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NT5DC1 Gene

protein-coding   GIFtS: 48
GCID: GC06P116421

5'-Nucleotidase Domain Containing 1

(Previous names: 5'-nucleotidase, cytosolic II-like 1)
(Previous symbol: NT5C2L1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
5'-Nucleotidase Domain Containing 11 2     5'-Nucleotidase, Cytosolic II-Like 1 Protein2
NT5C2L11 2 3     C6orf2002
5'-Nucleotidase, Cytosolic II-Like 11     LP26422
5'-Nucleotidase Domain-Containing Protein 12     EC 3.1.3.-3

External Ids:    HGNC: 215561   Entrez Gene: 2212942   Ensembl: ENSG000001784257   UniProtKB: Q5TFE43   

Export aliases for NT5DC1 gene to outside databases

Previous GC identifers: GC06P116529 GC06P114002


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NT5DC1 Gene:
While the exact function of the protein encoded by this gene is not known, it belongs to the
5'(3')-deoxyribonucleotidase family. (provided by RefSeq, May 2010)

GeneCards Summary for NT5DC1 Gene:
NT5DC1 (5'-nucleotidase domain containing 1) is a protein-coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is NT5DC3.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NT5DC1 gene promoter:
         Max1   AP-1   AML1a   Meis-1b   C/EBPalpha   Evi-1   Meis-1a   MRF-2   c-Myc   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNT5DC1 promoter sequence
   Search Chromatin IP Primers for NT5DC1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NT5DC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q22.1   Ensembl cytogenetic band:  6q22.1   HGNC cytogenetic band: 6q22.31

NT5DC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NT5DC1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P116421:  view genomic region     (about GC identifiers)

Start:
116,421,999 bp from pter      End:
116,570,660 bp from pter
Size:
148,662 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NT5D1_HUMAN, Q5TFE4 (See protein sequence)
Recommended Name: 5'-nucleotidase domain-containing protein 1  
Size: 455 amino acids; 51845 Da
Sequence caution: Sequence=AAP34458.1; Type=Frameshift; Positions=339;
Secondary accessions: B2RND9 Q6XYD5

Explore the universe of human proteins at neXtProt for NT5DC1: NX_Q5TFE4

Explore proteomics data for NT5DC1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys154
  • Modification sites at PhosphoSitePlus

  • See NT5DC1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_689942.2  
    ENSEMBL proteins: 
     ENSP00000326858   ENSP00000393578   ENSP00000404419   ENSP00000433238  

    NT5DC1 Human Recombinant Protein Products:

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    Novus Biologicals NT5DC1 Protein
    Novus Biologicals NT5DC1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for NT5DC1 

     
    antibodies-online proteins for NT5DC1 (3 products) 

     
    antibodies-online peptides for NT5DC1

    NT5DC1 Antibody Products:

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    Abcam antibodies for NT5DC1
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for NT5DC1
    antibodies-online antibodies for NT5DC1 (20 products) 

    NT5DC1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for NT5DC1 
    antibodies-online kits for NT5DC1 (3 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR023214 HAD-like_dom
     IPR008380 HAD-SF_hydro_IG_5-nucl

    Graphical View of Domain Structure for InterPro Entry Q5TFE4

    ProtoNet protein and cluster: Q5TFE4

    UniProtKB/Swiss-Prot: NT5D1_HUMAN, Q5TFE4
    Similarity: Belongs to the 5'(3')-deoxyribonucleotidase family


    Find genes that share domains with NT5DC1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Number (IUBMB): EC 3.1.3.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016787hydrolase activity IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with NT5DC1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for NT5DC1:
     Decreased POU5F1-GFP protein e 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NT5DC1

    miRNA
    Products:
        
    miRTarBase miRNAs that target NT5DC1:
    hsa-mir-10a-5p (MIRT047616), hsa-mir-16-5p (MIRT004370), hsa-mir-15a-5p (MIRT003876)

    Block miRNA regulation of human, mouse, rat NT5DC1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NT5DC1 (see all 11):
    hsa-miR-4324 hsa-miR-100* hsa-miR-125a-5p hsa-miR-576-5p hsa-miR-3647-3p hsa-miR-125b hsa-miR-3143 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidNT5DC1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NT5DC1
    Predesigned siRNA for gene silencing in human, mouse, rat NT5DC1

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for NT5DC1

    Clone
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    OriGene clones in human, mouse for NT5DC1 (see all 7)
    OriGene ORF clones in mouse, rat for NT5DC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NT5DC1 (NM_152729)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NT5DC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NT5DC1

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for NT5DC1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5DC1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NT5DC1
    Interactions:

        Search GeneGlobe Interaction Network for NT5DC1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for NT5DC1 (Q5TFE43 ENSP000003268584) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DDA1Q9BW613I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    ECHDC1ENSP000003572784STRING: ENSP00000357278
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NT5DC1 (NT5D1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NT5DC1 gene: 
    NM_152729.2  

    Unigene Cluster for NT5DC1:

    5'-nucleotidase domain containing 1
    Hs.520341  [show with all ESTs]
    Unigene Representative Sequence: NM_152729
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000319550(uc003pwj.3 uc003pwl.3) ENST00000419791 ENST00000417846
    ENST00000460749
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NT5DC1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NT5DC1 (see all 11):
    hsa-miR-4324 hsa-miR-100* hsa-miR-125a-5p hsa-miR-576-5p hsa-miR-3647-3p hsa-miR-125b hsa-miR-3143 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidNT5DC1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NT5DC1
    Predesigned siRNA for gene silencing in human, mouse, rat NT5DC1
    Clone
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    OriGene clones in human, mouse for NT5DC1 (see all 7)
    OriGene ORF clones in mouse, rat for NT5DC1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NT5DC1 (NM_152729)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NT5DC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NT5DC1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NT5DC1
    OriGene qSTAR qPCR primer pairs in human, mouse for NT5DC1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NT5DC1
      QuantiTect SYBR Green Assays in human, mouse, rat NT5DC1
      QuantiFast Probe-based Assays in human, mouse, rat NT5DC1

    Additional mRNA sequence: 

    AF245044.1 AK090918.1 AK290408.1 AK308337.1 AY203935.1 BC015138.1 BC056664.1 BC063504.1 
    BC108699.1 BC136832.1 BC136841.1 

    11 DOTS entries:

    DT.91738067  DT.75140782  DT.121389710  DT.100743827  DT.100842548  DT.121389750  DT.95173000  DT.442992 
    DT.99977644  DT.95218743  DT.121389882 

    Selected AceView cDNA sequences (see all 197):

    CR624824 BQ448230 AA761487 BG319443 BQ774140 AI520684 BX369720 BM830026 
    AK090918 BM676990 BM991703 BU686554 AA370093 AA503740 AA702170 AA765076 
    AW513009 AA053120 AA811820 CA390074 H96287 AX746681 N20500 AW198077 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NT5DC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATGCTTTAA
    NT5DC1 Expression
    About this image

    NT5DC1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NT5DC1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.520341
        Custom PCR Arrays for NT5DC1
    Primer
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    OriGene qPCR primer pairs and template standards for NT5DC1
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    QuantiFast Probe-based Assays in human, mouse, rat NT5DC1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5DC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NT5DC1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nt5dc11 , 5 5'-nucleotidase domain containing 11, 5 83.11(n)1
    80.8(a)1
      10 (18.85 cM)5
    3196381  NM_176968.41  NP_795942.21 
     342882885 
    chicken
    (Gallus gallus)
    Aves NT5DC11 5'-nucleotidase domain containing 1 74.01(n)
    75.55(a)
      421746  XM_003641006.2  XP_003641054.1 
    lizard
    (Anolis carolinensis)
    Reptilia NT5DC16
    5'-nucleotidase domain containing 1
    72(a)
    1 ↔ 1
    1(186299189-186448832)
    zebrafish
    (Danio rerio)
    Actinopterygii nt5dc11 5'-nucleotidase domain containing 1 61.63(n)
    63.11(a)
      568757  NM_001104943.1  NP_001098413.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG22771 CG2277 47.07(n)
    38.06(a)
      38148  NM_001274319.1  NP_001261248.1 


    ENSEMBL Gene Tree for NT5DC1 (if available)
    TreeFam Gene Tree for NT5DC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NT5DC1 gene
    NT5DC32  NT5C22  NT5DC22  NT5DC42  
    1 SIMAP similar gene for NT5DC1 using alignment to 6 protein entries:     NT5D1_HUMAN (see all proteins):
    NT5DC3

    Find genes that share paralogs with NT5DC1           About GenesLikeMe


    4 Pseudogenes.org Pseudogenes for NT5DC1
    PGOHUM00000235479 PGOHUM00000243406 PGOHUM00000241449 PGOHUM00000242022


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NT5DC1 (see all 2919)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1422741511,2
    C--114007704(+) AAGTT-/CTTTTT 1 -- int10--------
    rs1445541891,2
    C--114015888(+) TTGGG-/GGGA  
            
    GGGGG
    1 -- int10--------
    rs121990051,2
    C--114015891(+) GGGGGA/GGGGGG 1 -- int1 trp30--------
    rs1407221,2
    C--114021427(+) CTGTG-/GG    
       G
    /GGT
    TGTAC
    2 -- cds13NA CSA 8
    rs77498871,2
    C--114037232(+) atataC/Tacaca 1 -- int11Minor allele frequency- T:0.50WA 2
    rs3682537211,2
    C--114037233(-) tgtgt-/GTatata 1 -- int10--------
    rs1474320431,2
    C--114054703(+) AAAAG-/TTTTTCA 1 -- int10--------
    rs105268291,2
    C--114054706(+) AGTTTTT/-CACAA 1 -- int11Minor allele frequency- -:0.50NA 2
    rs1999483021,2
    C--114069451(+) GGTGTC/TTTTTT 1 -- int10--------
    rs1485094811,2
    C--114083585(+) GGAGA-/GTGTGTG 1 -- int10--------

    HapMap Linkage Disequilibrium report for NT5DC1 (116421999 - 116570660 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for NT5DC1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv523972CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NT5DC1
    DNA2.0 Custom Variant and Variant Library Synthesis for NT5DC1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with NT5DC1           About GenesLikeMe

    Genetic Association Database (GAD): NT5DC1
    Human Genome Epidemiology (HuGE) Navigator: NT5DC1 (5 documents)

    Export disorders for NT5DC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NT5DC1 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with NT5DC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    2. Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. (PubMed id 18978678)1, 4 Vieira A.R....Marazita M.L. (Genet. Med. 2008)
    3. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    6. Seven new loci associated with age-related macular degeneration. (PubMed id 23455636)1 Fritsche L.G....Abecasis G.R. (Nat. Genet. 2013)
    7. GWAS of dental caries patterns in the permanent dentition. (PubMed id 23064961)1 Shaffer J.R....Marazita M.L. (J. Dent. Res. 2013)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 221294 HGNC: 21556 AceView: NT5C2L1 Ensembl:ENSG00000178425 euGenes: HUgn221294
    ECgene: NT5DC1 H-InvDB: NT5DC1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NT5DC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NT5DC1 gene:
    Search GeneIP for patents involving NT5DC1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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