Free for academic non-profit institutions. Other users need a Commercial license

Aliases for NPIPB5 Gene

Aliases for NPIPB5 Gene

  • Nuclear Pore Complex Interacting Protein Family, Member B5 2 3

External Ids for NPIPB5 Gene

Summaries for NPIPB5 Gene

GeneCards Summary for NPIPB5 Gene

NPIPB5 (Nuclear Pore Complex Interacting Protein Family, Member B5) is a Protein Coding gene. An important paralog of this gene is NPIPB11.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB5 Gene

Genomics for NPIPB5 Gene

Genomic Location for NPIPB5 Gene

Start:
22,479,121 bp from pter
End:
22,536,521 bp from pter
Size:
57,401 bases
Orientation:
Plus strand

Genomic View for NPIPB5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NPIPB5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB5 Gene

No data available for Regulatory Elements for NPIPB5 Gene

Proteins for NPIPB5 Gene

  • Protein details for NPIPB5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MRT5-NPIB5_HUMAN
    Recommended name:
    Nuclear pore complex-interacting protein family member B5
    Protein Accession:
    A8MRT5
    Secondary Accessions:
    • B4DK13

    Protein attributes for NPIPB5 Gene

    Size:
    1133 amino acids
    Molecular mass:
    126459 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPB5 Gene

Proteomics data for NPIPB5 Gene at MOPED

Post-translational modifications for NPIPB5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for NPIPB5 Gene

Domains for NPIPB5 Gene

Protein Domains for NPIPB5 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

NPIB5_HUMAN
Family:
  • Belongs to the NPIP family.:
    • A8MRT5
genes like me logo Genes that share domains with NPIPB5: view

No data available for Gene Families for NPIPB5 Gene

Function for NPIPB5 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for NPIPB5 Gene

Localization for NPIPB5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB5 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for NPIPB5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with NPIPB5: view

Pathways for NPIPB5 Gene

SuperPathways for NPIPB5 Gene

No Data Available

Interacting Proteins for NPIPB5 Gene

Gene Ontology (GO) - Biological Process for NPIPB5 Gene

None

No data available for Pathways by source for NPIPB5 Gene

Transcripts for NPIPB5 Gene

mRNA/cDNA for NPIPB5 Gene

(8) REFSEQ mRNAs :
(27) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB5 Gene

No ASD Table

Relevant External Links for NPIPB5 Gene

GeneLoc Exon Structure for
NPIPB5
ECgene alternative splicing isoforms for
NPIPB5

Expression for NPIPB5 Gene

mRNA expression in normal human tissues for NPIPB5 Gene

genes like me logo Genes that share expressions with NPIPB5: view

Orthologs for NPIPB5 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 75 (a)
ManyToMany
-- 37
  • 76 (a)
ManyToMany
LOC750787 36
  • 88.33 (n)
  • 81.62 (a)
Species with no ortholog for NPIPB5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB5 Gene

ENSEMBL:
Gene Tree for NPIPB5 (if available)
TreeFam:
Gene Tree for NPIPB5 (if available)

Paralogs for NPIPB5 Gene

genes like me logo Genes that share paralogs with NPIPB5: view

Variants for NPIPB5 Gene

Sequence variations from dbSNP and Humsavar for NPIPB5 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs432580 -- 22,536,757(-) GGCTG(A/G)GGCAG downstream-variant-500B
rs674108 -- 22,528,784(+) ctgca(A/G)cctcc intron-variant
rs1020960 -- 22,535,893(-) CGCTC(A/G)GAAGG reference, synonymous-codon
rs4011091 -- 22,517,761(+) gagtt(C/G)gagac intron-variant
rs4011094 -- 22,517,604(-) gagat(C/T)gtacc intron-variant

Relevant External Links for NPIPB5 Gene

HapMap Linkage Disequilibrium report
NPIPB5

No data available for Structural Variations from Database of Genomic Variants (DGV) for NPIPB5 Gene

Disorders for NPIPB5 Gene

No disorders were found for NPIPB5 Gene.

No data available for UniProtKB/Swiss-Prot for NPIPB5 Gene

Publications for NPIPB5 Gene

  1. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  2. Divergent origins and concerted expansion of two segmental duplications on chromosome 16. (PMID: 11948212) Eichler E.E. … Rocchi M. (J. Hered. 2001) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4

Products for NPIPB5 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate NPIPB5
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for NPIPB5
    • Block miRNA regulation of NPIPB5 using miScript Target Protectors

    Sources for NPIPB5 Gene

    Back to Top

    Content