Aliases for NT5C3B Gene
External Ids for NT5C3B Gene
Previous HGNC Symbols for NT5C3B Gene
Previous GeneCards Identifiers for NT5C3B Gene
GeneCards Summary for NT5C3B Gene
NT5C3B (5'-Nucleotidase, Cytosolic IIIB) is a Protein Coding gene. Diseases associated with NT5C3B include Lynch Syndrome. Among its related pathways are Purine metabolism (KEGG) and Nicotinate and nicotinamide metabolism. GO annotations related to this gene include nucleotide binding and 5-nucleotidase activity. An important paralog of this gene is NT5C3A.
UniProtKB/Swiss-Prot for NT5C3B Gene
Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233).