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NPSR1 Gene

protein-coding GIFtS: 51

GC07P034664

neuropeptide S receptor 1
(Previous name: G protein-coupled receptor 154 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: GPR154)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
ASRT2 ^², ⁵
GPR154 ^², ³, ⁵
GPRA ^¹, ², ³, ⁵
NPSR ^²
OTTHUMP00000125228 ^²
OTTHUMP00000125229 ^²
PGR14 ^¹, ², ³, ⁵
VRR1 ^², ⁵

Descriptions
G protein-coupled receptor 154 ^¹, ²
G protein-coupled receptor for asthma susceptibility ^²
G-protein coupled receptor 154 ^³
G-protein coupled receptor PGR14 ^³
G-protein coupled receptor for asthma susceptibility ^³
neuropeptide S receptor 1 ^²
vasopressin receptor-related receptor 1 ^²

External Ids
HGNC: 23631¹
Entrez Gene: 387129²
UniProtKB: Q6W5P4³
Ensembl: ENSG00000187258⁷

Search outside databases for aliases for NPSR1 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for NPSR1:

This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane

protein. Increased expression of this gene in ciliated cells of the respiratory epithelium and in

bronchial smooth muscle cells is associated with asthma. Mutations in this gene have also been

associated with this disease. Alternatively spliced variants which encode different protein

isoforms have been described; however, not all variants have been fully characterized. [provided

by RefSeq]

UniProtKB/Swiss-Prot: NPSR1_HUMAN, Q6W5P4

Function: May be active in signaling pathway in an autocrine or paracrine fashion in several

tissues. Receptor for neuropeptide S, it may mediate its action, such as inhibitory effects, on

cell growth. Involved in pathogenesis of asthma and other IgE-mediated diseases

Gene Wiki entry for NPSR1 (Neuropeptide_S_receptor)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the NPSR1 gene

Entrez Gene cytogenetic band: 7p14.3 Ensembl cytogenetic band: 7p14.3 HGNC cytogenetic band: 7p14.3

NPSR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P034664: (about GC identifiers)

Start:	34,664,422 bp from pter
End:	34,884,469 bp from pter
Size:	220,048 bases
Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 34,742,034-34,962,952

RefSeq DNA sequence:

NC_000007.12 NT_007819.16 NT_079592.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: NPSR1_HUMAN, Q6W5P4 (See protein sequence)

Recommended Name: Neuropeptide S receptor

Size: 371 amino acids; 42687 Da

Subcellular location: Isoform 1: Cell membrane; Multi-pass membrane protein

Subcellular location: Isoform 3: Cell membrane; Multi-pass membrane protein

Subcellular location: Isoform 4: Cell membrane; Multi-pass membrane protein

Subcellular location: Isoform 2: Cytoplasm

Subcellular location: Isoform 5: Cytoplasm

Subcellular location: Isoform 6: Cytoplasm

Subcellular location: Isoform 7: Cytoplasm

Subcellular location: Isoform 9: Cytoplasm

Miscellaneous: Only isoforms with 7 transmembrane topology (isoform 1, isoform 3 and isoform 4) are

transported into the plasma membrane in transfected cells, while the truncated ones retain

intracellular compartments

Secondary accessions: Q2XP58 Q56H76 Q56H77 Q56H78 Q6JSL4 Q6JSL5 Q6JSL6 Q6JSL7 Q6JSL8 Q6W5P3 Q6ZMB8

Alternative splicing: 9 isoforms: Q6W5P4-1 Q6W5P4-2 Q6W5P4-3 Q6W5P4-4 Q6W5P4-5 Q6W5P4-6 Q6W5P4-7 Q6W5P4-8

Q6W5P4-9

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_997055.1 NP_997056.1

ENSEMBL proteins:

ENSP00000334093 ENSP00000370965 ENSP00000370950 ENSP00000379402 ENSP00000353788 ENSP00000370955

ENSP00000370953 ENSP00000352839

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (GPR154)
	Human Recombinant Proteins from Abnova (GPR154)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005886	plasma membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

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Antibodies for NPSR1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for NPSR1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (GPR154), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (GPR154)
	Novus Biologicals Antibodies for NPSR1

Assays for NPSR1:

	Invitrogen Assays for NPSR1
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q6W5P4

ProtoNet protein and cluster: Q6W5P4

UniProtKB/Swiss-Prot: NPSR1_HUMAN, Q6W5P4

Similarity: Belongs to the G-protein coupled receptor 1 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NPSR1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GPR154)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_207172

Applied Biosystems Silencer® siRNAs for NPSR1

Sigma-Aldrich siRNA and siRNA Panels for NPSR1

Sigma-Aldrich shRNA for NPSR1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_207172
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_207172
untagged cDNA clones in CMV expression vector (see all 2): NM_207172

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_207173

UniProtKB/Swiss-Prot: NPSR1_HUMAN, Q6W5P4

Function: May be active in signaling pathway in an autocrine or paracrine fashion in several

tissues. Receptor for neuropeptide S, it may mediate its action, such as inhibitory effects, on

cell growth. Involved in pathogenesis of asthma and other IgE-mediated diseases

3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Npsr1):

homeostasis/metabolism

immune system

respiratory system

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004872	receptor activity	IEA	--
GO:0004930	G-protein coupled receptor activity	IEA	--
GO:0005000	vasopressin receptor activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for NPSR1

5/7 Interacting proteins for NPSR1 (ENSP00000370950³) via UniProtKB, MINT, and/or STRING (see all 7 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ENSG00000197085	ENSP00000350642³	STRING (score=.922)
ADAM33	ENSP00000348912³	STRING (score=.894)
PHF11	ENSP00000367570³	STRING (score=.877)
GPR44	ENSP00000332812³	STRING (score=.848)
PTGDR	ENSP00000303424³	STRING (score=.753)

About this table

2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007165	signal transduction	IEA	--
GO:0007186	G-protein coupled receptor protein signaling pathway	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for NPSR1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (NPSR1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GPR154)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_207172

Sigma-Aldrich siRNA and siRNA Panels for NPSR1

Sigma-Aldrich shRNA for NPSR1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_207172 NM_207173

REFSEQ mRNAs for NPSR1 gene (2 alternative transcripts):

NM_207172.1 NM_207173.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_207172 NM_207173

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_207172
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_207172
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_207172

Additional cDNA sequence:

AK172847.1 AY255536.1 AY310326.1 AY310327.1 AY310328.1 AY310329.1 AY310332.1 AY956446.1

AY956447.1 AY956448.1 BC132693.1 BC132695.1 BC144380.1

5 DOTS entries:

DT.97798466 DT.75119172 DT.121106215 DT.435241 DT.102832532

14 AceView cDNA sequences:

AY310328 AY310331 AY310332 AY310327 AY310330 NM_207172 NM_207173 AY255536

AY310326 AY310329 CD673194 BM828553 AK172847 AI500347

highest scoring ESTs for NPSR1:

AY310327 AY310328 AI500347 NM_207172 NM_207173 AY255536 AY310329 CD673194 AA004400 AA608722

Unigene Cluster for NPSR1:

Neuropeptide S receptor 1

Hs.652373 [show with all ESTs]

Unigene Representative Sequence: AY310326

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for NPSR1

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10
SP1:									-
SP2:									-		-
SP3:							-		-
SP4:							-		-		-
SP5:

About this scheme

ECgene alternative splicing isoforms for NPSR1

8 Ensembl transcripts including schematic representations:

ENST00000334481 ENST00000381553 ENST00000381539 ENST00000396095 ENST00000360581 ENST00000381544

ENST00000381542 ENST00000359791

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

NPSR1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for NPSR1

¹ / ³ Data from (Publications) and GNF BioGPS
About these images

About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.652373
UniProtKB/Swiss-Prot: NPSR1_HUMAN, Q6W5P4
Tissue specificity: Ubiquitous. Isoform 1 is predominantly expressed in smooth muscle, and isoform
4 is predominantly expressed in epithelial cells. In bronchial biopsies, isoform 4 is expressed in
smooth muscle cells of asthma patients, but not in control patients; whereas in epithelial cells,
isoform 4 expression is consistently stronger in asthma patients

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for NPSR1 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	NPSR1¹	--	neuropeptide S receptor 1	88.14(n) 88.95(a)	482394 XM_539511.2 XP_539511.2
chimpanzee (Pan troglodytes)	NPSR1¹	--	neuropeptide S receptor 1	99.01(n) 98.92(a)	747277 XM_001168820.1 XP_001168820.1
cow (Bos taurus)	NPSR1¹	--	neuropeptide S receptor 1	90.72(n) 90.54(a)	519486 XM_864762.2 XP_869855.1
rat (Rattus norvegicus)	Npsr1¹	--	neuropeptide S receptor 1	86.88(n) 89.22(a)	300458 XM_235968.4 XP_235968.4
mouse (Mus musculus)	Npsr1^{1, 5}	9⁵	neuropeptide S receptor 1^{1, 5}	86.61(n)¹ 89.22(a)¹	319239¹ NM_175678.3¹ NP_783609.1¹ AK033957⁵ AK041451⁵ (see all 10)

About this table Species with no ortholog for NPSR1

ENSEMBL Gene Tree for NPSR1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for NPSR1 gene

AVPR2² GPR19²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/1569 NCBI SNPs in NPSR1 are shown (see all 1569 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 652)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs887020^1,2	A,C,F,H,O	34664507(+)	`CACTCG/AGCTGC`	2	--	ut5¹ ese³		13	NA EU EA WA NS	1076
	rs2530543^1,2	A,C,F,H,O	34662484(+)	`TTGTAC/TAGATA`	2	--	ng5¹		10	EU EA WA NA NS	726
	rs1023556^1,2	A,C,F,H,O	34663070(+)	`ATACTC/TATTTG`	2	--	ng5¹		13	EU EA WA NA NS	1050
	rs727162^1,2	A,C,F,H,O	34840563(-)	`GTTTTC/GCTTTT`	2	S/R	mis¹		17	NA EA EU WA NS	1395
	rs2168891^1,2	A,C,F,H,O	34663953(-)	`AGGGCG/AGTTCT`	2	--	ng5¹		13	NA EU EA WA NS	1074
	rs2530545^1,2	A,C,F,H,O	34663665(+)	`CTTCCC/TTGCCT`	2	--	ng5¹		9	NA EU EA WA NS	650
	rs2125404^1,2	A,C,F,H	34663913(-)	`TAAGCT/CACAAC`	2	--	ng5¹		10	EU EA WA NS	932
	rs1023555^1,2	A,C,F,H	34662904(+)	`CCACAT/ACAACT`	2	--	ng5¹		16	NA EA EU WA NS	1321
	rs2530547^1,2	A,C,F,H	34664447(+)	`GCCTCC/TGTTCA`	2	--	ut5¹ ese³		10	EU EA WA NS	916
	rs324981^1,2	A,C,F,H	34784638(+)	`TATTAT/ATTGGC`	2	I/N	mis¹		23	NS EU EA WA NA	1662

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HapMap Linkage Disequilibrium images for NPSR1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 608595 disorders: 608584

UniProtKB/Swiss-Prot: NPSR1_HUMAN, Q6W5P4

NPSR1 is associated with susceptibility to asthma and elevated serum IgE levels

[MIM:608584]. Polymorphisms may influence the development of asthma and bronchial

hyperresponsiveness in adult, and are significantly associated with allergic sensitization and

rhinoconjunctivis, as well as asthma in children

2 Novoseek disease relationships for NPSR1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
asthma allergic	64.66	2	17210045 (2)
asthma	58.97	50	18340359 (4), 15710598 (4), 15947423 (3), 18305139 (3) (see all 11)

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Human Gene Mutation Database: NPSR1
Human Genome Epidemiology Navigator: NPSR1 (14 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/37 PubMed articles for NPSR1 gene (see all 37 ):

Characterization of a common susceptibility locus for asthma-related traits. (PubMed id 15073379)^{2, 3, 4} Laitinen T....Kere J. (2004)
Characterization of GPRA, a novel G protein-coupled receptor related to asthma. (PubMed id 15947423)^{1, 3, 4} Vendelin J....Laitinen T. (2005)
Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma. (PubMed id 15710598)^{1, 3, 4} Melen E.... Nyberg F. (2005)
G-protein-coupled receptor polymorphisms are associated with asthma in a large German population. (PubMed id 15764725)^{3, 4} Kormann M.S.... Kabesch M. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
The G protein-coupled receptor repertoires of human and mouse. (PubMed id 12679517)^{2, 3} Vassilatis D.K.... Gaitanaris G.A. (2003)
G protein-coupled receptor 154 gene polymorphism is associated with airway hyperresponsiveness to methacholine in a Chinese population. (PubMed id 16522461)^{1, 3} Feng Y....Xu X. (2006)
Biological and genetic interaction between tenascin C and neuropeptide S receptor 1 in allergic diseases. (PubMed id 18305139)^{1, 3} Orsmark-Pietras C....Kere J. (2008)
Lack of association between genetic variation in G-protein-coupled receptor for asthma susceptibility and childhood asthma and atopy. (PubMed id 18340359)^{1, 3} Wu H....London S.J. (2008)
Elucidation of signaling properties of vasopressin receptor-related receptor 1 by using the chimeric receptor approach. (PubMed id 14757815)^{1, 3} Gupte J....Tian H. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 387129	HGNC: 23631	AceView: GPR154	Ensembl:ENSG00000187258	euGenes: HUgn387129
ECgene: NPSR1	H-InvDB: NPSR1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
SeattleSNPs	http://pga.gs.washington.edu/data/gpr154/

Licensable Technologies for NPSR1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for NPSR1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for NPSR1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for NPSR1		Antibodies for NPSR1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for NPSR1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (GPR154)
	Antibodies (GPR154)
	Chimera RNAi (GPR154)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (GPR154)
	Antibodies (GPR154)

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Search Tocris compounds for NPSR1

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Antibodies for NPSR1

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NPSR1 Gene

protein-coding GIFtS: 51

Aliases &
Descriptions
for NPSR1

Summaries
for NPSR1

Genomic Location
for NPSR1

Proteins
for NPSR1

Protein Domains/
Families
for NPSR1

Gene Function
for NPSR1

Pathways & Interactions
for NPSR1

Drugs & Compounds
for NPSR1

Transcripts
for NPSR1

Expression
for NPSR1

Orthologs
for NPSR1

Paralogs
for NPSR1

SNPs/Variants
for NPSR1

Disorders & Mutations
for NPSR1

Medical News
for NPSR1

Publications
for NPSR1

Search for NPSR1

Genome Databases showing NPSR1

Other Databases showing NPSR1

Specialized Databases showing NPSR1

Licensable Technologies
for NPSR1

Services
for NPSR1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

NPSR1 Gene

protein-coding GIFtS: 51

Aliases & Descriptionsfor NPSR1

Summariesfor NPSR1

Genomic Locationfor NPSR1

Proteinsfor NPSR1

Protein Domains/Familiesfor NPSR1

Gene Functionfor NPSR1

Pathways & Interactionsfor NPSR1

Drugs & Compoundsfor NPSR1

Transcriptsfor NPSR1

Expression for NPSR1

Orthologsfor NPSR1

Paralogsfor NPSR1

SNPs/Variantsfor NPSR1

Disorders & Mutationsfor NPSR1

Medical Newsfor NPSR1

Publicationsfor NPSR1

Search for NPSR1

Genome Databases showing NPSR1

Other Databases showing NPSR1

Specialized Databases showing NPSR1

Licensable Technologiesfor NPSR1

Servicesfor NPSR1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for NPSR1

Summaries
for NPSR1

Genomic Location
for NPSR1

Proteins
for NPSR1

Protein Domains/
Families
for NPSR1

Gene Function
for NPSR1

Pathways & Interactions
for NPSR1

Drugs & Compounds
for NPSR1

Transcripts
for NPSR1

Expression
for NPSR1

Orthologs
for NPSR1

Paralogs
for NPSR1

SNPs/Variants
for NPSR1

Disorders & Mutations
for NPSR1

Medical News
for NPSR1

Publications
for NPSR1

Licensable Technologies
for NPSR1

Services
for NPSR1