Aliases for NPTXR Gene
External Ids for NPTXR Gene
- HGNC: 7954
- Entrez Gene: 23467
- Ensembl: ENSG00000221890
- OMIM: 609474
- UniProtKB: O95502
Previous GeneCards Identifiers for NPTXR Gene
- GC22M035828
- GC22M037457
- GC22M037538
- GC22M039214
- GC22M022180
Summaries for NPTXR Gene
-
This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species. [provided by RefSeq, Jul 2008]
GeneCards Summary for NPTXR Gene
NPTXR (Neuronal Pentraxin Receptor) is a Protein Coding gene. Diseases associated with NPTXR include Acromesomelic Dysplasia, Maroteaux Type. An important paralog of this gene is NPTX2.
UniProtKB/Swiss-Prot for NPTXR Gene
-
May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPTXR Gene
Genomics for NPTXR Gene
Regulatory Elements for NPTXR Gene
Enhancers for NPTXR Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around NPTXR on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for NPTXR Gene
- Chromosome:
- 22
- Start:
- 38,818,451 bp from pter
- End:
- 38,844,012 bp from pter
- Size:
- 25,562 bases
- Orientation:
- Minus strand
Genomic View for NPTXR Gene
Genes around NPTXR on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q13.1 by Ensembl
- 22q13.1 by Entrez Gene
- 22q13.1 by HGNC
NPTXR Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for NPTXR Gene
Proteins for NPTXR Gene
-
Protein details for NPTXR Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95502-NPTXR_HUMAN
- Recommended name:
- Neuronal pentraxin receptor
- Protein Accession:
- O95502
Protein attributes for NPTXR Gene
- Size:
- 500 amino acids
- Molecular mass:
- 52846 Da
- Cofactor:
- Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
- Quaternary structure:
-
- Heteropentamer with NPTX1 and/or NPTX2. Also binds taipoxin-associated calcium-binding protein 49 (TCBP49/RCN2). Interacts with KLHL2 (By similarity).
- SequenceCaution:
-
- Sequence=CAA15430.3; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for NPTXR Gene
Post-translational modifications for NPTXR Gene
- Ubiquitinated by a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing KLHL2.
- Glycosylation at Asn42, Asn216, and Asn463
- Modification sites at PhosphoSitePlus
Other Protein References for NPTXR Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for NPTXR
- R&D Systems Antibodies for NPTXR (Neuronal Pentraxin R/NPTXR)
- Novus Biologicals Antibodies for NPTXR
- Invitrogen Antibodies for NPTXR
- antibodies-online Antibodies for NPTXR: See all 23
- Search GeneTex for Antibodies for NPTXR
-
Santa Cruz Biotechnology (SCBT) Antibodies for NPTXR
Protein Products
- R&D Systems Proteins and Enzymes for NPTXR (Neuronal Pentraxin R/NPTXR)
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for NPTXR
- Origene Custom Protein Services for NPTXR
- Novus Biologicals proteins for NPTXR
- antibodies-online Proteins for NPTXR: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for NPTXR
Assay Products
- antibodies-online Kits for NPTXR: See all 7
No data available for DME Specific Peptides for NPTXR Gene
Domains & Families for NPTXR Gene
Gene Families for NPTXR Gene
- HGNC:
Protein Domains for NPTXR Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for NPTXR Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for NPTXR Gene
Function for NPTXR Gene
Molecular function for NPTXR Gene
- GENATLAS Biochemistry:
- neuronal pentraxin receptor,interacting with NPTX1,NPTX2 and taipoxin-associated calcium binding protein 49,putatively involved in the clearance of synaptic debris
- UniProtKB/Swiss-Prot Function:
- May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for NPTXR Gene
- MGI mutant phenotypes for NPTXR:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for NPTXR:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Decreased hepcidin::fluc mRNA expression
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased NF-kappaB reporter expression
- Increased transferrin (TF) endocytosis
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Synthetic lethal with vaccinia virus (VACV) infection
Animal Models for NPTXR Gene
- MGI Knock Outs for NPTXR:
-
- Nptxr tm1Mspn
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for NPTXR
-
-
ViGene Biosciences lentiviral particle packaged cDNA for NPTXR gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NPTXR gene
- Search ViGene Biosciences for NPTXR
CRISPR Products
-
OriGene CRISPR knockouts for NPTXR
-
Santa Cruz Biotechnology (SCBT) CRISPR for NPTXR
- GenScript: Design CRISPR guide RNA sequences for NPTXR
miRNA for NPTXR Gene
- miRTarBase miRNAs that target NPTXR
-
- hsa-mir-215-5p (MIRT024464)
- hsa-mir-192-5p (MIRT026767)
- hsa-mir-26b-5p (MIRT029999)
- hsa-mir-6731-5p (MIRT472011)
- hsa-mir-8085 (MIRT472012)
- hsa-mir-6809-5p (MIRT472013)
- hsa-mir-4708-3p (MIRT472014)
- hsa-mir-4784 (MIRT472015)
- hsa-mir-3150b-3p (MIRT472016)
- hsa-mir-5681a (MIRT472017)
- hsa-mir-4441 (MIRT472018)
- hsa-mir-6754-5p (MIRT472019)
- hsa-mir-4270 (MIRT472020)
- hsa-mir-6743-5p (MIRT472021)
- hsa-mir-4688 (MIRT472022)
- hsa-mir-6760-5p (MIRT472023)
- hsa-mir-4643 (MIRT542107)
- hsa-mir-8485 (MIRT542108)
- hsa-mir-5095 (MIRT569703)
- hsa-mir-7151-3p (MIRT569704)
- hsa-mir-767-5p (MIRT569705)
- hsa-mir-502-3p (MIRT569706)
- hsa-mir-501-3p (MIRT569707)
- hsa-mir-4438 (MIRT569708)
- hsa-mir-5047 (MIRT614227)
- hsa-mir-1301-3p (MIRT614228)
- hsa-mir-7156-3p (MIRT614229)
- hsa-mir-4684-3p (MIRT614230)
- hsa-mir-4660 (MIRT619894)
- hsa-mir-4284 (MIRT619895)
- hsa-mir-4772-3p (MIRT619896)
- hsa-mir-1304-3p (MIRT619897)
- hsa-mir-5193 (MIRT619898)
- hsa-mir-4277 (MIRT619899)
- hsa-mir-584-3p (MIRT619900)
- hsa-mir-6890-3p (MIRT619901)
- hsa-mir-1306-5p (MIRT619902)
- hsa-mir-4638-5p (MIRT627931)
- hsa-mir-1307-3p (MIRT627932)
- hsa-mir-6741-3p (MIRT627933)
- hsa-mir-335-5p (MIRT631747)
- hsa-mir-3941 (MIRT636379)
- hsa-mir-4789-3p (MIRT636380)
- hsa-mir-603 (MIRT636381)
- hsa-mir-362-3p (MIRT636382)
- hsa-mir-329-3p (MIRT636383)
- hsa-mir-7641 (MIRT647205)
- hsa-mir-4695-3p (MIRT647206)
miRNA Products
- Search ViGene Biosciences for NPTXR
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for NPTXR
- Browse OriGene Inhibitory RNA Products For NPTXR
-
ViGene Biosciences ready-to-package AAV shRNAs for NPTXR gene
Clone Products
-
OriGene ORF clones in human for NPTXR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for NPTXR
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NPTXR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NPTXR
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for NPTXR
-
ViGene Biosciences adenoviral particle packaged cDNA for NPTXR gene
-
ViGene Biosciences lentiviral particle packaged cDNA for NPTXR gene
-
ViGene Biosciences ready-to-package AAV shRNAs for NPTXR gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for NPTXR Gene
Localization for NPTXR Gene
Subcellular locations from UniProtKB/Swiss-Prot for NPTXR Gene
- Membrane; Single-pass type II membrane protein.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 3 |
| plasma membrane | 2 |
| extracellular | 2 |
| nucleus | 2 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for NPTXR Gene
No Data Available
Interacting Proteins for NPTXR Gene
No data available for Pathways by source and SIGNOR curated interactions for NPTXR Gene
Drugs & Compounds for NPTXR Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| calcium | Nutra | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for NPTXR Gene
mRNA/cDNA for NPTXR Gene
- (2) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (212) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for NPTXR Gene
CRISPR Products
-
OriGene CRISPR knockouts for NPTXR
-
Santa Cruz Biotechnology (SCBT) CRISPR for NPTXR
- GenScript: Design CRISPR guide RNA sequences for NPTXR
miRNA Products
- Search ViGene Biosciences for NPTXR
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for NPTXR
- Browse OriGene Inhibitory RNA Products For NPTXR
-
ViGene Biosciences ready-to-package AAV shRNAs for NPTXR gene
Clone Products
-
OriGene ORF clones in human for NPTXR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for NPTXR
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for NPTXR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NPTXR
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for NPTXR Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for NPTXR Gene
This gene is overexpressed in Brain - Hippocampus (x8.6), Brain - Anterior cingulate cortex (BA24) (x6.5), Brain - Cortex (x6.0), Brain - Amygdala (x6.0), and Brain - Frontal Cortex (BA9) (x5.2).
This gene is overexpressed in Cerebrospinal fluid (62.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for NPTXR Gene
NURSA nuclear receptor signaling pathways regulating expression of NPTXR Gene:
NPTXRSOURCE GeneReport for Unigene cluster for NPTXR Gene:
Hs.91622Evidence on tissue expression from TISSUES for NPTXR Gene
- Nervous system(4.7)
- Heart(2.2)
- Muscle(2.1)
Primer Products
-
OriGene qPCR primer pairs for NPTXR
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for NPTXR Gene
Orthologs for NPTXR Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | NPTXR 35 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | NPTXR 35 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Nptxr 34 16 35 |
|
||
| Npcd 35 |
|
OneToMany | |||
| rat (Rattus norvegicus) |
Mammalia | Nptxr 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | NPTXR 35 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | NPTXR 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | NPTXR 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | NPTXR 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | NPTXR 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | nptxrb 35 34 |
|
OneToMany | |
| nptxra 35 |
|
OneToMany | |||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.3519 34 |
|
- Species where no ortholog for NPTXR was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for NPTXR Gene
Variants for NPTXR Gene
| SNP ID | Clin | Chr 22 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000002129 | -- | 38,842,385(+) | CTGCC(G/T)TGCAC | intron-variant | |
| rs1000123646 | -- | 38,836,563(+) | GACTA(C/T)GGTGA | intron-variant | |
| rs1000129283 | -- | 38,820,014(+) | GTGCT(A/G)TCACC | utr-variant-3-prime | |
| rs1000160567 | -- | 38,819,791(+) | TCCTC(C/T)TTCCC | utr-variant-3-prime | |
| rs1000189475 | -- | 38,835,407(+) | GTGGT(A/G)GGCAA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv769n67 | CNV | gain | 20364138 |
| esv2724233 | CNV | deletion | 23290073 |
| esv2724234 | CNV | deletion | 23290073 |
| nsv1073162 | CNV | deletion | 25765185 |
| nsv1133541 | CNV | deletion | 24896259 |
| nsv1144972 | CNV | deletion | 24896259 |
| nsv471199 | CNV | loss | 18288195 |
| nsv589009 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
29.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.74;
32.98% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for NPTXR Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- NPTXR
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NPTXR Gene
Disorders for NPTXR Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| acromesomelic dysplasia, maroteaux type |
|
|
Search NPTXR in MalaCards
View complete list of genes associated with diseases
Relevant External Links for NPTXR
No data available for UniProtKB/Swiss-Prot and Genatlas for NPTXR Gene
Publications for NPTXR Gene
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
- Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases. (PMID: 19368810) Yin G.N. … Suk K. (Brain Res. 2009) 3 22 64
- Regulation of neuronal type genes in congestive heart failure rats. (PMID: 16497176) Andersson K.B. … Christensen G. (Acta Physiol (Oxf) 2006) 2 3 64
- Specific sensitivity of small cell lung cancer cell lines to the snake venom toxin taipoxin. (PMID: 16115696) Poulsen T.T. … Poulsen H.S. (Lung Cancer 2005) 3 22 64
- The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 3 4 64
Products for NPTXR Gene
- R&D Systems Antibodies for NPTXR (Neuronal Pentraxin R/NPTXR)
- R&D Systems Proteins and Enzymes for NPTXR (Neuronal Pentraxin R/NPTXR)
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
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- Browse ELISAs
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- OriGene qPCR primer pairs for NPTXR
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- GenScript: Next-day shipping cDNA ORF clone for NPTXR in any vector
- GenScript Custom Purified and Recombinant Proteins Services for NPTXR
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- GenScript Custom overexpressing Cell Line Services for NPTXR
- GenScript: Design CRISPR guide RNA sequences for NPTXR
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- Sino Biological Human cDNA Clone for NPTXR
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for NPTXR
- Novus Biologicals proteins for NPTXR
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for NPTXR: See all 23
- antibodies-online Kits for NPTXR: See all 7
- antibodies-online Proteins for NPTXR: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for NPTXR
- Search GeneTex for Proteins for NPTXR
- ViGene Biosciences adenoviral particle packaged cDNA for NPTXR gene
- ViGene Biosciences lentiviral particle packaged cDNA for NPTXR gene
- ViGene Biosciences ready-to-package AAV shRNAs for NPTXR gene
- Search ViGene Biosciences for NPTXR
- Santa Cruz Biotechnology (SCBT) Antibodies for NPTXR
- Search Santa Cruz Biotechnology (SCBT) for NPTXR siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for NPTXR
- Horizon Cell Lines for NPTXR
- Cyagen custom Knockout/knockin (KOKI) mouse models for NPTXR
- VectorBuilder custom plasmid, inducible vectors for NPTXR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for NPTXR
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for NPTXR Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
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