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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

NPTXR Gene

protein-coding GIFtS: 53
GCID: GC22M039214

Neuronal Pentraxin Receptor

Microbiology & Infectious Diseases Congress

See related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Neuronal Pentraxin Receptor¹ ²
NPR²

External Ids:	HGNC: 7954¹	Entrez Gene: 23467²	Ensembl: ENSG00000221890⁷	OMIM: 609474⁵	UniProtKB: O95502³

Export aliases for NPTXR gene to outside databases

Previous GC identifers: GC22M035828 GC22M037457 GC22M037538 GC22M022180

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for NPTXR Gene:

This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an

integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its

transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG)

codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species.

(provided by RefSeq, Jul 2008)

GeneCards Summary for NPTXR Gene:

NPTXR (neuronal pentraxin receptor) is a protein-coding gene. Diseases associated with NPTXR include acromesomelic dysplasia, and congestive heart failure. GO annotations related to this gene include metal ion binding. An important paralog of this gene is NPTX2.

UniProtKB/Swiss-Prot: NPTXR_HUMAN, O95502

Function: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the

synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses (By similarity)

Gene Wiki entry for NPTXR Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000022.10 NC_018933.2 NT_011520.12

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the NPTXR gene promoter:
HOXA9 HOXA9B AML1a Pax-5 Lmo2 AP-4 Evi-1 Meis-1b HOXA5 Meis-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: NPTXR promoter sequence

Search SABiosciences Chromatin IP Primers for NPTXR

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NPTXR

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1 Ensembl cytogenetic band: 22q13.1 HGNC cytogenetic band: 22q13.1

NPTXR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NPTXR gene location

GeneLoc information about chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22M039214: view genomic region (about GC identifiers)

Start:	39,214,456 bp from pter	End:	39,240,017 bp from pter
Size:	25,562 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NPTXR_HUMAN, O95502 (See protein sequence)

Recommended Name: Neuronal pentraxin receptor

Size: 500 amino acids; 52846 Da

Cofactor: Binds 2 calcium ions per subunit (By similarity)

Subunit: Heteropentamer with NPTX1 and/or NPTX2. Also binds taipoxin-associated calcium-binding protein 49

(TCBP49/RCN2). Interacts with KLHL2 (By similarity)

Subcellular location: Membrane; Single-pass type II membrane protein (Potential)

Sequence caution: Sequence=CAA15430.3; Type=Erroneous gene model prediction;

Explore the universe of human proteins at neXtProt for NPTXR: NX_O95502

Explore proteomics data for NPTXR at MOPED

Post-translational modifications:

UniProtKB: Ubiquitinated by a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing KLHL2 (By

similarity)

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_O95502

NPTXR Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_055108.2

ENSEMBL proteins:

ENSP00000327545

Human Recombinant Protein Products for NPTXR:

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	Cloud-Clone Corp. Proteins for NPTXR

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016021	integral to membrane	IEA	--

NPTXR for ontologies About GeneDecksing

NPTXR Antibody Products:

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	Novus Biologicals NPTXR Antibodies
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	LSBio Antibodies in human, mouse, rat for NPTXR

Assay Products for NPTXR:

	Browse Kits and Assays available from EMD Millipore
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	Cloud-Clone Corp. ELISAs for NPTXR Cloud-Clone Corp. CLIAs for NPTXR

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

3 InterPro protein domains:

IPR013320 ConA-like_subgrp

IPR001759 Pentaxin

IPR008985 ConA-like_lec_gl_sf

Graphical View of Domain Structure for InterPro Entry O95502

ProtoNet protein and cluster: O95502

1 Blocks protein domain: IPB001759 Pentaxin

UniProtKB/Swiss-Prot: NPTXR_HUMAN, O95502

Similarity: Contains 1 pentaxin domain

NPTXR for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: NPTXR_HUMAN, O95502

Function: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the

synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses (By similarity)

Genatlas biochemistry entry for NPTXR:

neuronal pentraxin receptor,interacting with NPTX1,NPTX2 and taipoxin-associated calcium binding protein

49,putatively involved in the clearance of synaptic debris

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0046872	metal ion binding	IEA	--

NPTXR for ontologies About GeneDecksing

Phenotypes:
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Nptxr):

nervous system

NPTXR for phenotypes About GeneDecksing

Animal Models:
MGI mouse knock-out Nptxr^tm1Mspn for NPTXR

inGenious Targeting Laboratory - Custom generated mouse model solutions for NPTXR

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for NPTXR

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NPTXR

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NPTXR

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NPTXR
		8/46 QIAGEN miScript miRNA Assays for microRNAs that regulate NPTXR (see all 46):
		hsa-miR-128 hsa-miR-30d hsa-miR-4314 hsa-miR-30a hsa-miR-149 hsa-miR-330-3p hsa-miR-761 hsa-miR-3144-5p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for NPTXR
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPTXR

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for NPTXR

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

4 Interacting proteins for NPTXR (O95502³ ENSP00000327545⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NPTX2	P47972³, ENSP00000265634⁴	I2D: score=1 STRING: ENSP00000265634
NPTX1	Q15818³, ENSP00000307549⁴	I2D: score=1 STRING: ENSP00000307549
GBAS	O75323³	I2D: score=1
WIPI2	Q9Y4P8³	I2D: score=1

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

NPTXR for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for NPTXR

1 HMDB Compound for NPTXR About this table

Compound	Synonyms	CAS #	PubMed Ids
Calcium	Ca (see all 2)	7440-70-2	--

2 Novoseek inferred chemical compound relationships for NPTXR gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
cgmp	45.3	1	10446136 (1)
nadph	20.5	3	15089095 (2), 15547247 (1)

Search CenterWatch for drugs/clinical trials and news about NPTXR

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for NPTXR gene (2 alternative transcripts):

NM_014293.3 NM_058178.1

Unigene Cluster for NPTXR:

Neuronal pentraxin receptor

Hs.91622 [show with all ESTs]

Unigene Representative Sequence: NM_014293

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000333039(uc003awk.3)

Congresses - knowledge worth sharing:
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat NPTXR
		8/46 QIAGEN miScript miRNA Assays for microRNAs that regulate NPTXR (see all 46):
		hsa-miR-128 hsa-miR-30d hsa-miR-4314 hsa-miR-30a hsa-miR-149 hsa-miR-330-3p hsa-miR-761 hsa-miR-3144-5p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NPTXR
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPTXR

Additional mRNA sequence:

AF052163.1 AL161974.1 AL162057.1 BC043606.1

6 DOTS entries:

DT.100781229 DT.448345 DT.100781231 DT.120650937 DT.433700 DT.91909871

24/212 AceView cDNA sequences (see all 212):

D51955 BU632940 AI014314 BQ230962 BM664678 H41734 AL118608 AW963649

BC043606 T33852 BU856929 AF052163 R88792 AA372919 CB152312 BX090839

NM_058178 T30973 BE048263 AA322700 CD635635 D52028 BM722090 CD635634

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

NPTXR expression in normal human tissues (normalized intensities) NPTXR embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: CTGTTTAAAA

About this image

NPTXR expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/2 selected tissues (see all 2) fully expand


Brain (Nervous System) fully expand to see all 2 entries
Amygdala
prefrontal cortex

Testis (Reproductive System)

See NPTXR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for NPTXR

SOURCE GeneReport for Unigene cluster: Hs.91622

SABiosciences Custom PCR Arrays for NPTXR

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPTXR

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPTXR

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for NPTXR gene from 4/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Nptxr^{1 , 5}	neuronal pentraxin receptor^{1, 5}	88.03(n)¹ 90.47(a)¹		15 (37.85 cM)⁵ 73340¹ NM_030689.4¹ NP_109614.2¹ 79786353⁵
chicken (Gallus gallus)	Aves	NPTXR⁶	Uncharacterized protein	33(a)	possible ortholog	1(50627427-50649375)
lizard (Anolis carolinensis)	Reptilia	--	--	31(a)	possible ortholog	5(24307274-24385885)
zebrafish (Danio rerio)	Actinopterygii	nptxrb¹	neuronal pentraxin receptor b	56.61(n) 50(a)		100005257 NM_001044314.1 NP_001037779.1

ENSEMBL Gene Tree for NPTXR (if available)
TreeFam Gene Tree for NPTXR (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for NPTXR gene

NPTX2² APCS² CRP² PTX4² NPTX1² PTX3²

2 SIMAP similar genes for NPTXR using alignment to 1 protein entry: NPTXR_HUMAN:

NPTX2 NPTX1

NPTXR for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 22 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs145231876^1,2	C	untested¹	39222748(+)	`GCTGAG/AGACCC`	2	/S	syn¹		1		NA	4546
rs116942161^1,2	C,F	--	22206071(+)	`GTCCAA/GGGTCA`	1	--	int¹		1		EA	120
rs12628473^1,2	C,H	--	22206303(+)	`TCATTA/GCAGAA`	1	--	int¹		2		CSA EA	122
rs12628497^1,2	C,A,H	--	22206306(+)	`TTACAG/AAATCT`	1	--	int¹		3		CSA WA EA	240
rs181231180^1,2		--	22206349(+)	`TCCTCC/TGAATC`	1	--	int¹		0	--	--	--	--
rs187094934^1,2		--	22206387(+)	`AGAGAA/TACCCC`	1	--	int¹		0	--	--	--	--
rs11913354^1,2	C,F,H	--	22206413(+)	`TCTGCC/TTTCGT`	1	--	int¹		1		WA	118
rs146109022^1,2		--	22206589(+)	`TAAAAA/GCAATC`	1	--	int¹		0	--	--	--	--
rs190629910^1,2	C	--	22206639(+)	`ATGAGA/GTCTTT`	1	--	int¹		0	--	--	--	--
rs183543611^1,2		--	22206657(+)	`AATACA/GGATTC`	1	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for NPTXR (39214456 - 39240017 bp)

Structural Variations
Database of Genomic Variants (DGV) 9 variations for NPTXR: About this table

Variant ID	Type	Subtype	PubMed ID
esv2724234	CNV	Deletion	23290073
esv2724233	CNV	Deletion	23290073
nsv915071	CNV	Loss	21882294
nsv915070	CNV	Loss	21882294
nsv915069	CNV	Loss	21882294
nsv471199	CNV	Loss	18288195
nsv915068	CNV	Loss	21882294
nsv915067	CNV	Loss	21882294
dgv769n67	CNV	Gain	20364138

SABiosciences Cancer Mutation PCR Assays

SeqTarget long-range PCR primers for resequencing NPTXR

DNA2.0 Custom Variant and Variant Library Synthesis for NPTXR

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

OMIM gene information: 609474 OMIM disorders: --

8 diseases for NPTXR: About MalaCards

acromesomelic dysplasia congestive heart failure neuronitis obesity

adenoma hypertension lung cancer hepatitis

NPTXR for disorders About GeneDecksing

Congresses - knowledge worth sharing:
Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
Genetic Association Database (GAD): NPTXR
Human Genome Epidemiology (HuGE) Navigator: NPTXR (1 document)

Export disorders for NPTXR gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for NPTXR gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with NPTXR)

Utopia: connect your pdf to the dynamic
world of online information

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)^{1, 4} Rose J.E....Uhl G.R. (2010)
Regulation of neuronal type genes in congestive heart failure rats. (PubMed id 16497176)^{1, 3} Andersson K.B....Christensen G. (2006)
The DNA sequence of human chromosome 22. (PubMed id 10591208)^{1, 2} Dunham I....O'Brien K.P. (1999)
Neuronal pentraxin receptor, a novel putative integral membrane pentraxin that interacts with neuronal pentraxin 1 and 2 and taipoxin-associated calcium-binding protein 49. (PubMed id 9261167)^{1, 9} Dodds D.C....Perin M.S. (1997)
Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases. (PubMed id 19368810)^{1, 9} Yin G.N....Suk K. (2009)
Specific sensitivity of small cell lung cancer cell lines to the snake venom toxin taipoxin. (PubMed id 16115696)^{1, 9} Poulsen T.T....Poulsen H.S. (2005)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Biochemical interactions of the neuronal pentraxins. Neuronal pentraxin (NP) receptor binds to taipoxin and taipoxin-associated calcium-binding protein 49 via NP1 and NP2. (PubMed id 10748068)¹ Kirkpatrick L.L....Perin M.S. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

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Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 23467	HGNC: 7954	AceView: NPTXR	Ensembl:ENSG00000221890	euGenes: HUgn23467
ECgene: NPTXR	H-InvDB: NPTXR

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for NPTXR	Pharmacogenomics, SNPs, Pathways

Intellectual Property for NPTXR gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for NPTXR gene:
Search GeneIP for patents involving NPTXR

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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NPTXR Gene

Neuronal Pentraxin Receptor

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NPTXR Gene

Neuronal Pentraxin Receptor

Aliasesfor NPTXR gene

Summariesfor NPTXR gene

Genomic Viewsfor NPTXR gene

Proteinsfor NPTXR gene

Protein Domains /Familiesfor NPTXR gene

Functionfor NPTXR gene

Pathways & Interactionsfor NPTXR gene

Drugs & Compoundsfor NPTXR gene

Transcriptsfor NPTXR gene

Expression for NPTXR gene

Orthologsfor NPTXR gene

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Disorders / Diseasesfor NPTXR gene

Publicationsfor NPTXR gene

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Genome Databases showing NPTXR gene

Other Databases showing NPTXR gene

Specialized Databases showing NPTXR gene

Intellectual Propertyfor NPTXR gene

Productsfor NPTXR gene

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Aliases
for NPTXR gene

Summaries
for NPTXR gene

Genomic Views
for NPTXR gene

Proteins
for NPTXR gene

Protein Domains /
Families
for NPTXR gene

Function
for NPTXR gene

Pathways & Interactions
for NPTXR gene

Drugs & Compounds
for NPTXR gene

Transcripts
for NPTXR gene

Expression
for NPTXR gene

Orthologs
for NPTXR gene

Paralogs
for NPTXR gene

Genomic Variants
for NPTXR gene

Disorders / Diseases
for NPTXR gene

Publications
for NPTXR gene

Intellectual Property
for NPTXR gene

Products
for NPTXR gene