Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

NR1I3 Gene

protein-coding   GIFtS: 63
GCID: GC01M161199

nuclear receptor subfamily 1, group I, member 3
 Explore 55 diseases affiliated with
NR1I3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for NR1I3    

Aliases
for NR1I3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Nuclear Receptor Subfamily 1, Group I, Member 31 2     Constitutive Active Receptor2
CAR1 2 3     Constitutive Androstane Nuclear Receptor Variant 22
CAR11 2     Constitutive Androstane Nuclear Receptor Variant 32
MB671 2     Constitutive Androstane Nuclear Receptor Variant 42
Constitutive Activator Of Retinoid Response2 3     Constitutive Androstane Nuclear Receptor Variant 52
Constitutive Active Response2 3     Nuclear Receptor Subfamily 1 Group I Member 32
Constitutive Androstane Receptor2 3     Orphan Nuclear Hormone Receptor2
Orphan Nuclear Receptor MB672 3     

External Ids:    HGNC: 79691   Entrez Gene: 99702   Ensembl: ENSG000001432577   OMIM: 6038815   UniProtKB: Q149943   

Export aliases for NR1I3 gene to outside databases

Previous GC identifers: GC01M158910 GC01M156931 GC01M157978 GC01M158416 GC01M158012 GC01M159466 GC01M132556


Summaries
for NR1I3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for NR1I3:
This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic
metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the
transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family
members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of
ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein
to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety
of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different
isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: NR1I3_HUMAN, Q14994
Function: Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid
receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of
the human CYP2B6 gene and the CYP3A4 xenobiotic response element

summary for NR1I3:
Vitamin D receptors (VDRs) are members of the NR1I family, which also includes pregnane X (PXR) and
constitutive androstane (CAR) receptors, that form heterodimers with members of the retinoid X receptor
family. VDR is expressed in the intestine, thyroid and kidney. VDRs repress expression of 1?-hydroxylase
(the proximal activator of 1,25(OH)2D3) and induce expression of the 1,25(OH)2D3 inactivating enzyme CYP24.
Also, it has recently been identified as an additional bile acid receptor alongside FXR and may function to
protect gut against the toxic and carcinogenic effects of these endobiotics. Inherited mutations in the VDR
gene leads to rickets, which is characterized by muscle weakness, growth retardation, bone deformity and
secondary hyperparathyroidism. The human gene encoding the vitamin D receptor has been localized to
chromosome 12q12-q14.

Gene Wiki entry for NR1I3 (Constitutive androstane receptor)


Genomic Views
for NR1I3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the NR1I3 gene promoter:
         AP-1   ATF-2   MEF-2   CRE-BP1   PPAR-alpha   CREB   MEF-2A   PPAR-gamma1   PPAR-gamma2   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NR1I3 promoter sequence
   Search SABiosciences Chromatin IP Primers for NR1I3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NR1I3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q23.3   Ensembl cytogenetic band:  1q23.3   HGNC cytogenetic band: 1q23.3

NR1I3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NR1I3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M161199:  view genomic region     (about GC identifiers)

Start:
 161,199,456 bp from pter      End:
 161,208,092 bp from pter
Size:
 8,637 bases      Orientation:
 minus strand

Proteins
for NR1I3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NR1I3_HUMAN, Q14994 (See protein sequence)
Recommended Name: Nuclear receptor subfamily 1 group I member 3  
Size: 352 amino acids; 39942 Da
Subunit: Interacts with ECT2 (By similarity). Heterodimer of NR1I3 and RXR. Interacts with PSMC4. Directly interacts
with DNAJC7. The DNAJC7-NR1I3 complex may also include HSP90 (By similarity)
Subcellular location: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Recruited to the cytoplasm by DNAJC7 (By
similarity)
2 PDB 3D structures from and Proteopedia for NR1I3:
1XV9 (3D)        1XVP (3D)    
Secondary accessions: E9PGH6 E9PH10 E9PHN4 F1D8Q0 F1D8Q1 Q0VAC9 Q4U0F0 Q5VTW5 Q5VTW6 Q6GZ68 Q6GZ77
Q6GZ78 Q6GZ83 Q6GZ84 Q6GZ85 Q6GZ87
Alternative splicing: 11 isoforms:  Q14994-1   Q14994-2   Q14994-3   Q14994-4   Q14994-5   Q14994-6   Q14994-7   Q14994-8   
Q14994-9   Q14994-10   Q14994-11   

Explore the universe of human proteins at neXtProt for NR1I3: NX_Q14994

Post-translational modifications:

  • Phosphorylated at Thr-38 by PKC, dephosphorylation of Thr-38 is required for nuclear translocation and activation1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q14994

    • NR1I3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (15 alternative transcripts): 
    NP_001070937.1  NP_001070938.1  NP_001070939.1  NP_001070940.1  NP_001070941.1  NP_001070942.1  NP_001070943.1  NP_001070944.1  
    NP_001070945.1  NP_001070946.1  NP_001070947.1  NP_001070948.1  NP_001070949.1  NP_001070950.1  NP_005113.1  

    ENSEMBL proteins: 
     ENSP00000425417   ENSP00000356962   ENSP00000407446   ENSP00000406493   ENSP00000399361  
     ENSP00000412672   ENSP00000424934   ENSP00000423666   ENSP00000356961   ENSP00000424834  
     ENSP00000422982   ENSP00000424345   ENSP00000427175   ENSP00000421374   ENSP00000423007  
     ENSP00000425607   ENSP00000356960   ENSP00000426016   ENSP00000421588   ENSP00000425900  
     ENSP00000426292   ENSP00000427600   ENSP00000356963   ENSP00000356965   ENSP00000356958  
     ENSP00000423089   ENSP00000427034   ENSP00000356959  
    Reactome Protein details: Q14994
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate (see all 24): NR1I3
    OriGene Custom Protein Services for NR1I3 
    GenScript Custom Purified and Recombinant Proteins Services for NR1I3
    Novus Biologicals NR1I3 Proteins
    Novus Biologicals NR1I3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for NR1I3

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0005654nucleoplasm TAS--
    GO:0005737cytoplasm ISS--
    GO:0005829cytosol ----
    GO:0005856cytoskeleton IEA--


    NR1I3 for ontologies           About GeneDecksing



    NR1I3 Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of NR1I3
    R&D Systems Antibodies for NR1I3 (CAR/NR1I3)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for NR1I3 
    GenScript Custom Superior Antibodies Services for NR1I3
    Novus Biologicals NR1I3 Antibodies
    Search for Antibodies for NR1I3 at Abcam  
    Uscn Antibodies for NR1I3
    Search ThermoFisher Antibodies for NR1I3

    Assay Products for NR1I3: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for NR1I3
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for NR1I3

    Protein Domains /
    Families
    for NR1I3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    NR1I3 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR013088 Znf_NHR/GATA
     IPR008946 Nucl_hormone_rcpt_ligand-bd
     IPR000536 Nucl_hrmn_rcpt_lig-bd_core
     IPR001628 Znf_hrmn_rcpt
     IPR001723 Str_hrmn_rcpt

    Graphical View of Domain Structure for InterPro Entry Q14994

    ProtoNet protein and cluster: Q14994

    2 Blocks protein families:
    IPB000324 Vitamin D receptor signature
    IPB001723 Steroid hormone receptor signature


    UniProtKB/Swiss-Prot: NR1I3_HUMAN, Q14994
    Domain: Composed by a short N-terminal domain followed by the DNA binding, hinge, and ligand binding/dimerization
    domains
    Similarity: Belongs to the nuclear hormone receptor family. NR1 subfamily
    Similarity: Contains 1 nuclear receptor DNA-binding domain


    Function
    for NR1I3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NR1I3_HUMAN, Q14994
    Function: Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid
    receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of
    the human CYP2B6 gene and the CYP3A4 xenobiotic response element
    Induction: By dexamethasone

         Genatlas biochemistry entry for NR1I3:
    nuclear receptor subfamily 1,group I,member 3,putatively heterodimerizing with RXR(s),expressed as several isoforms

    miRNA
    Products:            		 OriGene 3'-UTR Clone (see all 8): NR1I3
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NR1I3
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate NR1I3
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NR1I3 (see all 7)
    OriGene shRNA RFP: NR1I3
    OriGene siRNA: NR1I3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NR1I3

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for NR1I3

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NR1I3 (see first 1)
    NM_001077469 (human cat#: RC216643)  NM_001077470 (human cat#: RC213288)  NM_001077471 (human cat#: RC216702)  
    NM_001077472 (human cat#: RC216757)  NM_001077473 (human cat#: RC213453)  NM_001077474 (human cat#: RC216817)  
    NM_001077475 (human cat#: RC216880)  NM_001077476 (human cat#: RC213613)  NM_001077477 (human cat#: RC216922)  
    NM_001077478 (human cat#: RC216983)  NM_001077479 (human cat#: RC213751)  NM_001077480 (human cat#: RC210209)  
    NM_001077481 (human cat#: RC213852)  NM_001077482 (human cat#: RC213905)  NM_005122 (human cat#: RC216592)  
    NM_009803 (mouse cat#: MR226184)  NM_022941 (rat cat#: RR201357)  
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NR1I3 (see all 15)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 15): NR1I3 (NM_001077480)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NR1I3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NR1I3 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for NR1I3
    Search LifeMap BioReagents cell lines for NR1I3

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NR1I3

    Gene Ontology (GO): 5/12 molecular function terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding TAS9783588
    GO:0003700sequence-specific DNA binding transcription factor activity TAS8114692
    GO:0003707steroid hormone receptor activity ----
    GO:0003713transcription coactivator activity TAS9783588
    GO:0004872receptor activity ----


    NR1I3 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for NR1I3: Nr1i3tm1Neg Nr1i3tm1.1Arte Nr1i3tm1Dgen
         6 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Nr1i3):
     cellular  growth/size  homeostasis/metabolism  liver/biliary system  mortality/aging 
     reproductive system 

    NR1I3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for NR1I3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Nuclear Receptor transcription pathway
    		Nuclear Receptor transcription pathway1.00
    		Nuclear Receptors0.68
    2Generic Transcription Pathway
    		Generic Transcription Pathway1.00
    		Gene Expression0.46
    3Selected targets of GCR-alpha
    		Selected targets of GCR-alpha1.00
    4Drug Induction of Bile Acid Pathway
    		Drug Induction of Bile Acid Pathway1.00
    5Nuclear receptors in lipid metabolism and toxicity
    		Nuclear receptors in lipid metabolism and toxicity1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for NR1I3
        Selected targets of GCR-alpha


    4 BioSystems Pathways for NR1I3 
        Nuclear Receptors
    Nuclear receptors in lipid metabolism and toxicity
    Drug Induction of Bile Acid Pathway
    Glucocorticoid receptor regulatory network

    3        Reactome Pathways for NR1I3
        Generic Transcription Pathway
    Nuclear Receptor transcription pathway
    Gene Expression

    1 PharmGKB Pathway for NR1I3
        Carbamazepine Pathway, Pharmacokinetics


    NR1I3 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NR1I3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/25 Interacting proteins for NR1I3 (Q149943 ENSP000003569594) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MED1Q156483, ENSP000003006514I2D: score=1 STRING: ENSP00000300651
    PPARGC1AQ9UBK23, ENSP000002648674I2D: score=1 STRING: ENSP00000264867
    RXRAP197933, ENSP000004196924I2D: score=2 STRING: ENSP00000419692
    NR0B2Q154663, ENSP000002542274I2D: score=1 STRING: ENSP00000254227
    NCOA1Q157883, ENSP000003209404I2D: score=2 STRING: ENSP00000320940
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent ----
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0006367transcription initiation from RNA polymerase II promoter TAS--
    GO:0007165signal transduction TAS9783588
    GO:0010467gene expression TAS--


    NR1I3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for NR1I3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    NR1I3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Enzo Life Sciences drugs & compounds for NR1I3

    Compounds for NR1I3 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    CITCOSelective CAR agonist--

    7 HMDB Compounds for NR1I3    About this table
    CompoundSynonyms CAS #PubMed Ids
    1-Butanol1-Butanol (see all 10)71-36-3--
    1-Hexanol1-Hexyl alcohol (see all 30)111-27-3--
    1-Pentanol1-Pentol (see all 34)71-41-0--
    Ethanol1-Hydroxyethane (see all 57)64-17-5--
    Isobutanol1-Hydroxymethylpropane (see all 18)78-83-1--
    Isopropyl alcohol2-Propanol (see all 12)67-63-0--
    Propyl alcohol1-Hydroxypropane (see all 17)71-23-8--

    2 DrugBank Compounds for NR1I3    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    (5BETA)-PREGNANE-3,20-DIONE-- --target--10592235
    16,17-Androstene-3-Ol-- 7148-51-8target--10592235

    10/73 Novoseek chemical compound relationships for NR1I3 gene (see all 73)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    androstane 99.2 707 11518807 (4), 12644700 (3), 16635107 (3), 11093784 (2) (see all 99)
    citco 97.5 23 19588937 (2), 16099843 (1), 16929008 (1), 18332083 (1) (see all 10)
    androstanol 91.6 12 15905360 (1), 16929008 (1), 17483497 (1), 18474683 (1) (see all 9)
    tcpobop 87.4 34 15563456 (4), 16101572 (3), 18798339 (3), 18441373 (2) (see all 10)
    androstenol 85 8 11457660 (3), 16929008 (1), 12114525 (1), 9783588 (1) (see all 5)
    phenobarbital 82.5 133 19920082 (5), 10993889 (5), 17904175 (5), 11113125 (3) (see all 48)
    dmes 82.4 14 19034627 (2), 16918318 (1), 18537574 (1), 19695866 (1) (see all 5)
    cinacalcet 78.2 16 16189180 (4), 14696958 (2), 15794735 (1), 17373205 (1) (see all 7)
    rifampicin 73.7 31 18786598 (3), 15919766 (3), 11181490 (2), 19588937 (2) (see all 16)
    metofluthrin 72.1 3 19378387 (1), 19176367 (1)

    Search CenterWatch for drugs/clinical trials and news about NR1I3 

    Transcripts
    for NR1I3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for NR1I3 gene (15 alternative transcripts): 
    NM_001077469.2  NM_001077470.2  NM_001077471.2  NM_001077472.2  NM_001077473.2  NM_001077474.2  NM_001077475.2  NM_001077476.2  
    NM_001077477.2  NM_001077478.2  NM_001077479.2  NM_001077480.2  NM_001077481.2  NM_001077482.2  NM_005122.4  

    Unigene Cluster for NR1I3:

    Nuclear receptor subfamily 1, group I, member 3
    Hs.349642  [show with all ESTs]
    Unigene Representative Sequence: AK303757
    18/34 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 34):
    ENST00000512372 ENST00000367983(uc001fzy.3) ENST00000488651 ENST00000464422
    ENST00000437437 ENST00000479324 ENST00000442691 ENST00000412844 ENST00000428574
    ENST00000505005 ENST00000508740 ENST00000367982 ENST00000506018 ENST00000508387
    ENST00000504010 ENST00000511676 ENST00000502985 ENST00000512340

    miRNA
    Products:             		 OriGene 3'-UTR Clone (see all 8): NR1I3
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NR1I3
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate NR1I3
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NR1I3 (see all 7)
    OriGene shRNA RFP: NR1I3
    OriGene siRNA: NR1I3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NR1I3
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NR1I3 (see all 17)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NR1I3 (see all 15)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 15): NR1I3 (NM_001077480)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for NR1I3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NR1I3 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NR1I3
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NR1I3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NR1I3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NR1I3

    Additional cDNA sequence: 

    AB307702.1 AK303757.1 AK303796.1 AK310773.1 AK316208.1 AY572806.1 AY572808.1 AY572810.1 
    AY572811.1 AY572812.1 AY572813.1 AY572816.1 AY572817.1 AY572818.1 AY572819.1 AY572820.1 
    AY572821.1 AY572822.1 AY572823.1 AY572824.1 AY572825.1 AY572827.1 BC069626.1 BC121120.1 
    BC121121.1 DQ022681.1 HQ692838.1 HQ692839.1 HQ692840.1 HQ692841.1 HQ709178.1 

    14 DOTS entries:

    DT.121424716  DT.118470  DT.95212776  DT.121424516  DT.121424730  DT.75101308  DT.121424744  DT.121424507 
    DT.121424513  DT.121424575  DT.91855775  DT.75170204  DT.91931603  DT.97809200 

    24/70 AceView cDNA sequences (see all 70):

    AY572825 AI262949 BC069626 CB124867 AY572823 AY572806 AY572808 AY572826 
    AV652691 AY572811 BC069651 AY572822 AY572815 AY572809 AY572821 CB157668 
    AY572813 AY572816 AY572824 AY572807 AV652653 AV652750 AY572827 AV661397 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for NR1I3 (see all 12)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10
    SP1:                                                              -           -         
    SP2:                                                  -                       -         
    SP3:                                                  -     -     -           -         
    SP4:        -     -                                                           -         
    SP5:        -     -                                   -                       -         


    ECgene alternative splicing isoforms for NR1I3

    Expression
    for NR1I3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    NR1I3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCCCTCTTCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    NR1I3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LiverLiver LobulePerivenous HepatocytesLiver
    LiverLiver LobuleHepatocytesLiver
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See NR1I3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for NR1I3

    SOURCE GeneReport for Unigene cluster: Hs.349642

    UniProtKB/Swiss-Prot: NR1I3_HUMAN, Q14994
    Tissue specificity: Predominantly expressed in liver

        SABiosciences Expression via Pathway-Focused PCR Array including NR1I3: 
              Nuclear Receptors & Coregulators in human mouse rat

    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NR1I3
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NR1I3
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NR1I3
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NR1I3
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NR1I3

    Orthologs
    for NR1I3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for NR1I3 gene from 5/16 species (see all 16)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves NR1I31 nuclear receptor subfamily 1, group I, member 3 62.5(n)
    57.56(a)    		   395439  NM_204702.1  NP_990033.1 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    NR1I36
    		 --
    		 50(a)
    44(a)
    		 1 ↔ 1
    possible ortholog
    		 GL345063.1(533-5624)
    AAWZ02038821(3849-9082)
    zebrafish
    (Danio rerio)    		 Actinopterygii nr1i26
    		 nuclear receptor subfamily 1, group I, member 2
    		 31(a)
    		 1 → many
    		 9(9724022-9786561)
    fruit fly
    (Drosophila melanogaster)    		 Insecta Hr966
    		 Hormone receptor-like in 96
    		 11(a)
    		 possible ortholog
    		 3R(20850961-20855075)
    worm
    (Caenorhabditis elegans)    		 Secernentea daf-126
    nhr-486
    (see all 3)    		 Nuclear hormone receptor family member nhr-48
    (see all 3)    		 9(a)
    8(a)
    (see all 3)    		 possible ortholog
    possible ortholog
    (see all 3)    		 X(10644344-10666806)
    X(15708153-15716345)


    ENSEMBL Gene Tree for NR1I3 (if available)
    TreeFam Gene Tree for NR1I3 (if available) 

    Paralogs
    for NR1I3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for NR1I3 gene
    VDR2  NR4A32  NR4A12  NR1I22  RARG2  THRB2  RARA2  NR1H22  
    NR4A22  NR1H42  RARB2  THRA2  NR1H32  
    18/59 SIMAP similar genes for NR1I3 using alignment to 22 protein entries:     NR1I3_HUMAN (see all proteins) (see all similar genes):
    THRB    NR3C2    HNF4alpha    NR3C4    AR    ESR2
    NR5A2    VDR    ERRgamma    RXRB    ESRRG    PPARA
    NR3C1    RORA    ESR1    NR1C3    NR4A1    PPARG

    NR1I3 for paralogs           About GeneDecksing



    Genomic Variants
    for NR1I3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/291 NCBI SNPs in NR1I3 are shown (see all 291)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1117813521,2
    		C,F,--132555956(+) GCCCTC/TCTCAG 15 -- ds50013Minor allele frequency- T:0.14CSA WA 122
    rs359371391,2
    		C,--132556317(-) GAAGCA/TCAGAA 15 -- ds50011Minor allele frequency- T:0.01--194
    rs23074171,2
    		C,F--132556358(-) GGGGAA/TAGTGG 15 -- ds50011Minor allele frequency- T:0.01NA 170
    rs23074161,2
    		H--132556429(-) GGCCGG/AGTTCA 22 /S /G ut31 mis1 ese35Minor allele frequency- A:0.00NA NS EA 582
    rs38136291,2
    		H--132556446(+) TTGGTC/TCCAGC 22 E G ut31 mis1 ese34Minor allele frequency- T:0.00NS EA 418
    rs23074141,2
    		C,F,H--132556622(-) TGCTAA/C/GGCCTG 31 S R G mis1 int14NA NS CSA 503
    rs23074211,2
    		C,F,H--132556708(-) TAGAGA/GCAAGA 15 -- int15Minor allele frequency- G:0.27NA NS EA 582
    rs351038721,2
    		C,F,--132556709(-) CTAGAG/AACAAG 15 -- int12Minor allele frequency- A:0.02WA 312
    rs348591881,2
    		C,F,--132556733(-) AGGAAT/CAGTTC 15 -- int12Minor allele frequency- C:0.02WA 312
    rs1124123661,2
    		--132556820(+) AGGGGG/TCCTCG 15 -- int11Minor allele frequency- T:0.50CSA 2

    HapMap Linkage Disequilibrium report for NR1I3 (161199456 - 161208092 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for NR1I3: --
    Human Gene Mutation Database (HGMD): NR1I3

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NR1I3
    DNA2.0 Custom Variant and Variant Library Synthesis for NR1I3

    Disorders / Diseases
    for NR1I3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    NR1I3 for disorders           About GeneDecksing

    OMIM gene information: 603881    OMIM disorders: --

    20/55 diseases for NR1I3 (see all 55):    About MalaCards
    secondary hyperparathyroidism    hyperparathyroidism    rickets    hypocalciuric hypercalcemia
    familial hypocalciuric hypercalcemia    maturity-onset diabetes of the young    hypercalcemia    humoral hypercalcemia of malignancy
    thyroiditis    neonatal jaundice    biliary tract disease    hypocalcemia
    nephrocalcinosis    hypoparathyroidism    hypercalciuria    jaundice
    metabolic disorders    arterial calcification    osteolysis    porphyria

    3 diseases from the University of Copenhagen DISEASES database for NR1I3:
    Cholestasis     Neonatal jaundice     Bilirubin metabolic disorder

    10/39 Novoseek disease relationships for NR1I3 gene (see all 39)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hyperparathyroidism secondary 73.2 15 16189180 (2), 11033758 (1), 16919492 (1), 12830754 (1) (see all 13)
    nshpt 61.3 3 11033758 (1), 9507434 (1)
    hyperparathyroidism 60.1 11 15658669 (2), 8675635 (1), 17018434 (1), 9011580 (1) (see all 9)
    hypercalcemia 58.6 22 11033758 (2), 16189180 (2), 16603723 (2), 18492387 (1) (see all 9)
    hyperparathyroidism primary 57.2 11 11134144 (2), 16189180 (2), 8675635 (1), 9509247 (1) (see all 5)
    parathyroid hyperplasia 54.9 4 12469914 (2), 15888568 (1)
    cholestasis 54.4 8 16565602 (2), 16101572 (1), 19300246 (1), 16025508 (1) (see all 5)
    hypocalcemia 48.2 5 15507543 (1), 17018434 (1), 9757371 (1), 11701698 (1)
    hypoparathyroidism 43.9 10 11701698 (3), 12940896 (1), 9757371 (1), 9768650 (1) (see all 7)
    jaundice neonatal 43.5 3 12644704 (1), 19925451 (1)

    Human Genome Epidemiology (HuGE) Navigator: NR1I3 (7 documents)

    Export disorders for NR1I3 gene to outside databases

    Publications
    for NR1I3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for NR1I3 gene, integrated from 9 sources (see all 505):
    (articles sorted by number of sources associating them with NR1I3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements. (PubMed id 8114692)1, 2, 3 Baes M.... Moore D.D. (1994)
    2. Dephosphorylation of threonine 38 is required for nuc lear translocation and activation of human xenobiotic receptor CAR (NR1I3). (PubMed id 19858220)1, 2, 9 Mutoh S....Negishi M. (2009)
    3. Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences. (PubMed id 15194709)1, 2, 9 Lamba J.K.... Schuetz E.G. (2004)
    4. A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer. (PubMed id 15610735)1, 2, 9 Xu R.X....Moore J.T. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Twenty-six novel single nucleotide polymorphisms and their frequencies of the NR1I3 (CAR) gene in a Japanese population. (PubMed id 15618763)1, 2 Ikeda S.... Sawada J. (2003)
    7. A component of the 26S proteasome binds on orphan member of the nuclear hormone receptor superfamily. (PubMed id 8603043)1, 2 Choi H.S.... Moore D.D. (1996)
    8. Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators. (PubMed id 12114525)1, 9 Min G....Kemper J.K. (2002)
    9. Induction of bilirubin clearance by the constitutive androstane receptor (CAR). (PubMed id 12644704)1, 9 Huang W....Moore D.D. (2003)
    10. Aryl-hydrocarbon receptor activation regulates constitutive androstane receptor levels in murine and human liver. (PubMed id 17596880)1, 9 Patel R.D....Perdew G.H. (2007)

    External Searches for NR1I3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing NR1I3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9970 HGNC: 7969 AceView: NR1I3 Ensembl:ENSG00000143257 euGenes: HUgn9970
    ECgene: NR1I3 H-InvDB: NR1I3

    Other Databases showing NR1I3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing NR1I3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for NR1I3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for NR1I3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for NR1I3 gene:
    Search GeneIP for patents involving NR1I3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for NR1I3 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     Browse Purified and Recombinant Proteins at EMD Millipore
     Browse Small Molecules at EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of NR1I3
     Browse for Gene Knock-down Tools from EMD Millipore
     Browse Kits and Assays available from EMD Millipore
     Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for NR1I3 (CAR/NR1I3)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for NR1I3  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NR1I3   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NR1I3  
     OriGene Protein Over-expression Lysate for NR1I3   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for NR1I3   OriGene 3'-UTR Clone for NR1I3  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NR1I3   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NR1I3  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for NR1I3   OriGene Custom Protein Services for NR1I3  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NR1I3
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NR1I3
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NR1I3
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NR1I3
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NR1I3
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NR1I3
     GenScript Custom Purified and Recombinant Proteins Services for NR1I3 GenScript cDNA clones with any tag delivered in your preferred vector for NR1I3
     GenScript Custom Assay Services for NR1I3 GenScript Custom Superior Antibodies Services for NR1I3
     GenScript Custom overexpressing Cell Line Services for NR1I3 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in NR1I3 promoter
     Search Chromatin IP Primers for NR1I3
     RT2 qPCR Primer Assay in human, mouse, rat NR1I3
     GNC Network for NR1I3
     SABiosciences PCR Arrays including human, mouse, rat NR1I3
     Tocris compounds for NR1I3
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Drugs for NR1I3
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     NR1I3 antibodies
     NR1I3 proteins
     NR1I3 lysates
     Search for Antibodies for NR1I3 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for NR1I3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     NR1I3 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for NR1I3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NR1I3
     Browse SwitchGear 3'UTR luciferase reporter plasmids for NR1I3
     SwitchGear Promoter luciferase reporter plasmids for NR1I3
     Search ThermoFisher Antibodies for NR1I3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NR1I3
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      NR1I3 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4