Aliases for NRK Gene
External Ids for NRK Gene
Previous GeneCards Identifiers for NRK Gene
The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.[provided by RefSeq, Jun 2010]
GeneCards Summary for NRK Gene
NRK (Nik Related Kinase) is a Protein Coding gene. Diseases associated with NRK include Hypermobility Syndrome and Sotos Syndrome 1. Among its related pathways are TNF signaling (REACTOME) and NAD metabolism. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is TNIK.
UniProtKB/Swiss-Prot for NRK Gene
May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway (By similarity).