NPSR1 Gene
protein-coding GIFtS: 52
GCID: GC07P034664
|
|
neuropeptide S receptor 1(Previous name: G protein-coupled receptor 154 )
(Previous symbol: GPR154)
| |
Aliases
for NPSR1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Neuropeptide S Receptor 11 2 | | G-Protein Coupled Receptor PGR142 3 | | GPR1541 2 3 5 | | ASRT22 5 | | GPRA1 2 3 5 | | VRR12 5 | | PGR141 2 3 5 | | NPSR2 | | G Protein-Coupled Receptor 1541 2 | | G Protein-Coupled Receptor For Asthma Susceptibility2 | | G-Protein Coupled Receptor 1542 3 | | Neuropeptide S Receptor2 | | G-Protein Coupled Receptor For Asthma Susceptibility2 3 | | Vasopressin Receptor-Related Receptor 12 |
Export aliases for NPSR1 gene to outside databases |
Summaries
for NPSR1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for NPSR1:
This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Increasedexpression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells isassociated with asthma. Mutations in this gene have also been associated with this disease. Alternatively splicedvariants which encode different protein isoforms have been described; however, not all variants have been fullycharacterized. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: NPSR1_HUMAN, Q6W5P4Function: May be active in signaling pathway in an autocrine or paracrine fashion in several tissues. Receptor forneuropeptide S, it may mediate its action, such as inhibitory effects, on cell growth. Involved in pathogenesis ofasthma and other IgE-mediated diseases
Gene Wiki entry for NPSR1 (Neuropeptide S receptor)
|
Genomic Views
for NPSR1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the NPSR1 gene promoter:
Bach1 Pbx1a HTF POU3F2 HNF-3beta C/EBPalpha CHOP-10 HSF2 En-1 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for NPSR1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NPSR1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p14.3 Ensembl cytogenetic band: 7p14.3 HGNC cytogenetic band: 7p14.3NPSR1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P034664: view genomic region
(about GC identifiers)
Start:
|
34,697,851 bp from pter |
End:
|
34,917,944 bp from pter |
Size:
|
220,094 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 34,742,034-34,962,952 |
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Proteins
for NPSR1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NPSR1_HUMAN, Q6W5P4 (See
protein sequence)Recommended Name: Neuropeptide S receptor Size: 371 amino acids; 42687 Da
Subcellular location: Isoform 1: Cell membrane; Multi-pass membrane protein
Subcellular location: Isoform 3: Cell membrane; Multi-pass membrane protein
Subcellular location: Isoform 4: Cell membrane; Multi-pass membrane protein
Subcellular location: Isoform 2: Cytoplasm
Subcellular location: Isoform 5: Cytoplasm
Subcellular location: Isoform 6: Cytoplasm
Subcellular location: Isoform 7: Cytoplasm
Subcellular location: Isoform 9: Cytoplasm
Miscellaneous: Only isoforms with 7 transmembrane topology (isoform 1, isoform 3 and isoform 4) are transported intothe plasma membrane in transfected cells, while the truncated ones retain intracellular compartments
Secondary accessions: A2RTZ4 Q2XP58 Q56H76 Q56H77 Q56H78 Q6JSL4 Q6JSL5 Q6JSL6 Q6JSL7 Q6JSL8 Q6W5P3Q6ZMB8Alternative splicing: 9 isoforms: Q6W5P4-1 Q6W5P4-2 Q6W5P4-3 Q6W5P4-4 Q6W5P4-5 Q6W5P4-6 Q6W5P4-7 Q6W5P4-8 Q6W5P4-9 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for NPSR1: NX_Q6W5P4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6W5P4
NPSR1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_997055.1 NP_997056.1
ENSEMBL proteins: ENSP00000370965 ENSP00000434955 ENSP00000353788 ENSP00000379402 ENSP00000370953 ENSP00000370955 ENSP00000352839 ENSP00000433258 ENSP00000370950 Reactome Protein details: Q6W5P4
Human Recombinant Protein Products for NPSR1:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
NPSR1 for ontologies About GeneDecksing
NPSR1 Antibody Products:
Assay Products for NPSR1: |
Protein
Domains /
Families
for NPSR1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
NPSR1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6W5P4ProtoNet protein and cluster: Q6W5P4 UniProtKB/Swiss-Prot: NPSR1_HUMAN, Q6W5P4Similarity: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily |
Function
for NPSR1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: NPSR1_HUMAN, Q6W5P4Function: May be active in signaling pathway in an autocrine or paracrine fashion in several tissues. Receptor forneuropeptide S, it may mediate its action, such as inhibitory effects, on cell growth. Involved in pathogenesis ofasthma and other IgE-mediated diseases Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005000 | vasopressin receptor activity |
IEA | -- |
NPSR1 for ontologies About GeneDecksing
Phenotypes:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Npsr1):
NPSR1 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Npsr1tm1Bhk for NPSR1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NPSR1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NPSR1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): NPSR1 (NM_207172) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NPSR1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPSR1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPSR1 |
|
Pathways & Interactions
for NPSR1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Class A/1 (Rhodopsin-like receptors) | | | 2 | Signaling by GPCR | | | 3 | G alpha (q) signalling events | | | 4 | G beta:gamma signalling through PLC beta | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/9 
Reactome Pathways for NPSR1 (see all 9)
NPSR1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for NPSR1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/184 Interacting proteins for NPSR1 (ENSP000003528394) via UniProtKB, MINT, STRING, and/or I2D (see all 184)About this table
|
Drugs & Compounds
for NPSR1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
NPSR1 for compounds About GeneDecksing
 Browse Tocris compounds for NPSR1
1 HMDB Compound for NPSR1 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Vasopressin | 3-(Phenylalanine)-8-lysine oxytocin (see all 8) | 11000-17-2 | -- |
1 DrugBank Compound for NPSR1 About this table
1 Novoseek chemical compound relationship for NPSR1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| methacholine |
39.6 |
4 |
16522461 (4) |
Search CenterWatch for drugs/clinical trials and news about NPSR1
|
Transcripts
for NPSR1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for NPSR1 gene (2 alternative transcripts): NM_207172.1 NM_207173.1 Unigene Cluster for NPSR1: Neuropeptide S receptor 1 Hs.652373 [show with all ESTs]Unigene Representative Sequence: AY3103269 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000381553 ENST00000465305 ENST00000360581(uc003teg.1 uc003teh.1)
ENST00000396095(uc010kwu.1) ENST00000381542(uc010kwv.1) ENST00000381544(uc010kwt.1)
ENST00000359791(uc003tei.1) ENST00000531252(uc010kww.1 uc011kar.1)
ENST00000381539
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NPSR1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NPSR1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): NPSR1 (NM_207172) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for NPSR1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPSR1 |
Additional cDNA sequence: AK172847.1 AY255536.1 AY310326.1 AY310327.1 AY310328.1 AY310329.1 AY310332.1 AY956446.1 AY956447.1 AY956448.1 BC132693.1 BC132695.1 BC144380.1 5 DOTS entries: DT.97798466 DT.75119172 DT.121106215 DT.435241 DT.102832532 14 AceView cDNA sequences: AY310326 NM_207173 AY310328 AY310327 AY255536 AY310332 NM_207172 AY310329 AY310331 AY310330 CD673194 AK172847 BM828553 AI500347
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for NPSR1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for NPSR1
|
Expression
for NPSR1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| NPSR1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See NPSR1 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.652373
UniProtKB/Swiss-Prot: NPSR1_HUMAN, Q6W5P4Tissue specificity: Ubiquitous. Isoform 1 is predominantly expressed in smooth muscle. Isoform 4 is predominantlyexpressed in epithelial cells. In bronchial biopsies, it is expressed in smooth muscle cells of asthma patients, butnot in control patients; whereas in epithelial cells, its expression is consistently stronger in asthma patients
SABiosciences Expression via Pathway-Focused PCR Array including NPSR1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NPSR1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat NPSR1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NPSR1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPSR1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPSR1 |
Orthologs
for NPSR1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for NPSR1 gene from 3/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
NPSR11 |
neuropeptide S receptor 1 |
74.03(n)
76.24(a) |
|
428462 XM_426022.2 XP_426022.2 |
lizard
(Anolis carolinensis) |
Reptilia |
NPSR16 |
-- |
71(a) |
1 ↔ 1 |
6(46122642-46151858) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CcapR1 |
Cardioacceleratory peptide receptor |
53.33(n)
44.48(a) |
|
2768688 NM_206574.4 NP_996297.3 |
ENSEMBL Gene Tree for NPSR1 (if available)
TreeFam Gene Tree for NPSR1 (if available) |
Paralogs
for NPSR1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for NPSR1 gene
- GPR1502 AVPR1A2 AVPR1B2 AVPR22 OXTR2 GNRHR2 GNRHR22
4 SIMAP similar genes for NPSR1 using alignment to 2 protein entries: NPSR1_HUMAN (see all proteins):GIR OXTR AVPR2 AVPR1
NPSR1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for NPSR1
PGOHUM00000233171
|
Genomic Variants
for NPSR1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for NPSR1 (34697851 - 34917944 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 11 variations for NPSR1
9 CNVs: 81900 10182 52216 64798 94435 10183 52215 52218 38676
2 Indels: 52217 59407
Human Gene Mutation Database (HGMD): NPSR1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NPSR1 |
|
Disorders
/ Diseases
for NPSR1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
NPSR1 for disorders About GeneDecksing
OMIM gene information: 608595
OMIM disorders: 608584
UniProtKB/Swiss-Prot: NPSR1_HUMAN, Q6W5P4
Defects in NPSR1 are a cause of asthma-related traits type 2 (ASRT2) [MIM:608584]. Asthma-related traitsinclude clinical symptoms of asthma, such as coughing, wheezing, dyspnea, bronchial hyperresponsiveness as assessed bymethacholine challenge test, serum IgE levels, atopy and atopic dermatitis
14  diseases for NPSR1: About MalaCardsasthma attention deficit hyperactivity disorder inflammatory bowel disease atopic dermatitis
panic disorder allergic asthma bronchiolitis eczema
rheumatoid arthritis dermatitis atopy rabies
arthritis schizophrenia
2 diseases from the University of Copenhagen DISEASES database for NPSR1:Asthma Panic disorder 2 Novoseek disease relationships for NPSR1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: NPSR1 (28 documents)
Export disorders for NPSR1 gene to outside databases
|
Publications
for NPSR1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for NPSR1 gene, integrated from 9 sources (see all 69):
(articles sorted by number of sources associating them with NPSR1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of a common susceptibility locus for asthma-related traits. (PubMed id 15073379)1, 2, 3 Laitinen T....Kere J. (2004)
- Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma. (PubMed id 15710598)1, 2, 9 Melen E.... Nyberg F. (2005)
- Characterization of GPRA, a novel G protein-coupled receptor related to asthma. (PubMed id 15947423)1, 2, 9 Vendelin J....Laitinen T. (2005)
- G-protein-coupled receptor polymorphisms are associated with asthma in a large German population. (PubMed id 15764725)1, 2 Kormann M.S.... Kabesch M. (2005)
- Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects. (PubMed id 15312648)1, 2 Xu Y.L....Civelli O. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The G protein-coupled receptor repertoires of human and mouse. (PubMed id 12679517)1, 3 Vassilatis D.K.... Gaitanaris G.A. (2003)
- G protein-coupled receptor 154 gene polymorphism is associated with airway hyperresponsiveness to methacholine in a Chinese population. (PubMed id 16522461)1, 9 Feng Y....Xu X. (2006)
- Biological and genetic interaction between tenascin C and neuropeptide S receptor 1 in allergic diseases. (PubMed id 18305139)1, 9 Orsmark-Pietras C....Kere J. (2008)
- Lack of association between genetic variation in G-protein-coupled receptor for asthma susceptibility and childhood asthma and atopy. (PubMed id 18340359)1, 9 Wu H....London S.J. (2008)
|
External Searches for NPSR1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing NPSR1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing NPSR1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing NPSR1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for NPSR1 | Pharmacogenomics, SNPs, Pathways | | SeattleSNPs | http://pga.gs.washington.edu/data/gpr154/ |
|
| | |
About This Section
| Patent Information for NPSR1 gene:
Search GeneIP for patents involving NPSR1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for NPSR1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for NPSR1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for NPSR1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for NPSR1 | | | OriGene Protein Over-expression Lysate for NPSR1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for NPSR1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for NPSR1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for NPSR1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for NPSR1 | | OriGene Custom Protein Services for NPSR1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat NPSR1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing NPSR1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat NPSR1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat NPSR1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat NPSR1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat NPSR1 |
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| | | | Search Tocris compounds for NPSR1 |
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 | | | NPSR1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for NPSR1 |
|  |  |  |  | | | | ThermoFisher Antibodies for NPSR1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat NPSR1 |
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