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Aliases for NT5C1B-RDH14 Gene

Aliases for NT5C1B-RDH14 Gene

  • NT5C1B-RDH14 Readthrough 2 3 5

External Ids for NT5C1B-RDH14 Gene

Previous GeneCards Identifiers for NT5C1B-RDH14 Gene

  • GC02U902251
  • GC02M018737

Summaries for NT5C1B-RDH14 Gene

Entrez Gene Summary for NT5C1B-RDH14 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring NT5C1B (5'-nucleotidase, cytosolic IB) and RDH14 (retinol dehydrogenase 14) genes on chromosome 2. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Nov 2010]

GeneCards Summary for NT5C1B-RDH14 Gene

NT5C1B-RDH14 (NT5C1B-RDH14 Readthrough) is a Protein Coding gene. Among its related pathways are Metabolism and NAD metabolism. GO annotations related to this gene include nucleotide binding and magnesium ion binding. An important paralog of this gene is NT5C1B.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NT5C1B-RDH14 Gene

Genomics for NT5C1B-RDH14 Gene

Regulatory Elements for NT5C1B-RDH14 Gene

Enhancers for NT5C1B-RDH14 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around NT5C1B-RDH14 on UCSC Golden Path with GeneCards custom track

Genomic Location for NT5C1B-RDH14 Gene

18,554,723 bp from pter
18,589,580 bp from pter
34,858 bases
Minus strand

Genomic View for NT5C1B-RDH14 Gene

Genes around NT5C1B-RDH14 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NT5C1B-RDH14 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NT5C1B-RDH14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NT5C1B-RDH14 Gene

Proteins for NT5C1B-RDH14 Gene

  • Protein details for NT5C1B-RDH14 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein NT5C1B-RDH14
    Protein Accession:

    Protein attributes for NT5C1B-RDH14 Gene

    533 amino acids
    Molecular mass:
    60169 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NT5C1B-RDH14 Gene

Proteomics data for NT5C1B-RDH14 Gene at MOPED

Post-translational modifications for NT5C1B-RDH14 Gene

No Post-translational modifications

Other Protein References for NT5C1B-RDH14 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NT5C1B-RDH14 Gene

Domains & Families for NT5C1B-RDH14 Gene

Protein Domains for NT5C1B-RDH14 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with NT5C1B-RDH14: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NT5C1B-RDH14 Gene

Function for NT5C1B-RDH14 Gene

Phenotypes for NT5C1B-RDH14 Gene

genes like me logo Genes that share phenotypes with NT5C1B-RDH14: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NT5C1B-RDH14 Gene

Localization for NT5C1B-RDH14 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NT5C1B-RDH14 Gene

Pathways & Interactions for NT5C1B-RDH14 Gene

genes like me logo Genes that share pathways with NT5C1B-RDH14: view

Pathways by source for NT5C1B-RDH14 Gene

Interacting Proteins for NT5C1B-RDH14 Gene

Gene Ontology (GO) - Biological Process for NT5C1B-RDH14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009117 nucleotide metabolic process IEA --
genes like me logo Genes that share ontologies with NT5C1B-RDH14: view

No data available for SIGNOR curated interactions for NT5C1B-RDH14 Gene

Drugs & Compounds for NT5C1B-RDH14 Gene

No Compound Related Data Available

Transcripts for NT5C1B-RDH14 Gene

mRNA/cDNA for NT5C1B-RDH14 Gene

(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NT5C1B-RDH14 Gene

No ASD Table

Relevant External Links for NT5C1B-RDH14 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NT5C1B-RDH14 Gene

mRNA expression in normal human tissues for NT5C1B-RDH14 Gene

genes like me logo Genes that share expression patterns with NT5C1B-RDH14: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for NT5C1B-RDH14 Gene

Orthologs for NT5C1B-RDH14 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NT5C1B-RDH14 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 69 (a)
(Canis familiaris)
Mammalia -- 36
  • 52 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 53 (a)
(Mus musculus)
Mammalia Nt5c1b 36
  • 71 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 55 (a)
(Pan troglodytes)
Mammalia NT5C1B-RDH14 36
  • 98 (a)
(Gallus gallus)
Aves -- 36
  • 68 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 67 (a)
(Danio rerio)
Actinopterygii CABZ01003826.1 36
  • 31 (a)
nt5c1ba 36
  • 57 (a)
nt5c1bb 36
  • 62 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 54 (a)
Species with no ortholog for NT5C1B-RDH14:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NT5C1B-RDH14 Gene

Gene Tree for NT5C1B-RDH14 (if available)
Gene Tree for NT5C1B-RDH14 (if available)

Paralogs for NT5C1B-RDH14 Gene

Paralogs for NT5C1B-RDH14 Gene

(5) SIMAP similar genes for NT5C1B-RDH14 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with NT5C1B-RDH14: view

Variants for NT5C1B-RDH14 Gene

Structural Variations from Database of Genomic Variants (DGV) for NT5C1B-RDH14 Gene

Variant ID Type Subtype PubMed ID
esv2751837 CNV Gain 17911159
nsv2624 CNV Insertion 18451855
esv2229780 CNV Deletion 18987734
nsv519085 CNV Loss 19592680

Variation tolerance for NT5C1B-RDH14 Gene

Residual Variation Intolerance Score: 92.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.45; 64.08% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Relevant External Links for NT5C1B-RDH14 Gene

Disorders for NT5C1B-RDH14 Gene

Relevant External Links for NT5C1B-RDH14

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for NT5C1B-RDH14 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NT5C1B-RDH14 Gene

Publications for NT5C1B-RDH14 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for NT5C1B-RDH14 Gene

Sources for NT5C1B-RDH14 Gene