3

    Additional mRNA sequence: 

    AB032773.1 AK130442.1 BC052293.1 

    5 DOTS entries:

    DT.416750  DT.101963203  DT.95286617  DT.95300035  DT.121176108 

    Selected AceView cDNA sequences (see all 138):

    AI744176 BC052293 BF593836 BU155544 CD672505 AI865829 BU838097 AI041733 
    BM795871 AJ706163 BM562753 BQ682708 AI800679 BQ684492 AI784548 AW205506 
    BM855976 CA420627 BF476138 CA396370 CA446417 AL138224 AI761233 BM818567 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NT5DC3    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17a · 17b ^ 18 ^ 19
    SP1:        -                       -                                                           -                                             
    SP2:                                                                                                                                          
    SP3:                                -                                                                                                         
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for NT5DC3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NT5DC3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NT5DC3 Expression
    About this image

    NT5DC3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NT5DC3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.48428

    UniProtKB/Swiss-Prot: NT5D3_HUMAN, Q86UY8
    Tissue specificity: Expressed in brain, placenta, skeletal muscle, pancreas, testis, uterus, and small intestine.
    Reduced expression in pancreatic cancer cells

        Custom PCR Arrays for NT5DC3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5DC3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NT5DC3 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nt5dc31 , 5 5'-nucleotidase domain containing 31, 5 86.69(n)1
    92.97(a)1
      10 (43.11 cM)5
    1034661  NM_175331.31  NP_780540.21 
     867790055 
    chicken
    (Gallus gallus)
    Aves NT5DC31 5'-nucleotidase domain containing 3 80.81(n)
    88.48(a)
      427914  XM_425487.4  XP_425487.4 
    lizard
    (Anolis carolinensis)
    Reptilia NT5DC36
    5'-nucleotidase domain containing 3
    82(a)
    1 ↔ 1
    5(18119318-18154208)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BX712298.12   -- 78.04(n)    BX712298.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nt5dc31 5'-nucleotidase domain containing 3 71.91(n)
    77.09(a)
      558469  XM_681686.3  XP_686778.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG18141 CG1814 53.29(n)
    48.02(a)
      35984  NM_136655.4  NP_610499.2 


    ENSEMBL Gene Tree for NT5DC3 (if available)
    TreeFam Gene Tree for NT5DC3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NT5DC3 gene
    NT5C22  NT5DC12  NT5DC22  NT5DC42  
    2 SIMAP similar genes for NT5DC3 using alignment to 3 protein entries:     NT5D3_HUMAN (see all proteins):
    NT5DC2    NT5DC1

    Find genes that share paralogs with NT5DC3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NT5DC3 (see all 1524)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs778382561,2
    F--104165648(+) TTAGAT/AGACAT 1 -- ds50012Minor allele frequency- A:0.03CSA WA 120
    rs79774591,2
    C,F,H--104165666(+) TTCCAA/G/TAAAAT 1 -- ds50016NS EA CSA WA 524
    rs1510016891,2
    --104165673(+) AAATCA/GCCCCC 1 -- ds50010--------
    rs1159353081,2
    C,F--104165736(+) ACAGGT/AACACA 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs49810331,2
    H--104165781(-) CCTCCC/TATGGA 1 -- ds50014Minor allele frequency- T:0.00NS EA 420
    rs751099751,2
    C,F--104165783(+) CATGGG/AAGGAA 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1408939141,2
    --104165790(+) GGAATC/GACAGT 1 -- ds50010--------
    rs49810321,2
    C,F,A,H--104165864(-) CAAAGG/ATTTCT 1 -- ds500111Minor allele frequency- A:0.29EA NS NA WA CSA 519
    rs42488271,2
    C,F,A--104165870(-) AAAGCC/TCAAAG 1 -- ds500110Minor allele frequency- T:0.26NA WA CSA EA 371
    rs1173658991,2
    C,F--104165976(+) AATAAC/TCTCAA 1 -- ds50011Minor allele frequency- T:0.03EA 120

    HapMap Linkage Disequilibrium report for NT5DC3 (104164231 - 104234975 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for NT5DC3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv34031CNV Loss18971310
    nsv52873CNV Loss16902084
    dgv1488n71CNV Gain21882294
    nsv899486CNV Gain21882294
    dgv1486n71CNV Gain21882294
    dgv1489n71CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NT5DC3
    DNA2.0 Custom Variant and Variant Library Synthesis for NT5DC3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611076    OMIM disorders: --


    Find genes that share disorders with NT5DC3           About GenesLikeMe

    Genetic Association Database (GAD): NT5DC3

    Export disorders for NT5DC3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NT5DC3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with NT5DC3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. (PubMed id 18839057)1, 4 Lesch K.P....Jacob C. (J Neural Transm 2008)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. TU12B1-TY, a novel gene in the region at 12q22-q23.1 frequently deleted in pancreatic cancer, shows reduced expression in pancreatic cancer cells. (PubMed id 15547748)1, 2 Yatsuoka T.... Horii A. (Oncol. Rep. 2004)
    4. A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutaneous coronary intervention. (PubMed id 21878436)1 Sampietro M.L....Jukema J.W. (Hum. Mol. Genet. 2011)
    5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    6. The common viral insertion site Evi12 is located in the 5'-noncoding region of Gnn, a novel gene with enhanced expression in two subclasses of human acute myeloid leukemia. (PubMed id 15827139)1 van den Akker E....Delwel R. (J. Virol. 2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51559 HGNC: 30826 AceView: TU12B1-TY Ensembl:ENSG00000111696 euGenes: HUgn51559
    ECgene: NT5DC3 H-InvDB: NT5DC3

    (According to HUGE)
    About This Section

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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for NT5DC3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NT5DC3 gene:
    Search GeneIP for patents involving NT5DC3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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