Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NPVF Gene

protein-coding GIFtS: 51
GCID: GC07M025264

neuropeptide VF precursor

(Previous name: chromosome 7 open reading frame 9 )
(Previous symbol: C7orf9)

Explore 2 diseases affiliated with
NPVF via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Neuropeptide VF Precursor¹ ²		FMRFamide-Related Peptides²
C7orf9¹ ² ³		Neuropeptide NPVF²
RFRP¹ ² ³		RFamide-Related Peptide²
Chromosome 7 Open Reading Frame 9¹		Neuropeptide VF³

External Ids:	HGNC: 13782¹	Entrez Gene: 64111²	Ensembl: ENSG00000105954⁷	UniProtKB: Q9HCQ7³

Export aliases for NPVF gene to outside databases

Previous GC identifer: GC07M025231

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: RFRP_HUMAN, Q9HCQ7

Function: Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion.

Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory

activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine-induced

analgesia

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NPVF gene promoter:
E2F-4 E2F-3a E2F-5 Lmo2 E2F-2 CREB E2F E2F-1 Nkx6-1 deltaCREB
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NPVF promoter sequence

Search SABiosciences Chromatin IP Primers for NPVF

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NPVF

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p21-p15 Ensembl cytogenetic band: 7p15.3 HGNC cytogenetic band: 7p21-p15

NPVF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NPVF gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M025264: view genomic region (about GC identifiers)

Start:	25,264,189 bp from pter	End:	25,268,105 bp from pter
Size:	3,917 bases	Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 25,315,484-25,319,401

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RFRP_HUMAN, Q9HCQ7 (See protein sequence)

Recommended Name: FMRFamide-related peptides precursor

Size: 196 amino acids; 22309 Da

Subcellular location: Secreted

Mass spectrometry: Mass=1428.85; Method=MALDI; Range=81-92; Source=PubMed:20027225;

Mass spectrometry: Mass=969.56; Method=MALDI; Range=124-131; Source=PubMed:20027225;

Secondary accessions: A4D164 Q7LE27 Q96PI9

Alternative splicing: 2 isoforms: Q9HCQ7-1 Q9HCQ7-2

Explore the universe of human proteins at neXtProt for NPVF: NX_Q9HCQ7

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9HCQ7

NPVF Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_071433.3

ENSEMBL proteins:

ENSP00000222674

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: NPVF OriGene Custom Protein Services for NPVF
	GenScript Custom Purified and Recombinant Proteins Services for NPVF
	Novus Biologicals NPVF Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for NPVF

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0016020	membrane	NAS	--

NPVF for ontologies About GeneDecksing

NPVF Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for NPVF
	GenScript Custom Superior Antibodies Services for NPVF
	Novus Biologicals NPVF Antibody
	Search for Antibodies for NPVF at Abcam
	Uscn Antibodies for NPVF
	Search ThermoFisher Antibodies for NPVF

Assay Products for NPVF:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for NPVF
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for NPVF

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

NPVF for domains About GeneDecksing

1 InterPro domain/family:

IPR026297 FMRFamide-related/fGRP

Graphical View of Domain Structure for InterPro Entry Q9HCQ7

ProtoNet protein and cluster: Q9HCQ7

UniProtKB/Swiss-Prot: RFRP_HUMAN, Q9HCQ7

Similarity: Belongs to the FARP (FMRFamide related peptide) family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: RFRP_HUMAN, Q9HCQ7

Function: Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion.

Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory

activity. Neuropeptide RFRP-1 induces secretion of prolactin in rats. Neuropeptide NPVF blocks morphine-induced

analgesia

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NPVF
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate NPVF:
		hsa-miR-106a* hsa-miR-450b-5p hsa-miR-888*
		SwitchGear 3'UTR luciferase reporter plasmid: NPVF 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NPVF (see all 7) OriGene shRNA RFP: NPVF OriGene siRNA: NPVF
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NPVF

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for NPVF

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NPVF (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NPVF OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: NPVF (NM_022150)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NPVF
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPVF

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for NPVF
		Search LifeMap BioReagents cell lines for NPVF

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPVF

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004930	G-protein coupled receptor activity	NAS	--
GO:0005102	receptor binding	--	--

NPVF for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for NPVF:

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q

Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for NPVF

Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q

NPVF for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NPVF

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for NPVF (Q9HCQ7^{1, 2, 3} ENSP00000222674⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ABL1	P00519¹^,²^,³, ENSP00000361423⁴	EBI-1753111,EBI-375543 MINT-8110671 I2D: score=3 STRING: ENSP00000361423
FYN	P06241¹^,³, ENSP00000357656⁴	EBI-1753111,EBI-515315 I2D: score=2 STRING: ENSP00000357656
NCK1	P16333¹^,³, ENSP00000288986⁴	EBI-1753111,EBI-389883 I2D: score=2 STRING: ENSP00000288986

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007218	neuropeptide signaling pathway	NAS	11025660
GO:0019233	sensory perception of pain	--	--
GO:0032277	negative regulation of gonadotropin secretion	IDA	--

NPVF for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NPVF

1 HMDB Compound for NPVF About this table

Compound	Synonyms	CAS #	PubMed Ids
Cyclic AMP	Cyclic AMP (see all 19)	60-92-4	--

Search CenterWatch for drugs/clinical trials and news about NPVF / RFRP

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NPVF gene:

NM_022150.3

Unigene Cluster for NPVF:

Neuropeptide VF precursor

Hs.60473 [show with all ESTs]

Unigene Representative Sequence: NM_022150

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000222674(uc003sxo.3)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NPVF
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate NPVF:
		hsa-miR-106a* hsa-miR-450b-5p hsa-miR-888*
		SwitchGear 3'UTR luciferase reporter plasmid: NPVF 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NPVF (see all 7) OriGene shRNA RFP: NPVF OriGene siRNA: NPVF
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NPVF

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NPVF (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NPVF OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: NPVF (NM_022150)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for NPVF
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPVF

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NPVF Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat NPVF
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NPVF
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPVF

Additional cDNA sequence:

AB040290.1 AF330057.1 AF440392.1

1 DOTS entry:

DT.208309

14 AceView cDNA sequences:

BU739069 AA017622 AB040290 AA010974 BV203459 BM714303 NM_022150 BG206774

AF330057 AF440392 AA017528 AA011146 BX282962 R84948

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NPVF expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTGACAAAT

About this image

NPVF expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Hypothalamus

Brain

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See NPVF Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NPVF

SOURCE GeneReport for Unigene cluster: Hs.60473

UniProtKB/Swiss-Prot: RFRP_HUMAN, Q9HCQ7

Tissue specificity: Isoform 1 is specifically expressed in the retina. Neuropeptides RFRP-1 and NPVF are detected in

the hypothalamus

SABiosciences Custom PCR Arrays for NPVF

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NPVF Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat NPVF
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NPVF
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPVF

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPVF

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for NPVF gene from 3/9 species (see all 9) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Npvf^{1 , 5}	neuropeptide VF precursor^{1, 5}	72.94(n)¹ 59.68(a)¹		6 (24.34 cM)⁵ 60531¹ NM_021892.1¹ NP_068692.1¹ 50650672⁵
chicken (Gallus gallus)	Aves	NPVF¹	neuropeptide VF precursor	61.74(n) 55.03(a)		378785 NM_204363.1 NP_989694.1
lizard (Anolis carolinensis)	Reptilia	NPVF⁶	--	37(a)	1 ↔ 1	6(31364360-31369085)

ENSEMBL Gene Tree for NPVF (if available)
TreeFam Gene Tree for NPVF (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs5882966^1,2	C,	--	25265528(+)	`CAGAT-/GGGGAT`	1	--	int¹		0	--	--	--	--
rs1018930^1,2	C,F,A,H,	--	25315195(-)	`GTGCCC/TCGCGC`	1	--	ds500¹		20		EA NS NA WA	3880
rs113333837^1,2	F,	--	25315428(+)	`TAGAGG/CCAAAT`	1	--	ds500¹		2		CSA	4
rs11976166^1,2	C,F,H,	--	25315600(+)	`AGAAAC/GACGTT`	1	--	ut3¹ ese³		4		NS EA	416
rs60142768^1,2	C	--	25315681(+)	`TCATAT/ATGTTT`	1	--	ut3¹		1		WA	2
rs55789252^1,2	C,	--	25315838(+)	`AAAATC/GATTTT`	1	--	ut3¹		4		WA NA EA	360
rs978095^1,2	C,F,H,	--	25315851(-)	`GTTACG/ATAAAG`	1	--	ut3¹ ese³		28		MN NS EA NA WA CSA	2784
rs113811642^1,2		--	25315925(+)	`TTGCCA/G/TTTGAT`	2	--	ut3¹		1		CSA	2
rs2717854^1,2	C,F,O,A,H,	--	25316142(-)	`TACACA/TCTTGC`	1	--	int¹		19		EA NA NS WA CSA	1000
rs3801895^1,2	C,F,H,	--	25316226(+)	`ATATTG/TGGGGG`	1	--	int¹		13		EA NS WA NA	2674

HapMap Linkage Disequilibrium report for NPVF (25264189 - 25268105 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for NPVF
1 Indel: 59400

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NPVF

DNA2.0 Custom Variant and Variant Library Synthesis for NPVF

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

NPVF for disorders About GeneDecksing

2 diseases for NPVF: About MalaCards

macular dystrophy retinitis

1 disease from the University of Copenhagen DISEASES database for NPVF:

Pain agnosia

Human Genome Epidemiology (HuGE) Navigator: NPVF (1 document)

Export disorders for NPVF gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for NPVF gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with NPVF)

Utopia: connect your pdf to the dynamic
world of online information

Genomic structure and assessment of the retinally expressed RFamide- related peptide gene in dominant cystoid macular dystrophy. (PubMed id 11951088)^{1, 2, 3, 9} Schulz H.L.... Weber B.H.F. (2002)
New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. (PubMed id 11025660)^{1, 2, 9} Hinuma S.... Fujino M. (2000)
Identification of human GnIH homologs, RFRP-1 and RFR P-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis. (PubMed id 20027225)^{1, 2} Ubuka T....Bentley G.E. (2009)
Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)^{1, 2} Scherer S.W.... Tsui L.-C. (2003)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{1, 2} Hillier L.W.... Wilson R.K. (2003)
Identification and characterization of novel mammalian neuropeptide FF-like peptides that attenuate morphine-induced antinociception. (PubMed id 11481330)^{1, 2} Liu Q.... Austin C.P. (2001)
EST mining of the UniGene dataset to identify retina-specific genes. (PubMed id 11173868)^{1, 3} Stohr H....Weber B.H. (2000)
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)¹ Wu C....Li S.S. (2007)
Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)¹ Bonaldo M.F.... Soares M.B. (1996)
Evidence that RF-amide related peptides are inhibitor s of reproduction in mammals. (PubMed id 19362107)⁹ Clarke I.J....Smith J.T. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 64111	HGNC: 13782	AceView: C7orf9	Ensembl:ENSG00000105954	euGenes: HUgn64111
ECgene: NPVF	H-InvDB: NPVF

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for NPVF	Pharmacogenomics, SNPs, Pathways

Intellectual Property for NPVF gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for NPVF gene:
Search GeneIP for patents involving NPVF

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for NPVF
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NPVF		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NPVF
	OriGene Protein Over-expression Lysate for NPVF		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for NPVF		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NPVF		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NPVF
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for NPVF		OriGene Custom Protein Services for NPVF
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NPVF
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NPVF
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NPVF
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NPVF
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPVF
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NPVF

	GenScript Custom Purified and Recombinant Proteins Services for NPVF		GenScript cDNA clones with any tag delivered in your preferred vector for NPVF
	GenScript Custom Assay Services for NPVF		GenScript Custom Superior Antibodies Services for NPVF
	GenScript Custom overexpressing Cell Line Services for NPVF		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in NPVF promoter
	Search Chromatin IP Primers for NPVF
	RT² qPCR Primer Assay in human, mouse, rat NPVF
	Search GNC Networks for NPVF
	SABiosciences Custom PCR Arrays for NPVF

Search Tocris compounds for NPVF

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	NPVF antibodies
	NPVF lysates

	Search for Antibodies for NPVF at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for NPVF
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

NPVF Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for NPVF

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPVF

	SwitchGear 3'UTR luciferase reporter plasmids for NPVF
	SwitchGear Promoter luciferase reporter plasmids for NPVF

Search ThermoFisher Antibodies for NPVF

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPVF

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes NPVF gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

NPVF Gene

neuropeptide VF precursor

Aliases
for NPVF gene

Summaries
for NPVF gene

Genomic Views
for NPVF gene

Proteins
for NPVF gene

Protein Domains /
Families
for NPVF gene

Function
for NPVF gene

Pathways & Interactions
for NPVF gene

Drugs & Compounds
for NPVF gene

Transcripts
for NPVF gene

Expression
for NPVF gene

Orthologs
for NPVF gene

Paralogs
for NPVF gene

Genomic Variants
for NPVF gene

Disorders / Diseases
for NPVF gene

Publications
for NPVF gene

External Searches for NPVF gene

Genome Databases showing NPVF gene

Other Databases showing NPVF gene

Specialized Databases showing NPVF gene

Intellectual Property
for NPVF gene

Products
for NPVF gene

View Random Gene

Advanced Search

Export list of displayed genes

NPVF Gene

neuropeptide VF precursor

Aliasesfor NPVF gene

Summariesfor NPVF gene

Genomic Viewsfor NPVF gene

Proteinsfor NPVF gene

Protein Domains /Familiesfor NPVF gene

Functionfor NPVF gene

Pathways & Interactionsfor NPVF gene

Drugs & Compoundsfor NPVF gene

Transcriptsfor NPVF gene

Expression for NPVF gene

Orthologsfor NPVF gene

Paralogsfor NPVF gene

Genomic Variantsfor NPVF gene

Disorders / Diseasesfor NPVF gene

Publicationsfor NPVF gene

External Searches for NPVF gene

Genome Databases showing NPVF gene

Other Databases showing NPVF gene

Specialized Databases showing NPVF gene

Intellectual Propertyfor NPVF gene

Productsfor NPVF gene

View Random Gene

Aliases
for NPVF gene

Summaries
for NPVF gene

Genomic Views
for NPVF gene

Proteins
for NPVF gene

Protein Domains /
Families
for NPVF gene

Function
for NPVF gene

Pathways & Interactions
for NPVF gene

Drugs & Compounds
for NPVF gene

Transcripts
for NPVF gene

Expression
for NPVF gene

Orthologs
for NPVF gene

Paralogs
for NPVF gene

Genomic Variants
for NPVF gene

Disorders / Diseases
for NPVF gene

Publications
for NPVF gene

Intellectual Property
for NPVF gene

Products
for NPVF gene