NPY2R Gene

Aliases
for NPY2R gene

Previous GC identifers: GC04P157017 GC04P156557 GC04P156707 GC04P156671 GC04P156487 GC04P156349 GC04P151868

Summaries
for NPY2R gene

Genomic Views
for NPY2R gene

RefSeq DNA sequence:

NC_000004.11  NC_018915.1  NT_016354.19  

SwitchGear Promoter luciferase reporter plasmid: NPY2R promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NPY2R

NPY2R Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P156129:  view genomic region     (about GC identifiers)

Proteins
for NPY2R gene

1 PDB 3D structure from and Proteopedia for NPY2R:

2IK3 (3D)    

Explore the universe of human proteins at neXtProt for NPY2R: NX_P49146

Post-translational modifications:

	EMD Millipore Purified and/or Recombinant NPY2R Protein
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	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for NPY2R
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	Novus Biologicals NPY2R Proteins
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for NPY2R

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

	EMD Millipore Mono- and Polyclonal Antibodies for the study of NPY2R
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	Uscn Antibodies for NPY2R
	ThermoFisher Antibodies for NPY2R

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	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
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	GenScript Custom Assay Services for NPY2R
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for NPY2R

Protein Domains /
Families
for NPY2R gene

ProtoNet protein and cluster: P49146

Function
for NPY2R gene

miRNA Products:		OriGene 3'-UTR Clone: NPY2R Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NPY2R
		7 QIAGEN miScript miRNA Assays for microRNAs that regulate NPY2R:
		hsa-miR-9 hsa-miR-3658 hsa-miR-922 hsa-miR-29a* hsa-miR-16-1* hsa-miR-944 hsa-miR-3653
		SwitchGear 3'UTR luciferase reporter plasmid: NPY2R 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NPY2R (see all 7) OriGene shRNA RFP: NPY2R OriGene siRNA: NPY2R
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NPY2R

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for NPY2R

Clone Products:		EMD Millipore Clones for the Expression of NPY2R
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NPY2R (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NPY2R OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: NPY2R (NM_000910)
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPY2R

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for NPY2R
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In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPY2R

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

15/16 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Npy2r)

Pathways & Interactions
for NPY2R gene

	Super-pathway	contained gene-specific pathways
1	Class A/1 (Rhodopsin-like receptors)	Class A/1 (Rhodopsin-like receptors) 1.00 G alpha (i) signalling events 0.44 GPCR ligand binding 0.75 GPCRs, Class A Rhodopsin-like 0.41 Peptide ligand-binding receptors 0.61 Neuroactive ligand-receptor interaction 0.38
2	Signaling by GPCR	Signaling by GPCR 1.00 Signal Transduction 0.56 GPCR downstream signaling 0.89
3	Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q	Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q 1.00 Peptide GPCRs 0.46
4	Sympathetic Nerve Pathway (Neuroeffector Junction)	Sympathetic Nerve Pathway (Neuroeffector Junction) 1.00

1 EMD Millipore Pathway for NPY2R

Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q

2 BioSystems Pathways for NPY2R

	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs

5/7        Reactome Pathways for NPY2R

	GPCR downstream signaling
	Peptide ligand-binding receptors
	Signal Transduction
	Signaling by GPCR
	G alpha (i) signalling events

1 PharmGKB Pathway for NPY2R

Sympathetic Nerve Pathway (Neuroeffector Junction)

1         Kegg Pathway  (Kegg details for NPY2R)

Neuroactive ligand-receptor interaction

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

Drugs & Compounds
for NPY2R gene

Transcripts
for NPY2R gene

Expression
for NPY2R gene

NPY2R expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGTATTAGT

3 LifeMap In Vivo Development Anatomical Compartments/Cells
	Tissue Anatomical Compartment Cell			Category (developmental path)
	Spinal CordSpinal Ventral ColumnsVentral Spinal Cord Progenitor Cells			Motor Neurons
	BrainHypothalamus			Brain
	Spinal CordSpinal Ventral Columns			Spinal Cord
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization
Stem Cell Differentiation: 1 LifeMap Cell
	Name			Category
	Beating cell clusters (Spontaneous differen...)

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NPY2R Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NPY2R
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NPY2R
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPY2R

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPY2R

Orthologs
for NPY2R gene

Paralogs
for NPY2R gene

Paralogs for NPY2R gene

GPR83²  HCRTR2²  PRLHR²  NPFFR2²  PPYR1²  NPY5R²  TACR1²  TACR3²  

NPY1R²  QRFPR²  NPFFR1²  HCRTR1²  TACR2²  

16 SIMAP similar genes for NPY2R using alignment to 1 protein entry:     NPY2R_HUMAN:

DRD3    GPR83    NPFFR2    PRLHR    NPFFR1    QRFPR

BRS3    GALR1    NPY1R    PROKR1    PROKR2    TACR1

PPYR1    TACR3    TACR2    HCRTR2

NPY2R for paralogs           About GeneDecksing

Genomic Variants
for NPY2R gene

Disorders / Diseases
for NPY2R gene

17 diseases for NPY2R

1 Novoseek disease relationship for NPY2R gene    About this table

Publications
for NPY2R gene

PubMed articles for NPY2R gene, integrated from 9 sources (see all 109) (see top 10): (articles sorted by number of sources associating them with NPY2R)

Utopia: connect your pdf to the dynamic world of online information

1. Cloning and functional expression of a cDNA encoding a human type 2 neuropeptide Y receptor. (PubMed id 7559383)^{1, 2, 3} Rose P.M.... Seethala R. (1995)
2. Expression cloning of a human brain neuropeptide Y Y2 receptor. (PubMed id 8632753)^{1, 2, 9} Gehlert D.R.... Gadski R.A. (1996)
3. Common neuropeptide Y2 receptor gene variant is protective against obesity among Swedish men. (PubMed id 16331299)^{1, 4} Lavebratt C....Hoffstedt J. (2006)
4. Studies of the peptide YY and neuropeptide Y2 receptor genes in relation to human obesity and obesity-related traits. (PubMed id 15331560)^{1, 4} Hung C.C....Farooqi I.S. (2004)
5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
6. Characterization of the human type 2 neuropeptide Y receptor gene (NPY2R) and localization to the chromosome 4q region containing the type 1 neuropeptide Y receptor gene. (PubMed id 8975716)^{1, 2} Ammar D.A.... Thompson D.A. (1996)
7. Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors. (PubMed id 8643460)^{1, 2} Yan H....Karbon W. (1996)
8. Expression cloning and pharmacological characterization of a human hippocampal neuropeptide Y/peptide YY Y2 receptor subtype. (PubMed id 7592910)^{1, 2} Gerald C....Weinshank R.L. (1995)
9. Single nucleotide polymorphisms in the neuropeptide Y2 receptor (NPY2R) gene and association with severe obesity in French white subjects. (PubMed id 17235527)^{1, 9} Siddiq A....Froguel P. (2007)
10. Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men. (PubMed id 17325259)^{1, 9} Campbell C.D....Hirschhorn J.N. (2007)
11. Importance of a N-terminal aspartate in the internalization of the neuropeptide Y Y2 receptor. (PubMed id 18700141)^{1, 9} Parker S.L....Sallee F. (2008)
12. Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects. (PubMed id 17019604)^{1, 9} Torekov S.S....Pedersen O. (2006)
13. Regional distribution of neuropeptide Y Y2 receptor messenger RNA in the human post mortem brain. (PubMed id 9692752)^{1, 9} Caberlotto L....Hurd Y.L. (1998)
14. Neuropeptide Y2 receptor (NPY2R) expression in saliva predicts feeding immaturity in the premature neonate. (PubMed id 22629465)¹ Maron J.L....Bianchi D.W. (2012)
15. Fluorescence correlation spectroscopy, combined with b imolecular fluorescence complementation, reveals the effects of b-arrestin compl exes and endocytic targeting on the membrane mobility of neuropeptide Y receptor s. (PubMed id 22487268)¹ Kilpatrick L.E....Holliday N.D. (2012)
16. Surface masking shapes the traffic of the neuropeptide Y Y2 receptor. (PubMed id 22732667)¹ Parker M.S....Parker S.L. (2012)
17. High expression of NPY receptors in the human testis. (PubMed id 21295110)¹ KAPrner M....Reubii J.C. (2011)
18. Assessment of a fully active class A G protein-couple d receptor isolated from in vitro folding. (PubMed id 21999704)¹ Bosse M....Schmidt P. (2011)
19. Functional reconstitution of human neuropeptide Y (NP Y) Y(2) and Y(4) receptors in Sf9 insect cells. (PubMed id 21745157)¹ Pop N....Buschauer A. (2011)
20. Identification of positions in the human neuropeptide Y/peptide YY receptor Y2 that contribute to pharmacological differences betwee n receptor subtypes. (PubMed id 21696823)¹ FAollmar H....Larhammar D. (2011)
21. Neuropeptide Y receptors in carotid plaques of sympto matic and asymptomatic patients: effect of inflammatory cytokines. (PubMed id 21352822)¹ Pankajakshan D....Agrawal D.K. (2011)
22. Polymorphisms in the NPY2R gene show significant assoc iations with BMI that are additive to FTO, MC4R, and NPFFR2 gene effects. (PubMed id 21818152)¹ Hunt S.C....Adams T.D. (2011)
23. Variation in the 5'-flanking region of the neuropepti de Y2 receptor gene and metabolic parameters. (PubMed id 20359722)¹ Takiguchi E....Kaji H. (2010)
24. Neuropeptide Y receptor Y2 gene polymorphism interact s with plasma neuropeptide Y levels in predicting left ventricular hypertrophy in dialysis patients. (PubMed id 20543711)¹ Testa A....Zoccali C. (2010)
25. Association study of 182 candidate genes in anorexia nervosa. (PubMed id 20468064)¹ Pinheiro A.P....Woodside D.B. (2010)
26. Association between neuropeptide Y receptor 2 polymor phism and the smoking behavior of elderly Japanese. (PubMed id 20811389)¹ Sato N....Sugimura H. (2010)
27. Ligand-induced internalization and recycling of the h uman neuropeptide Y2 receptor is regulated by its carboxyl-terminal tail. (PubMed id 20959467)¹ Walther C....Beck-Sickinger A.G. (2010)
28. A reconstitution protocol for the in vitro folded hum an G protein-coupled Y2 receptor into lipid environment. (PubMed id 20421142)¹ Schmidt P....Huster D. (2010)
29. In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl) -2-pyridin-3-ylbenzamide), a selective brain penetrant small molecule antagonis t of the neuropeptide Y Y(2) receptor. (PubMed id 19953226)¹ Shoblock J.R....Bonaventure P. (2010)
30. Candidate molecular pathway genes related to appetite regulatory neural network, adipocyte homeostasis and obesity: results from the CARDIA Study. (PubMed id 20642810)¹ Friedlander Y....Siscovick D.S. (2010)
31. Neuropeptide Y and its Y2 receptor: potential targets in neuroblastoma therapy. (PubMed id 20676138)¹ Lu C....Kitlinska J. (2010)
32. Mutagenesis of human neuropeptide Y/peptide YY recept or Y2 reveals additional differences to Y1 in interactions with highly conserve d ligand positions. (PubMed id 20471432)¹ Akerberg H....Larhammar D. (2010)
33. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
34. Variants in neuropeptide Y receptor 1 and 5 are assoc iated with nutrient-specific food intake and are under recent selection in Euro peans. (PubMed id 19759915)¹ Elbers C.C....Onland-Moret N.C. (2009)
35. Cloning and characterization of rabbit neuropeptide Y receptor subtypes. (PubMed id 19481128)¹ Umeda T....Iwaasa H. (2009)
36. Genetical genomic determinants of alcohol consumption in rats and humans. (PubMed id 19874574)¹ Tabakoff B....Hoffman P.L. (2009)
37. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
38. Novel genetic variants contributing to left ventricul ar hypertrophy: the HyperGEN study. (PubMed id 19593212)¹ Arnett D.K....Broeckel U. (2009)
39. A common variant in DRD3 receptor is associated with autism spectrum disorder. (PubMed id 19058789)¹ de Krom M....van Ree J.M. (2009)
40. [Association between obesity and the polymorphism of neuropeptide Y2 receptor gene in children and adolescents] (PubMed id 19957593)¹ Zhang J....Ma J. (2009)
41. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
42. Dissociation of heterotrimeric g proteins in cells. (PubMed id 18577758)¹ Lambert N.A. (2008)
43. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)¹ GratacA^s M....Carracedo A. (2008)
44. The neuropeptide Y (NPY) Y2 receptors are largely dimeric in the kidney, but monomeric in the forebrain. (PubMed id 18569526)¹ Parker S.L....Sallee F.R. (2008)
45. Neuropeptide Y Receptor Genes Are Associated With Alcohol Dependence, Alcohol Withdrawal Phenotypes, and Cocaine Dependence. (PubMed id 18828811)¹ Wetherill L....Foroud T. (2008)
46. Y2 receptor gene variants reduce the risk of hypertension in obese children and adolescents. (PubMed id 18622237)¹ Santoro N....Perrone L. (2008)
47. Chromosome 4q31-34 panic disorder risk locus: association of neuropeptide Y Y5 receptor variants. (PubMed id 17948870)¹ Domschke K....Deckert J. (2008)
48. No association of sequence variants in the neuropeptide Y2 receptor (NPY2R) gene with early onset obesity in Germans. (PubMed id 17992642)¹ Wang H.J....Hinney A. (2007)
49. Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors. (PubMed id 16891622)¹ Movafagh S....Zukowska Z. (2006)
50. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)² Hillier L.W....Wilson R.K. (2005)
51. Variations in peptide YY and Y2 receptor genes are associated with severe obesity in Pima Indian men. (PubMed id 15855352)¹ Ma L....Baier L.J. (2005)
52. High expression of neuropeptide y receptors in tumors of the human adrenal gland and extra-adrenal paraganglia. (PubMed id 15623622)¹ Korner M....Reubi J.C. (2004)
53. Functional consequences of neuropeptide Y Y 2 receptor knockout and Y2 antagonism in mouse and human colonic tissues. (PubMed id 12813010)¹ Hyland N.P....Cox H.M. (2003)
54. Neuropeptide Y Y1 and neuropeptide Y Y2 receptors in human cardiovascular tissues. (PubMed id 12084524)¹ Uddman R....Edvinsson L. (2002)
55. Neuropeptide Y, Y1, Y2 and Y4 receptors mediate Y agonist responses in isolated human colon mucosa. (PubMed id 11906964)¹ Cox H.M. and Tough I.R. (2002)
56. Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status. (PubMed id 12007534)¹ Parker E....Stamford A. (2002)
57. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
58. The peptide YY-preferring receptor mediating inhibition of small intestinal secretion is a peripheral Y(2) receptor: pharmacological evidence and molecular cloning. (PubMed id 11408607)¹ Goumain M....Laburthe M. (2001)
59. GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain. (PubMed id 9651375)¹ Snow B.E....Siderovski D.P. (1998)
60. Neuropeptide Y receptor subtypes. (PubMed id 9001438)¹ Wan C.P. and Lau B.H. (1995)
61. A pertussis toxin-insensitive calcium influx mediated by neuropeptide Y2 receptors in a human neuroblastoma cell line. (PubMed id 8132547)¹ Lynch J.W....Takeda K. (1994)
62. Cloned human neuropeptide Y receptor couples to two different second messenger systems. (PubMed id 1321422)¹ Herzog H.... Selbie L.A. (1992)
63. Cysteamine selectively enhances neuropeptide Y2 recep tor binding activity. (PubMed id 1314592)⁷ Li W. and Hexum T.D. (1992)
64. Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs. (PubMed id 2834384)¹ Itoh H.... Kaziro Y. (1988)
65. Neuropeptide Y2 receptors as drug targets for the central regulation of body weight. (PubMed id 16259221)⁹ Feletou M. and Levens N.R. (2005)
66. Selective and brain penetrant neuropeptide y y2 recep tor antagonists discovered by whole-cell high-throughput screening. (PubMed id 19837904)⁹ Brothers S.P....Hodder P.S. (2010)
67. Neuropeptide Y Y2 receptor in health and disease. (PubMed id 17828288)⁹ Parker S.L. and Balasubramaniam A. (2008)
68. [Expression of neuropeptide Y and its receptors in the cardinal ligaments and uterosacral ligaments in patients with pelvic organ prolapse] (PubMed id 18953866)⁹ Jiang F....Liu J.P. (2008)
69. Patterns of gene expression in pig adipose tissue: insulin-like growth factor system proteins, neuropeptide Y (NPY), NPY receptors, neurotrophic factors and other secreted factors. (PubMed id 18325722)⁹ Hausman G.J....Dean R.G. (2008)
70. Novel cell line selectively expressing neuropeptide Y-Y2 receptors. (PubMed id 14753296)⁹ Hofliger M.M....Beck Sickinger A.G. (2003)
71. Neuropeptide Y Y2 receptor signalling mechanisms in the human glioblastoma cell line LN319. (PubMed id 11287092)⁹ Grouzmann E....Brunner H. (2001)
72. The dog saphenous vein: a sensitive and selective preparation for the Y2 receptor of neuropeptide Y. (PubMed id 9200555)⁹ Pheng L.H....Regoli D. (1997)
73. Cloning and functional expression of a cDNA encoding a mouse type 2 neuropeptide Y receptor. (PubMed id 8914576)⁹ Nakamura M....Hirano D. (1996)
74. Prokaryotic expression, in vitro folding, and molecul ar pharmacological characterization of the neuropeptide Y receptor type 2. (PubMed id 19725122)⁹ Schmidt P....Huster D. (2009)
75. SNP analyses of postprandial responses in (an)orexigenic hormones and feelings of hunger reveal long-term physiological adaptations to facilitate homeostasis. (PubMed id 18957934)⁹ den Hoed M....Westerterp K.R. (2008)
76. Neuropeptide Y Y2 receptor in health and disease. (PubMed id 19060931)⁹ Parker S.L. and Balasubramaniam A. (2008)
77. Emotional behavior in aged neuropeptide Y (NPY) Y2 knockout mice. (PubMed id 16691011)⁹ Carvajal C....Quirion R. (2006)
78. Characterization of NPY receptor subtypes Y2 and Y7 in rainbow trout Oncorhynchus mykiss. (PubMed id 16359756)⁹ Larsson T.A....Larhammar D. (2006)
79. Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1- (2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor. (PubMed id 14617685)⁹ Bonaventure P....Lovenberg T.W. (2004)
80. Reciprocal mutations of neuropeptide Y receptor Y2 in human and chicken identify amino acids important for antagonist binding. (PubMed id 11997008)⁹ Berglund M.M....Larhammar D. (2002)
81. Cloned neuropeptide Y (NPY) Y1 and pancreatic polypeptide Y4 receptors expressed in Chinese hamster ovary cells show considerable agonist-driven internalization, in contrast to the NPY Y2 receptor. (PubMed id 11179953)⁹ Parker S.L....Li M.D. (2001)
82. Molecular characterization of the human neuropeptide Y Y2-receptor. (PubMed id 10346911)⁹ Ingenhoven N....Beck-Sickinger A.G. (1999)
83. Cloning and functional expression of the guinea pig n europeptide Y Y2 receptor. (PubMed id 9802390)⁹ Sharma P....Larhammar D. (1998)
84. Modulation of submucosal arteriolar tone by neuropeptide Y Y2 receptors in the guinea-pig small intestine. (PubMed id 9700058)⁹ Kotecha N. (1998)
85. Distribution of the neuropeptide Y Y2 receptor mRNA in rat central nervous system. (PubMed id 9191097)⁹ Gustafson E.L....Branchek T.A. (1997)
86. Identification of multiple neuropeptide Y receptor subtypes in the human frontal cortex. (PubMed id 9300264)⁹ Statnick M.A....Gehlert D.R. (1997)
87. Neuropeptide Y Y2 receptor and somatostatin sst2 receptor coupling to mobilization of intracellular calcium in SH-SY5Y human neuroblastoma cells. (PubMed id 9031749)⁹ Connor M....Henderson G. (1997)
88. Neuropeptide Y is a vasoconstrictor and adrenergic modulator in the hamster microcirculation by acting on neuropeptide Y1 and Y2 receptors. (PubMed id 8750699)⁹ Boric M.P....Huidobro-Toro J.P. (1995)
89. Reduction of vasoconstriction mediated by neuropeptide Y Y2 receptors in arterioles of the guinea-pig small intestine. (PubMed id 7670724)⁹ Neild T.O. and Lewis C.J. (1995)
90. A novel neuropeptide Y analog, N-acetyl [Leu28,Leu31]neuropeptide Y-(24-36), with functional specificity for the presynaptic (Y2) receptor. (PubMed id 8088364)⁹ Potter E.K....Shine J. (1994)
91. Cyclopeptide analogs for characterization of the neuropeptide Y Y2-receptor. (PubMed id 8450492)⁹ Beck-Sickinger A.G....Jung G. (1993)
92. Schizophrenia-relevant behaviours in a genetic mouse model for Y2 deficiency. (PubMed id 19879900)⁹ Karl T....Herzog H. (2010)
93. Peptide YY. (PubMed id 18185065)⁹ Chandarana K. and Batterham R. (2008)
94. Neuropeptide Y receptors in primary human brain tumors: overexpression in high-grade tumors. (PubMed id 18648328)⁹ Korner M. and Reubi J.C. (2008)
95. Oligomerization of neuropeptide Y (NPY) Y2 receptors in CHO cells depends on functional pertussis toxin-sensitive G-proteins. (PubMed id 17651824)⁹ Parker S.L....Balasubramaniam A. (2007)
96. A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors. (PubMed id 16319069)⁹ Marion S.... Barak L.S. (2006)
97. Localization of novel adiponectin receptor constructs. (PubMed id 17118803)⁹ Deckert C.M....Beck-Sickinger A.G. (2006)
98. Angiogenesis and rhodopsin-like receptors: a role for N-terminal acidic residues? (PubMed id 16023616)⁹ Parker S.L....Sallee F. (2005)
99. Neuropeptide Y and Y2-receptor are involved in development of diabetic retinopathy and retinal neovascularization. (PubMed id 15181979)⁹ Koulu M....Zukowska Z. (2004)
100. Development of a BRET2 screening assay using beta-arrestin 2 mutants. (PubMed id 15191649)⁹ Vrecl M....Heding A. (2004)
101. Neuropeptide Y rapidly reduces Period 1 and Period 2 mRNA levels in the hamster suprachiasmatic nucleus. (PubMed id 11704298)⁹ Fukuhara C....Harrington M.E. (2001)
102. Molecular cloning and characterisation of GPR74 a novel G-protein coupled receptor closest related to the Y-receptor family. (PubMed id 10837915)⁹ Parker R.M.C.... Herzog H. (2000)
103. Neuropeptide Y-induced contraction is mediated by neuropeptide Y Y2 and Y4 receptors in the rat colon. (PubMed id 10422644)⁹ Pheng L.H....Regoli D. (1999)
104. Helical structure and self-association in a 13 residue neuropeptide Y Y2 receptor agonist: relationship to biological activity. (PubMed id 10561544)⁹ Barnham K.J.... Norton R.S. (1999)
105. Neuropeptide Y shifts equilibrium between alpha- and beta-adrenergic tonus in proximal tubule cells. (PubMed id 9688998)⁹ HoltbAock U....Aperia A. (1998)
106. Neuropeptide Y modulates ATP-induced increases in internal calcium via the adenylate cyclase/protein kinase A system in a human neuroblastoma cell line. (PubMed id 9020878)⁹ Soares Lemos V....Takeda K. (1997)

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