Aliases for NT5C3B Gene
External Ids for NT5C3B Gene
Previous HGNC Symbols for NT5C3B Gene
Previous GeneCards Identifiers for NT5C3B Gene
GeneCards Summary for NT5C3B Gene
NT5C3B (5'-Nucleotidase, Cytosolic IIIB) is a Protein Coding gene. Diseases associated with NT5C3B include lynch syndrome. Among its related pathways are Gene Expression and Metabolism. GO annotations related to this gene include nucleotide binding and 5-nucleotidase activity. An important paralog of this gene is NT5C3A.
UniProtKB/Swiss-Prot for NT5C3B Gene
Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233).