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NSL1 Gene

protein-coding   GIFtS: 56
GCID: GC01M212899

NSL1, MIS12 Kinetochore Complex Component

(Previous names: chromosome 1 open reading frame 48, NSL1, MIND kinetochore...)
(Previous symbol: C1orf48)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
NSL1, MIS12 Kinetochore Complex Component1 2     MIS142
C1orf481 2 3     Kinetochore-Associated Protein NSL1 Homolog2
Chromosome 1 Open Reading Frame 481     NSL1, MIND Kinetochore Complex Component, Homolog2
NSL1, MIND Kinetochore Complex Component, Homolog (S. Cerevisiae)1     

External Ids:    HGNC: 245481   Entrez Gene: 259362   Ensembl: ENSG000001176977   OMIM: 6091745   UniProtKB: Q96IY13   

Export aliases for NSL1 gene to outside databases

Previous GC identifers: GC01M210967 GC01M183576


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NSL1 Gene:
This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are
chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell
division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing
proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge
centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different
isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for NSL1 Gene:
NSL1 (NSL1, MIS12 kinetochore complex component) is a protein-coding gene.

UniProtKB/Swiss-Prot: NSL1_HUMAN, Q96IY1
Function: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and
kinetochore formation during mitosis

Gene Wiki entry for NSL1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NSL1 gene promoter:
         Nkx3-1 v4   Sox5   AML1a   XBP-1   POU2F1   POU2F1a   FOXO4   Cart-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNSL1 promoter sequence
   Search Chromatin IP Primers for NSL1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NSL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q41   Ensembl cytogenetic band:  1q32.3   HGNC cytogenetic band: 1q41

NSL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NSL1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M212899:  view genomic region     (about GC identifiers)

Start:
212,899,495 bp from pter      End:
212,965,139 bp from pter
Size:
65,645 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NSL1_HUMAN, Q96IY1 (See protein sequence)
Recommended Name: Kinetochore-associated protein NSL1 homolog  
Size: 281 amino acids; 32162 Da
Subunit: Component of the MIS12 complex composed of MIS12, DSN1, NSL1/DC8 and PMF1. Interacts with CASC5
Sequence caution: Sequence=AAF86877.1; Type=Frameshift; Positions=41;
Secondary accessions: E7ETD5 Q5SY75 Q9H2M5 Q9NRN8 Q9Y415
Alternative splicing: 2 isoforms:  Q96IY1-1   Q96IY1-2   

Explore the universe of human proteins at neXtProt for NSL1: NX_Q96IY1

Explore proteomics data for NSL1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NSL1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001036014.1  NP_056286.3  

    ENSEMBL proteins: 
     ENSP00000355945   ENSP00000355944   ENSP00000355943   ENSP00000355942   ENSP00000388406  
    Reactome Protein details: Q96IY1

    NSL1 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR013950 Kinetochore_Mis14

    Graphical View of Domain Structure for InterPro Entry Q96IY1

    ProtoNet protein and cluster: Q96IY1

    1 Blocks protein domain: IPB002052 N-6 Adenine-specific DNA methylase


    Find genes that share domains with NSL1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NSL1_HUMAN, Q96IY1
    Function: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and
    kinetochore formation during mitosis

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI15502821
         
    Find genes that share ontologies with NSL1           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NSL1
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NSL1

    miRNA
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    miRTarBase miRNAs that target NSL1:
    hsa-mir-26b-5p (MIRT030278), hsa-mir-421 (MIRT016100)

    Block miRNA regulation of human, mouse, rat NSL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NSL1 (see all 47):
    hsa-miR-579 hsa-miR-323-3p hsa-miR-607 hsa-miR-642a hsa-miR-578 hsa-miR-550a* hsa-miR-3667-5p hsa-miR-3161
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NSL1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NSL1_HUMAN, Q96IY1: Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol4
    plasma membrane4
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000444MIS12/MIND type complex IDA16585270
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm ----
    GO:0005829cytosol TAS--
    GO:0005886plasma membrane ----

    Find genes that share ontologies with NSL1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for NSL1 About    
    See pathways by source

    SuperPathContained pathways About
    1Mitotic Metaphase and Anaphase
    Mitotic Anaphase0.94
    Mitotic Metaphase and Anaphase0.93
    Separation of Sister Chromatids0.94
    2Cell Cycle, Mitotic
    Cell Cycle, Mitotic0.90
    M Phase0.62
    Cell Cycle0.90
    3Mitotic Prometaphase
    Mitotic Prometaphase0.92
    Resolution of Sister Chromatid Cohesion0.92


    Find genes that share SuperPaths with NSL1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3 Reactome Pathways for NSL1
        Resolution of Sister Chromatid Cohesion
    Mitotic Prometaphase
    Separation of Sister Chromatids


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NSL1
    Interactions:

        Search GeneGlobe Interaction Network for NSL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NSL1 (Q96IY13 ENSP000003559444) via UniProtKB, MINT, STRING, and/or I2D (see all 86)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MIS12Q9H0813, ENSP000003705574I2D: score=4 STRING: ENSP00000370557
    DSN1Q9H4103, ENSP000003628504I2D: score=3 STRING: ENSP00000362850
    ZWINTO952293, ENSP000003630554I2D: score=2 STRING: ENSP00000363055
    BUB1O436833, ENSP000003025304I2D: score=2 STRING: ENSP00000302530
    CBX5P459733, ENSP000002098754I2D: score=4 STRING: ENSP00000209875
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0007059chromosome segregation IEA--
    GO:0007067mitosis IEA--

    Find genes that share ontologies with NSL1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NSL1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NSL1 gene (2 alternative transcripts): 
    NM_001042549.1  NM_015471.3  

    Unigene Cluster for NSL1:

    NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
    Hs.497692  [show with all ESTs]
    Unigene Representative Sequence: NM_001042549
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000366978 ENST00000366977(uc001hjm.3 uc001hjn.3 uc010pti.2)
    ENST00000366976 ENST00000473995 ENST00000487995 ENST00000366975 ENST00000422588

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate NSL1 (see all 47):
    hsa-miR-579 hsa-miR-323-3p hsa-miR-607 hsa-miR-642a hsa-miR-578 hsa-miR-550a* hsa-miR-3667-5p hsa-miR-3161
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Predesigned siRNA for gene silencing in human, mouse, rat NSL1
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): NSL1 (NM_015471)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NSL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NSL1
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for NSL1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NSL1
      QuantiTect SYBR Green Assays in human, mouse, rat NSL1
      QuantiFast Probe-based Assays in human, mouse, rat NSL1

    Additional mRNA sequence: 

    AF201941.1 AF255793.1 AK092359.1 AK124596.1 AK222996.1 AK223260.1 AK303250.1 AK313730.1 
    AL050084.1 BC007067.1 BC036048.1 

    19 DOTS entries:

    DT.454526  DT.92444149  DT.92444143  DT.307964  DT.101979802  DT.92444151  DT.121392590  DT.75125990 
    DT.75162347  DT.95103541  DT.100647874  DT.75101377  DT.92444142  DT.92444144  DT.95084242  DT.95084243 
    DT.99967484  DT.40222289  DT.92444152 

    Selected AceView cDNA sequences (see all 150):

    BE738948 BG493146 BF056313 BE501789 BQ023978 BM786567 AI203449 AI648537 
    BX097965 AA856553 BU077762 BQ068485 BU077551 AA746075 AI468606 BE407911 
    AW958294 CA310833 BG613883 BG503949 BG613808 AA843539 BF665517 F36078 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NSL1 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e
    SP1:              -           -           -                                                   
    SP2:              -           -           -           -                                       
    SP3:              -           -           -           -     -                                 
    SP4:              -     -     -           -           -                                       
    SP5:              -           -           -     -     -                                       


    ECgene alternative splicing isoforms for NSL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NSL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGCCAAAAA
    NSL1 Expression
    About this image

    NSL1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NSL1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.497692
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NSL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for NSL1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nsl11 , 5 NSL1, MIND kinetochore complex component, homolog (S. more1, 5 75.36(n)1
    67.5(a)1
      1 (96.28 cM)5
    3813181  NM_198654.31  NP_941056.31 
     1910630125 
    chicken
    (Gallus gallus)
    Aves NSL11 NSL1, MIND kinetochore complex component, homolog (S. more 60.44(n)
    47.47(a)
      421367  NM_001044646.1  NP_001038111.1 
    lizard
    (Anolis carolinensis)
    Reptilia NSL16
    NSL1, MIS12 kinetochore complex component
    36(a)
    1 ↔ 1
    1(238672110-238696319)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia nsl11 NSL1, MIS12 kinetochore complex component 54.15(n)
    44.08(a)
      100380008  XM_002934685.2  XP_002934731.2 
    zebrafish
    (Danio rerio)
    Actinopterygii nsl11 NSL1, MIND kinetochore complex component, homolog (S. more 48.58(n)
    35.64(a)
      562522  NM_001025521.2  NP_001020692.1 


    ENSEMBL Gene Tree for NSL1 (if available)
    TreeFam Gene Tree for NSL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NSL1 gene
    1 SIMAP similar gene for NSL1 using alignment to 4 protein entries:     NSL1_HUMAN (see all proteins):
    C1orf48

    Find genes that share paralogs with NSL1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NSL1 (see all 1346)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1918204601,2
    C--212898998(+) AACCAC/GAGACC 2 -- ds50010--------
    rs1428426521,2
    --212899004(+) AGACCC/TTTGTT 2 -- ds50010--------
    rs1465147841,2
    --212899013(+) TTCACA/TTGTTT 2 -- ds50010--------
    rs2003257821,2
    C--212899051(+) TCCTA-/GAACCCT 2 -- ds50010--------
    rs24927851,2
    C--212899182(+) TTTTTT/AAAAAA 2 -- ds50011Minor allele frequency- A:0.00WA 2
    rs344506501,2
    C--212899183(+) TTTTAA/TAAAAA 2 -- ds50010--------
    rs788169181,2
    C,F--212899299(+) CAACAG/AGATAT 2 -- ds50011Minor allele frequency- A:0.10WA 118
    rs127509281,2
    C--212899461(+) GCAGCA/CCGGTA 2 -- ds50010--------
    rs730799001,2
    C--212899514(+) TATTCG/TATTTT 2 -- ut312Minor allele frequency- T:0.04WA 120
    rs120477971,2
    C--212899531(+) TGAAAA/GATGCA 2 -- ut31 ese30--------

    HapMap Linkage Disequilibrium report for NSL1 (212899495 - 212965139 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for NSL1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv159271CNV Loss16902084
    dgv179e1CNV Complex17122850

    Human Gene Mutation Database (HGMD): NSL1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NSL1
    DNA2.0 Custom Variant and Variant Library Synthesis for NSL1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609174    OMIM disorders: --


    Find genes that share disorders with NSL1           About GenesLikeMe

    Genetic Association Database (GAD): NSL1
    Human Genome Epidemiology (HuGE) Navigator: NSL1 (1 document)

    Export disorders for NSL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NSL1 gene, integrated from 10 sources (see all 29):
    (articles sorted by number of sources associating them with NSL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The MIS12 complex is a protein interaction hub for outer kinetochore assembly. (PubMed id 20819937)1, 3 Petrovic A....Musacchio A. (J. Cell Biol. 2010)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1. (PubMed id 17981135)1, 2 Kiyomitsu T.... Yanagida M. (Dev. Cell 2007)
    4. The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. (PubMed id 16585270)1, 2 Kline S.L.... Desai A. (J. Cell Biol. 2006)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    6. A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. (PubMed id 15502821)1, 2 Obuse C....Yanagida M. (Nat. Cell Biol. 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Plk1 phosphorylates Sgt1 at the kinetochores to promote timely kinetochore-microtubule attachment. (PubMed id 22869522)1 Liu X.S....Liu X. (Mol. Cell. Biol. 2012)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25936 HGNC: 24548 AceView: DC8 Ensembl:ENSG00000117697 euGenes: HUgn25936
    ECgene: NSL1 H-InvDB: NSL1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NSL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NSL1 gene:
    Search GeneIP for patents involving NSL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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