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NT5DC2 Gene

protein-coding   GIFtS: 49
GCID: GC03M052534

5'-Nucleotidase Domain Containing 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
5'-Nucleotidase Domain Containing 21 2
5'-Nucleotidase Domain-Containing Protein 22
EC 3.1.3.-3

External Ids:    HGNC: 257171   Entrez Gene: 649432   Ensembl: ENSG000001682687   UniProtKB: Q9H8573   

Export aliases for NT5DC2 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NT5DC2 Gene:
NT5DC2 (5'-nucleotidase domain containing 2) is a protein-coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is NT5DC3.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_022517.19  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NT5DC2 gene promoter:
         E2F-3a   E2F-4   E2F-5   E2F   E2F-2   GATA-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNT5DC2 promoter sequence
   Search Chromatin IP Primers for NT5DC2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NT5DC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.1   Ensembl cytogenetic band:  3p21.1   HGNC cytogenetic band: 3p21.1

NT5DC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NT5DC2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M052534:  view genomic region     (about GC identifiers)

Start:
52,558,385 bp from pter      End:
52,569,093 bp from pter
Size:
10,709 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NT5D2_HUMAN, Q9H857 (See protein sequence)
Recommended Name: 5'-nucleotidase domain-containing protein 2  
Size: 520 amino acids; 60719 Da
Sequence caution: Sequence=AAH14550.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB14064.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: C9JTZ6 E9PAL9 O95888 Q96C80 Q9H9Z8
Alternative splicing: 4 isoforms:  Q9H857-1   Q9H857-2   Q9H857-3   Q9H857-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NT5DC2: NX_Q9H857

Explore proteomics data for NT5DC2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys102
  • Modification sites at PhosphoSitePlus

  • See NT5DC2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001127703.1  NP_075059.1  

    ENSEMBL proteins: 
     ENSP00000418780   ENSP00000302468   ENSP00000406933   ENSP00000419547   ENSP00000419774  
     ENSP00000417269   ENSP00000418583   ENSP00000306017  

    NT5DC2 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for NT5DC2
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for NT5DC2 

     
    antibodies-online proteins for NT5DC2 (3 products) 

     
    antibodies-online peptides for NT5DC2

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    Search for Antibodies for NT5DC2 at Abcam
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    antibodies-online antibodies for NT5DC2 (11 products) 

    NT5DC2 Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for NT5DC2 
    antibodies-online kits for NT5DC2 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR023214 HAD-like_dom
     IPR008380 HAD-SF_hydro_IG_5-nucl
     IPR016695 Pur_nucleotidase

    Graphical View of Domain Structure for InterPro Entry Q9H857

    ProtoNet protein and cluster: Q9H857

    1 Blocks protein domain: IPB001064 Beta and gamma crystallin

    UniProtKB/Swiss-Prot: NT5D2_HUMAN, Q9H857
    Similarity: Belongs to the 5'(3')-deoxyribonucleotidase family


    Find genes that share domains with NT5DC2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Number (IUBMB): EC 3.1.3.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016787hydrolase activity IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with NT5DC2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for NT5DC2:
     Decreased viability of wild-ty 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NT5DC2

    miRNA
    Products:
        
    miRTarBase miRNAs that target NT5DC2:
    hsa-let-7e-5p (MIRT051686), hsa-let-7b-5p (MIRT052241), hsa-mir-455-3p (MIRT037848), hsa-mir-484 (MIRT042173), hsa-mir-760 (MIRT036776), hsa-mir-423-3p (MIRT042644), hsa-mir-16-5p (MIRT051291), hsa-mir-26b-5p (MIRT030270), hsa-mir-221-3p (MIRT046905)

    Block miRNA regulation of human, mouse, rat NT5DC2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate NT5DC2:
    hsa-miR-137
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for NT5DC2
    Predesigned siRNA for gene silencing in human, mouse, rat NT5DC2

    Gene Editing
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    OriGene clones in human, mouse for NT5DC2 (see all 13)
    OriGene ORF clones in mouse, rat for NT5DC2
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    GenScript: all cDNA clones in your preferred vector (see all 2): NT5DC2 (NM_001134231)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NT5DC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NT5DC2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for NT5DC2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5DC2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion2
    cytosol1
    nucleus1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NT5DC2
    Interactions:

        Search GeneGlobe Interaction Network for NT5DC2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for NT5DC2 (Q9H8572, 3 ENSP000004069334) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRAF1Q130772, 3, ENSP000003629944MINT-49517 I2D: score=2 STRING: ENSP00000362994
    TRAF2Q129332, 3, ENSP000002476684MINT-49551 I2D: score=2 STRING: ENSP00000247668
    TRMT10CQ7L0Y33, ENSP000003123564I2D: score=1 STRING: ENSP00000312356
    TSG101Q998163, ENSP000002519684I2D: score=1 STRING: ENSP00000251968
    TOLLIPQ9H0E23, ENSP000003147334I2D: score=1 STRING: ENSP00000314733
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NT5DC2 (NT5D2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NT5DC2 gene (2 alternative transcripts): 
    NM_001134231.1  NM_022908.2  

    Unigene Cluster for NT5DC2:

    5'-nucleotidase domain containing 2
    Hs.84753  [show with all ESTs]
    Unigene Representative Sequence: AK091962
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000463947 ENST00000479024 ENST00000307076(uc003deo.3) ENST00000422318(uc003den.3)
    ENST00000462261 ENST00000459839 ENST00000492555(uc010hmj.3) ENST00000469616
    ENST00000466112 ENST00000478091 ENST00000489316 ENST00000486792 ENST00000471522
    ENST00000487779 ENST00000490681 ENST00000307092(uc003dem.3 uc010hmi.3)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NT5DC2 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate NT5DC2:
    hsa-miR-137
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NT5DC2
    Predesigned siRNA for gene silencing in human, mouse, rat NT5DC2
    Clone
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    OriGene clones in human, mouse for NT5DC2 (see all 13)
    OriGene ORF clones in mouse, rat for NT5DC2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): NT5DC2 (NM_001134231)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NT5DC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NT5DC2
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for NT5DC2
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat NT5DC2
      QuantiTect SYBR Green Assays in human, mouse, rat NT5DC2
      QuantiFast Probe-based Assays in human, mouse, rat NT5DC2

    Additional mRNA sequence: 

    AF131781.1 AK022504.1 AK023995.1 AK091962.1 AK092469.1 BC014550.1 BC047747.1 

    Selected DOTS entries (see all 26):

    DT.100821306  DT.100821315  DT.97824967  DT.95080636  DT.100821311  DT.118715  DT.95250396  DT.75154693 
    DT.100030652  DT.100030656  DT.120869757  DT.100821314  DT.120869854  DT.120869933  DT.40117496  DT.100821312 
    DT.92029584  DT.92453166  DT.92453168  DT.95080633  DT.99981211  DT.100821313  DT.70103841  DT.91842775 

    Selected AceView cDNA sequences (see all 293):

    BQ711598 AI363467 BU856379 BQ004870 BM823824 F12537 CB135813 BQ024466 
    BM709509 AI910442 BG910527 BQ017593 AK092469 BM699980 CA430455 BU742947 
    BE315077 BM755717 BE018250 R63586 CR612874 AX747560 Z41597 BQ064579 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NT5DC2 (see all 15)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b ^ 13a · 13b · 13c ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^
    SP1:                                                                                                              -                                             
    SP2:                                                                    -                                         -                                             
    SP3:                                                                                                              -                                             
    SP4:                    -     -                                                                                                                                 
    SP5:                                                                    -                                                                                       

    ExUns: 19a · 19b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for NT5DC2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NT5DC2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCCACATCC
    NT5DC2 Expression
    About this image


    NT5DC2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Pancreas (Endocrine System)    fully expand to see all 2 entries
             Bipotent Endocrine/Duct Progenitor Cells Dorsal Pancreatic Bud
     
     Liver (Hepatobiliary System)
             Mesothelial Cells Hepatic Mesenchyme
     
     Skeletal Muscle (Muscoskeletal System)
             Extraocular Muscles
     
     Ovary (Reproductive System)
     
     Adrenal Gland (Endocrine System)
    NT5DC2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NT5DC2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.84753
        Custom PCR Arrays for NT5DC2
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5DC2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NT5DC2 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nt5dc21 , 5 5'-nucleotidase domain containing 21, 5 90.09(n)1
    97.95(a)1
      14 (19.09 cM)5
    700211  NM_027289.11  NP_081565.11 
     311348535 
    chicken
    (Gallus gallus)
    Aves NT5DC21 5'-nucleotidase domain containing 2 74.74(n)
    79.11(a)
      415895  XM_414247.4  XP_414247.3 
    lizard
    (Anolis carolinensis)
    Reptilia NT5DC26
    5'-nucleotidase domain containing 2
    73(a)
    1 ↔ 1
    2(154746934-154783236)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC538402 hypothetical protein MGC53840 78.05(n)    BC046742.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb83e032 Transcribed sequence with weak similarity to protein more 78.51(n)    BI885890.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG18146
    --
    40(a)
    1 → many
    2R(5464932-5469352)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G238901 AT2G23890 47.59(n)
    40.42(a)
      816921  NM_127950.3  NP_179967.3 
    rice
    (Oryza sativa)
    Liliopsida Os09g04246001 Os09g0424600 48.4(n)
    40.28(a)
      4347105  NM_001069753.1  NP_001063218.1 


    ENSEMBL Gene Tree for NT5DC2 (if available)
    TreeFam Gene Tree for NT5DC2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NT5DC2 gene
    NT5DC32  NT5C22  NT5DC12  NT5DC42  
    1 SIMAP similar gene for NT5DC2 using alignment to 5 protein entries:     NT5D2_HUMAN (see all proteins):
    NT5DC3

    Find genes that share paralogs with NT5DC2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for NT5DC2
    PGOHUM00000241101


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NT5DC2 (see all 266)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1445632571,2
    C,F--52559025(+) TCAGCG/AAGTGC 4 /S /L mis11Minor allele frequency- A:0.00NA 3648
    rs1437994711,2
    C,F--52559042(+) TGCTCC/TGTGTT 4 T syn12Minor allele frequency- T:0.00NA EU 4019
    rs2019630221,2
    --52559084(+) ATGATA/GGCGCC 4 A syn10--------
    rs2015494061,2
    C--52559085(+) TGATGA/GCGCCT 4 A V mis10--------
    rs2013277871,2
    C--52559251(+) GTCCCC/TGAAGT 4 R G mis10--------
    rs2007733481,2
    --52559266(+) CACGCA/GGGGGC 4 R C mis10--------
    rs1996506251,2
    --52559282(+) CATTCC/TGTCAA 4 T syn10--------
    rs1817838461,2
    --52559404(+) CCAGCC/TGGATG 2 -- int10--------
    rs1484779251,2
    --52559490(+) AAGGGA/GATTCT 2 -- int10--------
    rs117092841,2
    C,F,A,H--52559705(+) TCACCA/GGGGCC 2 -- int117Minor allele frequency- G:0.43NA EA WA CSA 740

    HapMap Linkage Disequilibrium report for NT5DC2 (52558385 - 52569093 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for NT5DC2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv3820CNV Insertion18451855
    dgv5137n71CNV Loss21882294
    nsv834697CNV Loss17160897
    nsv876789CNV Loss21882294
    dgv5138n71CNV Loss21882294
    esv27812CNV Loss19812545

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NT5DC2 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with NT5DC2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 3 Yu W.... Gibbs R.A. (Genome Res. 1997)
    4. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (Anal. Biochem. 1996)
    5. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PubMed id 23974872)1 Ripke S....Sullivan P.F. (Nat. Genet. 2013)
    6. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S.... Dorf M.E. (Immunity 2011)
    7. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PubMed id 21926972)1 (Nat. Genet. 2011)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64943 HGNC: 25717 AceView: FLJ12442 Ensembl:ENSG00000168268 euGenes: HUgn64943
    ECgene: NT5DC2 H-InvDB: NT5DC2

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NT5DC2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NT5DC2 gene:
    Search GeneIP for patents involving NT5DC2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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