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Aliases for NPIPB5 Gene

Aliases for NPIPB5 Gene

  • Nuclear Pore Complex Interacting Protein Family Member B5 2 3 5
  • Nuclear Pore Complex Interacting Protein Family, Member B5 2

External Ids for NPIPB5 Gene

Previous GeneCards Identifiers for NPIPB5 Gene

  • GC16P022504
  • GC16P022507

Summaries for NPIPB5 Gene

GeneCards Summary for NPIPB5 Gene

NPIPB5 (Nuclear Pore Complex Interacting Protein Family Member B5) is a Protein Coding gene. An important paralog of this gene is NPIPB11.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB5 Gene

Genomics for NPIPB5 Gene

Regulatory Elements for NPIPB5 Gene

Enhancers for NPIPB5 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around NPIPB5 on UCSC Golden Path with GeneCards custom track

Genomic Location for NPIPB5 Gene

22,479,121 bp from pter
22,536,535 bp from pter
57,415 bases
Plus strand

Genomic View for NPIPB5 Gene

Genes around NPIPB5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPB5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPB5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB5 Gene

Proteins for NPIPB5 Gene

  • Protein details for NPIPB5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nuclear pore complex-interacting protein family member B5
    Protein Accession:
    Secondary Accessions:
    • B4DK13

    Protein attributes for NPIPB5 Gene

    1133 amino acids
    Molecular mass:
    126459 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPB5 Gene

Proteomics data for NPIPB5 Gene at MOPED

Post-translational modifications for NPIPB5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for NPIPB5 Gene

Domains & Families for NPIPB5 Gene

Protein Domains for NPIPB5 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NPIP family.
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB5: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for NPIPB5 Gene

Function for NPIPB5 Gene

Phenotypes for NPIPB5 Gene

GenomeRNAi human phenotypes for NPIPB5:
genes like me logo Genes that share phenotypes with NPIPB5: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB5 Gene

Localization for NPIPB5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB5 Gene

Membrane; Single-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for NPIPB5 Gene

Pathways & Interactions for NPIPB5 Gene

SuperPathways for NPIPB5 Gene

No Data Available

Interacting Proteins for NPIPB5 Gene

Gene Ontology (GO) - Biological Process for NPIPB5 Gene


No data available for Pathways by source and SIGNOR curated interactions for NPIPB5 Gene

Drugs & Compounds for NPIPB5 Gene

No Compound Related Data Available

Transcripts for NPIPB5 Gene

mRNA/cDNA for NPIPB5 Gene

(8) REFSEQ mRNAs :
(27) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB5 Gene

No ASD Table

Relevant External Links for NPIPB5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NPIPB5 Gene

mRNA expression in normal human tissues for NPIPB5 Gene

genes like me logo Genes that share expression patterns with NPIPB5: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for NPIPB5 Gene

Orthologs for NPIPB5 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB5 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC750787 35
  • 88.33 (n)
  • 81.62 (a)
-- 36
  • 75 (a)
-- 36
  • 76 (a)
Species with no ortholog for NPIPB5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB5 Gene

Gene Tree for NPIPB5 (if available)
Gene Tree for NPIPB5 (if available)

Paralogs for NPIPB5 Gene

genes like me logo Genes that share paralogs with NPIPB5: view

Variants for NPIPB5 Gene

Sequence variations from dbSNP and Humsavar for NPIPB5 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs4011091 -- 22,517,761(+) gagtt(C/G)gagac intron-variant, upstream-variant-2KB
rs4011094 -- 22,517,604(-) gagat(C/T)gtacc intron-variant, upstream-variant-2KB
rs4093815 -- 22,529,247(+) TTGTT(A/T)AAAAA intron-variant, upstream-variant-2KB
rs9745306 -- 22,522,042(+) taggc(A/G)cgtgc intron-variant
rs9745333 -- 22,521,960(+) ggtgc(A/G)atctc intron-variant

Variation tolerance for NPIPB5 Gene

Gene Damage Index Score: 1.55; 30.03% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for NPIPB5 Gene

Disorders for NPIPB5 Gene

Relevant External Links for NPIPB5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for NPIPB5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB5 Gene

Publications for NPIPB5 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Divergent origins and concerted expansion of two segmental duplications on chromosome 16. (PMID: 11948212) Eichler E.E. … Rocchi M. (J. Hered. 2001) 3
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for NPIPB5 Gene

Sources for NPIPB5 Gene