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NRBP2 Gene

protein-coding   GIFtS: 48
GCID: GC08M144919

Nuclear Receptor Binding Protein 2

  See NRBP2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Nuclear Receptor Binding Protein 21 2     Transformation-Related Protein 162
TRG162     TRG-163
Nuclear Receptor-Binding Protein 22     Transformation-Related Gene 16 Protein3
pp93202     

External Ids:    HGNC: 193391   Entrez Gene: 3403712   Ensembl: ENSG000001851897   OMIM: 6155635   UniProtKB: Q9NSY03   

Export aliases for NRBP2 gene to outside databases

Previous GC identifers: GC08M144988 GC08M144917 GC08M140168


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for NRBP2 Gene:
NRBP2 (nuclear receptor binding protein 2) is a protein-coding gene. Diseases associated with NRBP2 include medulloblastoma. GO annotations related to this gene include protein kinase activity and nucleotide binding. An important paralog of this gene is WNK1.

UniProtKB/Swiss-Prot: NRBP2_HUMAN, Q9NSY0
Function: May regulate apoptosis of neural progenitor cells during their differentiation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NT_008046.17  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the NRBP2 gene promoter:
         Egr-3   Spz1   AML1a   Sp1   STAT5A   LCR-F1   FOXO4   ZIC2/Zic2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): NRBP2 promoter sequence
   Search Chromatin IP Primers for NRBP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NRBP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.3   Ensembl cytogenetic band:  8q24.3   HGNC cytogenetic band: 8q24.3

NRBP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NRBP2 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M144919:  view genomic region     (about GC identifiers)

Start:
144,915,755 bp from pter      End:
144,924,200 bp from pter
Size:
8,446 bases      Orientation:
minus strand

1 alternative location:
Chr8-,NW_003315923 172,230-179,619     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NRBP2_HUMAN, Q9NSY0 (See protein sequence)
Recommended Name: Nuclear receptor-binding protein 2  
Size: 501 amino acids; 57803 Da
Sequence caution: Sequence=AAI13874.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;
Sequence=CAB70864.1; Type=Miscellaneous discrepancy; Note=Wrong choice of CDS;
Secondary accessions: B4DF59 Q2HIX8 Q597G7 Q8NCX8 Q8WYS5
Alternative splicing: 4 isoforms:  Q9NSY0-3   Q9NSY0-2   Q9NSY0-4   Q9NSY0-5   (No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for NRBP2: NX_Q9NSY0

Explore proteomics data for NRBP2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NRBP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_848659.2  
    ENSEMBL proteins: 
     ENSP00000414055   ENSP00000431280   ENSP00000432374   ENSP00000330271  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    IUPHAR Guide to PHARMACOLOGY protein family classification: nuclear receptor binding protein 2
    NRBP family

    2 InterPro protein domains:
     IPR011009 Kinase-like_dom
     IPR000719 Prot_kinase_dom

    Graphical View of Domain Structure for InterPro Entry Q9NSY0

    ProtoNet protein and cluster: Q9NSY0

    UniProtKB/Swiss-Prot: NRBP2_HUMAN, Q9NSY0
    Domain: The protein kinase domain is predicted to be catalytically inactive
    Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family
    Similarity: Contains 1 protein kinase domain


    Find genes that share domains with NRBP2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NRBP2_HUMAN, Q9NSY0
    Function: May regulate apoptosis of neural progenitor cells during their differentiation (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity IEA--
    GO:0004713protein tyrosine kinase activity ----
    GO:0005524ATP binding IEA--
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
         
    Find genes that share ontologies with NRBP2           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NRBP2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NRBP2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NRBP2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NRBP2

    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate NRBP2:
    hsa-miR-203 hsa-miR-4328
    SwitchGear 3'UTR luciferase reporter plasmidNRBP2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NRBP2
    Predesigned siRNA for gene silencing in human, mouse, rat NRBP2

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    Addgene plasmids for NRBP2 

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NRBP2_HUMAN, Q9NSY0: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS--

    Find genes that share ontologies with NRBP2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NRBP2
    Interactions:

        Search GeneGlobe Interaction Network for NRBP2

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----
    GO:0016242negative regulation of macroautophagy IMP--
    GO:0030182neuron differentiation ISS--
    GO:0043524negative regulation of neuron apoptotic process ISS--

    Find genes that share ontologies with NRBP2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NRBP2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NRBP2 gene: 
    NM_178564.3  

    Unigene Cluster for NRBP2:

    Nuclear receptor binding protein 2
    Hs.521926  [show with all ESTs]
    Unigene Representative Sequence: BC071605
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000533093(uc010mfm.3 uc011lkt.2 uc011lks.2 uc003yzy.3)
    ENST00000529747(uc003yzv.3) ENST00000442628 ENST00000423469(uc003yzw.3 uc010mfl.3)
    ENST00000527545(uc003yzz.1) ENST00000530123 ENST00000532940 ENST00000533846
    ENST00000531729 ENST00000530347 ENST00000327830
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NRBP2 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate NRBP2:
    hsa-miR-203 hsa-miR-4328
    SwitchGear 3'UTR luciferase reporter plasmidNRBP2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NRBP2
    Predesigned siRNA for gene silencing in human, mouse, rat NRBP2
    Clone
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    GenScript: all cDNA clones in your preferred vector: NRBP2 (NM_178564)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NRBP2
    Addgene plasmids for NRBP2 
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    OriGene qSTAR qPCR primer pairs in human, mouse for NRBP2
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat NRBP2
      QuantiTect SYBR Green Assays in human, mouse, rat NRBP2
      QuantiFast Probe-based Assays in human, mouse, rat NRBP2

    Additional mRNA sequence: 

    AF318376.1 AK094017.1 AK293943.1 AK308967.1 AL137662.1 AL834530.1 AY277601.1 BC037396.1 
    BC071605.1 BC113873.1 BC114481.1 CR457350.1 

    10 DOTS entries:

    DT.91658878  DT.99998018  DT.91715977  DT.452189  DT.91930851  DT.102826133  DT.97770130  DT.91715938 
    DT.91715961  DT.91715976 

    Selected AceView cDNA sequences (see all 184):

    AI270337 BQ581932 AI628485 AL043910 AI185303 BM709377 BC071605 BQ581607 
    AI572100 BU622779 AA581126 R57939 BQ014431 CA436719 AI094905 AI262888 
    AI925077 AA339682 AA779553 AI766883 AI078182 AA470657 AL137662 BE049400 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for NRBP2 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b · 15c ^ 16 ^ 17 ^ 18a · 18b ^ 19a · 19b
    SP1:              -                                                                 -                                                           -               
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                            -               
    SP5:              -                                                                                                                                             


    ECgene alternative splicing isoforms for NRBP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NRBP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTTCTAAATG
    NRBP2 Expression
    About this image


    NRBP2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Seminiferous Tubules
     
     Bone (Muscoskeletal System)
             Chondrocytes Zeugopod Epiphyseal End
     
     Cartilage (Muscoskeletal System)
             Chondrocytes Zeugopod Epiphyseal End
    NRBP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NRBP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.521926
        Custom PCR Arrays for NRBP2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRBP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for NRBP2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nrbp25 nuclear receptor binding protein 2   --   15 (35.35 cM) 76085595 
    chicken
    (Gallus gallus)
    Aves NRBP21 nuclear receptor binding protein 2 70.11(n)
    68.13(a)
      776552  XM_001236066.3  XP_001236067.3 
    lizard
    (Anolis carolinensis)
    Reptilia NRBP26
    nuclear receptor binding protein 2
    69(a)
    1 ↔ 1
    AAWZ02037188(3405-18367)
    zebrafish
    (Danio rerio)
    Actinopterygii nrbp21 nuclear receptor binding protein 2 66.74(n)
    66.1(a)
      564177  XM_001920637.3  XP_001920672.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Madm6
    MLF1-adaptor molecule
    38(a)
    1 → many
    3R(1568214-1571789)
    worm
    (Caenorhabditis elegans)
    Secernentea hpo-116
    Protein HPO-11 (hpo-11) mRNA, complete cds
    32(a)
    1 → many
    I(7140278-7147230) WBGene00010427


    ENSEMBL Gene Tree for NRBP2 (if available)
    TreeFam Gene Tree for NRBP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NRBP2 gene
    WNK12  WNK42  WNK22  NRBP12  WNK32  
    2 SIMAP similar genes for NRBP2 using alignment to 4 protein entries:     NRBP2_HUMAN (see all proteins):
    NRBP1    WNK4

    Find genes that share paralogs with NRBP2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NRBP2 (see all 245)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs603648901,2
    C--140177744(+) TAATA-/AATA  
            
    GTACC
    1 -- us2k12Minor allele frequency- AATA:0.25NA 4
    rs1873251511,2
    C--140177819(+) CCCCCA/CCAGTG 1 -- us2k10--------
    rs1428271021,2
    --140177999(+) TTGCCC/TGGAAC 1 -- us2k10--------
    rs1167021401,2
    F--140178089(+) CCTTTC/TGCCTG 1 -- us2k11Minor allele frequency- T:0.05WA 118
    rs1181060891,2
    F--140178090(+) CTTTCG/ACCTGC 1 -- us2k11Minor allele frequency- A:0.01EA 120
    rs1918301401,2
    --140178108(+) GACTTC/TTCCCG 1 -- us2k10--------
    rs1473532291,2
    --144915432(+) ACATAC/TAGAAA 1 -- ds50010--------
    rs2006394381,2
    --144915449(+) AAACC-/AAAAAA 1 -- ds50010--------
    rs1883817851,2
    --144915472(+) TAACTC/TCAGGG 1 -- ds50010--------
    rs1928544841,2
    --144915825(+) TACTTG/TAAAAA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NRBP2 (144915755 - 144924200 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for NRBP2 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv7945n71CNV Loss21882294
    dgv7946n71CNV Loss21882294
    nsv891766CNV Loss21882294
    nsv891776CNV Loss21882294
    dgv7943n71CNV Loss21882294
    dgv7939n71CNV Loss21882294
    dgv7935n71CNV Loss21882294
    dgv7940n71CNV Loss21882294
    dgv7944n71CNV Loss21882294
    nsv466009CNV Loss19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NRBP2
    DNA2.0 Custom Variant and Variant Library Synthesis for NRBP2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615563    OMIM disorders: --

    1 disease for NRBP2:    
    About MalaCards
    medulloblastoma

    1 disease from the University of Copenhagen DISEASES database for NRBP2:
    Childhood medulloblastoma

    Find genes that share disorders with NRBP2           About GenesLikeMe


    Export disorders for NRBP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NRBP2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with NRBP2)
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    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    4. Nuclear receptor binding protein 2 is induced during neural progenitor differentiation and affects cell survival. (PubMed id 18619852)1 Larsson J....Forsberg-Nilsson K. (Mol. Cell. Neurosci. 2008)
    5. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    6. DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (Nature 2006)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. (PubMed id )2 
    9. Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise. (PubMed id 15985525)9 Mahoney D.J....Tarnopolsky M.A. (FASEB J. 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 340371 HGNC: 19339 AceView: LOC340371 Ensembl:ENSG00000185189 euGenes: HUgn340371
    ECgene: NRBP2 H-InvDB: NRBP2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NRBP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for NRBP2 gene:
    Search GeneIP for patents involving NRBP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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