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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NRK Gene

protein-coding   GIFtS: 52
GCID: GC0XP105067

Nik related kinase
 Explore 4 diseases affiliated with
NRK via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NRK    

Aliases
for NRK gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Nik Related Kinase1 2
EC 2.7.11.13 8
NESK2 5
DKFZp686A171091
Nik-Related Protein Kinase2
EC 2.7.118

External Ids:    HGNC: 253911   Entrez Gene: 2034472   Ensembl: ENSG000001235727   OMIM: 3007915   UniProtKB: Q7Z2Y53   

Export aliases for NRK gene to outside databases

Previous GC identifers: GC0XP103839 GC0XP104872 GC0XP094691


Summaries
for NRK gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for NRK:
The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be
involved in the induction of actin polymerization in late embryogenesis.(provided by RefSeq, Jun 2010)

UniProtKB/Swiss-Prot: NRK_HUMAN, Q7Z2Y5
Function: May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of
embryogenesis. Involved in the TNF-alpha-induced signaling pathway (By similarity)

Gene Wiki entry for NRK


Genomic Views
for NRK gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_011651.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NRK gene promoter:
         AP-1   ATF-2   CREB   AREB6   MZF-1   deltaCREB   FOXO4   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NRK promoter sequence
   Search SABiosciences Chromatin IP Primers for NRK

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NRK


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.3   Ensembl cytogenetic band:  Xq22.3   HGNC cytogenetic band: Xq22.3

NRK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NRK gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP105067:  view genomic region     (about GC identifiers)

Start:
 105,066,536 bp from pter      End:
 105,202,602 bp from pter
Size:
 136,067 bases      Orientation:
 plus strand

Proteins
for NRK gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NRK_HUMAN, Q7Z2Y5 (See protein sequence)
Recommended Name: Nik-related protein kinase  
Size: 1582 amino acids; 178479 Da
Secondary accessions: Q32ND6 Q5H9K2 Q6ZMP2
Alternative splicing: 3 isoforms:  Q7Z2Y5-1   Q7Z2Y5-2   Q7Z2Y5-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NRK: NX_Q7Z2Y5

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q7Z2Y5

    • 4/6 DME Specific Peptides for NRK (Q7Z2Y5) (see all 6)
     WMAPEVI  GTPYWMAPE  LNLLITISG  FIGTPYWMAPEV 

    NRK Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_940867.2  
    ENSEMBL proteins: 
     ENSP00000434830   ENSP00000438378   ENSP00000438785   ENSP00000438148  

    Human Recombinant Protein Products: 
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    Uscn Proteins for NRK


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    Uscn ELISAs and CLIAs for NRK

    Protein Domains /
    Families
    for NRK gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NRK for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR017441 Protein_kinase_ATP_BS
     IPR002290 Ser/Thr_dual-sp_kinase_dom
     IPR001180 Citron
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS

    Graphical View of Domain Structure for InterPro Entry Q7Z2Y5

    ProtoNet protein and cluster: Q7Z2Y5

    1 Blocks protein family: IPB001180 Citron-like

    UniProtKB/Swiss-Prot: NRK_HUMAN, Q7Z2Y5
    Similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily
    Similarity: Contains 1 CNH domain
    Similarity: Contains 1 protein kinase domain


    Function
    for NRK gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NRK_HUMAN, Q7Z2Y5
    Function: May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of
    embryogenesis. Involved in the TNF-alpha-induced signaling pathway (By similarity)
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

    Enzyme Numbers (IUBMB): EC 2.7.11.11 2 EC 2.7.112

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NRK
    8/116 QIAGEN miScript miRNA Assays for microRNAs that regulate NRK (see all 116):
    hsa-miR-323-3p hsa-miR-26a-2* hsa-miR-607 hsa-miR-1258 hsa-miR-128 hsa-miR-374a hsa-miR-30d hsa-miR-550a*
    SwitchGear 3'UTR luciferase reporter plasmid: NRK 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NRK (see all 4)
    OriGene shRNA RFP: NRK
    OriGene siRNA: NRK
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NRK

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for NRK

    Clone
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    Search LifeMap BioReagents cell lines for NRK

    In Situ Assay
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0005083small GTPase regulator activity IEA--
    GO:0005524ATP binding IEA--
    GO:0016301kinase activity ----


    NRK for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for NRK:
     Decreased CYP1A1 activity afte  Decreased focal adhesion (FA)   Upregulation of Wnt/beta-caten 

    Animal Models:
         Mouse knock-out Nrktm1Mkom for NRK
         3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Nrk):
     embryogenesis  mortality/aging  reproductive system 

    NRK for phenotypes           About GeneDecksing


    Pathways & Interactions
    for NRK gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1TNF receptor signaling pathway
    		TNF receptor signaling pathway1.00


    1 BioSystems Pathway for NRK 
        TNF receptor signaling pathway


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NRK

    1 Interacting protein for NRK (Q7Z2Y53) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CFL1P235283I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007256activation of JNKK activity ----
    GO:0007567parturition ----
    GO:0008285negative regulation of cell proliferation ----
    GO:0060721regulation of spongiotrophoblast cell proliferation ----


    NRK for ontologies           About GeneDecksing



    Drugs & Compounds
    for NRK gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NRK
    Search CenterWatch for drugs/clinical trials and news about NRK 

    Transcripts
    for NRK gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NRK gene: 
    NM_198465.2  

    Unigene Cluster for NRK:

    Nik related kinase
    Hs.209527  [show with all ESTs]
    Unigene Representative Sequence: BX538345
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000243300(uc004emd.3 uc011msi.2) ENST00000428173(uc010npc.1)
    ENST00000536164 ENST00000540278

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NRK
    8/116 QIAGEN miScript miRNA Assays for microRNAs that regulate NRK (see all 116):
    hsa-miR-323-3p hsa-miR-26a-2* hsa-miR-607 hsa-miR-1258 hsa-miR-128 hsa-miR-374a hsa-miR-30d hsa-miR-550a*
    SwitchGear 3'UTR luciferase reporter plasmid: NRK 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NRK (see all 4)
    OriGene shRNA RFP: NRK
    OriGene siRNA: NRK
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): NRK (NM_017719)
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NRK

    Additional cDNA sequence: 

    AK131549.1 AK293500.1 AK300377.1 BC108702.1 BX538345.1 

    5 DOTS entries:

    DT.114556  DT.97777096  DT.121320158  DT.121320173  DT.121320168 

    24/74 AceView cDNA sequences (see all 74):

    AI803353 BQ771725 AW594026 AA992147 AI473381 AW102594 BM683045 AI280290 
    AW664774 AI016565 AK131549 BX108491 BQ774422 AI209073 BQ181298 AI016408 
    AI358516 AA779246 AA742454 AI917597 BF223049 BG571017 NM_198465 BX538345 

    GeneLoc Exon Structure


    Expression
    for NRK gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NRK expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NRK expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    10/12 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 12) 
    Tissue Anatomical Compartment CellCategory (developmental path)
    HeartMyocardiumCardiac FibroblastsEpicardium
    LimbForelimb MyotomeLimb Muscle Progenitor CellsSkeletal Muscle
    LimbStylopodMesenchymal Condensate CellsBone, Cartilage
    LimbZeugopodMesenchymal Condensate CellsBone, Cartilage
    Skeletal MuscleHyoid Arch MusclesMyoblastsSkeletal Muscle
    Skeletal MuscleMandibular Arch MusclesMyoblastsSkeletal Muscle
    BoneZeugopod Long BoneBone
    HeartHeart TubeHeart
    LimbAutopodLimb
    LimbStylopodLimb
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    PureStem™ epithelial progenitor E164 (Embryonic Progenitor Cell)Intermediate Mesoderm, Kidney
    Primordial germ cell-like cells (Reconstitution of mo...)

    See NRK Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NRK

    SOURCE GeneReport for Unigene cluster: Hs.209527
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    In Situ
    Assay Products:     
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    Orthologs
    for NRK gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for NRK gene from 7/24 species (see all 24)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves STK256
    Q5F375_CHICK6
    (see all 3)    		 serine/threonine kinase 24 (STE20 homolog, yeast)
    (see all 3)    		 27(a)
    27(a)
    (see all 3)    		 possible ortholog
    possible ortholog
    (see all 3)    		 9(6120772-6137529)
    1(149053927-149110077)
    lizard
    (Anolis carolinensis)    		 Reptilia STK246
    STK256
    (see all 3)    		 --
    		 30(a)
    28(a)
    (see all 3)    		 possible ortholog
    possible ortholog
    (see all 3)    		 3(98459893-98480944)
    3(30415056-30434293)
    zebrafish
    (Danio rerio)    		 Actinopterygii stk25a6
    zgc:1752886
    (see all 5)    		 zgc:175288
    (see all 5)    		 28(a)
    27(a)
    (see all 5)    		 possible ortholog
    possible ortholog
    (see all 5)    		 6(26749822-26765930)
    21(41826082-41863332)
    fruit fly
    (Drosophila melanogaster)    		 Insecta GckIII6
    		 Germinal centre kinase III
    		 19(a)
    		 possible ortholog
    		 3R(12911256-12913710)
    worm
    (Caenorhabditis elegans)    		 Secernentea gck-16
    		 Germinal Center Kinase family member (gck-1)
    		 19(a)
    		 possible ortholog
    		 V(8947777-8955870)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT3G152206
    ATMAP4K ALPHA16
    		 map 4 kinase alpha1
    		 21(a)
    20(a)
    		 possible ortholog
    possible ortholog
    		 3(5126597-5132306)
    1(19813804-19819564)
    rice
    (Oryza sativa)    		 Liliopsida --
    		 STE_PAK_Ste20_MST_like.1 - STE kinases include hom...
    		 20(a)
    		 possible ortholog
    		 7(19257731-19267291)


    ENSEMBL Gene Tree for NRK (if available)
    TreeFam Gene Tree for NRK (if available) 

    Paralogs
    for NRK gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NRK gene
    TAOK22  MAP4K52  TAOK32  TNIK2  MAP4K22  MAP4K12  MAP4K32  MAP4K42  
    TAOK12  STK102  MINK12  SLK2  
    18/21 SIMAP similar genes for NRK using alignment to 5 protein entries:     NRK_HUMAN (see all proteins) (see all similar genes):
    PAK4    MYO3A    STK24    MST4    STK4    MARK4
    STK3    MAP4K4    MAP3K2    DKFZp686J1430    NEK6    RPS6KA2
    STK11    STK25    MAP2K5    TNIK    CDK4    MINK1

    NRK for paralogs           About GeneDecksing



    Genomic Variants
    for NRK gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1245 NCBI SNPs in NRK are shown (see all 1245)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr X posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1885847941,2
    		--105064605(+) ACGGGA/GCATTT 1 -- us2k10--------
    rs2016831171,2
    		--105064765(+) AATGT-/GTATGT 1 -- us2k10--------
    rs1811588301,2
    		--105065038(+) TTTGGG/TGGAAG 1 -- us2k10--------
    rs169848451,2
    		C,F,H,--105065101(+) GAGACC/GCGGTT 1 -- us2k17Minor allele frequency- G:0.01NA NS EA 556
    rs1482379111,2
    		--105065281(+) GTGGGA/GAGAAT 1 -- us2k10--------
    rs1866174341,2
    		--105065336(+) AAAAAG/TAAAGA 1 -- us2k10--------
    rs1125936201,2
    		C,--105065381(+) CCGACT/CCCGGA 1 -- us2k12Minor allele frequency- C:0.00NA 2
    rs1914162011,2
    		--105065898(+) CCAGCA/GGCTCT 1 -- us2k10--------
    rs9687521,2
    		C,F,A,H,--105066585(-) GCGTCA/CGTCCT 1 -- ut51 ese314Minor allele frequency- C:0.22MN NS EA NA CSA 1369
    rs1390872481,2
    		--105066599(+) GGCTCC/GTCTCT 1 -- ut510--------

    HapMap Linkage Disequilibrium report for NRK (105066536 - 105202602 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 9 variations for NRK
         1 CNV: 8310
         8 Indels: 96878 103269 96881 96879 96880 83663 47760 42050
    Locus Specific Mutation Databases (LSDB): NRK

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NRK
    DNA2.0 Custom Variant and Variant Library Synthesis for NRK

    Disorders / Diseases
    for NRK gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NRK for disorders           About GeneDecksing

    OMIM gene information: 300791    OMIM disorders: --

    4 diseases for NRK:    About MalaCards
    hyperinsulinemic hypoglycemia    hypermobility syndrome    sotos syndrome    hypoglycemia

    2 diseases from the University of Copenhagen DISEASES database for NRK:
    Hypermobility syndrome     Sotos syndrome

    Export disorders for NRK gene to outside databases

    Publications
    for NRK gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NRK gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with NRK)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    5. Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)2 Greenman C.... Stratton M.R. (2007)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    7. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
    8. From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
    9. Cofilin phosphorylation and actin polymerization by NRK/NESK, a member of the germinal center kinase family. (PubMed id 12837278)1 Nakano K.... Kitamura N. (2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for NRK gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing NRK gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 203447 HGNC: 25391 AceView: NRK Ensembl:ENSG00000123572 euGenes: HUgn203447
    ECgene: NRK H-InvDB: NRK

    Other Databases showing NRK gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing NRK gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NRK Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NRK gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NRK gene:
    Search GeneIP for patents involving NRK

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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