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Aliases for NPIPB9 Gene

Aliases for NPIPB9 Gene

  • Nuclear Pore Complex Interacting Protein Family Member B9 2 3 5
  • Nuclear Pore Complex Interacting Protein Family, Member B9 2

External Ids for NPIPB9 Gene

Previous GeneCards Identifiers for NPIPB9 Gene

  • GC16P028782
  • GC16P028783
  • GC16P028752

Summaries for NPIPB9 Gene

GeneCards Summary for NPIPB9 Gene

NPIPB9 (Nuclear Pore Complex Interacting Protein Family Member B9) is a Protein Coding gene. An important paralog of this gene is NPIPB7.

Additional gene information for NPIPB9 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB9 Gene

Genomics for NPIPB9 Gene

Regulatory Elements for NPIPB9 Gene

Enhancers for NPIPB9 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16H029258 1.9 FANTOM5 Ensembl ENCODE dbSUPER 18.7 +521.9 521900 11 HDGF PKNOX1 ATF1 FOXA2 MLX ARID4B SIN3A YBX1 TCF12 FOS SPNS1 ATXN2L NPIPB9 ENSG00000260853 ENSG00000260367 ENSG00000260953 NPIPB10P SMG1P2 NFATC2IP NPIPB8
GH16H028209 1.4 ENCODE dbSUPER 19.4 -531.1 -531126 3 HDGF PKNOX1 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SH2B1 ATXN2L ENSG00000261766 NPIPB9 ENSG00000260853 SPNS1 NFATC2IP ENSG00000260367 RPS15AP33 SGF29
GH16H028821 1.4 ENCODE dbSUPER 10.5 +81.4 81404 4 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC MEF2D SSRP1 TUFM NPIPB12 ENSG00000198106 SH2B1 ATXN2L NPIPB11 ENSG00000260853 CA5AP1 ENSG00000251417 SPNS1
GH16H028973 1.2 ENCODE 12.2 +232.0 231994 2 FOXA2 PKNOX1 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ENSG00000261766 ATXN2L NPIPB12 NFATC2IP ENSG00000260853 SPNS1 CDIPT SULT1A2 ENSG00000247735 NPIPB9
GH16H028844 1.2 ENCODE 9.8 +103.5 103475 2 HDGF FOXA2 PKNOX1 ARID4B SIN3A DMAP1 ZBTB7B YY1 SLC30A9 ZNF766 TUFM ATXN2L NFATC2IP SPNS1 ENSG00000260853 SMG1P2 NPIPB10P ENSG00000260367 NPIPB12 PRRT2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NPIPB9 on UCSC Golden Path with GeneCards custom track

Genomic Location for NPIPB9 Gene

Chromosome:
16
Start:
28,742,728 bp from pter
End:
28,772,850 bp from pter
Size:
30,123 bases
Orientation:
Plus strand

Genomic View for NPIPB9 Gene

Genes around NPIPB9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPB9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPB9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB9 Gene

Proteins for NPIPB9 Gene

  • Protein details for NPIPB9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    F8W1W9-NPIB9_HUMAN
    Recommended name:
    Nuclear pore complex-interacting protein family member B9
    Protein Accession:
    F8W1W9

    Protein attributes for NPIPB9 Gene

    Size:
    429 amino acids
    Molecular mass:
    49181 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPB9 Gene

Post-translational modifications for NPIPB9 Gene

No Post-translational modifications

No data available for DME Specific Peptides for NPIPB9 Gene

Domains & Families for NPIPB9 Gene

Gene Families for NPIPB9 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for NPIPB9 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

F8W1W9

UniProtKB/Swiss-Prot:

NPIB9_HUMAN :
  • Belongs to the NPIP family.
Family:
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB9: view

No data available for Suggested Antigen Peptide Sequences for NPIPB9 Gene

Function for NPIPB9 Gene

Phenotypes From GWAS Catalog for NPIPB9 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB9 Gene

Localization for NPIPB9 Gene

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for NPIPB9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
genes like me logo Genes that share ontologies with NPIPB9: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for NPIPB9 Gene

Pathways & Interactions for NPIPB9 Gene

SuperPathways for NPIPB9 Gene

No Data Available

Interacting Proteins for NPIPB9 Gene

Gene Ontology (GO) - Biological Process for NPIPB9 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NPIPB9 Gene

Drugs & Compounds for NPIPB9 Gene

No Compound Related Data Available

Transcripts for NPIPB9 Gene

mRNA/cDNA for NPIPB9 Gene

(20) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB9 Gene

No ASD Table

Relevant External Links for NPIPB9 Gene

GeneLoc Exon Structure for
NPIPB9
ECgene alternative splicing isoforms for
NPIPB9

Expression for NPIPB9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NPIPB9 Gene

mRNA differential expression in normal tissues according to GTEx for NPIPB9 Gene

This gene is overexpressed in Testis (x6.5).

NURSA nuclear receptor signaling pathways regulating expression of NPIPB9 Gene:

NPIPB9
genes like me logo Genes that share expression patterns with NPIPB9: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NPIPB9 Gene

Orthologs for NPIPB9 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 34
  • 92 (a)
ManyToMany
-- 34
  • 91 (a)
ManyToMany
-- 34
  • 89 (a)
ManyToMany
-- 34
  • 87 (a)
ManyToMany
-- 34
  • 71 (a)
ManyToMany
Species where no ortholog for NPIPB9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB9 Gene

ENSEMBL:
Gene Tree for NPIPB9 (if available)
TreeFam:
Gene Tree for NPIPB9 (if available)

Paralogs for NPIPB9 Gene

Variants for NPIPB9 Gene

Sequence variations from dbSNP and Humsavar for NPIPB9 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000541732 -- 28,750,305(+) AGCGC(A/G)GTTCA intron-variant, upstream-variant-2KB
rs1000645597 -- 28,737,579(+) ATCTG(A/C)TCTCT intron-variant
rs1000866376 -- 28,738,317(+) GATCA(C/T)TAGCG intron-variant
rs1001161887 -- 28,750,723(+) CCGCT(C/T)CCCCA intron-variant, upstream-variant-2KB
rs1001198663 -- 28,739,365(+) AGAAT(C/T)TCTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for NPIPB9 Gene

Variant ID Type Subtype PubMed ID
dgv13n14 CNV gain 18776910
dgv2830n100 CNV gain 25217958
dgv813e212 CNV loss 25503493
esv2758640 CNV gain+loss 17122850
esv3368363 CNV duplication 20981092
nsv1059555 CNV gain 25217958
nsv1064483 CNV loss 25217958
nsv1066415 CNV gain 25217958
nsv1776 CNV deletion 18451855
nsv974890 CNV duplication 23825009
nsv978052 CNV duplication 23825009
nsv978210 CNV duplication 23825009
nsv984301 CNV duplication 23825009

Variation tolerance for NPIPB9 Gene

Gene Damage Index Score: 0.45; 9.94% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NPIPB9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NPIPB9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for NPIPB9 Gene

Disorders for NPIPB9 Gene

Relevant External Links for NPIPB9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NPIPB9

No disorders were found for NPIPB9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB9 Gene

Publications for NPIPB9 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 3 4 60
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for NPIPB9 Gene

Sources for NPIPB9 Gene

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