Aliases for NRROS Gene
External Ids for NRROS Gene
Previous HGNC Symbols for NRROS Gene
Previous GeneCards Identifiers for NRROS Gene
GeneCards Summary for NRROS Gene
NRROS (Negative Regulator Of Reactive Oxygen Species) is a Protein Coding gene. An important paralog of this gene is LRRC32.
UniProtKB/Swiss-Prot for NRROS Gene
Negative regulator of reactive oxygen species (ROS) that limits ROS production by phagocytes during inflammatory response, thereby playing a role during host defense. Acts via direct interaction with CYBB/NOX2 monomer that impairs interaction between CYBB/NOX2 and CYBA/p22-phox and formation of a stable NOX2 complex (By similarity). May play a critical role in desensitizing TLR signaling through inhibition of Toll-like receptor-mediated NF-kappa-B activation and cytokine production.