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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NRBP2 Gene

protein-coding GIFtS: 45
GCID: GC08M144917

nuclear receptor binding protein 2

Explore 3 diseases affiliated with
NRBP2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Nuclear Receptor Binding Protein 2¹ ²		Pp9320¹
DKFZp434P086¹		Transformation-Related Protein 16²
TRG16²		TRG-16³
Nuclear Receptor-Binding Protein 2²		Transformation-Related Gene 16 Protein³

External Ids:	HGNC: 19339¹	Entrez Gene: 340371²	Ensembl: ENSG00000185189⁷	UniProtKB: Q9NSY0³

Export aliases for NRBP2 gene to outside databases

Previous GC identifers: GC08M144988 GC08M140168

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: NRBP2_HUMAN, Q9NSY0

Function: May regulate apoptosis of neural progenitor cells during their differentiation (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000008.10 NC_018919.1 NT_008046.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NRBP2 gene promoter:
Egr-3 Spz1 AML1a Sp1 STAT5A LCR-F1 FOXO4 ZIC2/Zic2 ATF6
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): NRBP2 promoter sequence

Search SABiosciences Chromatin IP Primers for NRBP2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NRBP2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.3 Ensembl cytogenetic band: 8q24.3 HGNC cytogenetic band: 8q24.3

NRBP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NRBP2 gene location

GeneLoc information about chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M144917: view genomic region (about GC identifiers)

Start:	144,915,755 bp from pter	End:	144,924,200 bp from pter
Size:	8,446 bases	Orientation:	minus strand

1 alternative location:

Chr8-,PATCHES 144,902,120-144,909,509

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NRBP2_HUMAN, Q9NSY0 (See protein sequence)

Recommended Name: Nuclear receptor-binding protein 2

Size: 501 amino acids; 57803 Da

Subcellular location: Cytoplasm (By similarity)

Sequence caution: Sequence=AAI13874.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact;

Sequence=CAB70864.1; Type=Miscellaneous discrepancy; Note=Wrong choice of CDS;

Secondary accessions: B4DF59 Q2HIX8 Q597G7 Q8NCX8 Q8WYS5

Alternative splicing: 4 isoforms: Q9NSY0-3 Q9NSY0-2 Q9NSY0-4 Q9NSY0-5 (No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for NRBP2: NX_Q9NSY0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NSY0

NRBP2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_848659.2

ENSEMBL proteins:

ENSP00000414055 ENSP00000431280 ENSP00000432374 ENSP00000330271

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: NRBP2 OriGene Protein Over-expression Lysate: NRBP2 OriGene Custom Protein Services for NRBP2
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	Novus Biologicals NRBP2 Proteins Novus Biologicals NRBP2 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for NRBP2

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	ISS	--

NRBP2 for ontologies About GeneDecksing

NRBP2 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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	GenScript Custom Superior Antibodies Services for NRBP2
	Novus Biologicals NRBP2 Antibodies
	Search for Antibodies for NRBP2 at Abcam
	Uscn Antibodies for NRBP2
	ThermoFisher Antibodies for NRBP2

Assay Products for NRBP2:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for NRBP2
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for NRBP2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NRBP2 for domains About GeneDecksing

2 InterPro domains/families:

IPR011009 Kinase-like_dom

IPR000719 Prot_kinase_cat_dom

Graphical View of Domain Structure for InterPro Entry Q9NSY0

ProtoNet protein and cluster: Q9NSY0

UniProtKB/Swiss-Prot: NRBP2_HUMAN, Q9NSY0

Domain: The protein kinase domain is predicted to be catalytically inactive

Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family

Similarity: Contains 1 protein kinase domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: NRBP2_HUMAN, Q9NSY0

Function: May regulate apoptosis of neural progenitor cells during their differentiation (By similarity)

miRNA Products:		OriGene 3'-UTR Clone: NRBP2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NRBP2
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate NRBP2:
		hsa-miR-203 hsa-miR-4328
		SwitchGear 3'UTR luciferase reporter plasmid: NRBP2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NRBP2 (see all 7) OriGene shRNA RFP: NRBP2 OriGene siRNA: NRBP2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NRBP2

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for NRBP2

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NRBP2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NRBP2 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: NRBP2 (NM_178564)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NRBP2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NRBP2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for NRBP2
		Search LifeMap BioReagents cell lines for NRBP2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRBP2

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	NOT nucleotide binding	NAS	--
GO:0004672	NOT protein kinase activity	NAS	--
GO:0005524	ATP binding	--	--

NRBP2 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NRBP2

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006468	NOT protein phosphorylation	NAS	--
GO:0016242	negative regulation of macroautophagy	IMP	--
GO:0030182	neuron differentiation	ISS	--
GO:0043524	negative regulation of neuron apoptotic process	ISS	--

NRBP2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NRBP2
Search CenterWatch for drugs/clinical trials and news about NRBP2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NRBP2 gene:

NM_178564.3

Unigene Cluster for NRBP2:

Nuclear receptor binding protein 2

Hs.521926 [show with all ESTs]

Unigene Representative Sequence: BC071605

11 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000533093(uc010mfm.3 uc011lkt.2 uc011lks.2 uc003yzy.3)

ENST00000529747(uc003yzv.3) ENST00000442628 ENST00000423469(uc003yzw.3 uc010mfl.3)

ENST00000527545(uc003yzz.1) ENST00000530123 ENST00000532940 ENST00000533846

ENST00000531729 ENST00000530347 ENST00000327830

miRNA Products:		OriGene 3'-UTR Clone: NRBP2 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NRBP2
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate NRBP2:
		hsa-miR-203 hsa-miR-4328
		SwitchGear 3'UTR luciferase reporter plasmid: NRBP2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NRBP2 (see all 7) OriGene shRNA RFP: NRBP2 OriGene siRNA: NRBP2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NRBP2

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NRBP2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NRBP2 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: NRBP2 (NM_178564)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NRBP2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NRBP2

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NRBP2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat NRBP2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NRBP2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NRBP2

Additional cDNA sequence:

AF318376.1 AK094017.1 AK293943.1 AK308967.1 AL137662.1 AL834530.1 AY277601.1 BC037396.1

BC071605.1 BC113873.1 BC114481.1 CR457350.1

10 DOTS entries:

DT.91658878 DT.99998018 DT.91715977 DT.452189 DT.91930851 DT.102826133 DT.97770130 DT.91715938

DT.91715961 DT.91715976

24/184 AceView cDNA sequences (see all 184):

AI376375 AA602238 AI973202 AI654590 BQ581932 NM_178564 AA411509 BE042942

AI572100 R57939 AA331578 AI937748 BE551295 AA427434 BX410189 BF115005

AA470657 AL137662 AI270337 AI766883 AI128010 AA321508 AL043910 BC037396

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for NRBP2 (see all 8) About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12a	·	12b	^	13	^	14	^	15a	·	15b	·	15c	^	16	^	17	^	18a	·	18b	^	19a	·	19b
SP1:					-																						-																				-
SP2:
SP3:
SP4:																																															-
SP5:					-

ECgene alternative splicing isoforms for NRBP2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NRBP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTCTAAATG

About this image

NRBP2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Testis

Seminiferous Tubules

Testis

Testis Cord

Testis

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See NRBP2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NRBP2

SOURCE GeneReport for Unigene cluster: Hs.521926

SABiosciences Custom PCR Arrays for NRBP2

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NRBP2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat NRBP2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NRBP2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NRBP2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRBP2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for NRBP2 gene from 8/23 species (see all 23) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Nrbp2⁵	nuclear receptor binding protein 2	--		15 (35.35 cM) 76085595
chicken (Gallus gallus)	Aves	NRBP2¹	nuclear receptor binding protein 2	79.07(n) 81.4(a)		776552 XM_001236066.2 XP_001236067.2
lizard (Anolis carolinensis)	Reptilia	NRBP2⁶ --	--	83(a) 1(a)	1 ↔ 1 possible ortholog	AAWZ02037188(3609-18357) 1(205439218-205490633)
zebrafish (Danio rerio)	Actinopterygii	nrbp2¹	nuclear receptor binding protein 2	66.81(n) 66.18(a)		564177 XM_001920637.2 XP_001920672.2
fruit fly (Drosophila melanogaster)	Insecta	Madm⁶	MLF1-adaptor molecule	38(a)	1 → many	3R(1568214-1571789)
worm (Caenorhabditis elegans)	Secernentea	hpo-11⁶	--	30(a)	1 → many	I(7140277-7147229)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT5G55560⁶ WNK3⁶ (see all 11)	putative serine/threonine-protein kinase WNK3 (see all 11)	28(a) 18(a) (see all 11)	many ↔ many many ↔ many (see all 11)	5(22506302-22507879) 3(17873012-17875220)
rice (Oryza sativa)	Liliopsida	-- -- (see all 10)	STE_PAK_Ste20_Slob_Wnk.5 - STE kinases include hom... STE_PAK_Ste20_Slob_Wnk.6 - STE kinases include hom... (see all 10)	26(a) 24(a) (see all 10)	many ↔ many many ↔ many (see all 10)	7(23676870-23678955) 12(3127501-3130910)

ENSEMBL Gene Tree for NRBP2 (if available)
TreeFam Gene Tree for NRBP2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for NRBP2 gene

WNK1² WNK4² NRBP1² WNK2² WNK3²

3 SIMAP similar genes for NRBP2 using alignment to 4 protein entries: NRBP2_HUMAN (see all proteins):

NRBP1 WNK1 WNK4

NRBP2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Clinical significance	Chr 8 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data				Transcription Related Data				Allele Frequencies
			--	--	--		--	--
rs147353229^1,2	--	144915432(+)	`ACATAC/TAGAAA`	1	--	ds500¹		0	--	--	--	--
rs200639438^1,2	--	144915449(+)	`AAACC-/AAAAAA`	1	--	ds500¹		0	--	--	--	--
rs188381785^1,2	--	144915472(+)	`TAACTC/TCAGGG`	1	--	ds500¹		0	--	--	--	--
rs192854484^1,2	--	144915825(+)	`TACTTG/TAAAAA`	1	--	ut3¹		0	--	--	--	--
rs146151179^1,2	--	144915843(+)	`TATAT-/AATTCTG AAAAGATAAAATTT`	1	--	ut3¹		0	--	--	--	--
rs184843824^1,2	--	144915942(+)	`CAGTAA/GTACAA`	1	--	ut3¹		0	--	--	--	--
rs139530595^1,2	--	144916058(+)	`GAGTTA/GGAAGG`	1	--	ut3¹		0	--	--	--	--
rs189404604^1,2	--	144916153(+)	`ATATGC/TGTTAG`	1	--	ut3¹		0	--	--	--	--
rs145148338^1,2	--	144916326(+)	`AGGAGA/GGAGAT`	1	--	ut3¹		0	--	--	--	--
rs180983709^1,2	--	144916513(+)	`GCCTTA/CGTTTA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for NRBP2 (144915755 - 144924200 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for NRBP2: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NRBP2

DNA2.0 Custom Variant and Variant Library Synthesis for NRBP2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NRBP2 for disorders About GeneDecksing

3 diseases for NRBP2: About MalaCards

childhood medulloblastoma medulloblastoma neuronitis

1 disease from the University of Copenhagen DISEASES database for NRBP2:

Childhood medulloblastoma

Export disorders for NRBP2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for NRBP2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with NRBP2)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2, 3} Ota T.... Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)^{1, 2} Wan D....Gu J. (2004)
Nuclear receptor binding protein 2 is induced during neural progenitor differentiation and affects cell survival. (PubMed id 18619852)¹ Larsson J....Forsberg-Nilsson K. (2008)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)² Nusbaum C....Lander E.S. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)
Analysis of global mRNA expression in human skeletal muscle during recovery from endurance exercise. (PubMed id 15985525)⁹ Mahoney D.J....Tarnopolsky M.A. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 340371	HGNC: 19339	AceView: LOC340371	Ensembl:ENSG00000185189	euGenes: HUgn340371
ECgene: NRBP2	H-InvDB: NRBP2

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for NRBP2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for NRBP2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for NRBP2 gene:
Search GeneIP for patents involving NRBP2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	Browse OriGene Antibodies		OriGene shRNA RFP for NRBP2
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NRBP2		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NRBP2
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NRBP2
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	GenScript Custom Purified and Recombinant Proteins Services for NRBP2		GenScript cDNA clones with any tag delivered in your preferred vector for NRBP2
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NRBP2

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ThermoFisher Antibodies for NRBP2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NRBP2

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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NRBP2 Gene

nuclear receptor binding protein 2

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NRBP2 Gene

nuclear receptor binding protein 2

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