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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NREP Gene

protein-coding   GIFtS: 48
GCID: GC05M110999

Neuronal Regeneration Related Protein

(Previous names: chromosome 5 open reading frame 13, neuronal regeneration...)
(Previous symbol: C5orf13)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Neuronal Regeneration Related Protein1 2     Neuronal Regeneration Related Protein Homolog (Rat)1
C5orf131 2 3 5     D4S1142
Neuronal Protein 3.11 2 3     PRO18732
P3112 3 5     SEZ172
Protein P3112 3     Neuronal Regeneration Related Protein Homolog2
PTZ172 5     Neuronal Regeneration-Related Protein2
Chromosome 5 Open Reading Frame 131     

External Ids:    HGNC: 168341   Entrez Gene: 93152   Ensembl: ENSG000001349867   OMIM: 6073325   UniProtKB: Q166123   

Export aliases for NREP gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for NREP Gene: 
NREP (neuronal regeneration related protein) is a protein-coding gene. Diseases associated with NREP include neuronitis, and hypertrophic scars.

UniProtKB/Swiss-Prot: NREP_HUMAN, Q16612
Function: May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal
regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces
differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid
regulation of lipid-droplet biogenesis (By similarity). Down-regulates the expression of TGFB1 and TGFB2 but not
of TGFB3 (By similarity). May play a role in the regulation of alveolar generation

Gene Wiki entry for NREP (C5orf13) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_034772.6  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for NREP
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNREP promoter sequence
   Search SABiosciences Chromatin IP Primers for NREP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NREP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q22.1   Ensembl cytogenetic band:  5q22.1   HGNC cytogenetic band: 5q22.1

NREP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NREP gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M110999:  view genomic region     (about GC identifiers)

Start:
110,998,318 bp from pter      End:
111,333,161 bp from pter
Size:
334,844 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NREP_HUMAN, Q16612 (See protein sequence)
Recommended Name: Neuronal regeneration-related protein  
Size: 68 amino acids; 7909 Da
Subunit: Interacts with the latency-associated peptides (LAP) of TGFB1 and TGFB2; the interaction results in a
decrease in TGFB autoinduction (By similarity). Interacts with FLNA
Subcellular location: Cytoplasm
Developmental stage: In embryos of gestational week (gw) 24, detected mostly in the epithelial cells of saccular
surfaces. In gw 39, detected in the cells lining the alveolar surfaces as well as in the mesenchyme (at protein
level)
Secondary accessions: B2RDN8 B7Z5D2 D3DSZ8
Alternative splicing: 2 isoforms:  Q16612-1   Q16612-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for NREP: NX_Q16612

Explore proteomics data for NREP at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated on Ser-59. Phosphorylation decreases stability and activity
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q16612

  • NREP Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    NREP Protein Expression
    REFSEQ proteins (11 alternative transcripts): 
    NP_001135946.1  NP_001135947.1  NP_001135948.1  NP_001135949.1  NP_001135950.1  NP_001135951.1  NP_001135952.1  NP_001135953.1  
    NP_001135954.1  NP_001135955.1  NP_004763.1  

    ENSEMBL proteins: 
     ENSP00000427595   ENSP00000426834   ENSP00000368993   ENSP00000257435   ENSP00000402965  
     ENSP00000378996   ENSP00000422278   ENSP00000423320   ENSP00000416617   ENSP00000399766  
     ENSP00000422630   ENSP00000403383   ENSP00000392559   ENSP00000427149   ENSP00000427476  
     ENSP00000422046   ENSP00000422514   ENSP00000408839  

    Human Recombinant Protein Products for NREP: 
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    Novus Biologicals NREP Proteins
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--

    NREP for ontologies           About GeneDecksing



    NREP Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR024417 Neuronal_3.1

    Graphical View of Domain Structure for InterPro Entry Q16612

    ProtoNet protein and cluster: Q16612


    NREP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NREP_HUMAN, Q16612
    Function: May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal
    regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces
    differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid
    regulation of lipid-droplet biogenesis (By similarity). Down-regulates the expression of TGFB1 and TGFB2 but not
    of TGFB3 (By similarity). May play a role in the regulation of alveolar generation
    Induction: Down-regulated in emphysematous lung compared to normal lung

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    NREP for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for NREP:
     Increased gamma-H2AX phosphory  Large nuclei 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Nrep):
     behavior/neurological 

    NREP for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Nreptm1Wcw for NREP

       inGenious Targeting Laboratory - Custom generated mouse model solutions for NREP 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NREP

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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NREP


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for NREP

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/6 Interacting proteins for NREP (Q166121, 2, 3 ENSP000004033834) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EEF1A1P681042, 3MINT-8249953 I2D: score=2 
    KMT2BQ9UMN62, 3MINT-8249964 I2D: score=2 
    IGSF21Q96ID52, 3, ENSP000002512964MINT-64285 I2D: score=4 STRING: ENSP00000251296
    EIF6P565371EBI-718657,EBI-372243
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0017015regulation of transforming growth factor beta receptor signaling pathway IEA--
    GO:0031103axon regeneration IEA--
    GO:0045664regulation of neuron differentiation IEA--

    NREP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for NREP

    Search CenterWatch for drugs/clinical trials and news about NREP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for NREP gene (11 alternative transcripts): 
    NM_001142474.1  NM_001142475.1  NM_001142476.1  NM_001142477.1  NM_001142478.1  NM_001142479.1  NM_001142480.1  NM_001142481.1  
    NM_001142482.1  NM_001142483.1  NM_004772.2  

    Unigene Clusters for NREP:

    Neuronal regeneration related protein
    Hs.36053  [show with all ESTs], Hs.745061  [show with all ESTs]
    Unigene Representative Sequences: NM_001142483, CR749489
    18/23 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):
    ENST00000514515(uc003kpk.3) ENST00000509025 ENST00000379671(uc011cvo.2)
    ENST00000257435(uc003kpm.3 uc011cvp.2 uc011cvq.2 uc011cvr.2 uc011cvs.2)
    ENST00000446294(uc011cvk.2 uc011cvl.2 uc011cvm.2 uc011cvn.2)
    ENST00000395634 ENST00000515855 ENST00000507742 ENST00000509979 ENST00000450761
    ENST00000419114 ENST00000509427 ENST00000453526 ENST00000455559 ENST00000508870
    ENST00000513100 ENST00000504018 ENST00000508161
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidNREP 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK021624.1 CR749489.1 NR_040093.1 

    24/46 DOTS entries (see all 46):

    DT.100846375  DT.95080590  DT.420637  DT.100846383  DT.100846378  DT.100846365  DT.101974074  DT.207399 
    DT.92461153  DT.121468359  DT.100730958  DT.100659343  DT.100766891  DT.100809932  DT.97841224  DT.87015645 
    DT.95080645  DT.100846382  DT.120846838  DT.100772303  DT.99981881  DT.120846737  DT.100846374  DT.120846766 

    24/804 AceView cDNA sequences (see all 804):

    BM973170 BE766168 AL544003 BU786930 CR611162 BM876293 AI539519 BQ012000 
    AA918704 CR608957 F20351 T35746 BE765913 AI492454 BM722746 AI203562 
    BM469599 BC072443 AI332828 AA976222 AA343357 AW615304 D55780 BM510484 

    GeneLoc Exon Structure

    5/19 Alternative Splicing Database (ASD) splice patterns (SP) for NREP (see all 19)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c · 8d · 8e · 8f ·
    SP1:                          -     -     -     -     -     -     -     -           -     -                 -     -                                             
    SP2:                          -     -     -     -     -     -     -     -           -     -                 -     -     -                                       
    SP3:                                -     -     -     -     -     -     -           -     -                 -     -     -                                       
    SP4:                                -     -     -     -     -     -     -           -                       -     -     -                                       
    SP5:                          -     -     -     -     -     -     -     -           -     -                 -     -     -                                       

    ExUns: 8g · 8h · 8i · 8j · 8k · 8l · 8m
    SP1:                                          
    SP2:                                          
    SP3:                                          
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for NREP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NREP expression in normal human tissues (normalized intensities)      NREP embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACAAGTACCC
    NREP Expression
    About this image


    NREP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/11 selected tissues (see all 11) fully expand
     
     Brain (Nervous System)    fully expand to see all 19 entries
             Endothelial Cells Blood Brain Barrier
             Thalamus
             N2/LSB/S/F8/CHIR-induced cells ( Generation of midbrain dopaminergic, forebrain and...
             Olfactory Bulb   
     
     Blood Brain Barrier (Nervous System)    fully expand to see all 2 entries
             Endothelial Cells Blood Brain Barrier
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             Endothelial Cells Blood Brain Barrier
     
     Epiblast (Early Embryonic Tissues)    fully expand to see all 2 entries
             Epiblast Stem Cell line 5
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow

    See NREP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NREP

    SOURCE GeneReport for Unigene clusters: Hs.36053 Hs.745061

    UniProtKB/Swiss-Prot: NREP_HUMAN, Q16612
    Tissue specificity: Expressed in lung (at protein level)

        SABiosciences Custom PCR Arrays for NREP
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NREP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for NREP gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nrep5
    D0H4S1141
    DNA segment, human D4S1141, 5 82.35(n)1
    76.47(a)1
      18 (18.18 cM)5
    275281  NM_001109988.11  NP_001103458.11 
     334370195 
    chicken
    (Gallus gallus)
    Aves C5ORF136
    neuronal protein 3.1
    40(a)
    1 ↔ 1
    Z(46263610-46283078)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.3552 Xenopus laevis gene 12-3 mRNA 83.38(n)    U41854.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570441002   -- 82.65(n)    57044100 


    ENSEMBL Gene Tree for NREP (if available)
    TreeFam Gene Tree for NREP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NREP gene
    1 SIMAP similar gene for NREP using alignment to 5 protein entries:     NREP_HUMAN (see all proteins):
    LOC392642

    NREP for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for NREP
    PGOHUM00000233149 PGOHUM00000249663


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3457 SNPs in NREP are shown (see all 3457)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0512384
    ----see VAR_0512382 E G mis40--------
    rs37339941,2
    C--106271941(+) GCGCGA/CGCGCC 2 -- int10--------
    rs1423872591,2
    --106271958(+) CCCCGC/TACCCG 2 -- int10--------
    rs1876147021,2
    --106272068(+) GGAGCA/GCGGCG 2 -- int10--------
    rs2018980381,2
    --106272081(+) GCAAA-/TTCCCC 2 -- int10--------
    rs1931773421,2
    --106272399(+) ACACAA/CAGAGT 2 -- int10--------
    rs789653861,2
    C,F--106272413(+) CGAAGG/CATGCA 2 -- int13Minor allele frequency- C:0.21CSA WA 121
    rs1513068371,2
    --106272609(+) GTGATC/GGGCCC 2 -- int10--------
    rs1405945781,2
    C--106272610(+) TGATCA/GGCCCA 2 -- int10--------
    rs2015344831,2
    --106272692(+) TTTTT-/AAAAAT 2 -- int10--------

    HapMap Linkage Disequilibrium report for NREP (110998318 - 111248318 bp, first 250kb of NREP)

    Structural Variations
          Database of Genomic Variants (DGV) variations for NREP: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing NREP
    DNA2.0 Custom Variant and Variant Library Synthesis for NREP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607332    OMIM disorders: --

    6 diseases for NREP:    About MalaCards
    neuronitis    hypertrophic scars    glioblastoma    rheumatoid arthritis
    arthritis    lung cancer


    NREP for disorders           About GeneDecksing


    Export disorders for NREP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NREP gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with NREP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of P311 as a potential gene regulating alveolar generation. (PubMed id 16484684)1, 2 Zhao L....Vu T.H. (2006)
    2. Regulation of glioma cell migration by serine-phosphorylated P311. (PubMed id 16229809)1, 2 McDonough W.S....Berens M.E. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. P311 accelerates nerve regeneration of the axotomized facial nerve. (PubMed id 15485502)1, 3 Fujitani M....Yamashita T. (2004)
    6. Metallothionein mediates gene expression of 3.1 mRNA (PTZ17) related to epileptic seizure. (PubMed id 10981724)1, 3 Miura N. and Naganuma A. (2000)
    7. An abundant mRNA of the embryonic brain persists at a high level in cerebellum, hippocampus and olfactory bulb during adulthood. (PubMed id 8261136)1, 3 Studler J.M....Levi-Strauss M. (1993)
    8. P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype. (PubMed id 12417574)1, 9 Pan D....Schuger L. (2002)
    9. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    10. [Effects of P 311 on the migration of epidermal stem c ells in mice with superficial partial-thickness burn and injured cell model in v itro]. (PubMed id 22967977)1 Sun W....Luo G.X. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9315 HGNC: 16834 AceView: C5orf13 Ensembl:ENSG00000134986 euGenes: HUgn9315
    ECgene: NREP H-InvDB: NREP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NREP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for NREP gene:
    Search GeneIP for patents involving NREP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

     
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