NT5C1B-RDH14 Gene
protein-coding GIFtS: 21
GCID: GC02M018737
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NT5C1B-RDH14 readthrough
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Aliases
for NT5C1B-RDH14 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| NT5C1B-RDH14 Readthrough1 2 | | NT5C1B-RDH14 Protein2 | | NT5C1B-RDH14 Read-Through Transcript2 |
Export aliases for NT5C1B-RDH14 gene to outside databasesPrevious GC identifer: GC02U902251 |
Summaries
for NT5C1B-RDH14 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NT5C1B-RDH14:
This locus represents naturally occurring read-through transcription between the neighboring NT5C1B (5'-nucleotidase,cytosolic IB) and RDH14 (retinol dehydrogenase 14) genes on chromosome 2. Alternative splicing results in multipletranscript variants, one of which encodes a fusion protein that shares sequence identity with the products of eachindividual gene. (provided by RefSeq, Nov 2010)
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Genomic Views
for NT5C1B-RDH14 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for NT5C1B-RDH14
Other transcription factors
Search SABiosciences Chromatin IP Primers for NT5C1B-RDH14
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NT5C1B-RDH14 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p Ensembl cytogenetic band: 2p24.2 HGNC cytogenetic band: 2p24.2NT5C1B-RDH14 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M018737: view genomic region
(about GC identifiers)
Start:
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18,736,811 bp from pter |
End:
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18,770,830 bp from pter |
Size:
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34,020 bases |
Orientation:
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minus strand |
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Proteins
for NT5C1B-RDH14 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/TrEMBL: C9J2C7 (See
protein sequence)Recommended Name: Protein NT5C1B-RDH14 Size: 533 amino acids; 60169 Da
Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered aspreliminary dataNT5C1B-RDH14 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins (2 alternative transcripts):
NP_001186032.1 NP_001186033.1
ENSEMBL proteins: ENSP00000433415 ENSP00000412639
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0005737 | cytoplasm |
-- | -- |
NT5C1B-RDH14 for ontologies About GeneDecksing
NT5C1B-RDH14 Antibody Products:
Assay Products for NT5C1B-RDH14: |
Protein
Domains /
Families
for NT5C1B-RDH14 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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NT5C1B-RDH14 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry C9J2C7ProtoNet protein and cluster: C9J2C7 |
Function
for NT5C1B-RDH14 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5C1B-RDH14 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
NT5C1B-RDH14 for ontologies About GeneDecksing
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Pathways & Interactions
for NT5C1B-RDH14 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NT5C1B-RDH14
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0009117 | nucleotide metabolic process |
-- | -- |
NT5C1B-RDH14 for ontologies About GeneDecksing
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Drugs & Compounds
for NT5C1B-RDH14 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NT5C1B-RDH14
Search CenterWatch for drugs/clinical trials and news about NT5C1B-RDH14 
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Transcripts
for NT5C1B-RDH14 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for NT5C1B-RDH14 gene (2 alternative transcripts): NM_001199103.1 NM_001199104.1 2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000532967(uc002rcy.3) ENST00000444297(uc010exr.3)
GeneLoc Exon Structure
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Expression
for NT5C1B-RDH14 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NT5C1B-RDH14 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image SABiosciences Custom PCR Arrays for NT5C1B-RDH14
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat NT5C1B-RDH14 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NT5C1B-RDH14 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NT5C1B-RDH14 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5C1B-RDH14 |
Orthologs
for NT5C1B-RDH14 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for NT5C1B-RDH14 gene from 3/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
NT5C1B6 |
Uncharacterized protein |
68(a) |
1 → many |
3(103451715-103457412) |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
66(a) |
1 → many |
1(153749165-153761486) |
zebrafish
(Danio rerio) |
Actinopterygii |
nt5c1bb6nt5c1ba6 |
5'-nucleotidase, cytosolic IB a |
62(a)57(a) |
many ↔ manymany ↔ many |
20(9455842-9478934) 13(32669771-32677534) |
ENSEMBL Gene Tree for NT5C1B-RDH14 (if available)
TreeFam Gene Tree for NT5C1B-RDH14 (if available) |
Paralogs
for NT5C1B-RDH14 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NT5C1B-RDH14 gene
- NT5C1A2 NT5C1B2
5 SIMAP similar genes for NT5C1B-RDH14 using alignment to 1 protein entry: C9J2C7_HUMAN:DHRSX NT5C1A RDH11 NT5C1B RDH14
NT5C1B-RDH14 for paralogs About GeneDecksing
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Genomic Variants
for NT5C1B-RDH14 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for NT5C1B-RDH14 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for NT5C1B-RDH14 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for NT5C1B-RDH14 gene integrated from 9 sources:
(articles sorted by number of sources associating them with NT5C1B-RDH14) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PubMed id 20967262)1 Prakash T....Taylor T.D. (2010)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
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External Searches for NT5C1B-RDH14 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing NT5C1B-RDH14 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing NT5C1B-RDH14 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NT5C1B-RDH14 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
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About This Section
| Patent Information for NT5C1B-RDH14 gene:
Search GeneIP for patents involving NT5C1B-RDH14
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for NT5C1B-RDH14 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NT5C1B-RDH14 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NT5C1B-RDH14 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NT5C1B-RDH14 | | | Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NT5C1B-RDH14 | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NT5C1B-RDH14 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NT5C1B-RDH14 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5C1B-RDH14 |
|  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat NT5C1B-RDH14 |
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