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Aliases for NPIPB8 Gene

Aliases for NPIPB8 Gene

  • Nuclear Pore Complex Interacting Protein Family, Member B8 2 3

External Ids for NPIPB8 Gene

Previous GeneCards Identifiers for NPIPB8 Gene

  • GC16P028649

Summaries for NPIPB8 Gene

GeneCards Summary for NPIPB8 Gene

NPIPB8 (Nuclear Pore Complex Interacting Protein Family, Member B8) is a Protein Coding gene. An important paralog of this gene is NPIPB11.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB8 Gene

Genomics for NPIPB8 Gene

Genomic Location for NPIPB8 Gene

28,624,517 bp from pter
28,658,725 bp from pter
34,209 bases
Plus strand

Genomic View for NPIPB8 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for NPIPB8 Gene

No data available for Regulatory Elements for NPIPB8 Gene

Proteins for NPIPB8 Gene

  • Protein details for NPIPB8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nuclear pore complex-interacting protein family member B8
    Protein Accession:

    Protein attributes for NPIPB8 Gene

    432 amino acids
    Molecular mass:
    49617 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPB8 Gene

Proteomics data for NPIPB8 Gene at MOPED

Post-translational modifications for NPIPB8 Gene

No Post-translational modifications

Other Protein References for NPIPB8 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for NPIPB8 Gene

Domains & Families for NPIPB8 Gene

Protein Domains for NPIPB8 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NPIP family.
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB8: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for NPIPB8 Gene

Function for NPIPB8 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB8 Gene

Localization for NPIPB8 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NPIPB8 Gene

Pathways & Interactions for NPIPB8 Gene

SuperPathways for NPIPB8 Gene

No Data Available

Interacting Proteins for NPIPB8 Gene

Gene Ontology (GO) - Biological Process for NPIPB8 Gene


No data available for Pathways by source and SIGNOR curated interactions for NPIPB8 Gene

Drugs & Compounds for NPIPB8 Gene

No Compound Related Data Available

Transcripts for NPIPB8 Gene

mRNA/cDNA for NPIPB8 Gene

(16) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB8 Gene

No ASD Table

Relevant External Links for NPIPB8 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NPIPB8 Gene

mRNA expression in normal human tissues for NPIPB8 Gene

mRNA differential expression in normal tissues according to GTEx for NPIPB8 Gene

This gene is overexpressed in Testis (x10.5).
genes like me logo Genes that share expression patterns with NPIPB8: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for NPIPB8 Gene

Orthologs for NPIPB8 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB8 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 36
  • 82 (a)
-- 36
  • 87 (a)
-- 36
  • 85 (a)
-- 36
  • 89 (a)
-- 36
  • 91 (a)
Species with no ortholog for NPIPB8:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB8 Gene

Gene Tree for NPIPB8 (if available)
Gene Tree for NPIPB8 (if available)

Paralogs for NPIPB8 Gene

genes like me logo Genes that share paralogs with NPIPB8: view

Variants for NPIPB8 Gene

Sequence variations from dbSNP and Humsavar for NPIPB8 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs181183 -- 28,651,879(+) gcctc(C/G)gcctc intron-variant
rs389266 -- 28,658,513(-) TTGGG(C/T)TTGGG synonymous-codon, reference
rs389271 -- 28,658,507(-) TTGGG(C/T)GATTG synonymous-codon, reference
rs1054098 -- 28,639,954(-) AGTAC(A/T)CAATG intron-variant
rs1061042 -- 28,636,905(+) CAATA(C/T)CGATT upstream-variant-2KB, intron-variant

Variation tolerance for NPIPB8 Gene

Gene Damage Index Score: 9.01; 87.43% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NPIPB8 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NPIPB8 Gene

Disorders for NPIPB8 Gene

Relevant External Links for NPIPB8

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with NPIPB8: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB8 Gene

Publications for NPIPB8 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 67

Products for NPIPB8 Gene

Sources for NPIPB8 Gene

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