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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NREP Gene

protein-coding   GIFtS: 48
GCID: GC05M110999

neuronal regeneration related protein

(Previous names: chromosome 5 open reading frame 13, neuronal regeneration...)
(Previous symbol: C5orf13)
 Explore 6 diseases affiliated with
NREP via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NREP    

Aliases
for NREP gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Neuronal Regeneration Related Protein1 2     Neuronal Protein 3.12 3
C5orf131 2 3 5     Protein P3112 3
P3111 2 3 5     Chromosome 5 Open Reading Frame 131
PTZ171 2 5     Neuronal Regeneration Related Protein Homolog (Rat)1
D4S1141 2     Neuronal Regeneration Related Protein Homolog2
PRO18731 2     Neuronal Regeneration-Related Protein2
SEZ171 2     

External Ids:    HGNC: 168341   Entrez Gene: 93152   Ensembl: ENSG000001349867   OMIM: 6073325   UniProtKB: Q166123   

Export aliases for NREP gene to outside databases


Summaries
for NREP gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: NREP_HUMAN, Q16612
Function: May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal
regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces
differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid
regulation of lipid-droplet biogenesis (By similarity)

Gene Wiki entry for NREP (C5orf13)


Genomic Views
for NREP gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_034772.6  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for NREP
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NREP promoter sequence
   Search SABiosciences Chromatin IP Primers for NREP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NREP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q22.1   Ensembl cytogenetic band:  5q22.1   HGNC cytogenetic band: 5q22.1

NREP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NREP gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M110999:  view genomic region     (about GC identifiers)

Start:
 110,998,318 bp from pter      End:
 111,333,161 bp from pter
Size:
 334,844 bases      Orientation:
 minus strand

Proteins
for NREP gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NREP_HUMAN, Q16612 (See protein sequence)
Recommended Name: Neuronal regeneration-related protein  
Size: 68 amino acids; 7909 Da
Subunit: Interacts with FLNA
Subcellular location: Cytoplasm
Secondary accessions: B2RDN8 B7Z5D2 D3DSZ8
Alternative splicing: 2 isoforms:  Q16612-1   Q16612-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NREP: NX_Q16612

Post-translational modifications:

  • Phosphorylated on Ser-59. Phosphorylation decreases stability and activity1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q16612

    • NREP Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (11 alternative transcripts): 
    NP_001135946.1  NP_001135947.1  NP_001135948.1  NP_001135949.1  NP_001135950.1  NP_001135951.1  NP_001135952.1  NP_001135953.1  
    NP_001135954.1  NP_001135955.1  NP_004763.1  

    ENSEMBL proteins: 
     ENSP00000427595   ENSP00000426834   ENSP00000368993   ENSP00000257435   ENSP00000402965  
     ENSP00000378996   ENSP00000422278   ENSP00000423320   ENSP00000416617   ENSP00000399766  
     ENSP00000422630   ENSP00000403383   ENSP00000392559   ENSP00000427149   ENSP00000427476  
     ENSP00000422046   ENSP00000422514   ENSP00000408839  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: NREP
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    Novus Biologicals NREP Protein
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NREP

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--


    NREP for ontologies           About GeneDecksing



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    Uscn Antibodies for NREP
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    Uscn ELISAs and CLIAs for NREP

    Protein Domains /
    Families
    for NREP gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NREP for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR024417 Neuronal_3.1

    Graphical View of Domain Structure for InterPro Entry Q16612

    ProtoNet protein and cluster: Q16612


    Function
    for NREP gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NREP_HUMAN, Q16612
    Function: May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal
    regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces
    differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid
    regulation of lipid-droplet biogenesis (By similarity)

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: NREP
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    Gene Editing
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    Clone
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    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----


    NREP for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for NREP:
     Increased gamma-H2AX phosphory  Large nuclei 

    Animal Models:
         Mouse knock-out Nreptm1Wcw for NREP
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Nrep):
     behavior/neurological 

    NREP for phenotypes           About GeneDecksing


    Pathways & Interactions
    for NREP gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NREP

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for NREP (Q166122, 3 ENSP000004033834) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MLL4Q9UMN62, 3, ENSP000002222704MINT-8249964 I2D: score=2 STRING: ENSP00000222270
    EEF1A1P681042, 3MINT-8249953 I2D: score=2 
    IGSF21Q96ID52, 3, ENSP000002512964MINT-64285 I2D: score=4 STRING: ENSP00000251296
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0017015regulation of transforming growth factor beta receptor signaling pathway IEA--
    GO:0031103axon regeneration IEA--
    GO:0045664regulation of neuron differentiation IEA--


    NREP for ontologies           About GeneDecksing



    Drugs & Compounds
    for NREP gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NREP
    Search CenterWatch for drugs/clinical trials and news about NREP 

    Transcripts
    for NREP gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NREP gene (11 alternative transcripts): 
    NM_001142474.1  NM_001142475.1  NM_001142476.1  NM_001142477.1  NM_001142478.1  NM_001142479.1  NM_001142480.1  NM_001142481.1  
    NM_001142482.1  NM_001142483.1  NM_004772.2  

    Unigene Clusters for NREP:

    Neuronal regeneration related protein
    Hs.36053  [show with all ESTs], Hs.743959  [show with all ESTs]
    Unigene Representative Sequences: CR749489, NM_001142483
    18/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):
    ENST00000514515(uc003kpk.3) ENST00000509025 ENST00000379671(uc011cvo.2)
    ENST00000257435(uc003kpm.3 uc011cvp.2 uc011cvq.2 uc011cvr.2 uc011cvs.2)
    ENST00000446294(uc011cvk.2 uc011cvl.2 uc011cvm.2 uc011cvn.2)
    ENST00000395634 ENST00000515855 ENST00000507742 ENST00000509979 ENST00000450761
    ENST00000419114 ENST00000509427 ENST00000453526 ENST00000455559 ENST00000508870
    ENST00000513100 ENST00000504018 ENST00000508161

    miRNA
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    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AF119859.1 AK298779.1 AK307346.1 AK309667.1 AK310585.1 AK315617.1 BC011050.1 BC019068.2 
    BC072013.1 BC072443.1 U30521.1 U36189.1 

    24/46 DOTS entries (see all 46):

    DT.100846375  DT.95080590  DT.420637  DT.100846383  DT.100846378  DT.100846365  DT.101974074  DT.207399 
    DT.92461153  DT.121468359  DT.100730958  DT.100659343  DT.100766891  DT.100809932  DT.97841224  DT.87015645 
    DT.95080645  DT.100846382  DT.120846838  DT.100772303  DT.99981881  DT.120846737  DT.100846374  DT.120846766 

    24/804 AceView cDNA sequences (see all 804):

    BX460265 BE501935 T35746 AA358206 CR610267 F09715 AW078931 AI539519 
    AA993789 AI753231 CR602516 CR601940 AI130935 AW044462 BM466166 CR597011 
    BU786930 CR605504 T31511 N83555 AI937061 BM722746 CR607755 T33349 

    GeneLoc Exon Structure

    5/19 Alternative Splicing Database (ASD) splice patterns (SP) for NREP (see all 19)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c · 8d · 8e · 8f ·
    SP1:                          -     -     -     -     -     -     -     -           -     -                 -     -                                             
    SP2:                          -     -     -     -     -     -     -     -           -     -                 -     -     -                                       
    SP3:                                -     -     -     -     -     -     -           -     -                 -     -     -                                       
    SP4:                                -     -     -     -     -     -     -           -                       -     -     -                                       
    SP5:                          -     -     -     -     -     -     -     -           -     -                 -     -     -                                       

    ExUns: 8g · 8h · 8i · 8j · 8k · 8l · 8m
    SP1:                                          
    SP2:                                          
    SP3:                                          
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for NREP

    Expression
    for NREP gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NREP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACAAGTACCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NREP expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainBlood Brain BarrierPostnatal Endothelial CellsBlood Brain Barrier, Endothelium
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 4 LifeMap Cells 
    NameCategory
    PureStem™ mesenchymal progenitor E15 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ progenitor T36 (Embryonic Progenitor Cell)
    N2/LSB/S/F8/CHIR-induced cells (Generation of midbra...)
    Posterior foregut-like cells (A scalable, suspensi...)

    See NREP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NREP

    SOURCE GeneReport for Unigene clusters: Hs.36053 Hs.743959
        SABiosciences Custom PCR Arrays for NREP
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    In Situ
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    Orthologs
    for NREP gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for NREP gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Nrep5
    D0H4S1141    		 DNA segment, human D4S1141, 5 82.35(n)1
    76.47(a)1    		   18 (18.18 cM)5
    275281  NM_001109988.11  NP_001103458.11 
     334370195 
    chicken
    (Gallus gallus)    		 Aves C5orf136
    		 P311 POU
    		 40(a)
    		 1 ↔ 1
    		 Z(45605089-45623694)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.3552 Xenopus laevis gene 12-3 mRNA 83.38(n)    U41854.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii 570441002   -- 82.65(n)    57044100 


    ENSEMBL Gene Tree for NREP (if available)
    TreeFam Gene Tree for NREP (if available) 

    Paralogs
    for NREP gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NREP gene
    1 SIMAP similar gene for NREP using alignment to 5 protein entries:     NREP_HUMAN (see all proteins):
    LOC392642

    NREP for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for NREP
    PGOHUM00000233149 PGOHUM00000249663


    Genomic Variants
    for NREP gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4402 NCBI SNPs in NREP are shown (see all 4402)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 5 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs789653861,2
    		--106272413(+) CGAAGG/CATGCA 2 -- int13Minor allele frequency- C:0.21CSA WA 121
    rs794911711,2
    		--106273032(+) CAAAAC/GTCAAT 2 -- int10--------
    rs747408191,2
    		C,F,--106273382(+) TGACCC/TTTTCA 2 -- int12Minor allele frequency- T:0.07WA EA 238
    rs794101461,2
    		--106273573(+) AGGGCG/TCACCA 2 -- int12Minor allele frequency- T:0.19CSA WA 120
    rs789581141,2
    		C,F,--106273634(+) CTTCTA/GCAAGG 2 -- int12Minor allele frequency- G:0.09WA NA 238
    rs737873731,2
    		C,F,--106274015(+) CATTCT/CTGAGT 2 -- int13Minor allele frequency- C:0.18WA CSA 122
    rs757647771,2
    		C,F,--106274746(+) TCGTAG/CGGAGG 2 -- int13Minor allele frequency- C:0.07WA NA EA 358
    rs77051081,2
    		A--106274796(+) TTGTCA/GTCTGG 2 -- int10--------
    rs789948251,2
    		C,F,--106275076(+) ATCCAG/CATGGT 2 -- int14Minor allele frequency- C:0.26CSA WA NA 242
    rs355507181,2
    		C,F,--106275391(+) TGTGGC/TCTTGG 2 -- int13Minor allele frequency- T:0.33NA 6

    HapMap Linkage Disequilibrium report for NREP (110998318 - 111248318 bp, first 250kb of NREP)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for NREP: --

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    Disorders / Diseases
    for NREP gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NREP for disorders           About GeneDecksing

    OMIM gene information: 607332    OMIM disorders: --

    6 diseases for NREP:    About MalaCards
    neuronitis    rheumatoid arthritis    seizures    arthritis
    lung cancer    glioblastoma


    Export disorders for NREP gene to outside databases

    Publications
    for NREP gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NREP gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with NREP)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Regulation of glioma cell migration by serine-phosphorylated P311. (PubMed id 16229809)1, 2 McDonough W.S....Berens M.E. (2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. P311 accelerates nerve regeneration of the axotomized facial nerve. (PubMed id 15485502)1, 3 Fujitani M....Yamashita T. (2004)
    5. Metallothionein mediates gene expression of 3.1 mRNA (PTZ17) related to epileptic seizure. (PubMed id 10981724)1, 3 Miura N. and Naganuma A. (2000)
    6. An abundant mRNA of the embryonic brain persists at a high level in cerebellum, hippocampus and olfactory bulb during adulthood. (PubMed id 8261136)1, 3 Studler J.M....Levi-Strauss M. (1993)
    7. P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype. (PubMed id 12417574)1, 9 Pan D....Schuger L. (2002)
    8. [Analysis of the binding domain of hydroxypyruvate iso merase homologues in hypertrophic scar fibroblasts]. (PubMed id 22490543)1 Wang J....Zhao Y. (2012)
    9. Dlxin-1, a member of MAGE family, inhibits cell proli feration, invasion and tumorigenicity of glioma stem cells. (PubMed id 21109781)1 Reddy E.M....Shiras A. (2011)
    10. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)

    External Searches for NREP gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing NREP gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9315 HGNC: 16834 AceView: C5orf13 Ensembl:ENSG00000134986 euGenes: HUgn9315
    ECgene: NREP H-InvDB: NREP

    Other Databases showing NREP gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing NREP gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NREP Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NREP gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NREP gene:
    Search GeneIP for patents involving NREP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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