Aliases for NSMF Gene
External Ids for NSMF Gene
Previous HGNC Symbols for NSMF Gene
Previous GeneCards Identifiers for NSMF Gene
The protein encoded by this gene is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Defects in this gene are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
GeneCards Summary for NSMF Gene
NSMF (NMDA Receptor Synaptonuclear Signaling And Neuronal Migration Factor) is a Protein Coding gene. Diseases associated with NSMF include hypogonadotropic hypogonadism 9 with or without anosmia and normosmic congenital hypogonadotropic hypogonadism. GO annotations related to this gene include calcium-dependent protein binding.
UniProtKB/Swiss-Prot for NSMF Gene
Couples NMDA-sensitive glutamate receptor signaling to the nucleus and triggers long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes. Part of the cAMP response element-binding protein (CREB) shut-off signaling pathway. Stimulates outgrowth of olfactory axons and migration of gonadotropin-releasing hormone (GnRH) and luteinizing-hormone-releasing hormone (LHRH) neuronal cells.