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Aliases for NPIPB4 Gene

Aliases for NPIPB4 Gene

  • Nuclear Pore Complex Interacting Protein Family, Member B4 2 3
  • Nuclear Pore Complex Interacting Protein-Like 3
  • 61E3.4 3

External Ids for NPIPB4 Gene

Summaries for NPIPB4 Gene

GeneCards Summary for NPIPB4 Gene

NPIPB4 (Nuclear Pore Complex Interacting Protein Family, Member B4) is a Protein Coding gene. An important paralog of this gene is NPIPB11.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB4 Gene

Genomics for NPIPB4 Gene

Genomic Location for NPIPB4 Gene

21,834,568 bp from pter
21,880,845 bp from pter
46,278 bases
Minus strand

Genomic View for NPIPB4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for NPIPB4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB4 Gene

No data available for Regulatory Elements for NPIPB4 Gene

Proteins for NPIPB4 Gene

  • Protein details for NPIPB4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Nuclear pore complex-interacting protein family member B4
    Protein Accession:

    Protein attributes for NPIPB4 Gene

    1138 amino acids
    Molecular mass:
    126699 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPB4 Gene

Proteomics data for NPIPB4 Gene at MOPED

Post-translational modifications for NPIPB4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for NPIPB4 Gene

Domains & Families for NPIPB4 Gene

Protein Domains for NPIPB4 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the NPIP family.
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB4: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for NPIPB4 Gene

Function for NPIPB4 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB4 Gene

Localization for NPIPB4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB4 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for NPIPB4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with NPIPB4: view

No data available for Subcellular locations from COMPARTMENTS for NPIPB4 Gene

Pathways & Interactions for NPIPB4 Gene

SuperPathways for NPIPB4 Gene

No Data Available

Interacting Proteins for NPIPB4 Gene

Gene Ontology (GO) - Biological Process for NPIPB4 Gene


No data available for Pathways by source and SIGNOR curated interactions for NPIPB4 Gene

Drugs & Compounds for NPIPB4 Gene

No Compound Related Data Available

Transcripts for NPIPB4 Gene

mRNA/cDNA for NPIPB4 Gene

(3) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(22) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB4 Gene

No ASD Table

Relevant External Links for NPIPB4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for NPIPB4 Gene

mRNA expression in normal human tissues for NPIPB4 Gene

genes like me logo Genes that share expression patterns with NPIPB4: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for NPIPB4 Gene

Orthologs for NPIPB4 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB4 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC750787 35
  • 89.77 (n)
  • 81.8 (a)
-- 36
  • 74 (a)
-- 36
  • 75 (a)
Species with no ortholog for NPIPB4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB4 Gene

Gene Tree for NPIPB4 (if available)
Gene Tree for NPIPB4 (if available)

Paralogs for NPIPB4 Gene Pseudogenes for NPIPB4 Gene

genes like me logo Genes that share paralogs with NPIPB4: view

Variants for NPIPB4 Gene

Sequence variations from dbSNP and Humsavar for NPIPB4 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs150641 -- 21,863,772(+) CATCA(C/T)TGCTA intron-variant
rs170133 -- 21,860,774(-) acgag(A/G)tcagg intron-variant
rs173534 -- 21,848,137(+) tgcct(A/G)cctcg intron-variant
rs183643 -- 21,851,494(+) ACACG(C/T)GGGGC intron-variant
rs187441 -- 21,851,555(+) TATCC(A/G)CCAAA intron-variant

Variation tolerance for NPIPB4 Gene

Gene Damage Index Score: 1.41; 27.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NPIPB4 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NPIPB4 Gene

Disorders for NPIPB4 Gene

Relevant External Links for NPIPB4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with NPIPB4: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB4 Gene

Publications for NPIPB4 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 67
  2. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus B.J. … Adams M.D. (Genomics 1999) 67
  3. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PMID: 9039502) Nagase T. … Nomura N. (DNA Res. 1996) 67

Products for NPIPB4 Gene

Sources for NPIPB4 Gene

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