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Aliases for NRIP3 Gene

Aliases for NRIP3 Gene

  • Nuclear Receptor Interacting Protein 3 2 3
  • Sarcoma Antigen NY-SAR-105 3 4
  • C11orf14 3 4
  • Nuclear Receptor-Interacting Protein 3 3
  • Chromosome 11 Open Reading Frame 14 2
  • NY-SAR-105 3

External Ids for NRIP3 Gene

Previous HGNC Symbols for NRIP3 Gene

  • C11orf14

Previous GeneCards Identifiers for NRIP3 Gene

  • GC11M009043
  • GC11M008968
  • GC11M008960
  • GC11M008673

Summaries for NRIP3 Gene

GeneCards Summary for NRIP3 Gene

NRIP3 (Nuclear Receptor Interacting Protein 3) is a Protein Coding gene. Diseases associated with NRIP3 include sarcoma. GO annotations related to this gene include aspartic-type endopeptidase activity. An important paralog of this gene is NRIP2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NRIP3 Gene

Genomics for NRIP3 Gene

Regulatory Elements for NRIP3 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for NRIP3 Gene

8,980,576 bp from pter
9,004,049 bp from pter
23,474 bases
Minus strand

Genomic View for NRIP3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NRIP3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NRIP3 Gene

Proteins for NRIP3 Gene

  • Protein details for NRIP3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nuclear receptor-interacting protein 3
    Protein Accession:
    Secondary Accessions:
    • Q86WD9

    Protein attributes for NRIP3 Gene

    241 amino acids
    Molecular mass:
    26975 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NRIP3 Gene

Proteomics data for NRIP3 Gene at MOPED

Post-translational modifications for NRIP3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NRIP3 Gene

Antibody Products

No data available for DME Specific Peptides for NRIP3 Gene

Domains for NRIP3 Gene

Protein Domains for NRIP3 Gene

Suggested Antigen Peptide Sequences for NRIP3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with NRIP3: view

No data available for Gene Families and UniProtKB/Swiss-Prot for NRIP3 Gene

Function for NRIP3 Gene

Gene Ontology (GO) - Molecular Function for NRIP3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004190 aspartic-type endopeptidase activity IEA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with NRIP3: view

Phenotypes for NRIP3 Gene

GenomeRNAi human phenotypes for NRIP3:
genes like me logo Genes that share phenotypes with NRIP3: view

Animal Model Products

miRNA for NRIP3 Gene

miRTarBase miRNAs that target NRIP3

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NRIP3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for NRIP3 Gene

Localization for NRIP3 Gene

Subcellular locations from

Jensen Localization Image for NRIP3 Gene COMPARTMENTS Subcellular localization image for NRIP3 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for NRIP3 Gene

Pathways for NRIP3 Gene

SuperPathways for NRIP3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for NRIP3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
genes like me logo Genes that share ontologies with NRIP3: view

No data available for Pathways by source for NRIP3 Gene

Transcripts for NRIP3 Gene

Unigene Clusters for NRIP3 Gene

Nuclear receptor interacting protein 3:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for NRIP3

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NRIP3 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b
SP1: -
SP2: - - -
SP3: -

Relevant External Links for NRIP3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NRIP3 Gene

mRNA expression in normal human tissues for NRIP3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NRIP3 Gene

This gene is overexpressed in Brain - Hippocampus (7.3), Brain - Cerebellum (5.6), and Brain - Cerebellar Hemisphere (5.4).

Protein differential expression in normal tissues for NRIP3 Gene

This gene is overexpressed in Retina (41.6) and Platelet (27.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for NRIP3 Gene

SOURCE GeneReport for Unigene cluster for NRIP3 Gene Hs.523467

genes like me logo Genes that share expressions with NRIP3: view

Expression partners for NRIP3 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for NRIP3 Gene

Orthologs for NRIP3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NRIP3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia NRIP3 35
  • 93.61 (n)
  • 95.83 (a)
NRIP3 36
  • 95 (a)
(Canis familiaris)
Mammalia NRIP3 35
  • 91.94 (n)
  • 92.08 (a)
NRIP3 36
  • 90 (a)
(Mus musculus)
Mammalia Nrip3 35
  • 91.39 (n)
  • 93.33 (a)
Nrip3 16
Nrip3 36
  • 93 (a)
(Pan troglodytes)
Mammalia NRIP3 35
  • 99.44 (n)
  • 99.58 (a)
NRIP3 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Nrip3 35
  • 91.67 (n)
  • 91.25 (a)
(Monodelphis domestica)
Mammalia NRIP3 36
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia NRIP3 36
  • 77 (a)
(Gallus gallus)
Aves NRIP3 35
  • 67.83 (n)
  • 66.09 (a)
NRIP3 36
  • 62 (a)
(Anolis carolinensis)
Reptilia NRIP3 36
  • 67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101732611 35
  • 65.85 (n)
  • 67.07 (a)
Species with no ortholog for NRIP3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NRIP3 Gene

Gene Tree for NRIP3 (if available)
Gene Tree for NRIP3 (if available)

Paralogs for NRIP3 Gene

Paralogs for NRIP3 Gene

(1) SIMAP similar genes for NRIP3 Gene using alignment to 5 proteins: Pseudogenes for NRIP3 Gene

genes like me logo Genes that share paralogs with NRIP3: view

Variants for NRIP3 Gene

Sequence variations from dbSNP and Humsavar for NRIP3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs35734708 -- 8,987,743(+) CTCCC(-/C)AATTA intron-variant
rs35606591 -- 8,991,802(+) TTAGG(-/G)CATAG intron-variant
rs35578021 -- 8,988,398(+) CTTTG(A/C)TTCTT intron-variant
rs35568664 -- 8,993,275(+) GAGAA(-/A)TTAAA intron-variant
rs35528175 -- 8,985,187(+) TTTTT(-/T)GAGAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NRIP3 Gene

Variant ID Type Subtype PubMed ID
nsv7215 OTHER Inversion 18451855
nsv499766 OTHER Inversion 21111241
essv24306 CNV CNV 17122850
nsv832062 CNV Loss 17160897
nsv896984 CNV Gain 21882294
esv33264 CNV Loss 17666407
nsv896985 CNV Gain 21882294
esv2670495 CNV Deletion 23128226

Relevant External Links for NRIP3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NRIP3 Gene

Disorders for NRIP3 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for NRIP3 Gene in MalaCards »

(1) Disease for NRIP3 Gene

genes like me logo Genes that share disorders with NRIP3: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for NRIP3 Gene

Publications for NRIP3 Gene

  1. Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. (PMID: 11528127) Amid C. … Schmidt E.R. (Cytogenet. Cell Genet. 2001) 2 3 4
  2. Immunomic analysis of human sarcoma. (PMID: 12601173) Lee S.-Y. … Scanlan M.J. (Proc. Natl. Acad. Sci. U.S.A. 2003) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for NRIP3 Gene

Sources for NRIP3 Gene

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