Free for academic non-profit institutions. Other users need a Commercial license

Aliases for NRIP3 Gene

Aliases for NRIP3 Gene

  • Nuclear Receptor Interacting Protein 3 2 3 5
  • Sarcoma Antigen NY-SAR-105 3 4
  • C11orf14 3 4
  • Nuclear Receptor-Interacting Protein 3 3
  • Chromosome 11 Open Reading Frame 14 2
  • NY-SAR-105 3

External Ids for NRIP3 Gene

Previous HGNC Symbols for NRIP3 Gene

  • C11orf14

Previous GeneCards Identifiers for NRIP3 Gene

  • GC11M009043
  • GC11M008968
  • GC11M008960
  • GC11M008673

Summaries for NRIP3 Gene

GeneCards Summary for NRIP3 Gene

NRIP3 (Nuclear Receptor Interacting Protein 3) is a Protein Coding gene. GO annotations related to this gene include aspartic-type endopeptidase activity. An important paralog of this gene is NRIP2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NRIP3 Gene

Genomics for NRIP3 Gene

Regulatory Elements for NRIP3 Gene

Enhancers for NRIP3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around NRIP3 on UCSC Golden Path with GeneCards custom track

Promoters for NRIP3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for NRIP3 Gene

8,980,576 bp from pter
9,004,049 bp from pter
23,474 bases
Minus strand

Genomic View for NRIP3 Gene

Genes around NRIP3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NRIP3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NRIP3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NRIP3 Gene

Proteins for NRIP3 Gene

  • Protein details for NRIP3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nuclear receptor-interacting protein 3
    Protein Accession:
    Secondary Accessions:
    • Q86WD9

    Protein attributes for NRIP3 Gene

    241 amino acids
    Molecular mass:
    26975 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NRIP3 Gene

Post-translational modifications for NRIP3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for NRIP3 Gene

No data available for DME Specific Peptides for NRIP3 Gene

Domains & Families for NRIP3 Gene

Protein Domains for NRIP3 Gene

Suggested Antigen Peptide Sequences for NRIP3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with NRIP3: view

No data available for Gene Families and UniProtKB/Swiss-Prot for NRIP3 Gene

Function for NRIP3 Gene

Gene Ontology (GO) - Molecular Function for NRIP3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004190 aspartic-type endopeptidase activity IEA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with NRIP3: view
genes like me logo Genes that share phenotypes with NRIP3: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for NRIP3 Gene

Localization for NRIP3 Gene

Subcellular locations from

Jensen Localization Image for NRIP3 Gene COMPARTMENTS Subcellular localization image for NRIP3 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for NRIP3 Gene

Pathways & Interactions for NRIP3 Gene

SuperPathways for NRIP3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for NRIP3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
genes like me logo Genes that share ontologies with NRIP3: view

No data available for Pathways by source and SIGNOR curated interactions for NRIP3 Gene

Drugs & Compounds for NRIP3 Gene

No Compound Related Data Available

Transcripts for NRIP3 Gene

Unigene Clusters for NRIP3 Gene

Nuclear receptor interacting protein 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NRIP3 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b
SP1: -
SP2: - - -
SP3: -

Relevant External Links for NRIP3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NRIP3 Gene

mRNA expression in normal human tissues for NRIP3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for NRIP3 Gene

This gene is overexpressed in Brain - Hippocampus (x7.3), Brain - Cerebellum (x5.6), and Brain - Cerebellar Hemisphere (x5.4).

Protein differential expression in normal tissues from HIPED for NRIP3 Gene

This gene is overexpressed in Retina (41.6) and Platelet (27.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for NRIP3 Gene

Protein tissue co-expression partners for NRIP3 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of NRIP3 Gene:


SOURCE GeneReport for Unigene cluster for NRIP3 Gene:

genes like me logo Genes that share expression patterns with NRIP3: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for NRIP3 Gene

Orthologs for NRIP3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NRIP3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia NRIP3 34
  • 93.61 (n)
  • 95.83 (a)
NRIP3 35
  • 95 (a)
(Canis familiaris)
Mammalia NRIP3 34
  • 91.94 (n)
  • 92.08 (a)
NRIP3 35
  • 90 (a)
(Mus musculus)
Mammalia Nrip3 34
  • 91.39 (n)
  • 93.33 (a)
Nrip3 16
Nrip3 35
  • 93 (a)
(Pan troglodytes)
Mammalia NRIP3 34
  • 99.44 (n)
  • 99.58 (a)
NRIP3 35
  • 99 (a)
(Rattus norvegicus)
Mammalia Nrip3 34
  • 91.67 (n)
  • 91.25 (a)
(Monodelphis domestica)
Mammalia NRIP3 35
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia NRIP3 35
  • 77 (a)
(Gallus gallus)
Aves NRIP3 34
  • 67.83 (n)
  • 66.09 (a)
NRIP3 35
  • 62 (a)
(Anolis carolinensis)
Reptilia NRIP3 35
  • 67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101732611 34
  • 65.85 (n)
  • 67.07 (a)
Species where no ortholog for NRIP3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NRIP3 Gene

Gene Tree for NRIP3 (if available)
Gene Tree for NRIP3 (if available)

Paralogs for NRIP3 Gene

Paralogs for NRIP3 Gene

(1) SIMAP similar genes for NRIP3 Gene using alignment to 5 proteins: Pseudogenes for NRIP3 Gene

genes like me logo Genes that share paralogs with NRIP3: view

Variants for NRIP3 Gene

Sequence variations from dbSNP and Humsavar for NRIP3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1123936 -- 8,981,759(-) GGCTA(C/T)ATCTA utr-variant-3-prime
rs1980428 -- 8,988,950(-) TGCCA(A/G)CATCG intron-variant
rs1980429 -- 8,988,927(-) TGTTC(A/G/T)CTCAG intron-variant
rs1985026 -- 9,000,319(-) TAGAA(A/G)AGAAG intron-variant
rs1989143 -- 8,995,199(-) GAATG(C/G/T)TAAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NRIP3 Gene

Variant ID Type Subtype PubMed ID
esv2670495 CNV deletion 23128226
esv2759803 CNV gain 17122850
esv33264 CNV loss 17666407
esv3891928 CNV gain 25118596
nsv499766 OTHER inversion 21111241
nsv7215 OTHER inversion 18451855
nsv832062 CNV loss 17160897

Variation tolerance for NRIP3 Gene

Residual Variation Intolerance Score: 78.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.22; 40.03% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NRIP3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NRIP3 Gene

Disorders for NRIP3 Gene

Relevant External Links for NRIP3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for NRIP3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NRIP3 Gene

Publications for NRIP3 Gene

  1. Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7. (PMID: 11528127) Amid C. … Schmidt E.R. (Cytogenet. Cell Genet. 2001) 2 3 4 65
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  4. Immunomic analysis of human sarcoma. (PMID: 12601173) Lee S.-Y. … Scanlan M.J. (Proc. Natl. Acad. Sci. U.S.A. 2003) 3 4 65
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65

Products for NRIP3 Gene

Sources for NRIP3 Gene

Loading form....