Aliases for NSF Gene
External Ids for NSF Gene
GeneCards Summary for NSF Gene
NSF (N-Ethylmaleimide-Sensitive Factor) is a Protein Coding gene. Diseases associated with NSF include neuronal intranuclear inclusion disease and botulism. Among its related pathways are Cytoskeletal Signaling and Vasopressin-regulated water reabsorption. GO annotations related to this gene include protein complex binding and syntaxin binding.
UniProtKB/Swiss-Prot for NSF Gene
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling (By similarity).