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Aliases for NT5C1B-RDH14 Gene

Aliases for NT5C1B-RDH14 Gene

  • NT5C1B-RDH14 Readthrough 2 3

External Ids for NT5C1B-RDH14 Gene

Previous GeneCards Identifiers for NT5C1B-RDH14 Gene

  • GC02U902251
  • GC02M018737

Summaries for NT5C1B-RDH14 Gene

Entrez Gene Summary for NT5C1B-RDH14 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring NT5C1B (5'-nucleotidase, cytosolic IB) and RDH14 (retinol dehydrogenase 14) genes on chromosome 2. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Nov 2010]

GeneCards Summary for NT5C1B-RDH14 Gene

NT5C1B-RDH14 (NT5C1B-RDH14 Readthrough) is a Protein Coding gene. Among its related pathways are Metabolism and Nicotinate and nicotinamide metabolism. An important paralog of this gene is NT5C1A.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NT5C1B-RDH14 Gene

Genomics for NT5C1B-RDH14 Gene

Genomic Location for NT5C1B-RDH14 Gene

18,554,723 bp from pter
18,589,580 bp from pter
34,858 bases
Minus strand

Genomic View for NT5C1B-RDH14 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NT5C1B-RDH14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NT5C1B-RDH14 Gene

No data available for Regulatory Elements for NT5C1B-RDH14 Gene

Proteins for NT5C1B-RDH14 Gene

  • Protein details for NT5C1B-RDH14 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein NT5C1B-RDH14
    Protein Accession:
    Secondary Accessions:

    Protein attributes for NT5C1B-RDH14 Gene

    533 amino acids
    Molecular mass:
    60169 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NT5C1B-RDH14 Gene

Proteomics data for NT5C1B-RDH14 Gene at MOPED

Post-translational modifications for NT5C1B-RDH14 Gene

No Post-translational modifications

Other Protein References for NT5C1B-RDH14 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NT5C1B-RDH14 Gene

Domains for NT5C1B-RDH14 Gene

Protein Domains for NT5C1B-RDH14 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with NT5C1B-RDH14: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for NT5C1B-RDH14 Gene

Function for NT5C1B-RDH14 Gene

Gene Ontology (GO) - Molecular Function for NT5C1B-RDH14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding --
GO:0000287 magnesium ion binding --
GO:0008253 5-nucleotidase activity --
GO:0016491 oxidoreductase activity --
genes like me logo Genes that share ontologies with NT5C1B-RDH14: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NT5C1B-RDH14 Gene

Localization for NT5C1B-RDH14 Gene

Gene Ontology (GO) - Cellular Components for NT5C1B-RDH14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm --
genes like me logo Genes that share ontologies with NT5C1B-RDH14: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for NT5C1B-RDH14 Gene

Pathways for NT5C1B-RDH14 Gene

genes like me logo Genes that share pathways with NT5C1B-RDH14: view

Pathways by source for NT5C1B-RDH14 Gene

Interacting Proteins for NT5C1B-RDH14 Gene

Gene Ontology (GO) - Biological Process for NT5C1B-RDH14 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process --
GO:0009117 nucleotide metabolic process --
GO:0016311 dephosphorylation --
genes like me logo Genes that share ontologies with NT5C1B-RDH14: view

Transcripts for NT5C1B-RDH14 Gene

mRNA/cDNA for NT5C1B-RDH14 Gene

(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NT5C1B-RDH14 Gene

No ASD Table

Relevant External Links for NT5C1B-RDH14 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NT5C1B-RDH14 Gene

mRNA expression in normal human tissues for NT5C1B-RDH14 Gene

genes like me logo Genes that share expressions with NT5C1B-RDH14: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for NT5C1B-RDH14 Gene

Orthologs for NT5C1B-RDH14 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NT5C1B-RDH14 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 69 (a)
(Canis familiaris)
Mammalia -- 36
  • 52 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 53 (a)
(Mus musculus)
Mammalia Nt5c1b 36
  • 71 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 55 (a)
(Pan troglodytes)
Mammalia NT5C1B-RDH14 36
  • 98 (a)
(Gallus gallus)
Aves -- 36
  • 68 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 67 (a)
(Danio rerio)
Actinopterygii CABZ01003826.1 36
  • 31 (a)
nt5c1ba 36
  • 57 (a)
nt5c1bb 36
  • 62 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 54 (a)
Species with no ortholog for NT5C1B-RDH14:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NT5C1B-RDH14 Gene

Gene Tree for NT5C1B-RDH14 (if available)
Gene Tree for NT5C1B-RDH14 (if available)

Paralogs for NT5C1B-RDH14 Gene

Paralogs for NT5C1B-RDH14 Gene

(5) SIMAP similar genes for NT5C1B-RDH14 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with NT5C1B-RDH14: view

Variants for NT5C1B-RDH14 Gene

Structural Variations from Database of Genomic Variants (DGV) for NT5C1B-RDH14 Gene

Variant ID Type Subtype PubMed ID
esv2751837 CNV Gain 17911159
nsv2624 CNV Insertion 18451855
esv2229780 CNV Deletion 18987734
nsv519085 CNV Loss 19592680

Relevant External Links for NT5C1B-RDH14 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for NT5C1B-RDH14 Gene

Disorders for NT5C1B-RDH14 Gene

No disorders were found for NT5C1B-RDH14 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for NT5C1B-RDH14 Gene

Publications for NT5C1B-RDH14 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  2. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3
  3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PMID: 23000965) Povlsen L.K. … Choudhary C. (Nat. Cell Biol. 2012) 3

Products for NT5C1B-RDH14 Gene

Sources for NT5C1B-RDH14 Gene

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