NRG4 Gene
protein-coding GIFtS: 52
GCID: GC15M076233
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|
neuregulin 4
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Aliases
for NRG4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Neuregulin 41 2 | | HRG41 2 5 | | Heregulin 42 | | Pro-NRG43 | | Pro-Neuregulin-4, Membrane-Bound Isoform2 | | Pro-NRG43 |
Export aliases for NRG4 gene to outside databasesPrevious GC identifers: GC15M074022 GC15M052990 |
Summaries
for NRG4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NRG4:
The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiatingcell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 (PubMed 10348342)).(supplied by OMIM, Mar2008)
UniProtKB/Swiss-Prot: NRG4_HUMAN, Q8WWG1Function: Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does notbind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity)
Gene Wiki entry for NRG4
|
Genomic Views
for NRG4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NRG4 gene promoter:
AML1a CUTL1 IRF-1 E4BP4 HFH-1 FOXJ2 (long isoform) FOXJ2 Pax-4a TGIF Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for NRG4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NRG4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q24.2 Ensembl cytogenetic band: 15q24.2 HGNC cytogenetic band: 15q23NRG4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M076233: view genomic region
(about GC identifiers)
Start:
|
76,228,310 bp from pter |
End:
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76,352,136 bp from pter |
Size:
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123,827 bases |
Orientation:
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minus strand |
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Proteins
for NRG4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NRG4_HUMAN, Q8WWG1 (See
protein sequence)Recommended Name: Pro-neuregulin-4, membrane-bound isoform Size: 115 amino acids; 12722 Da
Subunit: Interacts with ERBB4 (By similarity)
Subcellular location: Pro-neuregulin-4, membrane-bound isoform: Cell membrane; Single-pass type I membrane protein (Bysimilarity). Note=Does not seem to be active (By similarity)
Subcellular location: Neuregulin-4: Secreted (By similarity)
Secondary accessions: A6NIE8Explore the universe of human proteins at neXtProt for NRG4: NX_Q8WWG1
Post-translational modifications:
Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growthfactor form (By similarity)1
Extensive glycosylation precedes the proteolytic cleavage (By similarity)1
View neXtProt modification sites for NX_Q8WWG1
NRG4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_612640.1
ENSEMBL proteins: ENSP00000457335 ENSP00000431810 ENSP00000432751 ENSP00000378367 ENSP00000456778 ENSP00000457838 ENSP00000454895 ENSP00000456029 ENSP00000455314 ENSP00000455167 ENSP00000436832 ENSP00000457626 ENSP00000441129 ENSP00000303071 Reactome Protein details: Q8WWG1
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
NRG4 for ontologies About GeneDecksing
NRG4 Antibody Products:
Assay Products for NRG4: |
Protein
Domains /
Families
for NRG4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NRG4 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8WWG1ProtoNet protein and cluster: Q8WWG1 1 Blocks protein family: IPB006210 Type I EGF
UniProtKB/Swiss-Prot: NRG4_HUMAN, Q8WWG1Domain: The cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulationof the proteolytic processing involves initial intracellular domain dimerization (By similarity)Domain: ERBB receptor binding is elicited entirely by the EGF-like domain (By similarity)Similarity: Belongs to the neuregulin familySimilarity: Contains 1 EGF-like domain |
Function
for NRG4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NRG4_HUMAN, Q8WWG1Function: Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does notbind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NRG4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NRG4
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: NRG4 (NM_138573) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NRG4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NRG4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRG4 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008083 | growth factor activity |
IEA | -- |
NRG4 for ontologies About GeneDecksing
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Nrg4):
NRG4 for phenotypes About GeneDecksing
|
Pathways & Interactions
for NRG4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/11 super-pathways (see all 11) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling by FGFR | | | 2 | PIP3 activates AKT signaling | | | 3 | SHC1 events in ERBB2 signaling | | | 4 | Immune System | | | 5 | Signaling by the B Cell Receptor (BCR) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for NRG4
1  GeneGo (Thomson Reuters) Pathway for NRG4
3  BioSystems Pathways for NRG4
5/33 
Reactome Pathways for NRG4 (see all 33)
1 
Kegg Pathway (Kegg details for NRG4):
NRG4 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NRG4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/11 Interacting proteins for NRG4 (Q8WWG13 ENSP000003783674) via UniProtKB, MINT, STRING, and/or I2D (see all 11)About this table
|
Drugs & Compounds
for NRG4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
NRG4 for compounds About GeneDecksing
 Browse Tocris compounds for NRG4
1 Novoseek chemical compound relationship for NRG4 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tyrosine |
24.9 |
1 |
10348342 (1) |
Search CenterWatch for drugs/clinical trials and news about NRG4
|
Transcripts
for NRG4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NRG4 gene: NM_138573.3 Unigene Cluster for NRG4: Neuregulin 4 Hs.732438 [show with all ESTs]Unigene Representative Sequence: CR74951918 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000567467 ENST00000569343 ENST00000566417 ENST00000461391(uc002bbo.3)
ENST00000472094 ENST00000394907 ENST00000568073(uc010bkm.1) ENST00000565661
ENST00000562114 ENST00000567936 ENST00000563204(uc002bbp.2) ENST00000563910
ENST00000498750 ENST00000567126 ENST00000568203 ENST00000563582 ENST00000535975
ENST00000305435
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NRG4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NRG4
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: NRG4 (NM_138573) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NRG4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NRG4 |
Additional cDNA sequence: AK307362.1 AM392364.1 AM392365.1 AM392366.1 BC017568.1 CR749519.1 7 DOTS entries: DT.92420331 DT.101976338 DT.121074058 DT.40225171 DT.121074034 DT.91807155 DT.97806293 24/25 AceView cDNA sequences (see all 25): AA861006 BF061527 CN478955 F29883 BC017568 BM797082 BI464093 BF793585 NM_138573 AA884717 BE787057 BX538100 CR749519 AI743118 BG195285 BX095400 CA450218 BE706435 H56479 BG207240 C00540 BG217742 H56480 BF126566
GeneLoc Exon Structure
|
Expression
for NRG4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NRG4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See NRG4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NRG4
SOURCE GeneReport for Unigene cluster: Hs.732438
SABiosciences Expression via Pathway-Focused PCR Array including NRG4:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NRG4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NRG4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NRG4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NRG4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRG4 |
Orthologs
for NRG4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for NRG4 gene from 2/7 species (see all 7) About this table
ENSEMBL Gene Tree for NRG4 (if available)
TreeFam Gene Tree for NRG4 (if available) |
Paralogs
for NRG4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for NRG4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NRG4 (76228310 - 76352136 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NRG4: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NRG4 |
|
Disorders
/ Diseases
for NRG4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NRG4 for disorders About GeneDecksing
OMIM gene information: 610894
OMIM disorders: --
5  diseases for NRG4: About MalaCardstransitional cell carcinoma breast cancer prostate cancer prostatitis
carcinoma
2 Novoseek disease relationships for NRG4 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| breast cancer |
21 |
2 |
15141382 (2) |
| tumors |
0 |
6 |
16469638 (1) |
Human Genome Epidemiology (HuGE) Navigator: NRG4 (3 documents)
Export disorders for NRG4 gene to outside databases
|
Publications
for NRG4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NRG4 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with NRG4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinase. (PubMed id 10348342)1, 9 Harari D....Yarden Y. (1999)
- Expression of HER3, HER4 and their ligand heregulin-4 is associated with better survival in bladder cancer patients. (PubMed id 15583696)1, 9 Memon A.A....Nexo E. (2004)
- Characterization of the cell membrane-associated products of the Neuregulin 4 gene. (PubMed id 17684490)1, 9 Hayes N.V....Gullick W.J. (2008)
- Identification and characterization of novel spliced variants of neuregulin 4 in prostate cancer. (PubMed id 17545517)1, 9 Hayes N.V....Gullick W.J. (2007)
- Neuregulin-4 is a survival factor for colon epithelial cells both in culture and in vivo. (PubMed id 23033483)1 Bernard J.K....Frey M.R. (2012)
- The role of neuregulin4 and HER4 in gastrointestinal malignant lymphoma. (PubMed id 21805036)1 Ebi M....Joh T. (2011)
- Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
- Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
|
External Searches for NRG4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NRG4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NRG4 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NRG4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NRG4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for NRG4 gene:
Search GeneIP for patents involving NRG4
Licensable Technologies for NRG4 gene:GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NRG4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NRG4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NRG4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NRG4 | | | OriGene Protein Over-expression Lysate for NRG4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NRG4 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NRG4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NRG4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NRG4 | | OriGene Custom Protein Services for NRG4 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NRG4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NRG4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NRG4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NRG4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NRG4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NRG4 |
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 |  |  |  | |
| | | | Search Tocris compounds for NRG4 |
| |  |  |  |  | | | | |
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 | | | NRG4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRG4 |
|  |  |  | | | | Search ThermoFisher Antibodies for NRG4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NRG4 |
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