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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NT5C1A Gene

protein-coding   GIFtS: 56
GCID: GC01M040154

5'-Nucleotidase, Cytosolic IA

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
5'-Nucleotidase, Cytosolic IA1 2     CN1A2
Cytosolic 5'-Nucleotidase IA1 2 3     CNI2
AMP-Specific 5'-NT1 2     Cytosolic 5' Nucleotidase, Type 1A2
Cytosolic 5' Nucleotidase1     Cytosolic 5'-Nucleotidase 1A2
Type 1A1     EC 3.1.3.53
CN-I2     cN-I3
CN-IA2     cN-IA3
CN12     cN1A3

External Ids:    HGNC: 178191   Entrez Gene: 846182   Ensembl: ENSG000001169817   OMIM: 6105255   UniProtKB: Q9BXI33   

Export aliases for NT5C1A gene to outside databases

Previous GC identifers: GC01M039128 GC01M039588 GC01M039538 GC01M039793 GC01M039897 GC01M038243


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NT5C1A Gene:
Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 (PubMed
11133996)).(supplied by OMIM, Mar 2008)

GeneCards Summary for NT5C1A Gene: 
NT5C1A (5'-nucleotidase, cytosolic IA) is a protein-coding gene. Diseases associated with NT5C1A include crigler-najjar syndrome, and metabolic disorders, and among its related super-pathways are Purine metabolism and NAD metabolism. GO annotations related to this gene include 5'-nucleotidase activity and nucleotide binding. An important paralog of this gene is NT5C1B-RDH14.

UniProtKB/Swiss-Prot: 5NT1A_HUMAN, Q9BXI3
Function: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate
specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NT5C1A gene promoter:
         POU2F2 (Oct-2.1)   Oct-B1   oct-B3   Sp1   oct-B2   POU2F2   POU2F2C   POU2F1   POU2F1a   POU2F2B   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNT5C1A promoter sequence
   Search SABiosciences Chromatin IP Primers for NT5C1A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NT5C1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.3-p33   Ensembl cytogenetic band:  1p34.2   HGNC cytogenetic band: 1p34.3-p33

NT5C1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NT5C1A gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M040154:  view genomic region     (about GC identifiers)

Start:
40,124,793 bp from pter      End:
40,137,710 bp from pter
Size:
12,918 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: 5NT1A_HUMAN, Q9BXI3 (See protein sequence)
Recommended Name: Cytosolic 5'-nucleotidase 1A  
Size: 368 amino acids; 41021 Da
Cofactor: Magnesium
Subcellular location: Cytoplasm
Secondary accessions: Q3SYB9 Q5TG98 Q9BWT8

Explore the universe of human proteins at neXtProt for NT5C1A: NX_Q9BXI3

Explore proteomics data for NT5C1A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BXI3

  • NT5C1A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NT5C1A Protein Expression
    REFSEQ proteins: NP_115915.1  
    ENSEMBL proteins: 
     ENSP00000235628  
    Reactome Protein details: Q9BXI3
    Human Recombinant Protein Products for NT5C1A: 
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    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005829cytosol TAS--

    NT5C1A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: 5a-nucleotidase IA 
    Adenosine turnover

    1 InterPro protein domain:
     IPR010394 5-nucleotidase

    Graphical View of Domain Structure for InterPro Entry Q9BXI3

    ProtoNet protein and cluster: Q9BXI3

    1 Blocks protein domain: IPB010394 5-nucleotidase

    UniProtKB/Swiss-Prot: 5NT1A_HUMAN, Q9BXI3
    Similarity: Belongs to the 5'-nucleotidase type 3 family


    NT5C1A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: 5NT1A_HUMAN, Q9BXI3
    Function: Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate
    specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia
    Catalytic activity: A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate
    Enzyme regulation: Activated by ADP

         Enzyme Number (IUBMB): EC 3.1.3.51

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0000287magnesium ion binding IEA--
    GO:00082535'-nucleotidase activity NAS11133996
         
    NT5C1A for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NT5C1A 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for NT5C1A About   (see all 7)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Purine metabolism
    Purine metabolism0.38
    ATP/ITP metabolism0.31
    Pyrimidine metabolism0.38
    2NAD metabolism
    NAD metabolism0.43
    Nicotinate and nicotinamide metabolism0.43
    3Metabolism
    Metabolism0.40
    Metabolic pathways0.40
    4Purine metabolism
    Purine metabolism0.42
    Purine catabolism0.30
    Metabolism of nucleotides0.42
    5purine nucleotides degradation II (aerobic)
    purine nucleotides degradation II (aerobic)0.67
    adenosine nucleotides degradation II0.67

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 EMD Millipore Pathways for NT5C1A
        NAD metabolism
    ATP/ITP metabolism


    2 GeneGo (Thomson Reuters) Pathways for NT5C1A
        NAD metabolism
    ATP/ITP metabolism

    3 BioSystems Pathways for NT5C1A
        Integrated Pancreatic Cancer Pathway
    adenosine nucleotides degradation II
    purine nucleotides degradation II (aerobic)


    5/6        Reactome Pathways for NT5C1A (see all 6)
        Metabolism of nucleotides
    Metabolism
    Purine catabolism
    Purine metabolism
    Pyrimidine catabolism


    4         Kegg Pathways  (Kegg details for NT5C1A):
        Purine metabolism
    Pyrimidine metabolism
    Nicotinate and nicotinamide metabolism
    Metabolic pathways


    NT5C1A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NT5C1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/77 Interacting proteins for NT5C1A (ENSP000002356284) via UniProtKB, MINT, STRING, and/or I2D (see all 77)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADAENSP000003619654STRING: ENSP00000361965
    ADKENSP000002866214STRING: ENSP00000286621
    ADSLENSP000002161944STRING: ENSP00000216194
    ADSSENSP000003554934STRING: ENSP00000355493
    AMPD1ENSP000003165204STRING: ENSP00000316520
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006144purine nucleobase metabolic process TAS--
    GO:0006195purine nucleotide catabolic process TAS--
    GO:0006206pyrimidine nucleobase metabolic process TAS--
    GO:0009116nucleoside metabolic process NAS11133996
    GO:0009117nucleotide metabolic process ----

    NT5C1A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    NT5C1A for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for NT5C1A (5NT1A)

    10/28 HMDB Compounds for NT5C1A (see all 28)    About this table
    CompoundSynonyms CAS #PubMed Ids
    2'-Deoxyguanosine 5'-monophosphate2'-Deoxy-5'-GMP (see all 21)902-04-5--
    5-Thymidylic acid2'-Deoxythymidine 5'-monophosphate (see all 28)365-07-1--
    Adenosine1-(6-amino-9H-purin-9-yl)-1-deoxy-beta-D-Ribofuranose (see all 32)58-61-7--
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    Cytidine1-(b-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine (see all 20)65-46-3--
    Cytidine monophosphate5'-CMP (see all 14)63-37-6--
    Deoxyadenosine1-(6-amino-9H-purin-9-yl)-1,2-dideoxy-b-D-Ribofuranose (see all 22)958-09-8--
    Deoxyadenosine monophosphate2'-Deoxy-5'-adenylate (see all 24)653-63-4--
    Deoxycytidine1-(2-Deoxy-b-D-ribofuranosyl)cytosine (see all 15)951-77-9--
    Deoxyguanosine2'-Deoxyguanosine (see all 11)961-07-9--

    1 Novoseek inferred chemical compound relationship for NT5C1A gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nucleoside 50.4 2 11133996 (2)

    Search CenterWatch for drugs/clinical trials and news about NT5C1A / 5NT1A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NT5C1A gene: 
    NM_032526.1  

    Unigene Cluster for NT5C1A:

    5'-nucleotidase, cytosolic IA
    Hs.307006  [show with all ESTs]
    Unigene Representative Sequence: BC103879
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000235628(uc001cdq.1)
    miRNA
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    Additional mRNA sequence: 

    AF331801.1 AY028778.1 BC103879.1 BC103880.1 

    1 DOTS entry:

    DT.91803821 

    5 AceView cDNA sequences:

    AY028778 NM_032526 AF331801 CD634073 CD634072 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NT5C1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCCTTATGG
    NT5C1A Expression
    About this image


    See NT5C1A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NT5C1A

    SOURCE GeneReport for Unigene cluster: Hs.307006

    UniProtKB/Swiss-Prot: 5NT1A_HUMAN, Q9BXI3
    Tissue specificity: Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney
    and pancreas

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NT5C1A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for NT5C1A gene from 5/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nt5c1a1 , 5 5'-nucleotidase, cytosolic IA1, 5 89.22(n)1
    95.62(a)1
      4 (57.40 cM)5
    2307181  NM_001085502.11  NP_001078971.11 
     1232015045 
    chicken
    (Gallus gallus)
    Aves NT5C1A1 5'-nucleotidase, cytosolic IA 79.58(n)
    85.19(a)
      419675  XM_417822.3  XP_417822.2 
    lizard
    (Anolis carolinensis)
    Reptilia NT5C1A6
    --
    --
    79(a)
    42(a)
    1 ↔ 1
    possible ortholog
    GL343481.1(207438-221710)
    1(70773322-70792550)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.87992 Xenopus laevis transcribed sequence with moderate similarity more 83.1(n)    BJ066298.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570917492   -- 74.47(n)    57091749 


    ENSEMBL Gene Tree for NT5C1A (if available)
    TreeFam Gene Tree for NT5C1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NT5C1A gene
    NT5C1B-RDH142  NT5C1B2  
    2 SIMAP similar genes for NT5C1A using alignment to 1 protein entry:     5NT1A_HUMAN:
    NT5C1B    NT5C1B-RDH14

    NT5C1A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/326 SNPs in NT5C1A are shown (see all 326)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1113729891,2
    F--40124409(+) GGACAG/TAGCTT 1 -- ds50011Minor allele frequency- T:0.50CSA 2
    rs1817105361,2
    --40124483(+) CTAAGC/TCACTA 1 -- ds50010--------
    rs1401416171,2
    --40124566(+) TGCACA/TGTCCT 1 -- ds50010--------
    rs1420064221,2
    --40124657(+) CTACAA/GGTACA 1 -- ds50010--------
    rs1435733201,2
    C--40124729(+) TACCA-/GAGGAGGT 1 -- ds50010--------
    rs1124212791,2
    C,F--40124804(+) TGCAGA/CTGGGG 2 A S mis12Minor allele frequency- C:0.01CSA NA 4554
    rs1456468431,2
    C,F--40124934(+) TGTGGG/ACGGAT 2 /R syn11Minor allele frequency- A:0.00NA 4546
    rs1903444711,2
    C--40124935(+) GTGGGC/TGGATC 2 H R mis11Minor allele frequency- T:0.00EU 1207
    rs2003577101,2
    C--40125035(+) GGCCCC/TGGAAC 2 R G mis10--------
    rs412645071,2
    C--40125053(+) ACTGCA/GTGCTG 2 R C mis10--------

    HapMap Linkage Disequilibrium report for NT5C1A (40124793 - 40137710 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for NT5C1A:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv577CNV Insertion18451855
    esv2530832CNV Insertion19546169
    nsv7177OTHER Inversion18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610525    OMIM disorders: --

    9 diseases for NT5C1A:    About MalaCards
    crigler-najjar syndrome    metabolic disorders    lateral sclerosis    hypoxia
    amyotrophic lateral sclerosis    infertility    ischemia    pancreatic cancer
    pancreatitis

    1 disease from the University of Copenhagen DISEASES database for NT5C1A:
    Bilirubin metabolic disorder

    NT5C1A for disorders           About GeneDecksing

    Genetic Association Database (GAD): NT5C1A

    Export disorders for NT5C1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NT5C1A gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with NT5C1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human cytosolic 5'-nucleotidase I: characterization and role in nucleoside analog resistance. (PubMed id 11133996)1, 2, 3, 9 Hunsucker S.A.... Mitchell B.S. (2001)
    2. Cloning of a mouse cytosolic 5'-nucleotidase-I identifies a new gene related to human autoimmune infertility-related protein. (PubMed id 11690631)1, 3, 9 Sala-Newby G.B. and Newby A.C. (2001)
    3. Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis. (PubMed id 19451621)1, 4 Landers J.E....Brown R.H. (2009)
    4. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Expression of cytosolic 5' nucleotidase does not correlate with expression of oxidative metabolism marker: myoglobine in human skeletal muscles. (PubMed id 19352542)1, 9 Lechward K. and Tkacz-Stachowska K. (2009)
    7. Suppression of 5'-nucleotidase enzymes promotes AMP-a ctivated protein kinase (AMPK) phosphorylation and metabolism in human and mous e skeletal muscle. (PubMed id 21873433)1 Kulkarni S.S....Zierath J.R. (2011)
    8. Cell cycle dependent regulation of deoxycytidine kinase, deoxyguanosine kinase, and cytosolic 5'-nucleotidase I activity in MOLT-4 cells. (PubMed id 17065091)1 Fyrberg A....Lotfi K. (2006)
    9. Expression of human ecto-5'-nucleotidase in pig endothelium increases adenosine production and protects from NK cell-mediated lysis. (PubMed id 15888028)1 Osborne F.N....Smolenski R.T. (2005)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84618 HGNC: 17819 AceView: NT5C1A Ensembl:ENSG00000116981 euGenes: HUgn84618
    ECgene: NT5C1A Kegg: 84618 H-InvDB: NT5C1A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NT5C1A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NT5C1A gene:
    Search GeneIP for patents involving NT5C1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 27 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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