NSUN5P1 Gene
pseudogene GIFtS: 33
GCID: GC07P075039
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NOP2/Sun domain family, member 5 pseudogene 1(Previous names: NOL1/NOP2/Sun domain family, member 5B, NOP2/Sun domain...)
(Previous symbol: NSUN5B)
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Aliases
for NSUN5P1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| NOP2/Sun Domain Family, Member 5 Pseudogene 11 2 | | NOP2/Sun Domain Family, Member 5B1 | | NSUN5B1 2 3 | | NOP2/Sun Domain Family, Member 5B (Pseudogene)1 | | WBSCR20B1 2 3 | | NOP2/Sun Domain Family, Member 5B, Pseudogene1 | | NOL1/NOP2/Sun Domain Family, Member 5B1 | | Williams-Beuren Syndrome Chromosomal Region 20B Protein3 |
| External Ids: | HGNC: 191461 | Entrez Gene: 1554002 | Ensembl: ENSG000002237057 | UniProtKB: Q3KNT73 | | ORGUL members: | |
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| NONCODE:n409170 | |
Export aliases for NSUN5P1 gene to outside databasesPrevious GC identifer: GC07P074376
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Summaries
for NSUN5P1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NSUN5P1:
This gene shares high sequence similarity with the genes WBSCR20A and WBSCR20C; these three genes are the products ofgene duplication during evolution. Alternate transcriptional splice variants have been characterized. (provided byRefSeq, Feb 2010)
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Genomic Views
for NSUN5P1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079595.2
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for NSUN5P1
Other transcription factors
Search SABiosciences Chromatin IP Primers for NSUN5P1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NSUN5P1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q11.23 Ensembl cytogenetic band: 7q11.23 HGNC cytogenetic band: 7q11.23NSUN5P1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P075039: view genomic region
(about GC identifiers)
Start:
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75,039,605 bp from pter |
End:
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75,046,066 bp from pter |
Size:
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6,462 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 74,376,822-74,379,130 |
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Proteins
for NSUN5P1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/Swiss-Prot: NSN5B_HUMAN, Q3KNT7 (See
protein sequence)Recommended Name: Putative NOL1/NOP2/Sun domain family member 5B Size: 163 amino acids; 17679 Da
Caution: Could be the product of a pseudogene
Secondary accessions: B3KX24 Q52LC6 Q8N728Alternative splicing: 3 isoforms: Q3KNT7-1 Q3KNT7-2 Q3KNT7-3 Explore the universe of human proteins at neXtProt for NSUN5P1: NX_Q3KNT7
NSUN5P1 Protein expression data from MOPED and PaxDb: About this image 
Human Recombinant Protein Products:
NSUN5P1 Antibody Products:
Assay Products for NSUN5P1: |
Protein
Domains /
Families
for NSUN5P1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NSUN5P1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q3KNT7ProtoNet protein and cluster: Q3KNT7 UniProtKB/Swiss-Prot: NSN5B_HUMAN, Q3KNT7Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family |
Function
for NSUN5P1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NSUN5P1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NSUN5P1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for NSUN5P1 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NSUN5P1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NSUN5P1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NSUN5P1 |
|
Pathways & Interactions
for NSUN5P1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NSUN5P1
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Drugs & Compounds
for NSUN5P1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for NSUN5P1
Search CenterWatch for drugs/clinical trials and news about NSUN5P1
|
Transcripts
for NSUN5P1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NSUN5P1 gene (3 alternative transcripts): NM_001039575.1 NM_001039576.1 NM_145645.2 Unigene Cluster for NSUN5P1: NOP2/Sun domain family, member 5 pseudogene 1 Hs.436034 [show with all ESTs]Unigene Representative Sequence: AK1283749 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000473960 ENST00000393633 ENST00000457988 ENST00000455158 ENST00000421140
ENST00000422386 ENST00000464979 ENST00000428392(uc003udh.1) ENST00000427550
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NSUN5P1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NSUN5P1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for NSUN5P1 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NSUN5P1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NSUN5P1 |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NSUN5P1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat NSUN5P1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NSUN5P1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NSUN5P1 |
Additional cDNA sequence: AF416610.1 AK128374.1 BC044928.1 BC065512.1 BC080602.1 BC088379.1 BC093978.1 BC103750.1 BC107112.1 NR_033322.2 24/56 DOTS entries (see all 56): DT.100878795 DT.100059436 DT.95170473 DT.95221395 DT.92469777 DT.100878800 DT.121117011 DT.100670167 DT.121117021 DT.101971500 DT.121058065 DT.121117113 DT.121116955 DT.100059440 DT.121057923 DT.92471354 DT.102838696 DT.121116766 DT.121117038 DT.100878805 DT.121116606 DT.121116908 DT.121117132 DT.86845764 24/30 AceView cDNA sequences (see all 30): AI567828 AW152071 BM784311 BM784354 CB164817 AF416610 AI903942 BM741799 AI217271 AI740587 BM742756 AI521647 NM_145645 AI435115 AI355420 AK126486 BE791090 BM766253 AU118709 BC065512 BM741853 BC044928 BM922808 BX476836
GeneLoc Exon Structure
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Expression
for NSUN5P1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NSUN5P1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTGGGAGGC
About this image
See NSUN5P1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NSUN5P1
SOURCE GeneReport for Unigene cluster: Hs.436034
UniProtKB/Swiss-Prot: NSN5B_HUMAN, Q3KNT7Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for NSUN5P1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NSUN5P1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat NSUN5P1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NSUN5P1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NSUN5P1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NSUN5P1 |
Orthologs
for NSUN5P1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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--
ENSEMBL Gene Tree for NSUN5P1 (if available)
TreeFam Gene Tree for NSUN5P1 (if available) |
Paralogs
for NSUN5P1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for NSUN5P1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NSUN5P1 (75039605 - 75046066 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for NSUN5P1
3 CNVs: 3686 4545 94616 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for NSUN5P1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NSUN5P1 for disorders About GeneDecksing
UniProtKB/Swiss-Prot: NSN5B_HUMAN, Q3KNT7
Note=NSUN5P1 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygousdeletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over betweenhighly homologous low-copy repeat sequences flanking the deleted region
1  disease for NSUN5P1: About MalaCardswilliams-beuren syndrome
Export disorders for NSUN5P1 gene to outside databases
|
Publications
for NSUN5P1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NSUN5P1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with NSUN5P1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of additional transcripts in the Williams-Beuren syndrome critical region. (PubMed id 12073013)1, 2, 3 Merla G....Reymond A. (2002)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Characterization of two novel genes, WBSCR20 and WBSCR22, deleted in Williams-Beuren syndrome. (PubMed id 11978965)1 Doll A. and Grzeschik K.-H. (2001)
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External Searches for NSUN5P1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing NSUN5P1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NSUN5P1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NSUN5P1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NSUN5P1 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for NSUN5P1 gene:
Search GeneIP for patents involving NSUN5P1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NSUN5P1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NSUN5P1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NSUN5P1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NSUN5P1 | | | OriGene Protein Over-expression Lysate for NSUN5P1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NSUN5P1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NSUN5P1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NSUN5P1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NSUN5P1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NSUN5P1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NSUN5P1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NSUN5P1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NSUN5P1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NSUN5P1 |
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 |  |  |  | |
| | | | Search Tocris compounds for NSUN5P1 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NSUN5P1 |
|  |  |  | | | | Search ThermoFisher Antibodies for NSUN5P1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NSUN5P1 |
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