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NT5C3B Gene

protein-coding   GIFtS: 43
GCID: GC17M039982

5'-Nucleotidase, Cytosolic IIIB

(Previous names: 5'-nucleotidase, cytosolic III-like)
(Previous symbol: NT5C3L)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
5'-Nucleotidase, Cytosolic IIIB1 2     CN-III-Like Protein2 3
NT5C3L1 2 3     N(7)-Methylguanylate 5'-Phosphatase2 3
5'-Nucleotidase, Cytosolic III-Like1 2     7-Methylguanosine Phosphate-Specific 5'-Nucleotidase2
Cytosolic 5'-Nucleotidase 3B2 3     EC 3.1.3.53
Cytosolic 5'-Nucleotidase III-Like Protein2 3     EC 3.1.3.913
7-Methylguanosine Nucleotidase2 3     

External Ids:    HGNC: 283001   Entrez Gene: 1150242   Ensembl: ENSG000001416987   UniProtKB: Q969T73   

Export aliases for NT5C3B gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NT5C3B Gene:
NT5C3B (5'-nucleotidase, cytosolic IIIB) is a protein-coding gene. Diseases associated with NT5C3B include lynch syndrome, and malaria. GO annotations related to this gene include 5'-nucleotidase activity and nucleotide binding. An important paralog of this gene is NT5C3A.

UniProtKB/Swiss-Prot: 5NT3B_HUMAN, Q969T7
Function: Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic
phosphate. The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its
incorporation into nucleic acids. Also has weak activity for CMP. UMP and purine nucleotides are poor substrates




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for NT5C3B
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNT5C3B promoter sequence
   Search Chromatin IP Primers for NT5C3B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NT5C3B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.2   Ensembl cytogenetic band:  17q21.2   HGNC cytogenetic band: 17q21.2

NT5C3B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NT5C3B gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M039982:  view genomic region     (about GC identifiers)

Start:
39,981,334 bp from pter      End:
39,992,523 bp from pter
Size:
11,190 bases      Orientation:
minus strand

1 alternative location:
Chr17-,NW_003571052 111,724-122,913     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: 5NT3B_HUMAN, Q969T7 (See protein sequence)
Recommended Name: 7-methylguanosine phosphate-specific 5'-nucleotidase  
Size: 300 amino acids; 34389 Da
Subunit: Monomer
Secondary accessions: A8MWB9 C9JKC4 Q7L3B7
Alternative splicing: 2 isoforms:  Q969T7-1   Q969T7-2   

Explore the universe of human proteins at neXtProt for NT5C3B: NX_Q969T7

Explore proteomics data for NT5C3B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NT5C3B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_443167.4  
    ENSEMBL proteins: 
     ENSP00000429878   ENSP00000389948   ENSP00000397742   ENSP00000392092   ENSP00000475710  
     ENSP00000431066   ENSP00000269534  

    NT5C3B Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR006434 Pyrimidine_nucleotidase_eu
     IPR023214 HAD-like_dom

    Graphical View of Domain Structure for InterPro Entry Q969T7

    ProtoNet protein and cluster: Q969T7

    UniProtKB/Swiss-Prot: 5NT3B_HUMAN, Q969T7
    Similarity: Belongs to the pyrimidine 5'-nucleotidase family


    NT5C3B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: 5NT3B_HUMAN, Q969T7
    Function: Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic
    phosphate. The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its
    incorporation into nucleic acids. Also has weak activity for CMP. UMP and purine nucleotides are poor substrates
    Catalytic activity: N(7)-methyl-GMP + H(2)O = N(7)-methyl-guanosine + phosphate
    Catalytic activity: CMP + H(2)O = cytidine + phosphate
    Catalytic activity: A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate
    Biophysicochemical properties: Kinetic parameters: KM=7.8 uM for m(7)GMP; KM=79 uM for CMP; KM=355 uM for GMP;
    KM=456 uM for AMP; KM=439 uM for UMP; Vmax=0.41 umol/min/mg enzyme with m(7)GMP as substrate; Vmax=12 umol/min/mg
    enzyme with CMP as substrate; Vmax=0.13 umol/min/mg enzyme with GMP as substrate; Vmax=0.07 umol/min/mg enzyme
    with AMP as substrate; Vmax=10.7 umol/min/mg enzyme with UMP as substrate; Note=kcat is 0.24 sec(-1) with
    m(7)GMP. kcat is 7 sec(-1) with CMP. kcat is 0.07 sec(-1) with GMP. kcat is 0.04 sec(-1) with AMP. kcat is 6.2
    sec(-1) with UMP;

         Enzyme Numbers (IUBMB): EC 3.1.3.911 EC 3.1.3.51

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0000287magnesium ion binding IEA--
    GO:0005515protein binding IPI--
    GO:00082535'-nucleotidase activity IEA--
         
    NT5C3B for ontologies           About GeneDecksing


    Animal Models:
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    miRNA
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    miRTarBase miRNAs that target NT5C3B:
    hsa-mir-193b-3p (MIRT041574)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    5NT3B_HUMAN, Q969T7: Cytoplasm (Potential)

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    NT5C3B for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NT5C3B About    
    See pathways by source

    SuperPathContained pathways About
    1Purine metabolism (KEGG)
    Purine metabolism0.38
    Pyrimidine metabolism0.38
    2Nicotinate and nicotinamide metabolism
    Nicotinate and nicotinamide metabolism0.43
    3Metabolism
    Metabolic pathways0.38

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    4 Kegg Pathways  (Kegg details for NT5C3B):
        Purine metabolism
    Pyrimidine metabolism
    Nicotinate and nicotinamide metabolism
    Metabolic pathways


    NT5C3B for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NT5C3B
    Interactions:

        Search GeneGlobe Interaction Network for NT5C3B

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for NT5C3B (Q969T71, 3 ENSP000002695344) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MLH1P406921, 3EBI-2932564,EBI-744248 I2D: score=1 
    IMPDH2ENSP000003215844STRING: ENSP00000321584
    IMPDH1ENSP000003450964STRING: ENSP00000345096
    NMRK1ENSP000003543874STRING: ENSP00000354387
    NMRK2ENSP000001689774STRING: ENSP00000168977
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009117nucleotide metabolic process IEA--

    NT5C3B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NT5C3B (5NT3B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NT5C3B gene: 
    NM_052935.4  

    Unigene Cluster for NT5C3B:

    5'-nucleotidase, cytosolic IIIB
    Hs.237536  [show with all ESTs]
    Unigene Representative Sequence: NR_033465
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000517701 ENST00000469698 ENST00000523903(uc021txn.1 uc002hxy.4)
    ENST00000521789 ENST00000470690 ENST00000393910 ENST00000435506 ENST00000415460
    ENST00000476921 ENST00000445655 ENST00000486304 ENST00000460893 ENST00000481693
    ENST00000475053 ENST00000495317 ENST00000520442 ENST00000269534(uc021txo.1)

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidNT5C3B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat NT5C3B
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      QuantiTect SYBR Green Assays in human, mouse, rat NT5C3B
      QuantiFast Probe-based Assays in human, mouse, rat NT5C3B

    Additional mRNA sequence: 

    BC013742.1 BC014132.2 BC016971.1 BC067788.1 NR_033464.1 NR_033465.1 

    19 DOTS entries:

    DT.116774  DT.100029871  DT.100819638  DT.100694315  DT.100721631  DT.100819649  DT.100819636  DT.91754286 
    DT.95260712  DT.95260729  DT.120946470  DT.95260719  DT.95260732  DT.95353845  DT.100819640  DT.120946443 
    DT.91754280  DT.95260720  DT.91950662 

    Selected AceView cDNA sequences (see all 329):

    CR615474 BQ638195 AI334213 AI871820 BM712068 AI093597 CR618474 CR595234 
    CR613714 AA608946 BE385358 AI468961 AI083772 CR617027 CR608329 CN480784 
    CD743234 AA643982 CR624506 AW411064 BQ446733 BM998235 AW161691 AI358365 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NT5C3B (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b
    SP1:                                            -     -     -                 -     -                             -                     
    SP2:                                            -     -     -                 -     -                             -                     
    SP3:                                                                          -     -                             -                     
    SP4:                                -           -     -     -                 -     -           -                 -                     
    SP5:                                -           -     -     -                 -     -                                                   


    ECgene alternative splicing isoforms for NT5C3B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NT5C3B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    NT5C3B Expression
    About this image


    NT5C3B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Muscle Progenitor Cells Mandibular Arch Muscles
     
     Eye (Sensory Organs)
             Retina
     
     Thyroid (Endocrine System)
     
     Testis (Reproductive System)
    NT5C3B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NT5C3B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.237536
        Custom PCR Arrays for NT5C3B
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5C3B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NT5C3B gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nt5c3b1 , 5 5'-nucleotidase, cytosolic III-like5
    5'-nucleotidase, cytosolic IIIB1
    87.29(n)1
    89.97(a)1
      11 (63.47 cM)5
    681061  NM_001102650.11  NP_001096120.11 
     1004223215 
    chicken
    (Gallus gallus)
    Aves NT5C3L1 5'-nucleotidase, cytosolic III-like 69.11(n)
    65.16(a)
      420034  NM_001006334.1  NP_001006334.1 
    lizard
    (Anolis carolinensis)
    Reptilia NT5C3B6
    5'-nucleotidase, cytosolic IIIB
    64(a)
    1 ↔ 1
    6(66572145-66587311)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3985532 similar to 5'-nucleotidase, cytosolic III 75.28(n)    BC046729.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG33621 CG3362 52.36(n)
    39.53(a)
      37875  NM_138051.3  NP_611895.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y10G11A.16
    F25B5.36
    Protein F25B5.3, isoform b
    36(a)
    28(a)
    many ↔ many
    many ↔ many
    IV(16424650-16429897) WBGene00012423
    III(5948890-5953571) WBGene00017775
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G386801 AT2G38680 48.5(n)
    38.72(a)
      818450  NM_129425.4  NP_181402.4 
    rice
    (Oryza sativa)
    Liliopsida Os03g06489001 Os03g0648900 49.49(n)
    42.05(a)
      4333582  NM_001057316.1  NP_001050781.2 


    ENSEMBL Gene Tree for NT5C3B (if available)
    TreeFam Gene Tree for NT5C3B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NT5C3B gene
    NT5C3A2  
    1 SIMAP similar gene for NT5C3B using alignment to 6 protein entries:     5NT3B_HUMAN (see all proteins):
    NT5C3A

    NT5C3B for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NT5C3B (see all 263)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs99072441,2
    C,F,H--39980900(+) AACACC/TGCAGG 3 -- int127Minor allele frequency- N:0.00EA NA NS WA 2978
    rs1843018451,2
    --39980955(+) GGCTCC/TTCAGG 3 -- int10--------
    rs1908258481,2
    C--39980976(+) TAACGA/CAAGAC 3 -- int10--------
    rs1820124061,2
    --39981117(+) TAGGGA/GGACAG 3 -- int10--------
    rs14364401,2
    C,F,A,H--39981131(+) CACACA/GAATGC 3 -- int114Minor allele frequency- G:0.20NA WA CSA EA 377
    rs340883341,2
    C,F--39981136(+) GAATGC/TATCCC 3 -- int14Minor allele frequency- T:0.09NA WA 124
    rs1862278421,2
    --39981142(+) ATCCCC/TTCAGG 3 -- int10--------
    rs14364411,2
    C,F,A,H--39981248(+) CCACTG/ATAGGC 3 -- int129Minor allele frequency- A:0.11NS EA NA WA CSA 2446
    rs1413481011,2
    --39981296(+) GACACA/GATCAG 3 -- int10--------
    rs1890548201,2
    --39981326(+) TCAGGC/TCAATT 3 -- int10--------

    HapMap Linkage Disequilibrium report for NT5C3B (39981334 - 39992523 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NT5C3B: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NT5C3B
    DNA2.0 Custom Variant and Variant Library Synthesis for NT5C3B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for NT5C3B:    
    About MalaCards
    lynch syndrome    malaria


    NT5C3B for disorders           About GeneDecksing


    Export disorders for NT5C3B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NT5C3B gene integrated from 10 sources:
    (articles sorted by number of sources associating them with NT5C3B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of Drosophila and Human 7-Methyl GMP-specific Nucleotidases. (PubMed id 23223233)1, 2, 3 Buschmann J.... Wahle E. (J. Biol. Chem. 2013)
    2. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    3. Cytoskeletal scaffolding proteins interact with Lynch-Syndrome associated mismatch repair protein MLH1. (PubMed id 20706999)1 Brieger A....Trojan J. (Proteomics 2010)
    4. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (Science 2009)
    5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    6. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (Nature 2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 115024 HGNC: 28300 AceView: MGC20781 Ensembl:ENSG00000141698 euGenes: HUgn115024
    ECgene: NT5C3B Kegg: 115024 H-InvDB: NT5C3B

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for NT5C3B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for NT5C3B gene:
    Search GeneIP for patents involving NT5C3B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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