Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NT5DC3 Gene

protein-coding   GIFtS: 46
GCID: GC12M104164

5'-nucleotidase domain containing 3

 Explore 6 diseases affiliated with
NT5DC3 via our new
 Human Malady Compendium 
Biological research products
for NT5DC3
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
5'-Nucleotidase Domain Containing 31 2     FLJ112661
TU12B1-TY1 2 3     5'-Nucleotidase Domain-Containing Protein 32
TU12B1TY2 5     EC 3.1.3.-3
GNN3 5     GRP94-Neighboring Nucleotidase3

External Ids:    HGNC: 308261   Entrez Gene: 515592   Ensembl: ENSG000001116967   OMIM: 6110765   UniProtKB: Q86UY83   

Export aliases for NT5DC3 gene to outside databases

Previous GC identifers: GC12M102669 GC12M101226


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NT5DC3 gene promoter:
         HEN1   ISGF-3   POU2F1   POU2F1a   Arnt   RORalpha2   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNT5DC3 promoter sequence
   Search SABiosciences Chromatin IP Primers for NT5DC3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NT5DC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q22-q23.1   Ensembl cytogenetic band:  12q23.3   HGNC cytogenetic band: 12q22-q23.1

NT5DC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NT5DC3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M104164:  view genomic region     (about GC identifiers)

Start:
104,164,231 bp from pter      End:
104,234,975 bp from pter
Size:
70,745 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NT5D3_HUMAN, Q86UY8 (See protein sequence)
Recommended Name: 5'-nucleotidase domain-containing protein 3  
Size: 548 amino acids; 63420 Da
Cofactor: Binds 1 magnesium ion per subunit (By similarity)
Sequence caution: Sequence=BAA92095.1; Type=Erroneous initiation; Sequence=BAA93053.1; Type=Frameshift; Positions=62;
Secondary accessions: Q9NUM7 Q9P2T2 Q9P2T3
Alternative splicing: 2 isoforms:  Q86UY8-1   Q86UY8-2   

Explore the universe of human proteins at neXtProt for NT5DC3: NX_Q86UY8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q86UY8

  • NT5DC3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001026871.1  
    ENSEMBL proteins: 
     ENSP00000413657   ENSP00000376615   ENSP00000399171  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: NT5DC3
    OriGene Custom Protein Services for NT5DC3 
    GenScript Custom Purified and Recombinant Proteins Services for NT5DC3
    Novus Biologicals NT5DC3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NT5DC3

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0005829cytosol IEA--


    NT5DC3 for ontologies           About GeneDecksing



    NT5DC3 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NT5DC3 
    GenScript Custom Superior Antibodies Services for NT5DC3
    Novus Biologicals NT5DC3 Antibody
    Search for Antibodies for NT5DC3 at Abcam  
    Uscn Antibodies for NT5DC3
    ThermoFisher Antibody for NT5DC3

    Assay Products for NT5DC3: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NT5DC3
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for NT5DC3


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    NT5DC3 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR023214 HAD-like_dom
     IPR008380 HAD-SF_hydro_IG_5-nucl
     IPR016695 Pur_nucleotidase

    Graphical View of Domain Structure for InterPro Entry Q86UY8

    ProtoNet protein and cluster: Q86UY8

    UniProtKB/Swiss-Prot: NT5D3_HUMAN, Q86UY8
    Similarity: Belongs to the 5'(3')-deoxyribonucleotidase family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Enzyme Number (IUBMB): EC 3.1.3.-1

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: NT5DC3
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NT5DC3
    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate NT5DC3 (see all 25):
    hsa-miR-485-5p hsa-miR-1271 hsa-miR-515-5p hsa-miR-3142 hsa-miR-23a hsa-miR-3121-3p hsa-miR-330-3p hsa-miR-96
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NT5DC3 (see all 7)
    OriGene shRNA RFP: NT5DC3
    OriGene siRNA: NT5DC3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NT5DC3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NT5DC3

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NT5DC3 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NT5DC3 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: NT5DC3 (NM_001031701)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NT5DC3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NT5DC3 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NT5DC3
    Search LifeMap BioReagents cell lines for NT5DC3

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5DC3

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016787hydrolase activity IEA--
    GO:0046872metal ion binding IEA--


    NT5DC3 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NT5DC3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for NT5DC3 (Q86UY83 ENSP000003766154) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNFP013753I2D: score=1 
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NT5DC3

    1 HMDB Compound for NT5DC3    About this table
    CompoundSynonyms CAS #PubMed Ids
    MagnesiumMagnesium (see all 2)7439-95-4--
    Search CenterWatch for drugs/clinical trials and news about NT5DC3 / NT5D3 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NT5DC3 gene (2 alternative transcripts): 
    NM_016575.1  NM_001031701.2  

    Unigene Cluster for NT5DC3:

    5'-nucleotidase domain containing 3
    Hs.48428  [show with all ESTs]
    Unigene Representative Sequence: NM_001031701
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000447799 ENST00000392876(uc010swe.1) ENST00000415849 ENST00000474268
    ENST00000465502

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: NT5DC3
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NT5DC3
    8/25 QIAGEN miScript miRNA Assays for microRNAs that regulate NT5DC3 (see all 25):
    hsa-miR-485-5p hsa-miR-1271 hsa-miR-515-5p hsa-miR-3142 hsa-miR-23a hsa-miR-3121-3p hsa-miR-330-3p hsa-miR-96
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NT5DC3 (see all 7)
    OriGene shRNA RFP: NT5DC3
    OriGene siRNA: NT5DC3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NT5DC3
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NT5DC3 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NT5DC3 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: NT5DC3 (NM_001031701)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NT5DC3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NT5DC3 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NT5DC3
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NT5DC3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NT5DC3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NT5DC3

    Additional cDNA sequence: 

    AB032773.1 AK130442.1 BC052293.1 

    5 DOTS entries:

    DT.416750  DT.101963203  DT.95286617  DT.95300035  DT.121176108 

    24/138 AceView cDNA sequences (see all 138):

    BM562753 CA420627 BQ684492 BU838097 CD672505 BM855976 CA396370 AI800679 
    AJ706163 AI865829 BM795871 BF593836 AI744176 AW205506 BF476138 BQ682708 
    BC052293 AI784548 BU155544 AI041733 AL043306 NM_016575 AL524933 AA132787 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NT5DC3    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17a · 17b ^ 18 ^ 19
    SP1:        -                       -                                                           -                                             
    SP2:                                                                                                                                          
    SP3:                                -                                                                                                         
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for NT5DC3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NT5DC3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See NT5DC3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NT5DC3

    SOURCE GeneReport for Unigene cluster: Hs.48428

    UniProtKB/Swiss-Prot: NT5D3_HUMAN, Q86UY8
    Tissue specificity: Expressed in brain, placenta, skeletal muscle, pancreas, testis, uterus, and small intestine.
    Reduced expression in pancreatic cancer cells

        SABiosciences Custom PCR Arrays for NT5DC3
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NT5DC3
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NT5DC3
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NT5DC3
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NT5DC3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5DC3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NT5DC3 gene from 7/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves NT5DC31 5'-nucleotidase domain containing 3 82.52(n)
    91.26(a)
      427914  XM_425487.3  XP_425487.3 
    lizard
    (Anolis carolinensis)
    Reptilia NT5DC36
    --
    88(a)
    1 ↔ 1
    5(18126455-18141417)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BX712298.12   -- 78.04(n)    BX712298.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nt5dc31 5'-nucleotidase domain containing 3 71.91(n)
    77.09(a)
      558469  XM_681686.2  XP_686778.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG18141 CG1814 53.36(n)
    48.02(a)
      35984  NM_136655.3  NP_610499.2 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G238906
    AT5G489606
    HAD-superfamily hydrolase, subfamily IG, 5'-nucleo...
    HAD-superfamily hydrolase, subfamily IG, 5'-nucleo...
    30(a)
    20(a)
    1 ↔ many
    possible ortholog
    2(10170601-10173927)
    5(19849543-19853564)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    5-nucleotidase domain-containing protein, putative...
    5-nucleotidase domain-containing protein, putative...
    32(a)
    19(a)
    1 ↔ many
    possible ortholog
    9(15399687-15405413)
    1(8274474-8282966)


    ENSEMBL Gene Tree for NT5DC3 (if available)
    TreeFam Gene Tree for NT5DC3 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NT5DC3 gene
    NT5DC12  NT5C22  NT5DC22  NT5DC42  
    2 SIMAP similar genes for NT5DC3 using alignment to 3 protein entries:     NT5D3_HUMAN (see all proteins):
    NT5DC2    NT5DC1

    NT5DC3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1359 NCBI SNPs in NT5DC3 are shown (see all 1359    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs778382561,2
    --104165648(+) TTAGAT/AGACAT 1 -- ds50012Minor allele frequency- A:0.03CSA WA 120
    rs79774591,2
    C,F,H,--104165666(+) TTCCAG/TAAAAT 1 -- ds50016Minor allele frequency- T:0.02NS EA CSA WA 524
    rs1510016891,2
    --104165673(+) AAATCA/GCCCCC 1 -- ds50010--------
    rs1159353081,2
    F,--104165736(+) ACAGGT/AACACA 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs49810331,2
    H--104165781(-) CCTCCC/TATGGA 1 -- ds50014Minor allele frequency- T:0.00NS EA 420
    rs751099751,2
    C,F,--104165783(+) CATGGG/AAGGAA 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1408939141,2
    --104165790(+) GGAATC/GACAGT 1 -- ds50010--------
    rs49810321,2
    C,F,A,H,--104165864(-) CAAAGG/ATTTCT 1 -- ds500111Minor allele frequency- A:0.29EA NS NA WA CSA 519
    rs42488271,2
    C,F,A,--104165870(-) AAAGCC/TCAAAG 1 -- ds500110Minor allele frequency- T:0.26NA WA CSA EA 371
    rs1173658991,2
    F,--104165976(+) AATAAC/TCTCAA 1 -- ds50011Minor allele frequency- T:0.03EA 120

    HapMap Linkage Disequilibrium report for NT5DC3 (104164231 - 104234975 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 5 variations for NT5DC3
         5 CNVs: 76142 47868 86550 5688 86549

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NT5DC3
    DNA2.0 Custom Variant and Variant Library Synthesis for NT5DC3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NT5DC3 for disorders           About GeneDecksing

    OMIM gene information: 611076    OMIM disorders: --

    6 diseases for NT5DC3:    About MalaCards
    acute myeloid leukemia    myeloid leukemia    adhd    pancreatic cancer
    leukemia    pancreatitis


    Export disorders for NT5DC3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NT5DC3 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with NT5DC3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. TU12B1-TY, a novel gene in the region at 12q22-q23.1 frequently deleted in pancreatic cancer, shows reduced expression in pancreatic cancer cells. (PubMed id 15547748)1, 2 Yatsuoka T....Horii A. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. A genome-wide association study identifies a region at chromosome 12 as a potential susceptibility locus for restenosis after percutan eous coronary intervention. (PubMed id 21878436)1 Sampietro M.L....Jukema J.W. (2011)
    4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    5. Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies. (PubMed id 18839057)1 Lesch K.P....Jacob C. (2008)
    6. The common viral insertion site Evi12 is located in the 5'-noncoding region of Gnn, a novel gene with enhanced expression in two subclasses of human acute myeloid leukemia. (PubMed id 15827139)1 van den Akker E....Delwel R. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51559 HGNC: 30826 AceView: TU12B1-TY Ensembl:ENSG00000111696 euGenes: HUgn51559
    ECgene: NT5DC3 H-InvDB: NT5DC3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NT5DC3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NT5DC3 gene:
    Search GeneIP for patents involving NT5DC3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for NT5DC3  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NT5DC3   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NT5DC3  
     OriGene Protein Over-expression Lysate for NT5DC3   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for NT5DC3   OriGene 3'-UTR Clone for NT5DC3  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NT5DC3   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NT5DC3  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NT5DC3   OriGene Custom Protein Services for NT5DC3  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NT5DC3
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NT5DC3
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NT5DC3
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NT5DC3
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NT5DC3
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NT5DC3
     GenScript Custom Purified and Recombinant Proteins Services for NT5DC3 GenScript cDNA clones with any tag delivered in your preferred vector for NT5DC3
     GenScript Custom Assay Services for NT5DC3 GenScript Custom Superior Antibodies Services for NT5DC3
     GenScript Custom overexpressing Cell Line Services for NT5DC3 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in NT5DC3 promoter
     Search Chromatin IP Primers for NT5DC3
     RT2 qPCR Primer Assay in human, mouse, rat NT5DC3
     Search GNC Networks for NT5DC3
     SABiosciences Custom PCR Arrays for NT5DC3
     Search Tocris compounds for NT5DC3
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     NT5DC3 antibodies
     NT5DC3 lysates
     Search for Antibodies for NT5DC3 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for NT5DC3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     NT5DC3 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for NT5DC3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5DC3
     Browse SwitchGear 3'UTR luciferase reporter plasmids for NT5DC3
     SwitchGear Promoter luciferase reporter plasmids for NT5DC3
     ThermoFisher Antibody for NT5DC3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NT5DC3
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NT5DC3 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4