Aliases for NRL Gene
External Ids for NRL Gene
This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. [provided by RefSeq, Jul 2008]
GeneCards Summary for NRL Gene
NRL (Neural Retina Leucine Zipper) is a Protein Coding gene. Diseases associated with NRL include retinal degeneration autosomal recessive clumped pigment type and retinitis pigmentosa 27. Among its related pathways are Tacrolimus/Cyclosporine Pathway, Pharmacodynamics. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and leucine zipper domain binding. An important paralog of this gene is MAFA.
UniProtKB/Swiss-Prot for NRL Gene
Transcription factor which regulates the expression of several rod-specific genes, in cluding RHO and PDE6B.