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Aliases for NPIPB7 Gene

Aliases for NPIPB7 Gene

  • Nuclear Pore Complex Interacting Protein Family Member B7 2 3 5
  • Nuclear Pore Complex-Interacting Protein-Like 1 3 4
  • NPIPL1 3 4
  • Nuclear Pore Complex Interacting Protein Family, Member B7 2
  • Nuclear Pore Complex Interacting Protein-Like 1 2
  • A-575C2.4 3
  • A-761H5.5 3

External Ids for NPIPB7 Gene

Previous HGNC Symbols for NPIPB7 Gene

  • NPIPL1

Previous GeneCards Identifiers for NPIPB7 Gene

  • GC16M028469

Summaries for NPIPB7 Gene

GeneCards Summary for NPIPB7 Gene

NPIPB7 (Nuclear Pore Complex Interacting Protein Family Member B7) is a Pseudogene. An important paralog of this gene is NPIPB9.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB7 Gene

Genomics for NPIPB7 Gene

Regulatory Elements for NPIPB7 Gene

Enhancers for NPIPB7 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F028291 0.6 ENCODE 20.3 +178.5 178532 2.5 PKNOX1 MLX ZFP64 ARID4B SIN3A ZNF2 SLC30A9 ZNF766 ZNF143 DEK NPIPB7 SULT1A2 NPIPB9 NPIPB6 EIF3C CDC37P1 ENSG00000246465 GC16P028319
GH16F028542 1.2 FANTOM5 Ensembl ENCODE 12.2 -72.2 -72168 2.1 HDGF PKNOX1 ARNT MLX CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 SULT1A2 TUFM NUPR1 NPIPB7 APOBR CLN3 CD19 RABEP2 IL27 ENSG00000251417
GH16F028525 0.2 ENCODE 12.1 -56.1 -56124 3.8 MLX ARID4B DMAP1 YY1 SLC30A9 ZNF766 KLF13 SP3 SP5 NFYC SULT1A2 TUFM CLN3 APOBR NPIPB7 SGF29 ENSG00000261766 ENSG00000251417 IL27 PIR42560
GH16F028531 1.6 FANTOM5 Ensembl ENCODE 12.1 -62.6 -62605 4.2 ELF3 CBX3 ARID4B RAD21 RARA YY1 ZNF121 ZNF366 MIXL1 SMARCA5 SULT1A2 TUFM APOBR NPIPB7 SGF29 CLN3 IL27 ENSG00000251417 SULT1A1 SPNS1
GH16F028585 0.2 ENCODE 11.5 -114.7 -114739 0.9 TBP ELF3 PKNOX1 ARID4B DMAP1 THRB DNMT3B RARA ZNF766 ZNF366 SGF29 NPIPB7 ENSG00000246465 SBK1 GC16P028596 GC16M028560
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around NPIPB7 on UCSC Golden Path with GeneCards custom track

Genomic Location for NPIPB7 Gene

Chromosome:
16
Start:
28,456,372 bp from pter
End:
28,471,296 bp from pter
Size:
14,925 bases
Orientation:
Minus strand

Genomic View for NPIPB7 Gene

Genes around NPIPB7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPB7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPB7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB7 Gene

Proteins for NPIPB7 Gene

  • Protein details for NPIPB7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75200-NPIB7_HUMAN
    Recommended name:
    Nuclear pore complex-interacting protein family member B7
    Protein Accession:
    O75200
    Secondary Accessions:
    • E7ERT9

    Protein attributes for NPIPB7 Gene

    Size:
    414 amino acids
    Molecular mass:
    47714 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC27429.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for NPIPB7 Gene

Post-translational modifications for NPIPB7 Gene

  • Glycosylation at Asn 111
  • Modification sites at PhosphoSitePlus

Other Protein References for NPIPB7 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for NPIPB7 Gene

Domains & Families for NPIPB7 Gene

Protein Domains for NPIPB7 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for NPIPB7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O75200

UniProtKB/Swiss-Prot:

NPIB7_HUMAN :
  • Belongs to the NPIP family.
Family:
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB7: view

No data available for Gene Families for NPIPB7 Gene

Function for NPIPB7 Gene

genes like me logo Genes that share phenotypes with NPIPB7: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB7 Gene

Localization for NPIPB7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB7 Gene

Secreted.

Gene Ontology (GO) - Cellular Components for NPIPB7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with NPIPB7: view

No data available for Subcellular locations from COMPARTMENTS for NPIPB7 Gene

Pathways & Interactions for NPIPB7 Gene

SuperPathways for NPIPB7 Gene

No Data Available

Interacting Proteins for NPIPB7 Gene

Gene Ontology (GO) - Biological Process for NPIPB7 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NPIPB7 Gene

Transcripts for NPIPB7 Gene

mRNA/cDNA for NPIPB7 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB7 Gene

No ASD Table

Relevant External Links for NPIPB7 Gene

GeneLoc Exon Structure for
NPIPB7
ECgene alternative splicing isoforms for
NPIPB7

Expression for NPIPB7 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for NPIPB7 Gene

mRNA differential expression in normal tissues according to GTEx for NPIPB7 Gene

This gene is overexpressed in Testis (x14.7).

NURSA nuclear receptor signaling pathways regulating expression of NPIPB7 Gene:

NPIPB7
genes like me logo Genes that share expression patterns with NPIPB7: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for NPIPB7 Gene

Orthologs for NPIPB7 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 90 (a)
ManyToMany
-- 35
  • 90 (a)
ManyToMany
-- 35
  • 88 (a)
ManyToMany
-- 35
  • 85 (a)
ManyToMany
-- 35
  • 71 (a)
ManyToMany
Species where no ortholog for NPIPB7 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB7 Gene

ENSEMBL:
Gene Tree for NPIPB7 (if available)
TreeFam:
Gene Tree for NPIPB7 (if available)

Paralogs for NPIPB7 Gene

Variants for NPIPB7 Gene

Variation tolerance for NPIPB7 Gene

Gene Damage Index Score: 0.39; 8.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NPIPB7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NPIPB7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for NPIPB7 Gene

Disorders for NPIPB7 Gene

Relevant External Links for NPIPB7

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NPIPB7

No disorders were found for NPIPB7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB7 Gene

Publications for NPIPB7 Gene

  1. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus B.J. … Adams M.D. (Genomics 1999) 3 4 64
  2. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for NPIPB7 Gene

Sources for NPIPB7 Gene

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