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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NSUN6 Gene

protein-coding   GIFtS: 48
GCID: GC10M018874

NOP2/Sun Domain Family, Member 6

(Previous names: NOL1/NOP2/Sun domain family 6, NOL1/NOP2/Sun domain family,...)
(Previous symbol: NOPD1)
Microbiology & Infectious Diseases Congress
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
NOP2/Sun Domain Family, Member 61 2     4933414E04Rik2
NOPD11 2 3     Nucleolar Protein (NOL1/NOP2/Sun) And PUA Domains 12
NOL1/NOP2/Sun Domain Family 61 2     Putative Methyltransferase NSUN62
NOL1/NOP2/Sun Domain Family, Member 61 2     EC 2.1.1.-3
NOL1/NOP2/Sun And PUA Domain-Containing Protein 12 3     EC 2.1.18
NOL1/NOP2/Sun Domain Family Member 62 3     EC 2.1.1.528

External Ids:    HGNC: 235291   Entrez Gene: 2210782   Ensembl: ENSG000002410587   UniProtKB: Q8TEA13   

Export aliases for NSUN6 gene to outside databases

Previous GC identifer: GC10M018499


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for NSUN6 Gene: 
NSUN6 (NOP2/Sun domain family, member 6) is a protein-coding gene. Diseases associated with NSUN6 include pneumonia. GO annotations related to this gene include methyltransferase activity and RNA binding. An important paralog of this gene is NOP2.

UniProtKB/Swiss-Prot: NSUN6_HUMAN, Q8TEA1
Function: May have S-adenosyl-L-methionine-dependent methyl-transferase activity (Potential)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_008705.16  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NSUN6 gene promoter:
         Oct-B1   oct-B3   oct-B2   AML1a   p53   CREB   POU2F1   deltaCREB   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNSUN6 promoter sequence
   Search SABiosciences Chromatin IP Primers for NSUN6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NSUN6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10p12.31   Ensembl cytogenetic band:  10p12.31   HGNC cytogenetic band: 10p13

NSUN6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NSUN6 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M018874:  view genomic region     (about GC identifiers)

Start:
18,834,264 bp from pter      End:
18,940,551 bp from pter
Size:
106,288 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NSUN6_HUMAN, Q8TEA1 (See protein sequence)
Recommended Name: Putative methyltransferase NSUN6  
Size: 469 amino acids; 51770 Da
Secondary accessions: B0YJ54

Explore the universe of human proteins at neXtProt for NSUN6: NX_Q8TEA1

Explore proteomics data for NSUN6 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TEA1

  • 3 DME Specific Peptides for NSUN6 (Q8TEA1)
     CAAPGGK  LLDAPCS  VYSDIKG 

    NSUN6 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NSUN6 Protein Expression
    REFSEQ proteins: NP_872349.1  
    ENSEMBL proteins: 
     ENSP00000366519  

    Human Recombinant Protein Products for NSUN6: 
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    OriGene Protein Over-expression Lysate for NSUN6
    OriGene MassSpec for NSUN6 
    OriGene Custom Protein Services for NSUN6
    GenScript Custom Purified and Recombinant Proteins Services for NSUN6
    Novus Biologicals NSUN6 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NSUN6 


    NSUN6 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Assay Products for NSUN6: 
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NSUN6 
    Cloud-Clone Corp. CLIAs for NSUN6


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    NSUN: NOP2/Sun domain containing

    5 InterPro protein domains:
     IPR015947 PUA-like_domain
     IPR002478 PUA
     IPR023267 RCMT
     IPR001678 Fmu/NOL1/Nop2p
     IPR018314 Fmu/NOL1/Nop2p_CS

    Graphical View of Domain Structure for InterPro Entry Q8TEA1

    ProtoNet protein and cluster: Q8TEA1

    1 Blocks protein domain: IPB001678 Bacterial Sun/eukaryotic nucleolar Nop1/Nop2

    UniProtKB/Swiss-Prot: NSUN6_HUMAN, Q8TEA1
    Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family
    Similarity: Contains 1 PUA domain


    NSUN6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NSUN6_HUMAN, Q8TEA1
    Function: May have S-adenosyl-L-methionine-dependent methyl-transferase activity (Potential)

         Enzyme Numbers (IUBMB): EC 2.1.1.522 EC 2.1.1.-1 EC 2.1.12

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
    GO:0008168methyltransferase activity IEA--
         
    NSUN6 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for NSUN6:
     Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for NSUN6 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NSUN6

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NSUN6 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NSUN6 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NSUN6
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate NSUN6:
    hsa-miR-1207-3p hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidNSUN6 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NSUN6
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    Gene Editing
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    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for NSUN6 (see all 7)
    OriGene ORF clones in mouse, rat for NSUN6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NSUN6 (NM_182543)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NSUN6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NSUN6
    Sirion Biotech Customized lentivirus for stable overexpression of NSUN6 
                         Customized lentivirus expression plasmids for stable overexpression of NSUN6 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for NSUN6
    Search LifeMap BioReagents cell lines for NSUN6
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NSUN6


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NSUN6

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for NSUN6 (ENSP000003665194) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032259methylation ----

    NSUN6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NSUN6

    1 HMDB Compound for NSUN6    About this table
    CompoundSynonyms CAS #PubMed Ids
    S-Adenosylmethionine(3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine (see all 16)29908-03-0--

    Search CenterWatch for drugs/clinical trials and news about NSUN6

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NSUN6 gene: 
    NM_182543.2  

    Unigene Cluster for NSUN6:

    NOP2/Sun domain family, member 6
    Hs.396175  [show with all ESTs]
    Unigene Representative Sequence: NM_182543
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377304(uc010qcp.1) ENST00000493816
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NSUN6
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate NSUN6:
    hsa-miR-1207-3p hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidNSUN6 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for NSUN6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NSUN6
    Clone
    Products:
         
    OriGene clones in human, mouse for NSUN6 (see all 7)
    OriGene ORF clones in mouse, rat for NSUN6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NSUN6 (NM_182543)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NSUN6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NSUN6
    Sirion Biotech Customized lentivirus for stable overexpression of NSUN6 
                         Customized lentivirus expression plasmids for stable overexpression of NSUN6 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NSUN6
    OriGene qSTAR qPCR primer pairs in human, mouse for NSUN6
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NSUN6
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NSUN6
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NSUN6

    Additional mRNA sequence: 

    AK074323.1 BC035778.1 

    9 DOTS entries:

    DT.109194  DT.100773584  DT.100754687  DT.75105297  DT.121242760  DT.40260150  DT.97840028  DT.92068893 
    DT.95369380 

    24/92 AceView cDNA sequences (see all 92):

    BE549737 CR617827 AA625341 AW963619 AA909685 AL043071 AA347717 AI025186 
    BU156720 AA767779 AA749444 AI360426 AA437097 AW571854 AL698095 BX494216 
    AW183848 T03927 BI495854 BM543943 BQ708522 AA610808 AK098793 AA372695 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NSUN6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGCGTCTGG
    NSUN6 Expression
    About this image


    See NSUN6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NSUN6

    SOURCE GeneReport for Unigene cluster: Hs.396175
        SABiosciences Custom PCR Arrays for NSUN6
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for NSUN6
    OriGene qSTAR qPCR primer pairs in human, mouse for NSUN6
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    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NSUN6
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NSUN6
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NSUN6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NSUN6 gene from 9/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nsun61 , 5 NOL1/NOP2/Sun domain family member 61, 5 81.73(n)1
    81.24(a)1
      2 (10.94 cM)5
    744551  NM_001165941.11  NP_001159413.11 
     149951315 
    chicken
    (Gallus gallus)
    Aves NSUN61 NOP2/Sun domain family, member 6 73.88(n)
    73.66(a)
      428419  XM_425980.3  XP_425980.2 
    lizard
    (Anolis carolinensis)
    Reptilia NSUN66
    Uncharacterized protein
    66(a)
    1 ↔ 1
    6(17706374-17727480)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.167932 Xenopus laevis transcribed sequences 75.9(n)    BX853671.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1001495571 putative methyltransferase NSUN6-like 59.33(n)
    57.95(a)
      100149557  XM_001919312.3  XP_001919347.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG111091 CG11109 49.37(n)
    44.86(a)
      40507  NM_168974.1  NP_730761.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NOP26
    Probable RNA m(5)C methyltransferase, essential fo...
    15(a)
    1 → many
    XIV(510540-512396)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G065601 NOL1/NOP2/sun-like protein 49.96(n)
    42.05(a)
      837167  NM_100535.4  NP_172143.3 
    rice
    (Oryza sativa)
    Liliopsida Os.212862 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 71.97(n)    AK102062.1 


    ENSEMBL Gene Tree for NSUN6 (if available)
    TreeFam Gene Tree for NSUN6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NSUN6 gene
    NOP22  NSUN32  ENSG000002717862  NSUN42  

    NSUN6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2765 SNPs in NSUN6 are shown (see all 2765)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs746800651,2
    C--18498694(+) GAAGAC/TTGCTT 1 -- ds50010--------
    rs1441069511,2
    --18833798(+) AGCTAC/TGAAAT 1 -- ds50010--------
    rs1486935731,2
    --18833799(+) GCTATA/GAAATC 1 -- ds50010--------
    rs107645831,2
    C,F,A,H--18833812(+) GCCACT/CGCACT 1 -- ds500110Minor allele frequency- C:0.46NS NA CSA WA EA 406
    rs127643341,2
    C,F--18833841(+) CAAGAC/ACTTGT 1 -- ds50017Minor allele frequency- A:0.21WA NA EA 366
    rs673349601,2
    C--18833928(-) AGATC-/ATCCTTCG 1 -- ds50011Minor allele frequency- ATC:0.00NA 2
    rs118185101,2
    C,F,H--18834038(+) cttacG/Attcaa 1 -- ds500112Minor allele frequency- A:0.02NS EA NA WA 1308
    rs1422492961,2
    C--18834412(+) ACATAA/GTCAAT 1 -- ut310--------
    rs344076441,2
    C--18834658(+) AAAAA-/TCTTTT 1 -- ut311Minor allele frequency- T:0.00NA 2
    rs1885118551,2
    --18834739(+) GGCAGC/TCTTTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NSUN6 (18834264 - 18940551 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/17 variations for NSUN6 (see all 17):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2667049CNV Deletion23128226
    esv2661238CNV Deletion23128226
    esv2733739CNV Deletion23290073
    esv2670942CNV Deletion23128226
    esv1520077CNV Deletion17803354
    esv2446416CNV Deletion19546169
    esv2294866CNV Deletion18987734
    esv2664218CNV Deletion23128226
    nsv511455CNV Loss21212237
    nsv466760CNV Loss19166990

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NSUN6
    DNA2.0 Custom Variant and Variant Library Synthesis for NSUN6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for NSUN6:    About MalaCards
    pneumonia    


    NSUN6 for disorders           About GeneDecksing

    Genetic Association Database (GAD): NSUN6
    Human Genome Epidemiology (HuGE) Navigator: NSUN6 (2 documents)

    Export disorders for NSUN6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NSUN6 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with NSUN6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. An integrative method for scoring candidate genes fro m association studies: application to warfarin dosing. (PubMed id 21044367)1 Tatonetti N.P....Altman R.B. (2010)
    7. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (2009)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 221078 HGNC: 23529 AceView: NSUN6 Ensembl:ENSG00000241058 euGenes: HUgn221078
    ECgene: NSUN6 H-InvDB: NSUN6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NSUN6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NSUN6 gene:
    Search GeneIP for patents involving NSUN6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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