Aliases for NRK Gene
External Ids for NRK Gene
Previous GeneCards Identifiers for NRK Gene
The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.[provided by RefSeq, Jun 2010]
GeneCards Summary for NRK Gene
NRK (Nik Related Kinase) is a Protein Coding gene. Diseases associated with NRK include Sotos Syndrome 1. Among its related pathways are TNF signaling (REACTOME). GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is TNIK.
UniProtKB/Swiss-Prot for NRK Gene
May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway (By similarity).