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NRIP3 Gene

protein-coding   GIFtS: 46
GCID: GC11M009001

Nuclear Receptor Interacting Protein 3

(Previous name: chromosome 11 open reading frame 14)
(Previous symbol: C11orf14)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nuclear Receptor Interacting Protein 31 2
C11orf141 2 3
Sarcoma Antigen NY-SAR-1052 3
Chromosome 11 Open Reading Frame 141
NY-SAR-1052
Nuclear Receptor-Interacting Protein 32

External Ids:    HGNC: 11671   Entrez Gene: 566752   Ensembl: ENSG000001753527   OMIM: 6131255   UniProtKB: Q9NQ353   

Export aliases for NRIP3 gene to outside databases

Previous GC identifers: GC11M009043 GC11M008968 GC11M008960 GC11M008673


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NRIP3 Gene:
NRIP3 (nuclear receptor interacting protein 3) is a protein-coding gene. Diseases associated with NRIP3 include sarcoma, and acute myeloid leukemia. GO annotations related to this gene include aspartic-type endopeptidase activity. An important paralog of this gene is NRIP2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000011.10  NC_018922.2  NT_009237.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the NRIP3 gene promoter:
         ISGF-3   LHX3b/Lhx3b   LUN-1   AREB6   CREB   Ik-2   deltaCREB   LHX3a/Lhx3a   STAT3   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNRIP3 promoter sequence
   Search Chromatin IP Primers for NRIP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NRIP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.3   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.3

NRIP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NRIP3 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M009001:  view genomic region     (about GC identifiers)

Start:
9,002,123 bp from pter      End:
9,025,596 bp from pter
Size:
23,474 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: NRIP3_HUMAN, Q9NQ35 (See protein sequence)
Recommended Name: Nuclear receptor-interacting protein 3  
Size: 241 amino acids; 26975 Da
Secondary accessions: Q86WD9

Explore the universe of human proteins at neXtProt for NRIP3: NX_Q9NQ35

Explore proteomics data for NRIP3 at MOPED


See NRIP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_065696.1  
ENSEMBL proteins: 
 ENSP00000310205   ENSP00000435785   ENSP00000432002   ENSP00000432451   ENSP00000433845  

NRIP3 Human Recombinant Protein Products:

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Novus Biologicals NRIP3 Lysate
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Cloud-Clone Corp. Proteins for NRIP3

NRIP3 Antibody Products:

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OriGene Custom Antibody Services for NRIP3
Novus Biologicals NRIP3 Antibodies
Search for Antibodies for NRIP3 at Abcam
Cloud-Clone Corp. Antibodies for NRIP3
ThermoFisher Antibodies for NRIP3
LSBio Antibodies in human, mouse, rat for NRIP3

NRIP3 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for NRIP3
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for NRIP3
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for NRIP3
Cloud-Clone Corp. CLIAs for NRIP3


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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2 InterPro protein domains:
 IPR021109 Peptidase_aspartic_dom
 IPR019103 Peptidase_aspartic_DDI1-type

Graphical View of Domain Structure for InterPro Entry Q9NQ35

ProtoNet protein and cluster: Q9NQ35


NRIP3 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004190aspartic-type endopeptidase activity IEA--
     
NRIP3 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for NRIP3:
 Increased S DNA content 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NRIP3
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NRIP3

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NRIP3
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NRIP3

miRNA
Products:
    
miRTarBase miRNAs that target NRIP3:
hsa-mir-9-5p (MIRT021324)

Block miRNA regulation of human, mouse, rat NRIP3 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate NRIP3 (see all 60):
hsa-miR-142-5p hsa-miR-3678-3p hsa-miR-3130-5p hsa-miR-26a-2* hsa-miR-1321 hsa-miR-4254 hsa-miR-429 hsa-miR-4328
SwitchGear 3'UTR luciferase reporter plasmidNRIP3 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for NRIP3
Predesigned siRNA for gene silencing in human, mouse, rat NRIP3

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for NRIP3

Clone
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OriGene clones in human, mouse for NRIP3 (see all 9)
OriGene ORF clones in mouse, rat for NRIP3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: NRIP3 (NM_020645)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NRIP3
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NRIP3

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for NRIP3
Browse ESI BIO Cell Lines and PureStem Progenitors for NRIP3 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRIP3


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
cytosol2
nucleus2
mitochondrion1

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NRIP3
Interactions:

    Search GeneGlobe Interaction Network for NRIP3

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for NRIP3 (ENSP000003102054) via UniProtKB, MINT, STRING, and/or I2D (see all 49)
InteractantInteraction Details
GeneCardExternal ID(s)
PSMC3ENSP000002988524STRING: ENSP00000298852
PSMD2ENSP000003101294STRING: ENSP00000310129
RPS27AENSP000002723174STRING: ENSP00000272317
RORCENSP000003270254STRING: ENSP00000327025
RARBENSP000003322964STRING: ENSP00000332296
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Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006508proteolysis ----

NRIP3 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for NRIP3



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for NRIP3 gene: 
NM_020645.2  

Unigene Cluster for NRIP3:

Nuclear receptor interacting protein 3
Hs.523467  [show with all ESTs]
Unigene Representative Sequence: NM_020645
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000309166(uc001mhg.2) ENST00000534759 ENST00000531142 ENST00000531090(uc010rbu.1)
ENST00000525100
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat NRIP3 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate NRIP3 (see all 60):
hsa-miR-142-5p hsa-miR-3678-3p hsa-miR-3130-5p hsa-miR-26a-2* hsa-miR-1321 hsa-miR-4254 hsa-miR-429 hsa-miR-4328
SwitchGear 3'UTR luciferase reporter plasmidNRIP3 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for NRIP3
Predesigned siRNA for gene silencing in human, mouse, rat NRIP3
Clone
Products:
     
OriGene clones in human, mouse for NRIP3 (see all 9)
OriGene ORF clones in mouse, rat for NRIP3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: NRIP3 (NM_020645)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for NRIP3
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NRIP3
Primer
Products:
    
OriGene qPCR primer pairs and template standards for NRIP3
OriGene qSTAR qPCR primer pairs in human, mouse for NRIP3
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NRIP3
  QuantiTect SYBR Green Assays in human, mouse, rat NRIP3
  QuantiFast Probe-based Assays in human, mouse, rat NRIP3

Additional mRNA sequence: 

AK024750.1 AK093229.1 AK098694.1 AK296484.1 AY211930.1 BC008835.2 

4 DOTS entries:

DT.213005  DT.95268744  DT.95268743  DT.95111301 

Selected AceView cDNA sequences (see all 87):

AI248400 AI123829 BX117508 R85059 CA446775 AA609577 AI123819 BU632617 
AI912608 BI548996 BP375819 BP371204 BF439625 AA928382 BG721039 BF237525 
AA932275 AA293782 BG717768 BF980213 AI143864 BG717689 AA669509 CB146144 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for NRIP3    About this scheme

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b
SP1:                                                              -               
SP2:                          -     -     -                                       
SP3:        -                                                                     
SP4:                                                                              
SP5:                                                                              


ECgene alternative splicing isoforms for NRIP3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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NRIP3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CCTGACTCGG
NRIP3 Expression
About this image


NRIP3 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 8) fully expand
 
 Neural Tube (Nervous System)    fully expand to see all 4 entries
         Metencephalon
 
 Brain (Nervous System)    fully expand to see all 2 entries
         Adult Dopaminergic Neurons Substantia Nigra pars Compacta
         Cerebellum
 
 Gut Tube (Gastrointestinal Tract)
         Foregut
 
 Bone (Muscoskeletal System)
         Rib
 
 Lower Urinary Tract (Urinary System)
         Ureter
NRIP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

NRIP3 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.523467
    Custom PCR Arrays for NRIP3
Primer
Products:
OriGene qPCR primer pairs and template standards for NRIP3
OriGene qSTAR qPCR primer pairs in human, mouse for NRIP3
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NRIP3
QuantiTect SYBR Green Assays in human, mouse, rat NRIP3
QuantiFast Probe-based Assays in human, mouse, rat NRIP3
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRIP3

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for NRIP3 gene from Selected species (see all 10)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Nrip31 , 5 nuclear receptor interacting protein 31, 5 91.39(n)1
93.33(a)1
  7 (57.49 cM)5
785931  NM_020610.11  NP_065635.11 
 1097580555 
chicken
(Gallus gallus)
Aves NRIP31 nuclear receptor interacting protein 3 67.83(n)
66.09(a)
  423050  XM_420983.4  XP_420983.3 
lizard
(Anolis carolinensis)
Reptilia NRIP36
nuclear receptor interacting protein 3
67(a)
1 ↔ 1
1(64441513-64481310)
tropical clawed frog
(Xenopus tropicalis)
Amphibia LOC1017326111 nuclear receptor-interacting protein 3-like 65.85(n)
67.07(a)
  101732611  XM_004921007.1  XP_004921064.1 


ENSEMBL Gene Tree for NRIP3 (if available)
TreeFam Gene Tree for NRIP3 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for NRIP3 gene
NRIP22  
1 SIMAP similar gene for NRIP3 using alignment to 5 protein entries:     NRIP3_HUMAN (see all proteins):
NRIP2

NRIP3 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for NRIP3
PGOHUM00000257922


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for NRIP3 (see all 505)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1149200281,2
F--9001653(+) GTAGAG/AAAGGG 1 -- ds50011Minor allele frequency- A:0.09WA 118
rs1154734541,2
C,F--9001693(+) GAACTC/TGTGGG 1 -- ds50011Minor allele frequency- T:0.09WA 118
rs1144004571,2
F--9001715(+) CTCCAG/ACCTCA 1 -- ds50011Minor allele frequency- A:0.08WA 118
rs1442780251,2
--9001769(+) AGCTAC/TATTTC 1 -- ds50010--------
rs1865853661,2
--9001964(+) GCTAAC/TGTGCT 1 -- ds50010--------
rs27424741,2
C,F,A,H--9002089(-) AGGGCC/TCCAGT 1 -- ds500111Minor allele frequency- T:0.45NA WA CSA EA 374
rs26536091,2
C,F--9002147(-) TGTAAC/TAATAA 1 -- ut315Minor allele frequency- T:0.14NA WA 244
rs1407404181,2
C--9002189(+) AAACAC/GTGAAA 1 -- ut310--------
rs1918173151,2
--9002279(+) GCAATA/GTATTT 1 -- ut310--------
rs1835409731,2
--9002291(+) TATTAC/TACAAG 1 -- ut310--------

HapMap Linkage Disequilibrium report for NRIP3 (9002123 - 9025596 bp)

Structural Variations
     Database of Genomic Variants (DGV) 8 variations for NRIP3:    About this table    
Variant IDTypeSubtypePubMed ID
esv2670495CNV Deletion23128226
nsv832062CNV Loss17160897
esv33264CNV Loss17666407
nsv896984CNV Gain21882294
nsv896985CNV Gain21882294
essv24306CNV CNV17122850
nsv7215OTHER Inversion18451855
nsv499766OTHER Inversion21111241

Site Specific Mutation Identification with PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing NRIP3
DNA2.0 Custom Variant and Variant Library Synthesis for NRIP3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 613125    OMIM disorders: --

7 diseases for NRIP3:    
About MalaCards
sarcoma    acute myeloid leukemia    myeloid leukemia    cystic fibrosis
leukemia    cerebritis    neuronitis


NRIP3 for disorders           About GeneDecksing


Export disorders for NRIP3 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for NRIP3 gene integrated from 10 sources:
(articles sorted by number of sources associating them with NRIP3)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. (PubMed id 11528127)1, 2, 3 Amid C.... Schmidt E.R. (Cytogenet. Cell Genet. 2001)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  4. Immunomic analysis of human sarcoma. (PubMed id 12601173)1, 2 Lee S.-Y.... Scanlan M.J. (Proc. Natl. Acad. Sci. U.S.A. 2003)
  5. NRIP3: a novel translocation partner of MLL detected in a pediatric acute myeloid leukemia with complex chromosome 11 rearrangements. (PubMed id 19454493)1 Balgobind B.V....Van den Heuvel-Eibrink M.M. (Haematologica 2009)
  6. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
  7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  8. Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. (PubMed id 17110338)1 Wang X....Balch W.E. (Cell 2006)
  9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 56675 HGNC: 1167 AceView: NRIP3 Ensembl:ENSG00000175352 euGenes: HUgn56675
ECgene: NRIP3 H-InvDB: NRIP3

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for NRIP3 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for NRIP3 gene:
Search GeneIP for patents involving NRIP3

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 OriGene Antibodies for NRIP3   OriGene RNAi products in human, mouse, rat for NRIP3  
 OriGene qPCR primer pairs and template standards for NRIP3   OriGene Protein Over-expression Lysate for NRIP3  
 OriGene MassSpec something-or-other for NRIP3   OriGene clones in human, mouse for NRIP3  
 OriGene qSTAR qPCR primer pairs in human, mouse for NRIP3   OriGene Purified Protein for NRIP3  
 OriGene ORF clones in mouse, rat for NRIP3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for NRIP3   OriGene Custom Protein Services for NRIP3  

 
 
 Block miRNA regulation of human, mouse, rat NRIP3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NRIP3
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NRIP3 Predesigned siRNA for gene silencing in human, mouse, rat NRIP3
 QuantiFast Probe-based Assays in human, mouse, rat NRIP3 QuantiTect SYBR Green Assays in human, mouse, rat NRIP3
 Custom PCR Arrays for NRIP3 Search Chromatin IP Primers for NRIP3
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NRIP3  Search GeneGlobe Interaction Network for NRIP3
 Regulatory tfbs in NRIP3 promoter
 GenScript Custom Purified and Recombinant Proteins Services for NRIP3 GenScript cDNA clones with any tag delivered in your preferred vector for NRIP3
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 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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 Search Tocris compounds for NRIP3
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 NRIP3 antibodies
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 Search for Antibodies for NRIP3 at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for NRIP3
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 Abcam protocols and scientific support
 Recombinant Protein for NRIP3
 Proteins for NRIP3
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 Browse ESI BIO Cell Lines and PureStem Progenitors for NRIP3
 Gene Synthesis
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRIP3
 SwitchGear 3'UTR luciferase reporter plasmids for NRIP3
 SwitchGear Promoter luciferase reporter plasmids for NRIP3
 ThermoFisher Antibodies for NRIP3
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NRIP3
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NRIP3
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NRIP3
 LSBio Antibodies in human, mouse, rat for NRIP3
Customized transgenic rodents for:
 Humanization
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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