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NRN1 Gene

protein-coding   GIFtS: 54
GCID: GC06M005943

Neuritin 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Neuritin 11 2
NRN2 3 5
dJ380B8.22
neuritin2

External Ids:    HGNC: 179721   Entrez Gene: 512992   Ensembl: ENSG000001247857   OMIM: 6074095   UniProtKB: Q9NPD73   

Export aliases for NRN1 gene to outside databases

Previous GC identifers: GC06M005983 GC06M005873


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NRN1 Gene:
This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the
developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of
this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage
signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite
outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded
protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript
variants. (provided by RefSeq, Jul 2013)

GeneCards Summary for NRN1 Gene:
NRN1 (neuritin 1) is a protein-coding gene. Diseases associated with NRN1 include astrocytoma, and spinal cord injury. An important paralog of this gene is NRN1L.

UniProtKB/Swiss-Prot: NRN1_HUMAN, Q9NPD7
Function: Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and
cortical cells (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NRN1 gene promoter:
         FOXJ2 (long isoform)   Cart-1   MyoD   CUTL1   FOXJ2   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNRN1 promoter sequence
   Search Chromatin IP Primers for NRN1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NRN1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p25.1   Ensembl cytogenetic band:  6p25.1   HGNC cytogenetic band: 6p25.1

NRN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NRN1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M005943:  view genomic region     (about GC identifiers)

Start:
5,998,232 bp from pter      End:
6,007,633 bp from pter
Size:
9,402 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NRN1_HUMAN, Q9NPD7 (See protein sequence)
Recommended Name: Neuritin precursor  
Size: 142 amino acids; 15333 Da
Subunit: Component of the outer core of AMPAR complex. AMPAR complex consists of an inner core made of 4
pore-forming GluA/GRIA proteins (GRIA1, GRIA2, GRIA3 and GRIA4) and 4 major auxiliary subunits arranged in a
twofold symmetry. One of the two pairs of distinct binding sites is occupied either by CNIH2, CNIH3 or CACNG2,
CACNG3. The other harbors CACNG2, CACNG3, CACNG4, CACNG8 or GSG1L. This inner core of AMPAR complex is
complemented by outer core constituents binding directly to the GluA/GRIA proteins at sites distinct from the
interaction sites of the inner core constituents. Outer core constituents include at least PRRT1, PRRT2,
CKAMP44/SHISA9, FRRS1L and NRN1. The proteins of the inner and outer core serve as a platform for other, more
peripherally associated AMPAR constituents. Alone or in combination, these auxiliary subunits control the gating
and pharmacology of the AMPAR complex and profoundly impact their biogenesis and protein processing (By
similarity)
Secondary accessions: B2RA93 Q7Z4Y1

Explore the universe of human proteins at neXtProt for NRN1: NX_Q9NPD7

Explore proteomics data for NRN1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NRN1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001265639.1  NP_001265640.1  NP_057672.1  

    ENSEMBL proteins: 
     ENSP00000244766  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026144 Neuritin_fam

    Graphical View of Domain Structure for InterPro Entry Q9NPD7

    ProtoNet protein and cluster: Q9NPD7

    UniProtKB/Swiss-Prot: NRN1_HUMAN, Q9NPD7
    Similarity: Belongs to the neuritin family


    NRN1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NRN1_HUMAN, Q9NPD7
    Function: Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and
    cortical cells (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for NRN1:

     Elongated cells 

         5 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Nrn1):
     behavior/neurological  cellular  growth/size/body  nervous system  no phenotypic analysis 

    NRN1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Nrn1tm1.2Ndiv for NRN1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NRN1
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NRN1

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    miRTarBase miRNAs that target NRN1:
    hsa-mir-28-5p (MIRT049996), hsa-mir-26b-5p (MIRT028913), hsa-mir-25-3p (MIRT050310)

    Block miRNA regulation of human, mouse, rat NRN1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NRN1 (see all 42):
    hsa-miR-374a hsa-miR-449a hsa-miR-647 hsa-miR-4324 hsa-miR-34c-5p hsa-miR-449b hsa-miR-186* hsa-miR-374b
    SwitchGear 3'UTR luciferase reporter plasmidNRN1 3' UTR sequence
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRN1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NRN1_HUMAN, Q9NPD7: Cell membrane; Lipid-anchor, GPI-anchor (Potential). Cell junction, synapse (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular2
    cytoskeleton1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030054cell junction IEA--
    GO:0031225anchored component of membrane IEA--
    GO:0032281alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex IEA--
    GO:0045202synapse IEA--

    NRN1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NRN1
    Interactions:

        Search GeneGlobe Interaction Network for NRN1

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007399nervous system development IEA--

    NRN1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NRN1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for NRN1 gene (3 alternative transcripts): 
    NM_001278710.1  NM_001278711.1  NM_016588.2  

    Unigene Cluster for NRN1:

    Neuritin 1
    Hs.103291  [show with all ESTs]
    Unigene Representative Sequence: BC042019
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000244766(uc021ykx.1 uc003mwu.3) ENST00000495850
    miRNA
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    Block miRNA regulation of human, mouse, rat NRN1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NRN1 (see all 42):
    hsa-miR-374a hsa-miR-449a hsa-miR-647 hsa-miR-4324 hsa-miR-34c-5p hsa-miR-449b hsa-miR-186* hsa-miR-374b
    SwitchGear 3'UTR luciferase reporter plasmidNRN1 3' UTR sequence
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NRN1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NRN1
      QuantiTect SYBR Green Assays in human, mouse, rat NRN1
      QuantiFast Probe-based Assays in human, mouse, rat NRN1

    Additional mRNA sequence: 

    AF114833.1 AF136631.1 AJ420483.1 AK093824.1 AK314095.1 BC002683.2 BC042019.1 

    10 DOTS entries:

    DT.445436  DT.100792356  DT.100792349  DT.100792353  DT.121355089  DT.100029054  DT.100792345  DT.91928122 
    DT.97762304  DT.95175068 

    Selected AceView cDNA sequences (see all 200):

    BE296947 CD107153 T08179 CR610397 CD519184 CR610504 AA551666 CD109891 
    BQ720570 BQ576342 CR624108 BU173962 BU163971 CR620311 BX279990 W74094 
    BM974374 BG057912 AI190645 BU150419 CR614740 AK093824 BU177968 BQ005144 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for NRN1    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c
    SP1:        -           -     -     -     -                           
    SP2:                    -     -     -     -                           
    SP3:                          -           -                           
    SP4:                                      -                           
    SP5:                                                                  


    ECgene alternative splicing isoforms for NRN1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NRN1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGCTATGGT
    NRN1 Expression
    About this image


    NRN1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Amygdala
     
     Eye (Sensory Organs)
             Corneal Stroma
     
     Ovary (Reproductive System)
             Pre-Granulosa Cells Primordial Follicle
     
     Epidermis (Integumentary System)
             Detroit 551
    NRN1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NRN1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.103291
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRN1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for NRN1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nrn11 , 5 neuritin 11, 5 96.71(n)1
    97.18(a)1
      13 (14.44 cM)5
    684041  NM_153529.21  NP_705757.11 
     367256255 
    chicken
    (Gallus gallus)
    Aves NRN11 neuritin 1 81.29(n)
    80.58(a)
      420873  NM_001198731.1  NP_001185660.1 
    lizard
    (Anolis carolinensis)
    Reptilia NRN16
    neuritin 1
    63(a)
    1 ↔ 1
    GL343421.1(567039-604764)
    African clawed frog
    (Xenopus laevis)
    Amphibia nrn1-A2 neuritin 1/candidate plasticity gene 15 80.25(n)    AF378092.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.292312 Transcribed sequence with weak similarity to protein more 73.96(n)    CK360748.1 


    ENSEMBL Gene Tree for NRN1 (if available)
    TreeFam Gene Tree for NRN1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NRN1 gene
    NRN1L2  
    1 SIMAP similar gene for NRN1 using alignment to 1 protein entry:     NRN1_HUMAN:
    NRN1L

    NRN1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for NRN1
    PGOHUM00000247542


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NRN1 (see all 267)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs121538591,2
    C,H--5998231(+) CCCCCA/TTTTCA 1 -- ds50014Minor allele frequency- T:0.00NS EA 416
    rs709759391,2
    C--5998334(+) TTTTTT/-AAAAT 1 -- ut311Minor allele frequency- -:0.00NA 2
    rs2004576711,2
    --5998334(+) TCTCT-/CTTTTT 1 -- ut310--------
    rs38343161,2
    C--5998335(-) AAAAA-/AGAGAG 1 -- ut310--------
    rs10527271,2
    C--5998392(-) TTAATC/TTAAAA 1 -- ut310--------
    rs1853845921,2
    --5998510(+) GACGGA/TTGCAT 1 -- ut310--------
    rs1461480771,2
    C--5998619(+) TCTCCC/TTCCTA 1 -- ut310--------
    rs1995485331,2
    --5998894(+) CCAAC-/AAAAAA 1 -- ut310--------
    rs2005267861,2
    --5999239(+) GCTGCC/TGAGAG 2 S syn10--------
    rs1401634121,2
    C,F--5999254(+) ACCAGG/AAGCAC 2 /L syn12Minor allele frequency- A:0.01NA EU 4423

    HapMap Linkage Disequilibrium report for NRN1 (5998232 - 6007633 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for NRN1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv436891CNV Insertion17901297
    nsv483131CNV Loss15286789

    Human Gene Mutation Database (HGMD): NRN1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NRN1
    DNA2.0 Custom Variant and Variant Library Synthesis for NRN1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607409    OMIM disorders: --

    6 diseases for NRN1:    
    About MalaCards
    astrocytoma    spinal cord injury    neuronitis    hypoxia
    schizophrenia    endotheliitis


    NRN1 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for NRN1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 2 16723126 (1)

    Genetic Association Database (GAD): NRN1
    Human Genome Epidemiology (HuGE) Navigator: NRN1 (1 document)

    Export disorders for NRN1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NRN1 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with NRN1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Neuritin: a gene induced by neural activity and neurotrophins that promotes neuritogenesis. (PubMed id 9122250)1, 2, 3, 9 Naeve G.S....Theill L.E. (Proc. Natl. Acad. Sci. U.S.A. 1997)
    2. Impact of Neuritin 1 (NRN1) polymorphisms on fluid intelligence in schizophrenia. (PubMed id 19569075)1, 4, 9 Chandler D....Jablensky A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    6. Characterization of the expression of the hypoxia-induced genes neuritin, TXNIP and IGFBP3 in cancer. (PubMed id 16723126)1, 9 Le Jan S....Germain S. (FEBS Lett. 2006)
    7. cpg15 and cpg15-2 constitute a family of activity-regulated ligands expressed differentially in the nervous system to promote neurite growth and neuronal survival. (PubMed id 18265009)1, 9 Fujino T....Nedivi E. (J. Comp. Neurol. 2008)
    8. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    9. Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits. (PubMed id 21652774)1 Akten B....Sahin M. (Proc. Natl. Acad. Sci. U.S.A. 2011)
    10. Neuritin expression and its relation with proliferation, apoptosis, and angiogenesis in human astrocytoma. (PubMed id 20405246)1 Zhang L....Zhen H.N. (Med. Oncol. 2011)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51299 HGNC: 17972 AceView: NRN1 Ensembl:ENSG00000124785 euGenes: HUgn51299
    ECgene: NRN1 H-InvDB: NRN1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NRN1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for NRN1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NRN1 gene:
    Search GeneIP for patents involving NRN1

    GeneCards and IP:
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