Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



NR2C2AP Gene

protein-coding   GIFtS: 46
GCID: GC19M019312

Nuclear Receptor 2C2-Associated Protein

  See NR2C2AP-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Nuclear Receptor 2C2-Associated Protein1 2
TR4 Orphan Receptor Associated Protein TRA161 2
TRA162 3
TR4 Orphan Receptor-Associated 16 KDa Protein2 3
Repressor For TR4 Transactivation2

External Ids:    HGNC: 307631   Entrez Gene: 1263822   Ensembl: ENSG000001841627   OMIM: 6087195   UniProtKB: Q86WQ03   
ORGUL members:         

Export aliases for NR2C2AP gene to outside databases

Previous GC identifers: GC19M019174 GC19M018875


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for NR2C2AP Gene:
NR2C2AP (nuclear receptor 2C2-associated protein) is a protein-coding gene. Diseases associated with NR2C2AP include non-small cell lung carcinoma.

UniProtKB/Swiss-Prot: NR2CA_HUMAN, Q86WQ0
Function: May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4
and the TR4-response element in target genes




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the NR2C2AP gene promoter:
         SRF   Max1   NRSF form 1   POU3F2   NRSF form 2   c-Ets-1   Roaz   AREB6   Pax-4a   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidNR2C2AP promoter sequence
   Search Chromatin IP Primers for NR2C2AP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NR2C2AP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.11   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13.11

NR2C2AP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NR2C2AP gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M019312:  view genomic region     (about GC identifiers)

Start:
19,312,224 bp from pter      End:
19,314,238 bp from pter
Size:
2,015 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: NR2CA_HUMAN, Q86WQ0 (See protein sequence)
Recommended Name: Nuclear receptor 2C2-associated protein  
Size: 139 amino acids; 15876 Da
Subunit: Interacts with NR2C2/TR4
Secondary accessions: A6NGP7

Explore the universe of human proteins at neXtProt for NR2C2AP: NX_Q86WQ0

Explore proteomics data for NR2C2AP at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See NR2C2AP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_795361.1  
    ENSEMBL proteins: 
     ENSP00000402756   ENSP00000332823   ENSP00000438092   ENSP00000475559   ENSP00000476087  
    Reactome Protein details: Q86WQ0

    NR2C2AP Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for NR2C2AP
    OriGene Protein Over-expression Lysate for NR2C2AP
    OriGene MassSpec for NR2C2AP
    OriGene Custom Protein Services for NR2C2AP
    GenScript Custom Purified and Recombinant Proteins Services for NR2C2AP
    Novus Biologicals NR2C2AP Proteins
    Novus Biologicals NR2C2AP Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for NR2C2AP

     
    Search eBioscience for Proteins for NR2C2AP 

     
    antibodies-online proteins for NR2C2AP (5 products) 

     
    antibodies-online peptides for NR2C2AP

    NR2C2AP Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NR2C2AP
    Novus Biologicals NR2C2AP Antibodies
    Abcam antibodies for NR2C2AP
    Cloud-Clone Corp. Antibodies for NR2C2AP
    Search ThermoFisher Antibodies for NR2C2AP
    antibodies-online antibodies for NR2C2AP (39 products) 

    NR2C2AP Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for NR2C2AP
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NR2C2AP
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for NR2C2AP
    Cloud-Clone Corp. CLIAs for NR2C2AP
    Search eBioscience for ELISAs for NR2C2AP 
    antibodies-online kits for NR2C2AP (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR000421 Coagulation_fac_5/8-C_type_dom
     IPR008979 Galactose-bd-like

    Graphical View of Domain Structure for InterPro Entry Q86WQ0

    ProtoNet protein and cluster: Q86WQ0

    UniProtKB/Swiss-Prot: NR2CA_HUMAN, Q86WQ0
    Similarity: Belongs to the NR2C2AP family


    Find genes that share domains with NR2C2AP           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NR2CA_HUMAN, Q86WQ0
    Function: May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4
    and the TR4-response element in target genes

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with NR2C2AP           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for NR2C2AP

    miRNA
    Products:
        
    miRTarBase miRNAs that target NR2C2AP:
    hsa-mir-93-5p (MIRT027991), hsa-mir-33a-5p (MIRT028208), hsa-mir-221-3p (MIRT024142), hsa-mir-130b-3p (MIRT020167)

    Block miRNA regulation of human, mouse, rat NR2C2AP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NR2C2AP (see all 13):
    hsa-miR-1266 hsa-miR-4254 hsa-miR-765 hsa-miR-516b* hsa-miR-3914 hsa-miR-218 hsa-miR-3125 hsa-miR-3916
    SwitchGear 3'UTR luciferase reporter plasmidNR2C2AP 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for NR2C2AP
    Predesigned siRNA for gene silencing in human, mouse, rat NR2C2AP

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for NR2C2AP

    Clone
    Products:
         
    OriGene clones in human, mouse for NR2C2AP (see all 8)
    OriGene ORF clones in mouse, rat for NR2C2AP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NR2C2AP (NM_176880)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NR2C2AP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NR2C2AP

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for NR2C2AP
    Browse ESI BIO Cell Lines and PureStem Progenitors for NR2C2AP 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NR2C2AP


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    NR2CA_HUMAN, Q86WQ0: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    mitochondrion2
    cytosol1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm TAS--

    Find genes that share ontologies with NR2C2AP           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for NR2C2AP About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40
    2Nuclear Receptor transcription pathway
    Nuclear Receptor transcription pathway0.67


    Find genes that share SuperPaths with NR2C2AP           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for NR2C2AP
        Nuclear Receptor transcription pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for NR2C2AP
    Interactions:

        Search GeneGlobe Interaction Network for NR2C2AP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for NR2C2AP (Q86WQ03 ENSP000003328234) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NR2C2P491163, ENSP000003204474I2D: score=2 STRING: ENSP00000320447
    NR1H2ENSP000002537274STRING: ENSP00000253727
    NR2C1ENSP000003332754STRING: ENSP00000333275
    RARGENSP000003326954STRING: ENSP00000332695
    ESR1ENSP000002062494STRING: ENSP00000206249
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006367transcription initiation from RNA polymerase II promoter TAS--
    GO:0007155cell adhesion IEA--
    GO:0010467gene expression TAS--

    Find genes that share ontologies with NR2C2AP           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NR2C2AP (NR2CA)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for NR2C2AP gene: 
    NM_176880.4  

    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000420605(uc010xqq.1) ENST00000331552(uc002nlx.3) ENST00000537399
    ENST00000544883 ENST00000539693 ENST00000538165 ENST00000539678
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat NR2C2AP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NR2C2AP (see all 13):
    hsa-miR-1266 hsa-miR-4254 hsa-miR-765 hsa-miR-516b* hsa-miR-3914 hsa-miR-218 hsa-miR-3125 hsa-miR-3916
    SwitchGear 3'UTR luciferase reporter plasmidNR2C2AP 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for NR2C2AP
    Predesigned siRNA for gene silencing in human, mouse, rat NR2C2AP
    Clone
    Products:
         
    OriGene clones in human, mouse for NR2C2AP (see all 8)
    OriGene ORF clones in mouse, rat for NR2C2AP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: NR2C2AP (NM_176880)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NR2C2AP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NR2C2AP
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for NR2C2AP
    OriGene qSTAR qPCR primer pairs in human, mouse for NR2C2AP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NR2C2AP
      QuantiTect SYBR Green Assays in human, mouse, rat NR2C2AP
      QuantiFast Probe-based Assays in human, mouse, rat NR2C2AP

    Selected AceView cDNA sequences (see all 116):

    AI805698 CA422800 AA311632 BU689849 CF528510 BF514097 BI824739 AA378667 
    BU189792 AI280295 BM793317 AA974321 AI283704 AI375221 BI829387 AA515388 
    BG676237 BI752134 AI270772 CB528991 BG681140 AI886590 BE275344 AI281810 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for NR2C2AP    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c
    SP1:                          -                     
    SP2:                                                
    SP3:                          -                     
    SP4:                          -                     


    ECgene alternative splicing isoforms for NR2C2AP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    NR2C2AP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCCACTCTT
    NR2C2AP Expression
    About this image

    NR2C2AP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NR2C2AP Protein Expression

    UniProtKB/Swiss-Prot: NR2CA_HUMAN, Q86WQ0
    Tissue specificity: Expressed in all tissues examined, with highest expression in heart, skeletal muscle and
    pancreas

        Custom PCR Arrays for NR2C2AP
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for NR2C2AP
    OriGene qSTAR qPCR primer pairs in human, mouse for NR2C2AP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NR2C2AP
    QuantiTect SYBR Green Assays in human, mouse, rat NR2C2AP
    QuantiFast Probe-based Assays in human, mouse, rat NR2C2AP
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NR2C2AP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for NR2C2AP gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nr2c2ap1 , 5 nuclear receptor 2C2-associated protein1, 5 83.21(n)1
    82.73(a)1
      8 (34.15 cM)5
    756921  NM_001025586.21  NP_001020757.11 
     701313335 
    chicken
    (Gallus gallus)
    Aves NR2C2AP1 nuclear receptor 2C2-associated protein 66.67(n)
    67.01(a)
      100858401  XM_004948889.1  XP_004948946.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nr2c2ap1 nuclear receptor 2C2-associated protein 61.35(n)
    63.04(a)
      724051  NM_001045327.2  NP_001038792.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG342131 CG34213 51.37(n)
    45.08(a)
      5740468  NM_001103969.3  NP_001097439.2 


    ENSEMBL Gene Tree for NR2C2AP (if available)
    TreeFam Gene Tree for NR2C2AP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for NR2C2AP (see all 71)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1893164931,2
    C--19313199(+) AGTGCC/TCTGTG 2 S G mis10--------
    rs1472077441,2
    C,F--19313294(+) GCCCCG/AGCGAC 2 /R /W mis11Minor allele frequency- A:0.00NA 4534
    rs3757170101,2
    C--19313342(+) GACACA/GATGAG 2 R C mis10--------
    rs1512222781,2
    C--19313391(+) TGGAAA/GCAGAC 1 -- int10--------
    rs1926907221,2
    C--19313400(+) ACAGGA/GAAACT 1 -- int10--------
    rs1393643391,2
    --19313475(+) ATGGAC/GGGGAA 1 -- int10--------
    rs2007303211,2
    C--19313585(+) GGTCGA/GGGGAG 1 -- int10--------
    rs18590561,2
    C,F,H--19313586(+) GTCGAG/AGGAGG 1 -- int120Minor allele frequency- A:0.06MN NS EA NA CSA WA EU 3617
    rs2001426451,2
    C--19313801(+) AGGGCC/TTCGCC 1 -- int11Minor allele frequency- T:0.00EU 1323
    rs81106341,2
    C,F--19313803(+) GGCCTC/TGCCAC 1 -- int11Minor allele frequency- T:0.00EU 1323

    HapMap Linkage Disequilibrium report for NR2C2AP (19312224 - 19314238 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for NR2C2AP:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv911304CNV Loss21882294
    nsv833779CNV Loss17160897
    nsv911305CNV Loss21882294
    nsv911303CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing NR2C2AP
    DNA2.0 Custom Variant and Variant Library Synthesis for NR2C2AP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 608719    OMIM disorders: --

    1 disease for NR2C2AP:    
    About MalaCards
    non-small cell lung carcinoma


    Find genes that share disorders with NR2C2AP           About GenesLikeMe


    Export disorders for NR2C2AP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for NR2C2AP gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with NR2C2AP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel testicular orphan receptor-4 (TR4)- associated protein as repressor for the selective suppression of TR4- mediated transactivation. (PubMed id 12486131)1, 2, 3, 9 Yang Y.... Chang C. (J. Biol. Chem. 2003)
    2. Testicular orphan nuclear receptor 4-associated protein 16 promotes non-small cell lung carcinoma by activating estrogen receptor I^ and blocking testicular orphan nuclear receptorA 2. (PubMed id 23129017)1 Fang F....Yang Y. (Oncol. Rep. 2013)
    3. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PubMed id 23824909)1 Chen Y....Ge F. (amp 2013)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. A whole genome screen for HIV restriction factors. (PubMed id 22082156)1 Liu L....McKnight A. (Retrovirology 2011)
    7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    8. Transactivation of the proximal promoter of human oxytocin gene by TR4 orphan receptor. (PubMed id 17054912)1 Wang C.P....Lee H.J. (Biochem. Biophys. Res. Commun. 2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Modulation of the retinoic acid-induced cell apoptosis and differentiation by the human TR4 orphan nuclear receptor. (PubMed id 15381082)1 Lee Y.F....Chang C. (Biochem. Biophys. Res. Commun. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 126382 HGNC: 30763 AceView: TRA16 Ensembl:ENSG00000184162 euGenes: HUgn126382
    ECgene: NR2C2AP H-InvDB: NR2C2AP

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for NR2C2AP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for NR2C2AP gene:
    Search GeneIP for patents involving NR2C2AP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for NR2C2AP  
     OriGene qPCR primer pairs and template standards for NR2C2AP   OriGene Protein Over-expression Lysate for NR2C2AP  
     OriGene MassSpec for NR2C2AP   OriGene clones in human, mouse for NR2C2AP  
     OriGene qSTAR qPCR primer pairs in human, mouse for NR2C2AP   OriGene Purified Protein for NR2C2AP  
     OriGene ORF clones in mouse, rat for NR2C2AP   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NR2C2AP   OriGene Custom Protein Services for NR2C2AP  

     
     
     Block miRNA regulation of human, mouse, rat NR2C2AP using miScript Target Protectors SeqTarget long-range PCR primers for resequencing NR2C2AP
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NR2C2AP Predesigned siRNA for gene silencing in human, mouse, rat NR2C2AP
     QuantiFast Probe-based Assays in human, mouse, rat NR2C2AP QuantiTect SYBR Green Assays in human, mouse, rat NR2C2AP
     Custom PCR Arrays for NR2C2AP Search Chromatin IP Primers for NR2C2AP
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat NR2C2AP  Search GeneGlobe Interaction Network for NR2C2AP
     Regulatory tfbs in NR2C2AP promoter
     GenScript Custom Purified and Recombinant Proteins Services for NR2C2AP GenScript cDNA clones with any tag delivered in your preferred vector for NR2C2AP
     GenScript Custom Assay Services for NR2C2AP GenScript Custom overexpressing Cell Line Services for NR2C2AP
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for NR2C2AP (NR2CA)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     NR2C2AP antibodies
     NR2C2AP proteins
     NR2C2AP lysates
     Antibodies for NR2C2AP
     See all of Abcam's Antibodies, Kits and Proteins for NR2C2AP
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for NR2C2AP
     Antibodies for NR2C2AP
     ELISAs for NR2C2AP
     CLIAs for NR2C2AP



     Browse ESI BIO Cell Lines and PureStem Progenitors for NR2C2AP
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NR2C2AP
     SwitchGear 3'UTR luciferase reporter plasmids for NR2C2AP
     SwitchGear Promoter luciferase reporter plasmids for NR2C2AP
     Search ThermoFisher Antibodies for NR2C2AP
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NR2C2AP
     Browse compounds at ApexBio
     Search Addgene for plasmids for NR2C2AP
      Search eBioscience for proteins for NR2C2AP
      Search eBioscience for elisas for NR2C2AP
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for NR2C2AP
     antibodies-online antibodies for NR2C2AP (39 products)
     antibodies-online kits for NR2C2AP (6 products)
     antibodies-online peptides for NR2C2AP
     antibodies-online proteins for NR2C2AP (5 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      NR2C2AP gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4