Aliases for NT5C1A Gene
External Ids for NT5C1A Gene
Previous GeneCards Identifiers for NT5C1A Gene
Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008]
GeneCards Summary for NT5C1A Gene
NT5C1A (5'-Nucleotidase, Cytosolic IA) is a Protein Coding gene. Diseases associated with NT5C1A include Inclusion Body Myositis and Crigler-Najjar Syndrome, Type I. Among its related pathways are Metabolism and Purine metabolism. GO annotations related to this gene include nucleotide binding and 5-nucleotidase activity. An important paralog of this gene is NT5C1B.
UniProtKB/Swiss-Prot for NT5C1A Gene
Dephosphorylates the 5 and 2(3)-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.