Aliases for NSUN4 Gene
External Ids for NSUN4 Gene
Previous GeneCards Identifiers for NSUN4 Gene
GeneCards Summary for NSUN4 Gene
NSUN4 (NOP2/Sun Domain Family, Member 4) is a Protein Coding gene. GO annotations related to this gene include methyltransferase activity and small ribosomal subunit rRNA binding. An important paralog of this gene is NSUN3.
UniProtKB/Swiss-Prot for NSUN4 Gene
Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.