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Aliases for NR3C1 Gene

Aliases for NR3C1 Gene

  • Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) 2 3
  • GRL 3 4 6
  • GCR 3 6
  • GR 3 4
  • Nuclear Receptor Subfamily 3, Group C, Member 1 2
  • Nuclear Receptor Subfamily 3 Group C Member 1 4
  • Glucocorticoid Nuclear Receptor Variant 1 3
  • Glucocorticoid Receptor 3
  • GCRST 3
  • GCCR 3

External Ids for NR3C1 Gene

Previous Symbols for NR3C1 Gene

  • GRL

Summaries for NR3C1 Gene

Entrez Gene Summary for NR3C1 Gene

  • This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]

GeneCards Summary for NR3C1 Gene

NR3C1 (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor)) is a Protein Coding gene. Diseases associated with NR3C1 include glucocorticoid resistance and osteochondrosis. Among its related pathways are Glucocorticoid receptor regulatory network and Circadian Clock. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and protein dimerization activity. An important paralog of this gene is AR.

UniProtKB/Swiss-Prot for NR3C1 Gene

  • Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression.

Tocris Summary for NR3C1 Gene

  • Glucocorticoid receptors (GRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid, progesterone and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by GRs is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-kappaB, AP-1 or STAT. GRs are ubiquitously expressed and mediate a vast array of physiological functions. Glucocorticoids regulate carbohydrate, protein and fat metabolism, modulate immune responses through supression of chemokine and cytokine production and have critical roles in constitutive activity of the CNS, digestive, hematopoietic, renal and reproductive systems. The human gene encoding the glucocorticoid receptor has been localized to 5q31-q32.

Gene Wiki entry for NR3C1 Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NR3C1 Gene

Genomics for NR3C1 Gene

Genomic Location for NR3C1 Gene

Start:
143,277,931 bp from pter
End:
143,733,756 bp from pter
Size:
455,826 bases
Orientation:
Minus strand

Genomic View for NR3C1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NR3C1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NR3C1 Gene

Regulatory Elements for NR3C1 Gene

Transcription factor binding sites by QIAGEN in the NR3C1 gene promoter:

Proteins for NR3C1 Gene

  • Protein details for NR3C1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P04150-GCR_HUMAN
    Recommended name:
    Glucocorticoid receptor
    Protein Accession:
    P04150
    Secondary Accessions:
    • A0ZXF9
    • B0LPG8
    • D3DQF4
    • P04151
    • Q53EP5
    • Q6N0A4

    Protein attributes for NR3C1 Gene

    Size:
    777 amino acids
    Molecular mass:
    85659 Da
    Quaternary structure:
    • Heteromultimeric cytoplasmic complex with HSP90AA1, HSPA1A/HSPA1B, and FKBP5 or another immunophilin such as PPID, STIP1, or the immunophilin homolog PPP5C. Upon ligand binding FKBP5 dissociates from the complex and FKBP4 takes its place, thereby linking the complex to dynein and mediating transport to the nucleus, where the complex dissociates. Directly interacts with UNC45A. Binds to DNA as a homodimer, and as heterodimer with NR3C2 or the retinoid X receptor. Binds STAT5A and STAT5B homodimers and heterodimers. Interacts with NRIP1, POU2F1, POU2F2 and TRIM28. Interacts with several coactivator complexes, including the SMARCA4 complex, CREBBP/EP300, TADA2L (Ada complex) and p160 coactivators such as NCOA2 and NCOA6. Interaction with BAG1 inhibits transactivation. Interacts with HEXIM1, PELP1 and TGFB1I1. Interacts with NCOA1, NCOA3, SMARCA4, SMARCC1, SMARCD1, and SMARCE1. Interacts with CLOCK, CRY1 and CRY2 in a ligand-dependent fashion. Interacts with CIART. Interacts with RWDD3. Interacts with UBE2I/UBC9 and this interaction is enhanced in the presence of RWDD3. Interacts with GRIP1 (PubMed:15769988).
    Miscellaneous:
    • Can up- or down-modulate aggregation and nuclear localization of expanded polyglutamine polypeptides derived from AR and HD through specific regulation of gene expression. Aggregation and nuclear localization of expanded polyglutamine proteins are regulated cellular processes that can be modulated by this receptor, a well-characterized transcriptional regulator
    • High constitutive expression of isoform Beta by neutrophils may provide a mechanism by which these cells escape glucocorticoid-induced cell death. Up-regulation by proinflammatory cytokines such as IL8 further enhances their survival in the presence of glucocorticoids during inflammation

    Three dimensional structures from OCA and Proteopedia for NR3C1 Gene

    Alternative splice isoforms for NR3C1 Gene

neXtProt entry for NR3C1 Gene

Proteomics data for NR3C1 Gene at MOPED

Post-translational modifications for NR3C1 Gene

  • Acetylation by CLOCK reduces its binding to glucocorticoid response elements and its transcriptional activity.
  • Increased proteasome-mediated degradation in response to glucocorticoids
  • Phosphorylated in the absence of hormone; becomes hyperphosphorylated in the presence of glucocorticoid. The Ser-203-phosphorylated form is mainly cytoplasmic, and the Ser-211-phosphorylated form is nuclear. Transcriptional activity correlates with the amount of phosphorylation at Ser-211. May be dephosphorylated by PPP5C, attenuates NR3C1 action.
  • Sumoylated; this reduces transcription transactivation.
  • Ubiquitinated; restricts glucocorticoid-mediated transcriptional signaling.
  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys419

No data available for DME Specific Peptides for NR3C1 Gene

Domains for NR3C1 Gene

Gene Families for NR3C1 Gene

HGNC:
  • NR :Nuclear hormone receptors
IUPHAR :

UniProtKB/Swiss-Prot:

GCR_HUMAN
Domain:
  • Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.:
    • P04150
  • Contains 1 nuclear receptor DNA-binding domain.:
    • P04150
Family:
  • Belongs to the nuclear hormone receptor family. NR3 subfamily.:
    • P04150
genes like me logo Genes that share domains with NR3C1: view

Function for NR3C1 Gene

Molecular function for NR3C1 Gene

GENATLAS Biochemistry: nuclear recptor subafamily 3,group C,member 1,steroid/thyroid hormone receptor superfamily,interacting with tissue-specific transcriptional activators required for receptor actin (see HNFS)
UniProtKB/Swiss-Prot Function: Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression.

Gene Ontology (GO) - Molecular Function for NR3C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IDA 16728402
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IDA 16728402
GO:0003677 DNA binding --
GO:0003700 sequence-specific DNA binding transcription factor activity IDA 15769988
GO:0003707 steroid hormone receptor activity --
genes like me logo Genes that share ontologies with NR3C1: view
genes like me logo Genes that share phenotypes with NR3C1: view

Animal Models for NR3C1 Gene

MGI Knock Outs for NR3C1:

Transcription Factor Targeting for NR3C1 Gene

Selected GeneGlobe predicted Target genes for NR3C1
Targeting motifs for NR3C1 Gene
HOMER Transcription Factor Regulatory Elements motif NR3C1
  • Consensus sequence: NAGAACAGNCTGTTCT Submotif: IR3 Cell Type: A549 GeoId: GSE32465

No data available for Enzyme Numbers (IUBMB) for NR3C1 Gene

Localization for NR3C1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NR3C1 Gene

Cytoplasm. Mitochondrion. Nucleus. Note=Cytoplasmic in the absence of ligand, nuclear after ligand-binding.
Isoform Beta: Nucleus. Note=Localized largely in the nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for NR3C1 Gene COMPARTMENTS Subcellular localization image for NR3C1 gene
Compartment Confidence
mitochondrion 5
nucleus 5
cytosol 3
cytoskeleton 2
extracellular 2
peroxisome 2
plasma membrane 2
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for NR3C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IDA 15769988
GO:0005654 nucleoplasm TAS --
GO:0005737 cytoplasm IDA --
GO:0005759 mitochondrial matrix TAS 10887960
genes like me logo Genes that share ontologies with NR3C1: view

Pathways for NR3C1 Gene

genes like me logo Genes that share pathways with NR3C1: view

Gene Ontology (GO) - Biological Process for NR3C1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006111 regulation of gluconeogenesis IEA --
GO:0006351 transcription, DNA-templated TAS 10887960
GO:0006355 regulation of transcription, DNA-templated IDA 19141540
GO:0006366 transcription from RNA polymerase II promoter TAS 8621628
GO:0006367 transcription initiation from RNA polymerase II promoter TAS --
genes like me logo Genes that share ontologies with NR3C1: view

Compounds for NR3C1 Gene

(5) Tocris Compounds for NR3C1 Gene

Compound Action Cas Number
Corticosterone Endogenous glucocorticoid [50-22-6]
Fluticasone propionate Selective high affinity glucocorticoid agonist [80474-14-2]
GSK 9027 Glucocorticoid receptor agonist [1229096-88-1]
Hydrocortisone Adrenal glucocorticoid; immunosuppressant [50-23-7]
Mometasone furoate Synthetic corticosteroid; anti-inflammatory agent [83919-23-7]

(4) HMDB Compounds for NR3C1 Gene

Compound Synonyms Cas Number PubMed IDs
Aldosterone
  • (+)-Aldosterone
52-39-1
Cortexolone
  • 11-Deoxy-17-hydroxycorticosterone
152-58-9
Cortisol
  • 11-Hydrocortisone
50-23-7
Deoxycorticosterone
  • 11-Dehydroxycorticosterone
64-85-7

(40) Drugbank Compounds for NR3C1 Gene

Compound Synonyms Cas Number Type Actions PubMed IDs
Alclometasone
66734-13-2 target agonist
Amcinonide
51022-69-6 target agonist
Beclometasone dipropionate
  • beclometasone 17,21-dipropionate
5534-09-8 target agonist
Betamethasone
378-44-9 target agonist
Budesonide
51333-22-3 target antagonist

(11) IUPHAR Ligand for NR3C1 Gene

Ligand Type Action Affinity Pubmed IDs
mifepristone Antagonist Antagonist 9.4
dexamethasone Agonist Agonist 9
triamcinolone acetonide Agonist Agonist 8.2
cortisol Agonist Agonist 8
prednisolone Agonist Agonist 7.8
triamcinolone Agonist Agonist 7.7
deoxycorticosterone Agonist Agonist 7.2
RU28362 Agonist Agonist
[3H]dexamethasone Agonist Agonist
onapristone Antagonist Antagonist
ZK112993 Antagonist Antagonist

(120) Novoseek inferred chemical compound relationships for NR3C1 Gene

Compound -log(P) Hits PubMed IDs
dexamethasone 91.8 251
mifepristone 91.4 139
steroid 86 160
11beta-hydroxysteroid 85.6 56
cortisone 78.3 23
genes like me logo Genes that share compounds with NR3C1: view

Transcripts for NR3C1 Gene

Unigene Clusters for NR3C1 Gene

Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for NR3C1 Gene

No ASD Table

Relevant External Links for NR3C1 Gene

GeneLoc Exon Structure for
NR3C1
ECgene alternative splicing isoforms for
NR3C1

Expression for NR3C1 Gene

mRNA expression in normal human tissues for NR3C1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for NR3C1 Gene

SOURCE GeneReport for Unigene cluster for NR3C1 Gene Hs.122926

mRNA Expression by UniProt/SwissProt for NR3C1 Gene

P04150-GCR_HUMAN
Tissue specificity: Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart.
genes like me logo Genes that share expressions with NR3C1: view

Orthologs for NR3C1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for NR3C1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia NR3C1 36
  • 99.7 (n)
  • 99.49 (a)
NR3C1 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia GR-A 37
  • 94 (a)
OneToOne
NR3C1 36
  • 91.62 (n)
  • 94.33 (a)
dog
(Canis familiaris)
Mammalia NR3C1 36
  • 91.54 (n)
  • 93.43 (a)
NR3C1 37
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Nr3c1 36
  • 89.58 (n)
  • 90.7 (a)
Nr3c1 16
Nr3c1 37
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia NR3C1 37
  • 83 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia NR3C1 37
  • 82 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Nr3c1 36
  • 89.15 (n)
  • 91.09 (a)
chicken
(Gallus gallus)
Aves NR3C1 36
  • 74.04 (n)
  • 75.55 (a)
NR3C1 37
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia NR3C1 37
  • 75 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia xGR 36
tropical clawed frog
(Silurana tropicalis)
Amphibia nr3c1 36
  • 69.96 (n)
  • 67.34 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.11855 36
zebrafish
(Danio rerio)
Actinopterygii nr3c1 36
  • 58.15 (n)
  • 54.21 (a)
nr3c1 37
  • 49 (a)
OneToOne
Species with no ortholog for NR3C1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for NR3C1 Gene

ENSEMBL:
Gene Tree for NR3C1 (if available)
TreeFam:
Gene Tree for NR3C1 (if available)

Paralogs for NR3C1 Gene

Paralogs for NR3C1 Gene

Pseudogenes.org Pseudogenes for NR3C1 Gene

genes like me logo Genes that share paralogs with NR3C1: view

Variants for NR3C1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for NR3C1 Gene

P04150-GCR_HUMAN
Carriers of the 22-Glu-Lys-23 allele are relatively more resistant to the effects of GCs with respect to the sensitivity of the adrenal feedback mechanism than non-carriers, resulting in a better metabolic health profile. Carriers have a better survival than non-carriers, as well as lower serum CRP levels. The 22-Glu-Lys-23 polymorphism is associated with a sex-specific, beneficial body composition at young-adult age, as well as greater muscle strength in males

Sequence variations from dbSNP and Humsavar for NR3C1 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs6187 -- 143,280,183(-) GTAGG(G/T)GTCAA utr-variant-3-prime, intron-variant
rs6188 -- 143,300,779(-) TATTT(G/T)TTTAA intron-variant
rs6189 Pathogenic 143,400,774(-) CAGGA(A/G)AGGGG synonymous-codon, reference, utr-variant-5-prime
rs6190 - 143,400,772(-) GGAGA(A/G)GGGAG missense, reference, utr-variant-5-prime
rs6191 -- 143,278,591(-) TTTTT(G/T)TGTGT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for NR3C1 Gene

Variant ID Type Subtype PubMed ID
esv33748 CNV Loss 17666407
nsv5041 CNV Loss 18451855
esv2730855 CNV Deletion 23290073
esv2730856 CNV Deletion 23290073
esv1954637 CNV Deletion 18987734
esv2730857 CNV Deletion 23290073
nsv328009 CNV Loss 16902084
nsv328818 CNV Loss 16902084
esv1001228 CNV Deletion 20482838
esv2730858 CNV Deletion 23290073
esv1765773 CNV Deletion 17803354
nsv327674 CNV Loss 16902084
nsv327858 CNV Loss 16902084
esv2666615 CNV Deletion 23128226
nsv882994 CNV Loss 21882294
esv1786342 CNV Insertion 17803354

Relevant External Links for NR3C1 Gene

HapMap Linkage Disequilibrium report
NR3C1
Human Gene Mutation Database (HGMD)
NR3C1
Locus Specific Mutation Databases (LSDB)
NR3C1

Disorders for NR3C1 Gene

UniProtKB/Swiss-Prot

GCR_HUMAN
  • Glucocorticoid resistance, generalized (GCCR) [MIM:615962]: An autosomal dominant disease characterized by increased plasma cortisol concentration and high urinary free cortisol, resistance to adrenal suppression by dexamethasone, and the absence of Cushing syndrome typical signs. Clinical features include hypoglycemia, hypertension, metabolic alkalosis, chronic fatigue and profound anxiety. {ECO:0000269 PubMed:15769988, ECO:0000269 PubMed:17635946}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Glucocorticoid resistance (GCRES) [MIM:138040]: Hypertensive, hyperandrogenic disorder characterized by increased serum cortisol concentrations. Inheritance is autosomal dominant. {ECO:0000269 PubMed:11589680, ECO:0000269 PubMed:12050230, ECO:0000269 PubMed:7683692}. Note=The disease is caused by mutations affecting the gene represented in this entry.

(6) University of Copenhagen DISEASES for NR3C1 Gene

(91) Novoseek inferred disease relationships for NR3C1 Gene

Disease -log(P) Hits PubMed IDs
cushing syndrome 69.7 14
mammary tumor 63.9 30
hypercortisolism 61.5 4
hypercortisolemia 61.2 5
asthma 55.9 88

Relevant External Links for NR3C1

Genetic Association Database (GAD)
NR3C1
Human Genome Epidemiology (HuGE) Navigator
NR3C1
genes like me logo Genes that share disorders with NR3C1: view

Publications for NR3C1 Gene

  1. The N363S polymorphism of the glucocorticoid receptor: potential contribution to central obesity in men and lack of association with other risk factors for coronary heart disease and diabetes mellitus. (PMID: 11344238) Dobson M.G. … Weaver J.U. (J. Clin. Endocrinol. Metab. 2001) 3 4 23 49
  2. Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul study. (PMID: 20371666) Otte C. … Whooley M.A. (J. Clin. Endocrinol. Metab. 2010) 3 23 25 49
  3. Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor. (PMID: 10639135) Diamond M.I. … Yamamoto K.R. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 4 23
  4. Proteasome-mediated glucocorticoid receptor degradation restricts transcriptional signaling by glucocorticoids. (PMID: 11555652) Wallace A.D. … Cidlowski J.A. (J. Biol. Chem. 2001) 3 4 23
  5. A variant of the glucocorticoid receptor gene is not associated with adrenal androgen excess in women with polycystic ovary syndrome. (PMID: 11119758) Kahsar-Miller M. … Witchel S.F. (Fertil. Steril. 2000) 3 23 49

Products for NR3C1 Gene

  • Addgene plasmids for NR3C1

Sources for NR3C1 Gene

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