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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NSUN4 Gene

protein-coding   GIFtS: 51
GCID: GC01P046805

NOP2/Sun domain family, member 4

(Previous names: NOL1/NOP2/Sun domain family 4, NOL1/NOP2/Sun domain family,...)
 Explore 2 diseases affiliated with
NSUN4 via our new
 Human Malady Compendium 
Biological research products
for NSUN4
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
NOP2/Sun Domain Family, Member 41 2     RP4-603I14.22
SHTAP1 2     Putative Methyltransferase NSUN42
NOL1/NOP2/Sun Domain Family Member 42 3     Sperm Head And Tail Associated Protein2
MGC229601     EC 2.1.1.-3
NOL1/NOP2/Sun Domain Family 41     EC 2.1.18
NOL1/NOP2/Sun Domain Family, Member 41     EC 2.1.1.298
5-Methylcytosine RRNA Methyltransferase NSUN42     

External Ids:    HGNC: 318021   Entrez Gene: 3873382   Ensembl: ENSG000001174817   UniProtKB: Q96CB93   

Export aliases for NSUN4 gene to outside databases

Previous GC identifers: GC01P046518 GC01P046578 GC01P044939


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: NSUN4_HUMAN, Q96CB9
Function: Involved in mitochondrial ribosome large subunit biogenesis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NSUN4 gene promoter:
         AhR   AP-1   AML1a   NF-kappaB   Arnt   HNF-4alpha1   CP2   MRF-2   NF-kappaB1   TGIF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNSUN4 promoter sequence
   Search SABiosciences Chromatin IP Primers for NSUN4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NSUN4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34   Ensembl cytogenetic band:  1p33   HGNC cytogenetic band: 1p34

NSUN4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NSUN4 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P046805:  view genomic region     (about GC identifiers)

Start:
46,805,849 bp from pter      End:
46,830,824 bp from pter
Size:
24,976 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NSUN4_HUMAN, Q96CB9 (See protein sequence)
Recommended Name: 5-methylcytosine rRNA methyltransferase NSUN4  
Size: 384 amino acids; 43089 Da
Subunit: Heterodimer with MTERF4/MTERFD2
Subcellular location: Mitochondrion
2 PDB 3D structures from and Proteopedia for NSUN4:
4FP9 (3D)        4FZV (3D)    
Secondary accessions: A8K6S6 B3KQ50 B4DHA4 Q5TDF7 Q96AN8 Q9HAJ8
Alternative splicing: 4 isoforms:  Q96CB9-1   Q96CB9-2   Q96CB9-3   Q96CB9-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NSUN4: NX_Q96CB9

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96CB9

  • 4/6 DME Specific Peptides for NSUN4 (Q96CB9) (see all 6)
     CAAPGGK  VYSTCSL  AASLLPVLAL  QFGDLWPSIR 

    NSUN4 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001243056.1  NP_001243057.1  NP_950245.2  

    ENSEMBL proteins: 
     ENSP00000419740   ENSP00000438912   ENSP00000437758  

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    Novus Biologicals NSUN4 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NSUN4

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005762mitochondrial large ribosomal subunit IDA--


    NSUN4 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    NSUN4 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR023267 RCMT
     IPR001678 Fmu/NOL1/Nop2p

    Graphical View of Domain Structure for InterPro Entry Q96CB9

    ProtoNet protein and cluster: Q96CB9

    1 Blocks protein family: IPB001678 Bacterial Sun/eukaryotic nucleolar Nop1/Nop2

    UniProtKB/Swiss-Prot: NSUN4_HUMAN, Q96CB9
    Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: NSUN4_HUMAN, Q96CB9
    Function: Involved in mitochondrial ribosome large subunit biogenesis

    Enzyme Numbers (IUBMB): EC 2.1.1.-1 EC 2.1.12 EC 2.1.1.292

    miRNA
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    miRTarBase miRNAs that target NSUN4:
    hsa-mir-1 (MIRT005275)

    OriGene 3'-UTR Clone: NSUN4
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NSUN4
    8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate NSUN4 (see all 31):
    hsa-miR-137 hsa-miR-188-5p hsa-miR-520d-5p hsa-miR-605 hsa-miR-944 hsa-miR-221 hsa-miR-888* hsa-miR-4275
    SwitchGear 3'UTR luciferase reporter plasmidNSUN4 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NSUN4 (see all 7)
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    OriGene siRNA: NSUN4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NSUN4

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NSUN4

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008168methyltransferase activity IEA--


    NSUN4 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for NSUN4:
     High actin ratio cells 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NSUN4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/240 Interacting proteins for NSUN4 (Q96CB92, 3 ENSP000004197404) via UniProtKB, MINT, STRING, and/or I2D (see all 240)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAGEA11P433642, 3, ENSP000003473584MINT-67878 I2D: score=4 STRING: ENSP00000347358
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    SQSTM1Q135013, ENSP000003744554I2D: score=3 STRING: ENSP00000374455
    KBTBD7Q8WVZ93, ENSP000003687974I2D: score=3 STRING: ENSP00000368797
    EWSR1Q018443, ENSP000003810314I2D: score=2 STRING: ENSP00000381031
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364rRNA processing IEA--


    NSUN4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NSUN4

    1 HMDB Compound for NSUN4    About this table
    CompoundSynonyms CAS #PubMed Ids
    S-Adenosylmethionine(3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine (see all 16)29908-03-0--
    Search CenterWatch for drugs/clinical trials and news about NSUN4 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NSUN4 gene (3 alternative transcripts): 
    NM_001256127.1  NM_001256128.1  NM_199044.3  

    Unigene Cluster for NSUN4:

    NOP2/Sun domain family, member 4
    Hs.163424  [show with all ESTs]
    Unigene Representative Sequence: NR_045789
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000474844 ENST00000474062 ENST00000307089(uc001cpr.1 uc010omc.1 uc009vyf.1 uc009vyg.1 uc001cpt.1 uc001cps.1)
    ENST00000486270 ENST00000469918 ENST00000472157 ENST00000471871 ENST00000498008
    ENST00000495427 ENST00000475281 ENST00000536062 ENST00000537428

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NSUN4
    8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate NSUN4 (see all 31):
    hsa-miR-137 hsa-miR-188-5p hsa-miR-520d-5p hsa-miR-605 hsa-miR-944 hsa-miR-221 hsa-miR-888* hsa-miR-4275
    SwitchGear 3'UTR luciferase reporter plasmidNSUN4 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NSUN4 (see all 7)
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NSUN4
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NSUN4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NSUN4

    Additional cDNA sequence: 

    AK021577.1 AK057420.1 AK291741.1 AK292353.1 AK295003.1 BC014441.1 BX648592.1 NR_045789.1 
    NR_045790.1 NR_045791.1 

    17 DOTS entries:

    DT.97833384  DT.100641559  DT.100858894  DT.456343  DT.95357408  DT.121326401  DT.121326430  DT.100036872 
    DT.121326340  DT.121326524  DT.121326436  DT.95364266  DT.100711789  DT.121326458  DT.121326373  DT.121326516 
    DT.100644566 

    24/336 AceView cDNA sequences (see all 336):

    BQ424895 AL042404 BQ014732 AI565253 CA502993 BF726379 CR620787 AK128066 
    AK021577 AI920966 AI686717 CA395976 CF529182 AA887288 BU171186 U82535 
    CB049339 AI375665 BF913261 NM_199044 AW273419 BI762645 CD722946 BM476102 

    GeneLoc Exon Structure

    5/15 Alternative Splicing Database (ASD) splice patterns (SP) for NSUN4 (see all 15)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c · 6d · 6e · 6f · 6g ^ 7a · 7b ^ 8a ·
    SP1:                                -     -     -     -     -     -     -     -     -     -     -     -                                   -                     
    SP2:                                                                                                  -                                   -                     
    SP3:                                                                                                  -                       -     -     -                     
    SP4:                                -     -     -     -     -     -     -     -     -     -     -     -                                   -           -     -   
    SP5:                                -     -     -     -     -     -     -     -     -     -     -     -                                   -     -     -         

    ExUns: 8b ^ 9a · 9b ^ 10a · 10b
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for NSUN4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NSUN4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGGAGCTTGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See NSUN4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NSUN4

    SOURCE GeneReport for Unigene cluster: Hs.163424
        SABiosciences Custom PCR Arrays for NSUN4
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NSUN4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for NSUN4 gene from 7/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves NSUN41 NOP2/Sun domain family, member 4 64.55(n)
    65.01(a)
      424613  XM_422449.2  XP_422449.2 
    lizard
    (Anolis carolinensis)
    Reptilia NSUN46
    --
    64(a)
    1 ↔ 1
    4(112171438-112182421)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.152582 Transcribed sequence with weak similarity to protein more 72.45(n)    BX719614.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.59912 Transcribed sequence with weak similarity to protein more 74.8(n)    BM037029.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG47491 CG4749 50.04(n)
    39.62(a)
      33293  NM_134729.2  NP_608573.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y39G10AR.211 Protein Y39G10AR.21 48.76(n)
    42.24(a)
      171790  NM_058557.2  NP_490958.1 
    E. coli
    (Escherichia coli)
    Gamma proteobacteria rsmF6
    16S rRNA m(5)C1407 methyltransferase, SAM-dependen...
    12(a)
    1 → many
    Chromosome(1918247-1919686)


    ENSEMBL Gene Tree for NSUN4 (if available)
    TreeFam Gene Tree for NSUN4 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NSUN4 gene
    NOP22  NSUN62  NSUN32  
    1 SIMAP similar gene for NSUN4 using alignment to 2 protein entries:     NSUN4_HUMAN (see all proteins):
    NSUN3

    NSUN4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/613 NCBI SNPs in NSUN4 are shown (see all 613    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1891020201,2
    --46803854(+) GGCAGA/GAGAAT 4 -- us2k10--------
    rs1132571531,2
    C,--46803860(+) AGAATC/TGCTTG 4 -- us2k10--------
    rs1473596231,2
    --46803932(+) CAGAGA/CAAGAC 4 -- us2k10--------
    rs2012293441,2
    --46803950(+) AAAAG-/AAAAAA 4 -- us2k10--------
    rs728851381,2
    C,--46804033(+) TCAACA/GTGATG 4 -- us2k11Minor allele frequency- G:0.00WA 118
    rs728851401,2
    C,--46804064(+) GAAGTG/AAAACT 4 -- us2k11Minor allele frequency- A:0.50WA 2
    rs792173751,2
    C,--46804088(+) GGCTCG/ACACCT 4 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1421045121,2
    C,--46804097(+) TAATC-/AACAGC 4 -- us2k10--------
    rs343172621,2
    C--46804098(+) AATCA-/ACAGCA 4 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1134594901,2
    C,--46804173(+) ACCCCG/ATCTCT 4 -- us2k11Minor allele frequency- A:0.50NA 2

    HapMap Linkage Disequilibrium report for NSUN4 (46805849 - 46830824 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for NSUN4
         2 CNVs: 68521 5491

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    NSUN4 for disorders           About GeneDecksing

    2 diseases for NSUN4:    About MalaCards
    pneumonia    malaria

    Human Genome Epidemiology (HuGE) Navigator: NSUN4 (1 document)

    Export disorders for NSUN4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NSUN4 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with NSUN4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis. (PubMed id 22949673)1, 2 Spahr H.... Hallberg B.M. (2012)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Structure of the essential MTERF4:NSUN4 protein complex reveals how an MTERF protein collaborates to facilitate rRNA modification. (PubMed id 23022348)2 Yakubovskaya E.... Garcia-Diaz M. (2012)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    5. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    6. Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (2010)
    7. A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome. (PubMed id 20186120)1 Richter R....Chrzanowska-Lightowlers Z.M. (2010)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    9. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)1 GratacA^s M....Carracedo A. (2008)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 387338 HGNC: 31802 AceView: FAAHandNSUN4 Ensembl:ENSG00000117481 euGenes: HUgn387338
    ECgene: NSUN4 H-InvDB: NSUN4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NSUN4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NSUN4 gene:
    Search GeneIP for patents involving NSUN4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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