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Aliases for NPIPB4 Gene

Aliases for NPIPB4 Gene

  • Nuclear Pore Complex Interacting Protein Family Member B4 2 3 5
  • Nuclear Pore Complex Interacting Protein Family, Member B4 2
  • Nuclear Pore Complex-Interacting Protein Family Member B4 3
  • Nuclear Pore Complex Interacting Protein-Like 3
  • 61E3.4 3

External Ids for NPIPB4 Gene

Summaries for NPIPB4 Gene

GeneCards Summary for NPIPB4 Gene

NPIPB4 (Nuclear Pore Complex Interacting Protein Family Member B4) is a Protein Coding gene. An important paralog of this gene is NPIPB5.

Additional gene information for NPIPB4 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for NPIPB4 Gene

Genomics for NPIPB4 Gene

Regulatory Elements for NPIPB4 Gene

Enhancers for NPIPB4 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16H021819 1.1 ENCODE 143.2 +60.6 60586 1 HDGF ZFP64 SIN3A FEZF1 ZNF2 YY1 ZNF302 ZNF143 ZNF207 ZNF548 NPIPB4 NPIPB5 NPIPB3 SMG1P3 ENSG00000260635 SMG1P4 SMG1P1 ENSG00000260905 POLR3E MFSD13B
GH16H022296 1.2 ENCODE 72.3 -416.9 -416938 3 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC PPARGC1A ZFP41 NPIPB4 SMG1P3 NPIPB3 NPIPB5 SMG1P1 MFSD13B RRN3P1 C16orf52 SMG1P4 ENSG00000260635
GH16H022006 1.3 FANTOM5 ENCODE 39.6 -127.4 -127413 2 PKNOX1 ATF1 ARID4B SIN3A YY1 ZNF548 ATF7 SP3 ZHX2 MIER2 SMG1P4 SMG1P1 SMG1P3 NPIPB4 NPIPB5 NPIPB3 ENSG00000260635 ENSG00000260905 POLR3E EEF2K
GH16H022194 1.9 FANTOM5 Ensembl ENCODE dbSUPER 24.6 -314.9 -314855 2 HDGF MLX ZFP64 ARID4B SIN3A DMAP1 YBX1 ZNF2 ZBTB7B YY1 SMG1P3 SMG1P1 NPIPB3 C16orf52 NPIPB4 SMG1P4 NPIPB5 POLR3E MFSD13B ENSG00000260635
GH16H021934 1.3 Ensembl ENCODE 31.8 -54.6 -54588 1 HDGF FOXA2 GLI4 ZNF2 ZNF143 ATF7 KLF7 ZNF548 SP3 REST ENSG00000260306 NPIPB5 NPIPB4 ENSG00000260635 MFSD13B SMG1P4 SMG1P1 SMG1P3 C16orf52 NPIPB3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around NPIPB4 on UCSC Golden Path with GeneCards custom track

Genomic Location for NPIPB4 Gene

Chromosome:
16
Start:
21,834,568 bp from pter
End:
21,880,845 bp from pter
Size:
46,278 bases
Orientation:
Minus strand

Genomic View for NPIPB4 Gene

Genes around NPIPB4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
NPIPB4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for NPIPB4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for NPIPB4 Gene

Proteins for NPIPB4 Gene

  • Protein details for NPIPB4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9JG80-NPIB4_HUMAN
    Recommended name:
    Nuclear pore complex-interacting protein family member B4
    Protein Accession:
    C9JG80

    Protein attributes for NPIPB4 Gene

    Size:
    1138 amino acids
    Molecular mass:
    126699 Da
    Quaternary structure:
    No Data Available

neXtProt entry for NPIPB4 Gene

Post-translational modifications for NPIPB4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for NPIPB4 Gene

Domains & Families for NPIPB4 Gene

Gene Families for NPIPB4 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for NPIPB4 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

C9JG80

UniProtKB/Swiss-Prot:

NPIB4_HUMAN :
  • Belongs to the NPIP family.
Family:
  • Belongs to the NPIP family.
genes like me logo Genes that share domains with NPIPB4: view

No data available for Suggested Antigen Peptide Sequences for NPIPB4 Gene

Function for NPIPB4 Gene

Phenotypes From GWAS Catalog for NPIPB4 Gene

Phenotypes for NPIPB4 Gene

GenomeRNAi human phenotypes for NPIPB4:
genes like me logo Genes that share phenotypes with NPIPB4: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for NPIPB4 Gene

Localization for NPIPB4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for NPIPB4 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for NPIPB4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IDA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with NPIPB4: view

No data available for Subcellular locations from COMPARTMENTS for NPIPB4 Gene

Pathways & Interactions for NPIPB4 Gene

SuperPathways for NPIPB4 Gene

No Data Available

Interacting Proteins for NPIPB4 Gene

Gene Ontology (GO) - Biological Process for NPIPB4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for NPIPB4 Gene

Drugs & Compounds for NPIPB4 Gene

No Compound Related Data Available

Transcripts for NPIPB4 Gene

mRNA/cDNA for NPIPB4 Gene

(5) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(22) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for NPIPB4 Gene

No ASD Table

Relevant External Links for NPIPB4 Gene

GeneLoc Exon Structure for
NPIPB4
ECgene alternative splicing isoforms for
NPIPB4

Expression for NPIPB4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for NPIPB4 Gene

NURSA nuclear receptor signaling pathways regulating expression of NPIPB4 Gene:

NPIPB4
genes like me logo Genes that share expression patterns with NPIPB4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for NPIPB4 Gene

Orthologs for NPIPB4 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for NPIPB4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC750787 33
  • 89.77 (n)
-- 34
  • 75 (a)
ManyToMany
-- 34
  • 74 (a)
ManyToMany
Species where no ortholog for NPIPB4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for NPIPB4 Gene

ENSEMBL:
Gene Tree for NPIPB4 (if available)
TreeFam:
Gene Tree for NPIPB4 (if available)

Paralogs for NPIPB4 Gene

Variants for NPIPB4 Gene

Sequence variations from dbSNP and Humsavar for NPIPB4 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000390365 -- 21,852,030(+) ATGTA(C/G)CCATC intron-variant
rs1000740535 -- 21,860,696(+) TGCCA(C/T)CACAT upstream-variant-2KB
rs1002901982 -- 21,840,534(+) CCCTG(A/C)AACCT intron-variant
rs1002954338 -- 21,834,457(+) AAAAT(A/G)ATAAT downstream-variant-500B
rs1005188652 -- 21,843,123(+) ATCTC(A/T)GGAAA intron-variant

Variation tolerance for NPIPB4 Gene

Gene Damage Index Score: 1.41; 27.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for NPIPB4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
NPIPB4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for NPIPB4 Gene

Disorders for NPIPB4 Gene

Relevant External Links for NPIPB4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
NPIPB4

No disorders were found for NPIPB4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for NPIPB4 Gene

Publications for NPIPB4 Gene

  1. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 4 60
  2. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus BJ … Adams MD (Genomics 1999) 3 60
  3. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PMID: 9039502) Nagase T … Nomura N (DNA research : an international journal for rapid publication of reports on genes and genomes 1996) 3 60

Products for NPIPB4 Gene

Sources for NPIPB4 Gene

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