Aliases for NT5C1A Gene
External Ids for NT5C1A Gene
Previous GeneCards Identifiers for NT5C1A Gene
Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008]
GeneCards Summary for NT5C1A Gene
NT5C1A (5'-Nucleotidase, Cytosolic IA) is a Protein Coding gene. Diseases associated with NT5C1A include Inclusion Body Myositis and Myositis. Among its related pathways are Purine metabolism and Integrated Pancreatic Cancer Pathway. GO annotations related to this gene include nucleotide binding and 5-nucleotidase activity. An important paralog of this gene is NT5C1B.
UniProtKB/Swiss-Prot for NT5C1A Gene
Dephosphorylates the 5 and 2(3)-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.