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NPTX1 Gene

protein-coding   GIFtS: 56
GCID: GC17M078440

Neuronal Pentraxin I

  See NPTX1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Neuronal Pentraxin I1 2 3
NP12 3 5
NP-I2 3
Neuronal Pentraxin-12

External Ids:    HGNC: 79521   Entrez Gene: 48842   Ensembl: ENSG000001712467   OMIM: 6023675   UniProtKB: Q158183   
ORGUL members:         

Export aliases for NPTX1 gene to outside databases

Previous GC identifers: GC17M078086 GC17M081759 GC17M079003 GC17M079141 GC17M076055 GC17M073881


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for NPTX1 Gene:
NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which
encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the
nervous system. (provided by RefSeq, Jul 2008)

GeneCards Summary for NPTX1 Gene:
NPTX1 (neuronal pentraxin I) is a protein-coding gene. Diseases associated with NPTX1 include wallerian degeneration, and prostate cancer. An important paralog of this gene is NPTX2.

UniProtKB/Swiss-Prot: NPTX1_HUMAN, Q15818
Function: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the
synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses (By similarity)

Gene Wiki entry for NPTX1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the NPTX1 gene promoter:
         E2F-4   E2F-3a   E2F-5   Pax-5   NRSF form 1   Lmo2   E2F-2   NRSF form 2   E2F   E2F-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for NPTX1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat NPTX1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.3   Ensembl cytogenetic band:  17q25.3   HGNC cytogenetic band: 17q25.3

NPTX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
NPTX1 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M078440:  view genomic region     (about GC identifiers)

Start:
78,440,633 bp from pter      End:
78,451,643 bp from pter
Size:
11,011 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: NPTX1_HUMAN, Q15818 (See protein sequence)
Recommended Name: Neuronal pentraxin-1 precursor  
Size: 432 amino acids; 47122 Da
Cofactor: Binds 2 calcium ions per subunit (By similarity)
Subunit: Homooligomer or heterooligomer (probably pentamer) with neuronal pentraxin receptor (NPTXR) (By
similarity)
Secondary accessions: B3KXH3 Q5FWE6

Explore the universe of human proteins at neXtProt for NPTX1: NX_Q15818

Explore proteomics data for NPTX1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn154, Asn193
  • Modification sites at PhosphoSitePlus

  • See NPTX1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_002513.2  
    ENSEMBL proteins: 
     ENSP00000307549  

    NPTX1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for NPTX1

     
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    EMD Millipore Mono- and Polyclonal Antibodies for the study of NPTX1
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR013320 ConA-like_subgrp
     IPR001759 Pentaxin
     IPR008985 ConA-like_lec_gl_sf

    Graphical View of Domain Structure for InterPro Entry Q15818

    ProtoNet protein and cluster: Q15818

    1 Blocks protein domain: IPB001759 Pentaxin

    UniProtKB/Swiss-Prot: NPTX1_HUMAN, Q15818
    Similarity: Contains 1 pentaxin domain


    Find genes that share domains with NPTX1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NPTX1_HUMAN, Q15818
    Function: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the
    synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses (By similarity)

         Genatlas biochemistry entry for NPTX1:
    pentaxin (pentraxin) 1,neuronal,mediating the uptake of synaptic material and presynaptic toxins

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with NPTX1           About GenesLikeMe


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Nptx1):
     behavior/neurological  nervous system  vision/eye 

    Find genes that share phenotypes with NPTX1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Nptx1tm1Mspn for NPTX1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for NPTX1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for NPTX1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for NPTX1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for NPTX1

    miRNA
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    miRTarBase miRNAs that target NPTX1:
    hsa-mir-10b-5p (MIRT047499), hsa-mir-210-3p (MIRT001930), hsa-mir-760 (MIRT036754), hsa-mir-10a-5p (MIRT047746), hsa-mir-615-3p (MIRT040023), hsa-let-7a-5p (MIRT052609), hsa-let-7c-5p (MIRT051875)

    Block miRNA regulation of human, mouse, rat NPTX1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate NPTX1 (see all 116):
    hsa-miR-3152-3p hsa-miR-520f hsa-miR-1224-3p hsa-miR-200a hsa-miR-128 hsa-miR-1260b hsa-miR-632 hsa-miR-10b*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for NPTX1
    Predesigned siRNA for gene silencing in human, mouse, rat NPTX1

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: NPTX1 (NM_002522)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPTX1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPTX1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NPTX1_HUMAN, Q15818: Cytoplasmic vesicle, secretory vesicle (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular2
    lysosome1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005739mitochondrion IEA--
    GO:0005886plasma membrane IEA--
    GO:0030133transport vesicle IEA--
    GO:0043005neuron projection IEA--

    Find genes that share ontologies with NPTX1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Arrays including NPTX1: 
              Polycomb & Trithorax Target Genes in human mouse rat
              Antifungal Response in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for NPTX1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for NPTX1 (Q158183 ENSP000003075494) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NPTXRO955023, ENSP000003275454I2D: score=1 STRING: ENSP00000327545
    PLXNA1Q9UIW23, ENSP000002517724I2D: score=1 STRING: ENSP00000251772
    RCN2Q142573, ENSP000003783494I2D: score=1 STRING: ENSP00000378349
    SUMO1ENSP000003760764STRING: ENSP00000376076
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport TAS8884281
    GO:0006839mitochondrial transport IEA--
    GO:0007268synaptic transmission TAS8884281
    GO:0007417central nervous system development TAS8884281
    GO:0035865cellular response to potassium ion IEA--

    Find genes that share ontologies with NPTX1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for NPTX1

    1 HMDB Compound for NPTX1    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    8 Novoseek inferred chemical compound relationships for NPTX1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    mibolerone 74.3 8 12865321 (3), 15001595 (2)
    vegf 63.1 48 14666697 (4), 15126502 (4), 12385828 (4), 16376649 (3) (see all 14)
    iodide 53.8 3 15001595 (1), 11103823 (1), 12865321 (1)
    heparin 4.77 3 16899214 (2), 10842181 (1)
    tyrosine 0 4 10842181 (1), 15655556 (1), 11238106 (1)
    potassium 0 10 11031272 (4), 15630079 (4)
    lactate 0 1 8427710 (1)
    glutamate 0 3 15115814 (1), 16054439 (1), 17936538 (1)



    Find genes that share compounds with NPTX1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for NPTX1 gene: 
    NM_002522.3  

    Unigene Cluster for NPTX1:

    Neuronal pentraxin I
    Hs.514556  [show with all ESTs]
    Unigene Representative Sequence: BX537550
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000535681 ENST00000306773(uc002jyp.1) ENST00000571100 ENST00000575212

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate NPTX1 (see all 116):
    hsa-miR-3152-3p hsa-miR-520f hsa-miR-1224-3p hsa-miR-200a hsa-miR-128 hsa-miR-1260b hsa-miR-632 hsa-miR-10b*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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      QuantiTect SYBR Green Assays in human, mouse, rat NPTX1
      QuantiFast Probe-based Assays in human, mouse, rat NPTX1

    Additional mRNA sequence: 

    AK127335.1 BC089441.1 BX537550.1 U61849.1 

    5 DOTS entries:

    DT.87016482  DT.100009436  DT.120995880  DT.100676946  DT.120995879 

    Selected AceView cDNA sequences (see all 93):

    BX110854 AL119012 AL133850 AA322950 BE700028 BE699746 T08921 AI798972 
    AU132539 AA325986 AI990517 AI340069 CB051379 CK004047 AK124701 BE700230 
    BE220979 CF128345 BM476088 BF667116 BE700046 AI088841 CD673942 AA322317 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    NPTX1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATTGTTGAG
    NPTX1 Expression
    About this image


    NPTX1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebellum
     
     Cartilage (Muscoskeletal System)
             Intervertebral disc (IVD) annulus fibrosus (AF) cells
    NPTX1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    NPTX1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.514556
        Pathway & Disease-focused RT2 Profiler PCR Arrays including NPTX1: 
              Polycomb & Trithorax Target Genes in human mouse rat
              Antifungal Response in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPTX1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for NPTX1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Nptx11 , 5 neuronal pentraxin 11, 5 91.67(n)1
    96.3(a)1
      11 (83.95 cM)5
    181641  NM_008730.21  NP_032756.11 
     1195387195 
    chicken
    (Gallus gallus)
    Aves NPTX11 neuronal pentraxin I 83.17(n)
    83.9(a)
      422078  XM_420081.4  XP_420081.3 
    lizard
    (Anolis carolinensis)
    Reptilia NPTX16
    neuronal pentraxin I
    81(a)
    1 ↔ 1
    2(100252067-100258634)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia nptx11 neuronal pentraxin 1 71.63(n)
    78.54(a)
      100158577  NM_001128007.1  NP_001121479.1 
    zebrafish
    (Danio rerio)
    Actinopterygii nptx1l1 neuronal pentraxin 1 like 74.61(n)
    77.89(a)
      405872  NM_212936.1  NP_998101.1 


    ENSEMBL Gene Tree for NPTX1 (if available)
    TreeFam Gene Tree for NPTX1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for NPTX1 gene
    NPTX22  APCS2  CRP2  PTX42  NPTXR2  PTX32  
    3 SIMAP similar genes for NPTX1 using alignment to 1 protein entry:     NPTX1_HUMAN:
    NPTX2    NPTXR    CRP

    Find genes that share paralogs with NPTX1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for NPTX1 (see all 289)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1848024651,2
    --78440200(+) AAAGCA/GGGAAG 1 -- ds50010--------
    rs1382626581,2
    --78440230(+) GCCCCA/GCTAGC 1 -- ds50010--------
    rs75032191,2
    C,F,H--78440293(+) CACCTC/TGAACC 1 -- ds500116Minor allele frequency- T:0.25NS EA NA 2222
    rs1897788711,2
    --78440319(+) ACCGCA/GAGTCC 1 -- ds50010--------
    rs1492019481,2
    --78440348(+) AATGCA/GGAGTG 1 -- ds50010--------
    rs572703341,2
    C,F--78440558(+) TGGCTG/AGGGAA 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs604577961,2
    C--78440700(+) AAAAA-/AGCAAG 1 -- ut312Minor allele frequency- A:0.00NA CSA 4
    rs1393495141,2
    --78440802(+) CCAAAA/GGGCTG 1 -- ut310--------
    rs116529661,2
    C,F,H--78440867(+) ACATCG/AATTCT 1 -- ut3118Minor allele frequency- A:0.08NS EA NA WA 1964
    rs1428152821,2
    --78440925(+) GGTTT-/GCTTTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for NPTX1 (78440633 - 78451643 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for NPTX1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv908992CNV Loss21882294
    dgv3299n71CNV Loss21882294
    nsv524479CNV Loss19592680
    dgv3300n71CNV Loss21882294
    nsv828126CNV Loss20364138
    dgv539n67CNV Gain20364138
    nsv828127CNV Gain20364138
    esv24254CNV Gain+Loss19812545

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602367    OMIM disorders: --

    2 diseases for NPTX1:    
    About MalaCards
    wallerian degeneration    prostate cancer


    Find genes that share disorders with NPTX1           About GenesLikeMe

    4 Novoseek inferred disease relationships for NPTX1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    prostate cancer 20.9 2 14666697 (2)
    breast carcinoma 4.17 1 16513643 (1)
    metastasis 0 4 16773190 (2), 14666697 (1)
    tumors 0 24 16773190 (3), 11103823 (2), 18787945 (1), 12480257 (1) (see all 5)


    Export disorders for NPTX1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for NPTX1 gene, integrated from 10 sources (see all 82):
    (articles sorted by number of sources associating them with NPTX1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mouse and human neuronal pentraxin 1 (NPTX1): conservation, genomic structure, and chromosomal localization. (PubMed id 8884281)1, 2, 3, 9 Omeis I.A.... Perin M.S. (Genomics 1996)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Neuronal pentraxin 1 contributes to the neuronal damage evoked by amyloid-beta and is overexpressed in dystrophic neurites in Alzheimer's brain. (PubMed id 17151277)1, 9 Abad M.A....Trullas R. (J. Neurosci. 2006)
    5. Specific sensitivity of small cell lung cancer cell lines to the snake venom toxin taipoxin. (PubMed id 16115696)1, 9 Poulsen T.T....Poulsen H.S. (Lung Cancer 2005)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    8. Identification of SUMOylated proteins in neuroblastoma cells after treatment with hydrogen peroxide or ascorbate. (PubMed id 21110914)1 Grant M.M. (BMB Rep 2010)
    9. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4884 HGNC: 7952 AceView: NPTX1 Ensembl:ENSG00000171246 euGenes: HUgn4884
    ECgene: NPTX1 H-InvDB: NPTX1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for NPTX1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for NPTX1 gene:
    Search GeneIP for patents involving NPTX1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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